右旋美托咪啶对大鼠脑缺血再灌注损伤的保护作用及机制

“…【结果】 再灌注２４ｈ后，脑梗死体积的比较显示Ｄｅｘ组（１７ ± ２．８）％较Ｄｅｘ＋Ｙｏｈ组（３８ ± ４．９）％与Ｃｏｎ组（４２ ± ５．７）％明显减小（Ｐ ＜ ０．０５），水肿指数比较显示Ｄｅｘ组（１．０２１ ± ０．０９８）较Ｄｅｘ＋Ｙｏｈ组（１．３４２ ± ０．１３７）与Ｃｏｎ组（１．４１７ ± ０．１０５）显著降低，差异有统计学意义（Ｐ ＜ ０．０５）。…”
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Blood Pressure and Haematological Indices in Twelve Communities in Ashanti, Ghana by Jacob Plange-Rhule, Sally M. Kerry, John B. Eastwood, Frank B. Micah, Sampson Antwi, Francesco P. Cappuccio

“…Mean values for Hb (12.3 g/dl ± 1.7 SD), haematocrit (36.7%±5.2), RBC (4.10 million/μL ± 0.64), and MCV were lower than reference values used in Sub-Saharan Africa. …”
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Nutritional and Microbiome Effects of a Partial Substitution of Poultry Meat with Hydrolyzed Feather Meal in Dog Diets by Fatemeh Balouei, Bruno Stefanon, Rosangela Armone, Andrea Randazzo, Biagina Chiofalo

“…The beta diversity between sexes was significantly different (<i>p</i>-value = 0.047). Linear Discriminant analysis effect size analysis revealed significant differences between dietary groups, identifying <i>Clostridiales</i>, <i>Coprococcus</i>, <i>Bacteroides plebeius</i>, <i>Eubacterium biforme</i>, <i>Catenibacterium</i>, and <i>Prevotella copri</i> as more abundant in the CTR diet, while <i>Fusobacterium, Bacteroides, Fusobacteriaceae</i>, <i>Paraprevotellaceae, Enterococcus</i>, <i>Faecalibacterium</i>, <i>Enterobacteriaceae</i>, <i>Peptostreptococcaceae</i>, and <i>Clostridium spiroforme</i> were more abundant in the treated diet. …”
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Elucidating the molecular basis of salt tolerance in potatoes through miRNA expression and phenotypic analysis by Caicai Lin, Shuangshuang Zheng, Kui Liu, Ru Yu, Peiyan Guan, Baigeng Hu, Lingling Jiang, Mengyu Su, Guodong Hu, Qingshuai Chen, Xia Zhang

“…This study evaluated the salt tolerance of 17 diverse potato varieties using principal component analysis, membership function analysis, cluster analysis, and stepwise regression analysis. …”
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考虑杆件缺陷的双层焊接球柱面网壳稳定性研究(英文) by 肖姚, 李会军, 韩健

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Relationship between physical activity and depressive symptoms in stroke survivors: a cross-sectional study of 1,140 individuals by Yihao Wang, Jiali Chen, Yanwei Zou, Mengshu Yang, Xiaoyun Kong, Ling Wang, Jingyuan Xue, Ci Dong

“…If vigorous-intensity PA duration is longer than 75 min (odds ratio [OR] = 0.41, 95% CI 0.21–0.75) or longer than 150 min (OR = 0.42, 95% CI 0.19–0.85), and moderate-intensity physical activity duration is longer than 150 min (OR = 0.59, 95% CI 0.38–0.90) or between 150 and 300 min (OR = 0.36, 95% CI 0.15–0.77), and moderate-to-vigorous PA duration is greater than 150 min (OR = 0.61, 95% CI 0.40–0.91) or exceeding 300 min (OR = 0.50, 95% CI 0.31–0.78), this might be associated with lower depressive symptoms. …”
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Experiences of community-dwelling older adults living with multiple chronic conditions: a qualitative study by Sharon Kaasalainen, Jenny Ploeg, Marta Canesi, Kimberly D Fraser, Carrie McAiney, Maureen Markle-Reid, Sinead Dufour, Lisa Garland Baird, Tracey Chambers

“…Objectives The aim of the study was to understand the experiences of living with multiple chronic conditions (MCC) from the perspective of community-living older adults with MCC.Design A qualitative study using an interpretive description approach.Setting Participants were recruited from southern Ontario, Canada.Participants 21 community-living, older adults (≥65 years) with an average of 7.4 chronic conditions including one of diabetes, dementia or stroke.Methods Data were collected through digitally-recorded, in-depth, semi-structured in-person interviews. …”
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Postoperative Outcomes in Prepectoral Versus Retropectoral Immediate Implant-based Breast Reconstruction Across Body Mass Index Categories by Gauthier Zinner, MS, Jérôme Martineau, MD, Giang Thanh Lam, MD, Daniel Correia, MS, Daniel F. Kalbermatten, MD, PhD, Carlo M. Oranges, MD, PhD

“…Preoperative characteristics, BMI, type of mastectomy procedure, PP or RR implant placement, and postoperative outcomes were collected and analyzed. Results:. A total of 217 patients were included, representing 276 IBBRs. …”
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Thermogenic Effect of Glucose in Hypothyroid Subjects by Agnieszka Kozacz, Paulina Grunt, Marta Steczkowska, Tomasz Mikulski, Jan Dąbrowski, Monika Górecka, Urszula Sanocka, Andrzej Wojciech Ziemba

“…It was found that TEG was lower in hypothyroid than in control group (19.68±3.90 versus 55.40±7.32 kJ, resp., P<0.0004). Mean values of glucose and insulin areas under the curve were higher in women with hypothyroidism than in control group (286.79±23.65 versus 188.41±15.84 mmol/L·min, P<0.003 and 7563.27±863.65 versus 4987.72±583.88 mU/L·min, P<0.03 resp.). …”
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Aprovechamiento de lanche, hierbaluisa y stevia en la elaboración de infusiones by Edson Elvis Ramirez-Tixe, Faustino Ruiz-Díaz, Josué Miler Herrera-Oblitas, Yaneth Cubas-Díaz, Hugo César Tocas-Burga

“…Se encontró asociación (R2 = 0,72) entre tiempo de infusión y sólidos solubles totales, porcentaje de hierbaluisa y parámetro b* (R2 = 0,77). El tratamiento T7 (30% de hierbaluisa, 55% de lanché y 15% de stevia, tiempo de infusión 244 s.) tuvo la mayor aceptabilidad sensorial en los atributos de olor, color, sabor y dulzor. …”
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Comparing the Fiscal Consequences of Controlled and Uncontrolled Osteoarthritis Pain Applying a UK Public Economic Perspective by Rui Martins, Nikos Kotsopoulos, Melodi Kosaner Kließ, Craig Beck, Lucy Abraham, Samuel Large, Patricia Schepman, Mark P. Connolly

“…**Background:** Individuals experiencing osteoarthritis (OA) pain can pose significant costs for governments due to reduced work activity in these individuals and increasing reliance on public support benefits. …”
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An integrated protocol based on workflows of imaged capillary isoelectric focusing (icIEF) for in-depth protein heterogenous characterization: High-efficient fractionation and onli... by Teresa Kwok, She Lin Chan, Mike Zhou, Tong Chen, Niusheng Xu, Victor Li, Tiemin Huang, Tao Bo

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Hypothalamic atrophy in primary lateral sclerosis, assessed by convolutional neural network-based automatic segmentation by Jan Kassubek, Francesco Roselli, Simon Witzel, Johannes Dorst, Albert C. Ludolph, Volker Rasche, Ina Vernikouskaya, Hans-Peter Müller

“…Recently, we have introduced automatic hypothalamic quantification method based on the use of convolutional neural network (CNN) to reduce human variability and enhance analysis robustness. …”
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Poly-L-Arginine Induces Apoptosis of NCI-H292 Cells via ERK1/2 Signaling Pathway by Ya-Ni Wang, Ling-Ling Zhang, Xiao-Yun Fan, Sha-Sha Wu, Sheng-Quan Zhang

“…The expressions of the phosphorylation of extracellular signal-regulated kinase 1/2 (ERK1/2), Bcl-2/Bax, and cleaved caspase-3 were assessed by western blot. Results. PLA can induce apoptosis in NCI-H292 cells in a concentration-dependent manner. …”
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Cognitive trajectories and their relationships with education and diets among older adults: a network-based 10-year cohort study by Xuchun Wang, Yuchao Qiao, Yudong Zhang, Yu Cui, Hao Ren, Chongqi Hao, Lixia Qiu

“…After controlling for potential confounders, education and dietary-related variables were associated with a cognitive stable decline trajectory (OR: 0.857/0.929/1.027) and a cognitive rapid decline trajectory (OR: 0.859/0.914, 95% CI: 0.775–0.882) compared to the cognitive stable trajectory. …”
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Help-seeking behaviors among survivors of intimate partner violence during pregnancy in 54 low- and middle-income countries: evidence from Demographic and Health Survey data by Mariella Stiller, Michael Lowery Wilson, Till Bärnighausen, Adebola Adedimeji, Erin Lewis, Anne Abio

“…Methods This study made use of population-based data from the Demographic and Health Surveys (DHS) Program from 54 LMICs, collected between 2005 and 2020 (N = 359,027). Applying bivariate and multivariable analyses, the present study examined IPV survivors’ help-seeking distributions and associations with individual, partner, family, and community factors. …”
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Spatial variation and determinants of skilled birth attendant delivery among women of reproductive age in Ethiopia: a spatial and multilevel analysis by Yibeltal Addis Mekuria, Betelhem Gelaw Zeleke, Getahun Workineh Mekonen, Tewabe Malede Chekol

“…ArcGIS version 10.7 was used to visualize the geographic variations, and Kulldorff’s SaTScan version 9.6 was used to identify significant purely spatial clusters. …”
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Dynamics of blackleg epizootic process in the Republic of Kazakhstan by A. Abutalip, B. D. Aitzhanov, A. K. Mussayeva, V. Yu. Sushchikh, N. N. Yegorova, Ye. K. Ospanov, M. A. Berdikulov, K. A. Kalkabayev, N. Matikhan

“…Among all the diseases blackleg accounted for 20.7% (421 outbreaks), which suggests that the nosological unit is of high epizootological significance among other infectious animal diseases in the country. …”
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A case report: interstitial pneumonia following treatment of gastric cancer with sintilimab in combination with S-1 by Pei Zhu, Qingming Sun, Sheng Xu, Wanhui Dong

“…Severe interstitial pneumonia can lead to death. Antitumor drugs can induce interstitial pneumonia. …”
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جنبه‌های سینوپتیک و دینامیک طوفان برف با کولاک گسترده در ایران-14 تا20 بهمن 1350 by مهدی صداقت, حمید نظری پور, علیرضا صادقی نیا

“…یافته­ها بیانگر حاکمیت الگوی جوی بلاکینک از نوع رکس در دو فاز جداگانه از 3 تا 6 فوریه و از 7 تا 9 فوریه بوده است. تاوه قطبی در تزریق هوای سرد به عرض­های جغرافیایی پایین‌تر و کاهش محسوس دما پیش از رخداد طوفان برف و کولاک کاملاً تأثیرگذار بوده است. …”
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