Novel thiazolyl-pyrimidine derivatives as potential anticancer agents: Synthesis, biological evaluation, and molecular docking studies by Tariq Z. Abolibda, Abdel-Aziz A.A. El-Sayed, Basant Farag, Magdi E.A. Zaki, Abdulwahed Alrehaily, Hossein M. Elbadawy, Ahmad A. Al-Shahri, Saleh R. Alsenani, Sobhi M. Gomha

“…Five compounds, namely 8a, 10, 12a, 12b, and 14, exhibited promising anticancer activity with IC50 values of 5.02 ± 1.83, 4.04 ± 1.37, 3.81 ± 1.96, 2.39 ± 0.75, and 3.27 ± 1.13 μM, respectively, all of which were more effective than doxorubicin (IC50 = 6.18 ± 0.29 μM). …”
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Automatic Segmentation of Abdominal Aortic Aneurysm From Computed Tomography Angiography Using a Patch-Based Dilated UNet Model by Merjulah Roby, Juan C. Restrepo, Haehwan Park, Satish C. Muluk, Mark K. Eskandari, Seungik Baek, Ender A. Finol

“…Abdominal Aortic Aneurysm (AAA) is still a socially relevant public health challenge, evidenced by an 82.1% increase in associated fatalities from 1990 to 2019 (with 172,427 deaths in 2019 alone). In a clinical setting, computed tomography angiography (CTA) is the imaging modality of choice for monitoring and/or presurgical planning of AAA patients. …”
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Cross-sectional study of cybervictimisation and non-suicidal self-injury among college students in China: a chain mediation effect of emotion dysregulation and social exclusion by Juan Ni, Xiaoli Liao, Liu Xine

“…Multivariate regression analysis identified significant predictors of NSSI behaviours, including gender (β=0.06, p<0.05), being a left-behind child (β=−0.20, p<0.05), being the only child (β=0.07, p<0.05), cybervictimisation (β=0.32, p<0.001), emotion dysregulation (β=0.41, p<0.001) and social exclusion (β=0.15, p<0.001). …”
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Antimicrobial Susceptibility of <i>Salmonella typhi</i> and <i>paratyphi</i> among Pediatric Population at Tertiary Care Center of North Delhi: A Retrospective Study by Shekhar Biswas, Sulagna Tripathy, Arvind Kumar, Sanjay Chattree

“…Effective mass vaccination strategy against typhoid and water and safe hygiene (WASH) practices can decrease the burden of this disease. Broad-spectrum vaccine to cover both <i>S. typhi</i> and <i>S. paratyphi</i> is need of the hour.…”
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Second-line drug-resistant TB and associated risk factors in Karakalpakstan, Uzbekistan by S. Moe, I. Azamat, S. Allamuratova, M. Oluya, A. Khristusev, M.L. Rekart, K. Mamitova, G. Bidwell, C. Gomez-Restrepo, B. Kalmuratov, Z. Tigay, N. Parpieva, K. Safaev, N. Sitali, D. Gomez, A. Mikhail, A. Sinha

“…RESULTS: In total, 2,405 patients with TB who had undergone pDST were included (median age 40 years, 47% female). The overall SLDR-TB resistance rate was 24% (95% CI 22–26). …”
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Prevalence of Frailty Indicators and Association with Socioeconomic Status in Middle-Aged and Older Adults in a Swiss Region with Universal Health Insurance Coverage: A Population-... by Idris Guessous, Jean-Christophe Luthi, Christopher Barrett Bowling, Jean-Marc Theler, Fred Paccaud, Jean-Michel Gaspoz, William McClellan

“…Among middle-aged participants (50–65 years), 75.1%, 22.2%, and 2.7% presented 0, 1, and 2 or more frailty indicators. …”
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Segmentation of the iliac crest from CT-data for virtual surgical planning of facial reconstruction surgery using deep learning by Stefan Raith, Tobias Pankert, Jônatas de Souza Nascimento, Srikrishna Jaganathan, Florian Peters, Mathias Wien, Frank Hölzle, Ali Modabber

“…Quantitative evaluation of the correspondence yielded values for geometric agreement in the transplant-relevant area of 92% +/- 7% (Dice coefficient) and average surface deviations of 0.605 +/- 0.41 mm. …”
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Determinants of Work-Related Risks among Veterinary Clinical Students in South West Nigeria by Oluwawemimo O. Adebowale, Monsurat O. Afolabi, Hezekiah K. Adesokan, Olubunmi G. Fasanmi, Olanike K. Adeyemo, Olajoju J. Awoyomi, Folorunso O. Fasina

“…Data on demographics, health and safety (HS) status, work-related hazards, healthcare facilities, and immunisation history were obtained. Of 167 students recruited, 100 (60.2%) were males, and >77.1% fell within the age group of 21–25 years. …”
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Comparison of Self-Efficacy and Knowledge of Human Papillomavirus Vaccination among Various Types of Decision Makers in Indonesia: A Cross-Sectional Study by Dora Samaria, Eva Tallutondok, Chandrayani Simanjorang, Imanuel Imanuel

“…Background: Self-efficacy and knowledge of various types of decision-makers concerning the Human Papillomavirus (HPV) vaccine can play an essential role in the acceptance of the vaccine in women. …”
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The impact of the COVID-19 pandemic on time to treatment in head and neck cancer management: a systematic review by Malte Grumstrup Simonsen, Amanda-Louise Fenger Carlander, Kathrine Kronberg Jakobsen, Christian Grønhøj, Christian von Buchwald

“…No changes in treatment modalities were observed. Seven of 15 studies (12.7% of the patients) observed an increase in either overall stage, size, or tumor node and metastasis classification during the COVID-19 pandemic. …”
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Investigation on Mechanical Properties and Reaction Characteristics of Al-PTFE Composites with Different Al Particle Size by Jia-xiang Wu, Xiang Fang, Zhen-ru Gao, Huai-xi Wang, Jun-yi Huang, Shuang-zhang Wu, Yu-chun Li

“…The toughness rose firstly and subsequently decreased and peaked as 116.42 MJ/m3 at 6∼7 μm. The reaction phenomenon occurred only in composites with the Al particle size less than 10 μm. …”
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Abnormal expression of miR-668-3p in non-small cell lung cancer patients and its correlation with serum-related tumor markers by Wen Yang, Ling Liu, Jianliang Li, Yingchao Liu, Lin Rong, Junjie Ma, Rongchen Li, Qiuyue Zhang, Yugang Liu

“…The association between miR-668-3p and clinical characteristics and serum biomarker (AFP, CEA, NSE, and CYFRA21-1) levels in NSCLC patients was examined using chi-square tests and Pearson correlation analyses. …”
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Right ventricular function in athletes engaged in endurance exercise using speckle tracking echocardiography: a meta-analysis by Chenzan Guo, Hebin Zhang, Cunxin Yang, Peipei Hu, Hui Ma, Ying Ma, Feng Gao

“…A fixed effect meta-analysis revealed RV global longitudinal strain (GLS) WMD = 0.40, 95% CI (-0.08 ~ 0.89), p = 0.102 and free wall longitudinal strain (FWLS) WMD = 0.62, 95% CI (0.28 ~ 0.96), p < 0.001, random effect models of RV basal strain WMD = 2.94, 95% CI (2.00 ~ 3.88), p < 0.001 and RV apical strain WMD = -0.79, 95% CI (-1.95, 0.37), p = 0.245 between endurance athletes and controls. …”
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Faster intervals, faster recoveries - intensified short VO2max running intervals are inferior to traditional long intervals in terms of time spent above 90% VO2max by Daniel Fleckenstein, Hannes Braunstein, Nico Walter

“…To analyze differences between the interval sessions, the paired t-test respectively the Wilcoxon test, if data were not normally distributed, were applied.ResultsThe time spent above 90% VO2max was significantly lower in the 30-s intervals, despite the higher intensity, compared to the 3-min session (201.3 ± 268.4 s vs. 327.9 ± 146.8 s, p = 0.05, r = 0.57). In contrast, the time spent above 90% HRmax was significantly higher for the 30-s intervals than for the 3-min intervals (820 ± 249 s vs. 545 ± 131 s, p &lt; 0.001, d = 1.73). …”
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Cardiovascular disease and its risk factors among people living with HIV: A systematic review and meta-analysis by Min Du, Shimo Zhang, Min Liu, Jue Liu

“…The pooled incidence rate of CVD was 6.31 per 1000 person-years. Among the 14 risk factors analyzed, the most prevalent was a history of CVD (odds ratio [OR]=3.47), followed by age (per 10-year increase) (OR=1.79), current smoking (OR=1.76), hypertension (OR=1.57), smoking (OR=1.53), diabetes (OR=1.50), previous smoking (OR=1.30), and hepatitis C virus (HCV) infection (OR=1.18). …”
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A Low Complexity Dual-Phase Alternating Scheme is Used With the PTS Method to Reduce PAPR for B5G Systems by Yung-Ping Tu, Chen-Wei Hsu

“…In the UFMC example, when the complementary cumulative distribution function (CCDF) is <inline-formula> <tex-math notation="LaTeX">$10^{-4}$ </tex-math></inline-formula>, compared with the original waveform, the PTS scheme, and the SLM scheme, the PAPR performance of the proposed scheme is improved by about 2.74, 1.87, and 0.35 dB respectively. Of course, our proposed method&#x2019;s bit error rate (BER) consistently outperforms the original waveform due to a valid PAPR reduction that weakens nonlinear distortion from the power amplifier.…”
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Preventive and curative dental services utilization among children aged 12 years and younger in Tehran, Iran, based on the Andersen behavioral model: A generalized structural equat... by Elaheh Amirian, Samaneh Razeghi, Alireza Molaei, Ahmad R Shamshiri, Simin Z Mohebbi

“…Among children aged 6 years and younger, age (OR = 1.87, p-value <0.001) and parent-perceived oral health need (OR = 54.77, p-value <0.001) predicted curative services utilization and age (OR = 1.45, p-value <0.001), knowledge (OR = 1.36, p-value <0.001), dental visit before the age of one (OR = 6.05, p-value = 0.04), and socioeconomic status (OR = 1.65, p-value = 0.03) predicted preventive/consultation services utilization. …”
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“I lock myself in my room and cry in frustration”: an analysis of adolescent behaviors of child-to-parent violence by Shirley Arias-Rivera, Barbara Lorence, Barbara Lorence, Jesus Maya

“…Among them, 410 adolescents (41.91% boys and 57.84% girls) reported engaging in some form of CPV behavior in the past year, and 47 adolescents met the criteria for severe and repeated CPV. …”
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Exploring the influence of age on the causes of death in advanced nasopharyngeal carcinoma patients undergoing chemoradiotherapy using machine learning methods by Mengni Zhang, Shipeng Zhang, Xudong Ao, Lisha Liu, Shunlin Peng

“…After IPTW, the older group was associated with worse 5-, 10-, and 15-year cumulative incidences in terms of NPC-related deaths (30, 34, and 38% vs. 21, 27, and 30%; P < 0.001), cardiovascular disease (CVD; 4.1, 7.2, and 8.8% vs. 0.5, 1.8, and 3.0%; P < 0.001), and other causes (8.3, 17, and 24% vs. 4.1, 8.7, and 12%; P < 0.001). …”
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ارزیابی تغییرات مکانی-زمانی کاربری اراضی بر اساس شاخص‌های کیفی اکولوژیکی (مطالعه موردی: حوضه دریاچه زریبار)... by مهین ساعدپناه, جمیل امان اللهی

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