Parathyroid Adenoma - The Leading Cause of Primary Hyperparathyroidism: Case Report by Martyna Zielnik, Julia Dubel, Szymon Kalinowski, Sabina Kadłubek, Patrycja Rembisz, Anna Czuba, Pola Knurowska, Klaudia Serafin, Aleksander Wrona, Aleksandra Słowikowska

“…The predominant etiology of primary hyperparathyroidism is the presence of a parathyroid adenoma. (7) This case report presents a 68-year-old female patient with a history of osteoporosis, diagnosed in 2019 for osteoarticular pain and hypercalcemia. …”
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MDTR: a knowledge-guided interpretable representation for quantifying liver toxicity at transcriptomic level by Inyoung Sung, Sangseon Lee, Dongmin Bang, Dongmin Bang, Jungseob Yi, Sunho Lee, Sun Kim, Sun Kim, Sun Kim, Sun Kim

“…Analysis of gene perturbation at the cellular level can help better characterize biological mechanisms of hepatotoxicity. …”
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A Generic AI-Based Technique for Assessing Student Performance in Conducting Online Virtual and Remote Controlled Laboratories by Ahmed M. Abd El-Haleem, Mohab Mohammed Eid, Mahmoud M. Elmesalawy, Hadeer A. Hassan Hosny

“…One of the most challenging tasks in designing such LLMS is how to assess a student’s performance while an experiment is being conducted and how stuttering students can be automatically detected while experimenting and providing the appropriate assistance. …”
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In Vitro Free Radical Scavenging Properties and Anti-Inflammatory Activity of Ilex paraguariensis (Maté) and the Ability of Its Major Chemical Markers to Inhibit the Production of... by Ingrid Vicente Farias, Eduarda Fratoni, Lais Cristina Theindl, Angela Machado de Campos, Eduardo Monguilhott Dalmarco, Flavio Henrique Reginatto

“…Furthermore, TNF-α secretion was also significantly decreased by THEO at 0.033 μM (22.15±6.49%), NCA at 1.97 μM (27.46±3.98%), CCA at 0.35 μM (39.76±5.73%), CGA at 0.56 μM (23.58±5.79%), CAF at 0.52 μM (26.45±5.34%), and RUT at 0.16 μM (40.18±3.70%). …”
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Past Obesity as well as Present Body Weight Status Is a Risk Factor for Diabetic Nephropathy by Shu Meguro, Yusuke Kabeya, Karin Tanaka, Toshihide Kawai, Masuomi Tomita, Takeshi Katsuki, Yoichi Oikawa, Yoshihito Atsumi, Akira Shimada, Masami Tanaka, Junichiro Irie, Yoshifumi Saisho, Hiroshi Itoh

“…The prevalence of nephropathy was significantly higher in subjects with current obesity (40.6%) or previous obesity (35.6%) than in those who were continuously lean (24.3%) (P<0.017). In logistic regression analysis, previous obesity, as well as current obesity, was a significant risk factor for nephropathy, independent of sex, age, disease duration, hypertension, dyslipidemia, HbA1c, and diabetic retinopathy. …”
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Geospatial distribution of Hepatitis E seroprevalence in Nepal, 2021. by Chulwoo Rhee, Amy Dighe, Nishan Katuwal, Haeun Cho, Ramzi Mraidi, Dipesh Tamrakar, Jacqueline KyungAh Lim, Nimesh Poudyal, Il-Yeon Park, Deok Ryun Kim, Ritu Amatya, Rajeev Shrestha, Andrew S Azman, Julia Lynch

“…Seroprevalence in hilly (28.9%, 95% CI: 26.6-31.2) and mountain (24.6%, 95% CI: 18.8-30.5) regions were significantly higher than in terai (14.2%, 95% CI: 12.7-15.8). …”
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The dynamic characteristics of the shearer cable drag system. by Bo Xie, Feida Wang, Jing Liu, Zhanjun Xu, Shuaishuai Gao, Lijuan Zhao

“…These values are significantly lower than the cable clamp's breaking tensile strength of 70 kN, with peak values of 57.4 N and 94.1 N, respectively. During the cable bending process, The contact force with the cable clamp continuously changes with the bending angle, During 0 ~90°, the contact force between ordinary and reinforced cable and cable clamp gradually increases to the maximum values 61.3N and 86.2N, After 90 have plummeted to near 23 N and 25 N, In the process of dragging the cable to the top of the roller, it fluctuates between 45.2~51.7 N and 66.3~73.6 N respectively, Cable exit bends are slowly reduced to fluctuations around 16 N and 17 N, The tensile force between ordinary and reinforced discrete cables increased to around 58.4 N and 80.5 N and then decreased to around 12.6 N and 32.8 N, respectively. …”
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Graph pangenome reveals the regulation of malate content in blood-fleshed peach by NAC transcription factors by Wenbo Chen, Qi Xie, Jia Fu, Shaojia Li, Yanna Shi, Jiao Lu, Yuanyuan Zhang, Yingjie Zhao, Ruijuan Ma, Baijun Li, Bo Zhang, Donald Grierson, Mingliang Yu, Zhangjun Fei, Kunsong Chen

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Serum Inflammatory Cytokines and Growth Factors in Patients with Sjögren’s Syndrome and Diabetes Mellitus by Yalçın Karaküçük, Sema Yilmaz, Ali Unlu, Banu Bozkurt, Şule Nur Acar Duyan

“…Serum insulin-like growth factor 1 (IGF-1) level was lowest in DM patients (DM: 12.89±21.09, SS: 30.77±19.85, and control: 27.08±21.93 ng/mL) (p&lt;0.05). …”
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Sex and gender differentials in the prevalence of obesity and its association with multimorbidity among reproductive-aged individuals in India by Jogesh Murmu, Abhinav Sinha, Ritik Agrawal, Bhagyashree Rout, Srikanta Kanungo, Sanghamitra Pati

“…Males with multimorbidity had a 47% higher likelihood of having obesity (AOR: 1.47, 95% CI: 1.13–1.89, p &lt; 0.003) compared to individuals without obesity.ConclusionThe study highlights high obesity prevalence among reproductive-aged individuals in India, with females having higher obesity rates overall. …”
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Lenvatinib versus sorafenib as second-line therapy following progression on atezolizumab–bevacizumab in patients with unresectable hepatocellular carcinoma: a multicenter retrospec... by Jaekyung Cheon, Shigeo Shimose, Hyung-Don Kim, Takashi Niizeki, Min-Hee Ryu, Tomotake Shirono, Baek-Yeol Ryoo, Hideki Iwamoto, Changhoon Yoo

“…After PSM, in a cohort of 50 patients (25 per each group), LEN maintained its PFS advantage over SOR (median 4.8 vs. 3.3 months, p = 0.046), while the median OS was longer with LEN but not statistically different (median 11.4 vs. 7.9 months, p = 0.197). Response rates were 40% for LEN and 12% for SOR (p = 0.021) based on modified RECIST, and 12% and 8% (p = 0.728) based on RECIST v1.1, respectively. …”
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Healthcare-seeking delays and associated factors among immigrant patients with acute ischaemic stroke in Shenzhen: a retrospective observational study by Qingshi Zhao, Changyu Li, Zongbi Wu, Youli Jiang, Yanfeng Li

“…The study investigated sociodemographic, clinical data and stroke-specific scales (modified Rankin Scale, National Institutes of Health Stroke Scale, Glasgow Coma Scale) to identify factors influencing delays.Setting The study was conducted in Shenzhen, a city characterised by a significant immigrant population, providing insights applicable to urban regions with similar demographics.Results Of the 1356 patients studied, 82.6% (n=1120) experienced healthcare-seeking delays, with a median delay of 12.67 hours (IQR: 3.5–28.8). Factors associated with prolonged delays included lack of stroke awareness (92.96% delay rate), low educational attainment, self-transportation to the hospital (adjusted OR (aOR): 2.36, 95% CI: 1.57 to 3.54) and wake-up strokes (aOR: 4.37, 95% CI: 2.28 to 8.36). …”
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Postoperative Pain and Opiate Requirement is Increased Following Second-Side Surgery Among Patients Undergoing Staged Total Knee Arthroplasty by Vivek P. Chadayammuri, MD, Shuvalaxmi D. Haselton, MS, Elizabeth Diaz, PA-C, Roger H. Emerson, MD

“…Female patients were increasingly susceptible to elevated pain levels following second-side TKA (β = 0.372; P = .057). Conclusions: Postoperative pain increases after second-side TKA in staged-bilateral procedures, despite the more symptomatic side being addressed first. …”
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Effect of Different Doses of Sugammadex on Recovery and Hemodynamic Parameters in Reversing Neuromuscular Blockade in Patients Undergoing Electroconvulsive Therapy by Kadir ARSLAN, Gozde UCUKSARAC, Hale CETIN ARSLAN, Erkan AYDIN, Ayca Sultan SAHIN

“…While the average number of ECTs applied to the patients was 6.8+-2.8, the average seizure duration was 28.2+-12.7 seconds. The most common diagnosis (32.7%) in patients who underwent ECT was bipolar disorder. …”
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Clinical Characteristics of Metastatic Colorectal Cancer Combined with Gastrointestinal Perforation and Prognostic Value of Circulating Tumor DNA by Hong Yang, Dongwen Rong, Wenhui Yang

“…There were 56 cases (57.73%) with number of metastatic organs ≥2 and 41 cases (42.27%) <2. …”
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致心律失常性右室心肌病DSP基因突变与表现型的关系

“…【结果】 患者出现症状的时间为32.2 ± 12.7岁,男性患者的比例较高(85.0%),最常见的症状是心悸(82.5%),其次是胸痛(25.0%)和晕厥(22.5%)。…”
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Sedated and unsedated gastroscopy has no influence on the outcomes of patients with gastric cancer: a retrospective study by Chengke Yin, Yiwu Sun, Jie Liang, Xin Sui, Zhaoyi He, Ailing Song, Wenjia Xu, Lei Zhang, Yufei Sun, Jingshun Zhao, Fei Han

“…There was no significant difference in overall survival outcomes in the sedated gastroscopy group compared to the unsedated gastroscopy group before PSM (HR = 0.761, 95% CI: 0.531–1.091, P = 0.139) or after PSM (HR = 0.874, 95% CI: 0.564–1.355, P = 0.547). …”
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Protective Effects of N-Acetylcysteine in Concanavalin A-Induced Hepatitis in Mice by Chengfen Wang, Yujing Xia, Yuanyuan Zheng, Weiqi Dai, Fan Wang, Kan Chen, Jingjing Li, Sainan Li, Rong Zhu, Jing Yang, Qin Yin, Huawei Zhang, Junshan Wang, Jie Lu, Yingqun Zhou, Chuanyong Guo

“…Our results demonstrate that NAC can alleviate ConA-induced hepatitis by regulating the PI3K/Akt pathway and reducing the late stages of autophagy. …”
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Substitution of manure source and aerator in nursery media on sandy loam topsoil and their fertility indices 4 months after formulation by C. V. Adubasim, C. M. Igwenagu, G. O. Josiah, S. E. Obalum, U. M. Okonkwo, I. M. Uzoh, S. Sato

“…Reference surpassed topsoil+slurry+huskdust for Ca2+, but was surpassed by topsoil+droppings+huskdust for Mg2+. …”
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Edukacinio 3D virtualiosios realybės vaizdo metodo įtaka ruošiant žarnyną kolonoskopijai: pirmieji rezultatai by Edvinas Kildušis, Gintautas Brimas

“…Vidutinis (SD) BŽPS balas buvo statistiškai reikšmingai mažesnis kontrolinėje grupėje, palyginti su 3D-VR vaizdo įrašą stebėjusių tiriamųjų grupe (plg.: 5,96(±1) ir 7,58(±1,47); p < 0,001). Vidutiniai (SD) OŽPS balai buvo didesni kontrolinėje grupėje (6,58(±2,44), palyginti su tiriamąja grupe (1,83(±2,32); p < 0,001). …”
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