Use of large language models as artificial intelligence tools in academic research and publishing among global clinical researchers by Tanisha Mishra, Edward Sutanto, Rini Rossanti, Nayana Pant, Anum Ashraf, Akshay Raut, Germaine Uwabareze, Ajayi Oluwatomiwa, Bushra Zeeshan

“…Using a cross-sectional design, we surveyed 226 medical and paramedical researchers from 59 countries across 65 specialties, trained in the Global Clinical Scholars’ Research Training certificate program of Harvard Medical School between 2020 and 2024. Majority (57.5%) of these participants practiced in an academic setting with a median of 7 (2,18) PubMed Indexed published articles. 198 respondents (87.6%) were aware of LLMs and those who were aware had higher number of publications (p < 0.001). 18.7% of the respondents who were aware (n = 37) had previously used LLMs in publications especially for grammatical errors and formatting (64.9%); however, most (40.5%) did not acknowledge its use in their papers. 50.8% of aware respondents (n = 95) predicted an overall positive future impact of LLMs while 32.6% were unsure of its scope. 52% of aware respondents (n = 102) believed that LLMs would have a major impact in areas such as grammatical errors and formatting (66.3%), revision and editing (57.2%), writing (57.2%) and literature review (54.2%). 58.1% of aware respondents were opined that journals should allow for use of AI in research and 78.3% believed that regulations should be put in place to avoid its abuse. …”
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Pathogenicity of germline VHL variants is associated with renal cell carcinoma size in von Hippel-Lindau disease by Gustavo H. Mori, Gustavo F. C. Fagundes, Lucas S. Santana, Felipe Freitas-Castro, Ana Caroline F. Afonso, Delmar M. Lourenço Jr., Maria Adelaide A. Pereira, Fabio Y. Tanno, Victor Srougi, Jose L. Chambo, Mauricio D. Cordeiro, William C. Nahas, Ana O. Hoff, Maria Candida B. V. Fragoso, Berenice B. Mendonca, Ana Claudia Latronico, Madson Q. Almeida

“…In contrast, central nervous system (CNS) hemangioblastomas (HBs) (90.47% vs. 53.12%; p = 0.004), pancreatic cysts (76.19% vs. 28.12%; p = 0.001) and RCCs (57.14% vs. 12.5; p = 0.001) were more common in patients with non-missense VHL variants. …”
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Structural equation modeling of the impact of disease activity on inflammatory bowel disease control: the mediating roles of self-efficacy and self-management behaviors by Yongli Zhu, Ke Liu, Jinfeng Jiang, Xin Cheng, Hao Wang, Feiyang Long, Kang Li, Changping Mu, Lijun Cui

“…Drawing on the Common-Sense Model of Self-Regulation (CSM) and related research, this study investigates how IBD activity status influences disease control through both direct and indirect pathways. …”
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Methodological issues of retrospective surveys for measuring mortality of highly clustered diseases: case study of the 2014–16 Ebola outbreak in Bo District, Sierra Leone by Grazia Caleo, Kamalini Lokuge, Katina Kardamanidis, Jane Greig, Jaroslava Belava, Emer Kilbride, Alhaji Sayui Turay, Gbessay Saffa, Ronald Kremer, Francesco Grandesso, Kostas Danis, Armand Sprecher, Gian Luca Di Tanna, Holly Baker, Helen A. Weiss

“…DEFF for non-EVD-specific mortality was 1.87 in the rural area and 0.44 in the urban area. …”
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Roles of the <i>Sec2p</i> Gene in the Growth and Pathogenicity Regulation of <i>Aspergillus fumigatus</i> by Yuhuan Liu, Shumi Shang, Cong Liu, Yichen Liu, Keyang Xu, Dan He, Li Wang

“…Furthermore, this gene positively regulated the autophagy pathway and enhanced CWI pathway gene expression to respond to rapamycin-induced autophagy. …”
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Features and predictive value of 6-min walk test outcomes in interstitial lung disease: an observation study using wearable monitors by Jiaying Li, Xiaobing Wu, Xiaoyan Li, Miaozhen Deng, Xinyin Liang, Huiqun Wei

“…We found significant differences in 6MWD (F=2.44, p=0.033), SpO2 change (F=2.58, p=0.025), HR at 0 min (F=2.87, p=0.014), HR at end of 6 min (F=2.58, p=0.025) and HR zenith (F=2.64, p=0.022) between the subtypes of ILD.Conclusion This observation provided an important evidence regarding oxygen titration. …”
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Social-structural barriers to primary care among sex workers: findings from a community-based cohort in Vancouver, Canada (2014–2021) by Miriam T. H. Harris, Kate Shannon, Andrea Krüsi, Haoxuan Zhou, Shira M. Goldenberg

“…At first available observation, participants faced a high burden of sexually transmitted and blood-borne infections (STBBIs) (48.0%, 11.5%, and 10.4% were HCV, HIV, or STI seropositive, respectively), 56.8% were diagnosed with a mental health disorder, 8.1% had recently overdosed, and 14.7% were recently hospitalized. In multivariable GEE analysis, exposure to intimate partner violence was associated with reduced primary care use (Adjusted odds ratios (AOR) 0.63, 95% Confidence interval (CI): 0.49—0.82), and limited English fluency was marginally associated (AOR 0.76 CI: 0.51—1.14). …”
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Lack of Male-Female Differences in Disposition and Esterase Hydrolysis of Ramipril to Ramiprilat in Healthy Volunteers after a Single Oral Dose by Tom B. Vree, Erik Dammers, Ivan Ulc, Stefan Horkovics-Kovats, Miroslav Ryska, IJsbrand Merkx

“…The groups of female and male volunteers showed similar yields (AUCt = mg.h/L) of the metabolite ramiprilat (p = 0.37); however, females showed a higher AUCt/kg than males (p = 0.046). …”
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Efficacy and Safety of Cataract Surgery Combined with Ab Interno Canaloplasty and Micro-Trabecular Bypass Stent Surgery in Open-Angle Glaucoma by Porter MS, Flowers A, Wood BP, Gallardo MJ

“…In the uncontrolled group (n=27), baseline IOP and number of medications were 21.9± 3.1 and 1.9± 1.3 and reduced to 14.6± 4.2 (p=0.006) and 1.7± 1.6 (p=0.821) at 36 months postoperatively. …”
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Faktor-Faktor yang Berhubungan dengan Kejadian Obesitas pada Mahasiswa Fakultas Ilmu Kesehatan Universitas Pembangunan Nasional “Veteran” Jakarta by Fairy Amara Rahadian, Utami Wahyuningsih, Sintha Fransiske Simanungkalit

“…Data dikumpulkan menggunakan kuesioner dan pengukuran antropometri yang kemudian dianalisis menggunakan uji Chi-Square. Hasil: Hasil analisis statistik menunjukkan bahwa frekuensi konsumsi makanan manis memiliki p-value (0,111), frekuensi minuman manis (p-value=0,733), frekuensi makanan tinggi lemak (p-value=0,036), asupan manis (p-value=1,000), asupan tinggi lemak (p-value=0,426), asupan serat (p-value=0,819), perilaku emotional eating (p-value=0,057), external eating (p-value=0,871), aktivitas fisik (p-value=0,271), dan p-value tingkat stres (1,000). …”
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Assessment of phytochemical screening, antibacterial, analgesic, and antipyretic potentials of Litsea glutinosa (L.) leaves extracts in a mice model. by Zubair Khalid Labu, Samira Karim, Md Tarekur Rahman, Md Imran Hossain, Sarder Arifuzzaman, Md Shakil

“…Analgesic activity at 500 mg/kg, LG extract produced a 70% suppression of writhing in mice, which was statistically significant (p < 0.001) compared to standard morphine's (77.5%) inhibition. In antipyretic activity assay, the crude extract showed notable reduction in body temperature (36.17 ±  0.32 °C) at dose of 300 mg/kg-body weight, when the standard (at dose 100 mg/kg-body weight) exerted (36.32 ±  0.67 °C) after 3 h of administration. …”
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Incidence of cancer-related lymphoedema: a protocol for a living systematic review with meta-analysis by Nele Devoogdt, Hildegard Reul-Hirche, Kira Bloomquist, Michael Bernas, Ben Singh, Sandi Hayes, Melanie Plinsinga, Debbie Geyer, Louise Koelmeyer, Neil Piller, Stanley Rockson

“…Subgroup analyses that explore relationships between lymphoedema incidence and lymphoedema measurement method, time since cancer diagnosis and treatment and diagnosis, treatment and behavioural characteristics will be conducted dependent on available data.Ethics and dissemination This living systematic review enables clinicians and researchers to consult a contemporary, comprehensive overview of the incidence of cancer-related lymphoedema and the association between lymphoedema and treatment and non-treatment-related risk factors.PROSPERO registration number CRD42022333291.…”
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اولویت‌بندی خطر سیل در حوضه آبخیز گنجوان استان ایلام با استفاده از مدل الکتره by فتح الله نادری, بهروز ناصری, یاسم خانمحمدیان, عماد سلامت, محمدتقی کوشا

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Evaluación del impacto del COVID-19 en la frecuencia de trastornos psicológicos en estudiantes de medicina de la Universidad Antofagasta. by Marcia Pereyra, Margarita Fuentes, Maria Jose Navarro, Francisco Montenegro, Karina Diaz, Camila Bradanovic, Carolina Madero, Elainne Doll, Valentina Delgado

“…En el área de la salud mental la puntuación global fue muy alto (31,7 de 38) indicando que hay posibilidad de que los estudiantes sufrieron un trastorno emocional que demostró un peor estado de salud mental, siendo el estado de ánimo el área más afectada. …”
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Effectiveness of women-led community interventions in improving tuberculosis preventive treatment in children: results from a comparative, before–after study in Ethiopia by Jacob Creswell, Degu Jerene, Ahmed Bedru, Dawit Assefa, Kalkidan Tesfaye, Samuel Bayu, Samuel Seid, Fikirte Aberra, Amera Khan

“…TPT initiation rate for U5C increased from 13% (17 out of 131) to 93% (937 out of 1010). …”
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UK medical students’ mental health and their intention to drop out: a longitudinal study by Asta Medisauskaite, Antonia Rich, Milou Silkens, Neha Lagisetty

“…Those students who were more emotionally exhausted (Badjusted=0.94, p&lt;0.0001) and expressed higher anxiety/depression symptoms (Badjusted=1.12, p&lt;0.0001), insomnia symptoms (Badjusted=0.69, p&lt;0.0001), somatisation symptoms (Badjusted=0.77, p&lt;0.0001), anorexia tendencies (Badjusted=−0.84, p&lt;0.0001), OCD symptoms (Badjusted=0.61, p&lt;0.0001) and paranoia symptoms (Badjusted=0.52, p&lt;0.0001) expressed significantly stronger intentions to leave their medical education. …”
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Temporal trends and future projections of incidence rate and mortality for asthma in China: an analysis of the Global Burden of Disease Study 2021 by Xi Chen, Xi Chen, Dandan Ma, Hangyu Li, Yilin Liu, Guixing Xu, Xinyu Deng, Qi Li, Junqi Li, Hui Pan

“…The ASIR of asthma decreased from 524.81 to 364.17 and the ASMR declined from 5.82 to 1.47. ASIR and ASMR are consistently higher in males than females during this period. …”
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Mild ultrasound-assisted alkali de-esterification modified pectins: Characterization and structure–activity relationships in immunomodulatory effects by Huan Guo, Dong Li, Baohe Miao, Kanglin Feng, Guijing Chen, Renyou Gan, Zhiliang Kang, Hong Gao

“…The molecular weights of AP-E1, AP-E2, and AP-E3 were determined to be 30.94 ± 0.83 kDa, 27.61 ± 0.65 kDa, and 22.17 ± 0.57 kDa, respectively. …”
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Association Between Screen Time and Lifestyle Parameters with Executive Functions in Chilean Children and Adolescents: Potential Mediating Role of Health-Related Quality of Life by Felipe Caamaño-Navarrete, Carlos Arriagada-Hernández, Lorena Jara-Tomckowiack, Jordan Hernandez-Martinez, Pablo Valdés-Badilla, Guido Contreras-Díaz, Indya del-Cuerpo, Pedro Delgado-Floody

“…<b>Results</b>: Attention was inversely associated with ST (β = −19.51, <i>p</i> < 0.001) and positively associated with HRQoL (β = 4.17, <i>p</i> < 0.001). Inhibition was negatively linked to ST (β = −25.17, <i>p</i> < 0.001) and positively associated with HRQoL (β = 3.23, <i>p</i> = 0.041). …”
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Nutrient availability in tropical soils fertilized with sewage sludge and natural phosphate by Rodinei Facco Pegoraro, Jefferson Rodrigo Teixeira Silva, Leidivan Almeida Frazão, Regynaldo Arruda Sampaio, Silvana Ferreira Bicalho, Verônica Aparecida Santos Ferreira Soares

“…At 120 days after application of sludge, the average availability rate of P, K, Ca, and Mg corresponded to 37, 13, 144, and 157%, respectively. …”
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