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4381
Clinical outcomes of chimeric antigen receptor T-cell therapy following autologous hematopoietic stem cell transplantation in 38 patients with refractory/relapsed primary or second...
Published 2024-11-01“…Among the 25 patients with secondary CNSL (SCNSL), the best ORRs were 91.7% for those with CNS lesions only and 61.5% for those with CNS and systemic lesions (P = 0.160), while the estimated 1-year PFS rates were 83.3% and 38.5%, respectively (P = 0.030). …”
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4382
Anisotropic robust Poly(vinyl alcohol) hydrogels inspired by bio-tissue
Published 2025-02-01“…The tensile strength and toughness of the resulted PVA hydrogel are 3.7 MPa and 3.27 MJ⋅m−3, which are 7.7 times and 9.9 times greater than those of conventional PVA hydrogels produced by freeze-casting method. …”
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4383
The Dynamic Interplay between the Gut Microbiota and Autoimmune Diseases
Published 2019-01-01Get full text
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4384
UAV Collision Avoidance in Unknown Scenarios with Causal Representation Disentanglement
Published 2024-12-01Get full text
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4385
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4386
Study on the Support System Mechanism of Entry Roof with Roof Cutting Pressure Releasing Gob-Side Entry Retaining Technology
Published 2022-01-01“…Firstly, the stress structure of the roof cutting short beam is analyzed by the mechanical theory analysis method. …”
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4387
Synthetic transmembrane DNA receptors enable engineered sensing and actuation
Published 2025-02-01“…The construction and assembly of synthetic receptor analogs that can mimic such biological processes is a central goal of synthetic biochemistry and bionanotechnology to endow receptors with user-defined signal transduction effects. …”
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4388
Dietary steviol glycosides mixture supplementation modulates the gene expression of gut chemoreceptors and enhances the antioxidant capacity in weaned piglets
Published 2025-02-01“…Furthermore, piglets fed a diet supplemented with 100 mg/kg SGs mixture had higher serum T-SOD, CAT, and GSH-Px activities compared with the other treatments (P < 0.05). …”
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4389
Robot-Assisted Partial Splenectomy for Splenic Epidermoid Cyst
Published 2020-01-01“…The inner wall of the cyst has lining epithelium. The cyst can be unilocular or multilocular. According to pathology, it can be divided into four types: epidermoid cyst, dermoid cyst, cystic lymphangioma, and cystic hemangioma. …”
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4390
Innovative nanoparticle-based approaches for modulating neutrophil extracellular traps in diseases: from mechanisms to therapeutics
Published 2025-02-01“…While they help capture and eliminate pathogens, NETs’ excessive or dysregulated formation can lead to tissue damage and disease progression. …”
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4391
Yiqi Juanshen decoction alleviates renal interstitial fibrosis by targeting the LOXL2/PI3K/AKT pathway to suppress EMT and inflammation
Published 2025-02-01“…YQJSD has been shown to effectively reduce serum creatinine and blood urea nitrogen levels, decrease extracellular matrix deposition, and down-regulate the expression of α-SMA, COL4α1, Fibronectin (FN). Mechanistically, YQJSD exerts its effects by modulating multiple pathways: it inhibits the NF-κB signaling pathway, inhibiting the expression of pro-inflammatory cytokines like NF-κB1, IL-1β, TNF-α, and CCR1. …”
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4392
Circulating Th1, Th2, Th17, Treg, and PD-1 Levels in Patients with Brucellosis
Published 2019-01-01“…The expressions of PD-1 on CD4+ and CD8+ T lymphocytes were significantly different in acute and chronic patients. …”
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4393
The impact of perceived caregiver anxiety and stress during childhood on late-life depression: evidence from the China Health and Retirement Longitudinal Study
Published 2025-01-01“…Depression was measured using the CES-10 depression scale. Multivariate logistic regression models examined the relationship between caregiver anxiety and stress frequency and late-life depression, adjusting for confounders like socioeconomic status, health behaviors, and demographics.ResultsChildhood exposure to caregiver anxiety and stress significantly increased the risk of depression in later life (p < 0.05), with stronger effects observed among individuals with female caregivers. …”
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4394
Chronic restraint stress affects the diurnal rhythms of gut microbial composition and metabolism in a mouse model of depression
Published 2025-01-01“…Methods Chronic restraint stress (CRS) was used to induce depressive-like behaviours in C57BL/6J mice. …”
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4395
Research on integrated injection-production optimization technology of electric submersible pump for Bohai oilfield heavy oil thermal recovery
Published 2025-01-01“…The integrated optimization technology of electric submersible pump injection and production has good stability and applicability, and can be further promoted and applied.…”
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4396
Effect of Lipoxin A4 on Lipopolysaccharide-Induced Endothelial Hyperpermeability
Published 2011-01-01“…Our findings demonstrate that LXA4 could prevent the EC hyperpermeability induced by LPS in human umbilical vein endothelial cells (HUVECs), under which the possible mechanism is through Nrf2 as well as Ca2+-sensitive pathways.…”
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4397
Cassava–soybean intercropping alleviates continuous cassava cropping obstacles by improving its rhizosphere microecology
Published 2025-02-01“…Phenol glucuronide, 2,3-butanediol, L-phenylalanine, deoxyguanosine and other carbohydrates, alcohols, purine nucleotides, and amino acids were significantly positively correlated with organic matter, available nitrogen, soil porosity, and pH.DiscussionTherefore, cassava–soybean intercropping can effectively alleviate the obstacles of continuous cassava cropping by affecting the accumulation of metabolites and microbial community structure in continuous cropping soil, thereby improving the adverse factors of severe soil acidification, soil compaction, and nutrient decline.…”
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4398
Analysis of the Structural Characteristics of the Online Social Network of Chinese Professional Athletes
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4399
lncRNA-SNHG14 Plays a Role in Acute Lung Injury Induced by Lipopolysaccharide through Regulating Autophagy via miR-223-3p/Foxo3a
Published 2021-01-01“…One underlying mechanism is that lncRNA-SNHG14 regulated autophagy by controlling miR-223-3p/Foxo3a as a ceRNA. It suggested that lncRNA-SNHG14 may serve as a potential therapeutic target for patients with sepsis-induced ALI.…”
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4400
Association between the Triglyceride-Glucose Index and the Risk of Large Artery Atherosclerotic Stroke
Published 2022-01-01“…The area under the ROC curve was 0.69 (95% CI: 0.646–0.742, P<0.05), sensitivity was 78.0%, and specificity was 63.4%. …”
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