Coagulation Parameters in Elderly Patients with Severe Pneumonia: Correlation with Disease Severity and Prognosis by Zhang Q, Liu Y, Tong C, Zhang L, Li R, Guo W, Li J

“…Qiuyue Zhang,1,* Yingchao Liu,1,* Chuntang Tong,2 Lina Zhang,3 Rongchen Li,1 Wenbin Guo,4 Jianliang Li5 1Department of Clinical Laboratory, The Second People’s Hospital of Liaocheng, Linqing, Shandong, 252600, People’s Republic of China; 2Department of Respiratory Medicine, The Second People’s Hospital of Liaocheng, Linqing, Shandong, 252600, People’s Republic of China; 3Department of Scientific Research Management Division, The Second People’s Hospital of Liaocheng, Linqing, Shandong, 252600, People’s Republic of China; 4Department of Intensive Care Unit, The Second People’s Hospital of Liaocheng, Linqing, Shandong, 252600, People’s Republic of China; 5Department of Thoracic Surgery, The Second People’s Hospital of Liaocheng, Linqing, Shandong, 252600, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jianliang Li, Department of Thoracic Surgery The Second People’s Hospital of Liaocheng, 306 health Street, Linqing, Shandong, 252600, People’s Republic of China, Tel +86 15020622456, Email lijianliangl724@163.comObjective: This study aimed to investigate the levels of coagulation parameters in elderly patients with severe pneumonia and analyse their correlation with disease severity and prognosis.Methods: A retrospective study was conducted on 207 elderly patients (aged ≥ 60 years) with severe pneumonia admitted to our hospital between January 2022 and December 2023. …”
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Potential role of P4HB in the tumor microenvironment and its clinical prognostic value: a comprehensive pan-cancer analysis and experimental validation with a focus on KIRC by Linxue Zhang, Yu-wei Li, Tianyi Xie, Ke Sun, Xiang Huang, Wei Xiong, Rui-ji Liu

“…Moreover, multivariate cox regression analysis indicated that P4HB (HR = 1.372, 95% CI 1.047–1.681, P = 0.019) was an independent risk factor for OS in KIRC. …”
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Risk factors and preventive measures for severe orofacial and neck infections: a three-year observational study by Jarno Velhonoja, Meira Lääveri, Tero Soukka, Saara Haatainen, Noora Al-Neshawy, Ilpo Kinnunen, Heikki Irjala

“…The spaces most often involved were the submandibular (n = 15; 16.0%), sublingual (n = 15; 16.0%) and parapharyngeal (n = 14; 14.9%) spaces. Sixty-three cases (67.0%) were of odontogenic origin, and 58.5% of the patients reported having attended previous health care appointments due to an acute dental problem. …”
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Risk factors associated with the failure of local methotrexate combined with minimally invasive surgery for late cesarean scar pregnancy by Xiao-Tong Cheng, Yan-Song Liu, Dan-Yang Song, Xiao-Cui Nie, Yu-Shi Xiang, Ju-Min Niu

“…Subsequent binary logistic regression analysis revealed the following independent risk factors linked to the failure of the initial combined treatment: baseline serum β-hCG levels exceeding 94,000 IU/L [odds ratio (OR) 3.060, 95% confidence interval (CI) 1.387–6.749, P = 0.006], type III CSP (OR 3.574, 95% CI 1.147–11.135, P = 0.028), a time interval greater than seven days between MTX and surgery (OR 3.847, 95% CI 1.725–8.581, P = 0.001), and the presence of a fetal heartbeat before surgery (OR 4.405, 95% CI 1.014–19.128, P = 0.048). …”
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Antimicrobial resistance in clinical <I>Escherichia coli</I> isolates obtained from animals by M. N. Isakova, O. V. Sokolova, N. A. Bezborodova, A. S. Krivonogova, A. G. Isaeva, V. D. Zubareva

“…The article presents data on the phenotypic and genotypic characteristics of antimicriobial resistance in Escherichia coli clinical isolates recovered from bovine microbiota (secretions from mammary glands, cervical swabs). 127 Escherichia coli isolates were studied, i.e. 44 from mammary glands secretions and 83 from cervical swabs. …”
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Efficacy Study of Carrageenan as an Alternative Infused Material (Filler) in Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Porous 3D Scaffold by Nor Syamimi Che Johari, Syazwan Aizad, Saiful Irwan Zubairi

“…Therefore, this research attempts to overcome the weaknesses by using carrageenan from red seaweed Kappaphycus alvarezii as an alternative infused material (filler) of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) porous 3D scaffold. …”
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Incidence of HTLV-1-associated myelopathy in the UK from 1991 to 2024: a longitudinal observational cohort study by Carolina Rosadas, Jerico Baylon, Claire Greiller, Adine Adonis, Divya Dhasmana, Nicholas W. S. Davies, Graham P. Taylor, Graham P. Taylor

“…At the first visit, the HTLV-1 proviral load was compared between incident cases and those who remained asymptomatic during follow-up.ResultsIn a cohort with up to 33 years of follow-up of individuals living with HTLV-1 in the UK, the cumulative incidence of HTLV-1-associated myelopathy (HAM) was found to be 1.35% (4/297), with an incidence rate of 1.98 per 1,000 person-years. …”
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Efficacy and safety of Lutai Danshen Baishao granules for treating female melasma: A randomized, double-blind, placebo-controlled trial by Meiyu Lyu, Yi Yang, Jinlian Liu, Wenting Fei, Min Fu, Yunting Hong, Hongguo Rong, Chun Wang, Linyuan Wang, Jianjun Zhang

“…The total TCM symptom evaluation score significantly decreased (test group: 6.00 vs. placebo group: 7.00, P = .001), with significant relief in symptoms such as improvement in dark lips, nails, and waist soreness in the test group, compared with that in the placebo group (P < .05). …”
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Fatores associados ao conhecimento de locais públicos de esporte e lazer nas capitais brasileiras by Paula Agrizzi, Thalia Eloisa Pereira Sousa Dourado, Juliana Ilídio da Silva, Amanda Cristina de Souza Andrade

“…Realizou-se análise bivariada através do teste Qui-quadrado e correlação de Pearson. Dos 27.017 entrevistados, 56,6% (IC95%: 55,1 - 58,1) relataram conhecer locais públicos de esporte e lazer, sendo maior entre homens (58,2% vs 55,3%) e mais escolarizados (45,5% de 0 a 4; 49,2% de 5 a 8; 55,2% de 9 a 11; 68,2% de 12 anos ou mais). …”
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Positive Associations between Adipocyte Fatty Acid-Binding Protein Level and Central Arterial Stiffness in Peritoneal Dialysis Patients by Cheng-Hao Sung, Bang-Gee Hsu, Jen-Pi Tasi, Chih-Hsien Wang, Chiu-Huang Kuo

“…Furthermore, serum A-FABP levels (β = 0.476, adjusted R2 change: 0.197, P < 0.001) were significantly positively correlated with cfPWV according to the multivariable forward stepwise linear regression analysis. …”
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Problem of pain in the USA: evaluating the generalisability of high-impact chronic pain models over time using National Health Interview Survey (NHIS) data by Sean Mackey, Titilola Falasinnu, Md Belal Hossain, Mohammad Ehsanul Karim, Kenneth Arnold Weber

“…De novo models based on 2021 data showed comparable discrimination (AUC: 0.86, 95% CI 0.85 to 0.87) but poorer calibration when validated against older datasets.Conclusion These findings underscore the potential of these models to guide personalised medicine strategies for HICP, aiming for more preventive rather than reactive healthcare. …”
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Dyslipidemia Impacts Cardiometabolic Health and CVD Risk in a Relatively Young Otherwise Healthy Population by Jillian M. Lang, Elena S. Shostak, William K. Quinn, Valerie D. Chervinskaya, Elisa Fioraso, Everett Smith, Christopher J. Kotarsky, Justin A. DeBlauw, Jennifer L. Lloyd, Stephen J. Ives

“…ABSTRACT Dyslipidemia, abnormal levels of lipids in the bloodstream, is associated with cardiovascular disease risk (CVD). The purpose of this study was to evaluate the effects of dyslipidemia on cardiometabolic health in relatively young, healthy adults. …”
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Monkeypox-related knowledge and vaccination willingness among HIV-diagnosed and -suspected males: a cross-sectional survey in Changsha by Yingying Zhou, Jiemin Wang, Zhi Xie

“…Participants in the age groups ranging 25–34 (aOR = 0.287, 95% CI: 0.086–0.959) and 35–44 (aOR = 0.136, 95% CI: 0.039–0.478) years showed a lower level of vaccination willingness, referred to the 15–24 year age group. …”
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Preoperative Altered Spontaneous Brain Activity and Functional Connectivity Were Independent Risk Factors for Delayed Neurocognitive Recovery in Older Adults Undergoing Noncardiac... by Zhaoshun Jiang, Xixue Zhang, Yating Lv, Xiaodong Zheng, Huibiao Zhang, Xuelin Zhang, Chongyi Jiang, Guangwu Lin, Weidong Gu

“…The multivariate logistic regression analysis showed that higher preoperative spontaneous activity in the bilateral MCC was independently associated with a higher risk of DNR (OR=3.11, 95% CI, 1.30-7.45; P=0.011). A longer education duration (OR=0.57, 95% CI, 0.41-0.81; P=0.001) and higher preoperative FC between the bilateral MCC and left calcarine (OR=0.40, 95% CI, 0.18-0.92; P=0.031) were independently correlated with a lower risk of DNR. …”
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Classification and Recognition Method for Bearing Fault based on IFOA-SVM by Wei Zhang, Zhihua Ma

“…></graphic><graphic specific-use="small" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="alternativeImage/CBC0F59B-F91E-4c39-864E-1346B6B72A10-M003c.jpg"><?…”
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Influence of Sweetness and Ethanol Content on Mead Acceptability by Gomes Teresa, Dias Teresa, Cadavez Vasco, Verdial João, Morais Jorge Sá, Ramalhosa Elsa, Estevinho Letícia M.

“…Low concentrations of acetic acid were determined (0.46±0.08 and 0.57±0.09 g/L), avoiding the vinegar off-character. …”
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Structural Disruption of Cilia and Increased Cytoplasmic Tubulin in Biliary Atresia—An Exploratory Study Focusing on Early Postoperative Prognosis Following Portoenterostomy by Patrícia Quelhas, Rui Oliveira, Carlos Kieling, Sandra Vieira, Jorge dos Santos

“…While the PC ratio per biliary structure (cilia ratio status, CRs) was similar between BA patients and controls, PC length was decreased in BA patients. …”
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Exploring the Prognostic Role of Trop-2, CD47, and CD163 Expression Levels on Survival Outcomes in Patients with Triple-Negative Breast Cancer by Ramazan Oguz Yüceer, Sedanur Aydın, Iclal Gelir, Tulay Koc, Ersin Tuncer, Mahmut Ucar

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Gut Microbiota, Microinflammation, Metabolic Profile, and Zonulin Concentration in Obese and Normal Weight Subjects by Agnieszka Żak-Gołąb, Piotr Kocełak, Małgorzata Aptekorz, Maria Zientara, Łukasz Juszczyk, Gayane Martirosian, Jerzy Chudek, Magdalena Olszanecka-Glinianowicz

“…Additionally, plasma zonulin level was proportional to daily energy intake (r=0.27, P<0.05) and serum glucose concentration (r=0.18, P<0.05) and inversely proportional to diet protein percentage (r=-0.23, P<0.05). …”
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Selective posterior rhizotomy for the treatment of pure hereditary spastic paraplegia⁃ associated lower limb spasticity by TANG Nan, SHEN Yin, WANG Lei, ZHENG Jiang‐lin, HUANG Ning, ZHOU Ying‐chun

“…The GMFCS score before and 12 months after surgery were no significantly different (t = 1.000, P = 0.347). Conclusions SPR has good efficacy and safety for the treatment of PHSP⁃associated lower limb spasticity.…”
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