A systematic screening assay identifies efficient small guide RNAs for CRISPR activation by Elin Arvidsson, Diana Duarte Lobo, Diana Duarte Lobo, Ermelinda Sabarese, Fabio Duarte, Rui Jorge Nobre, Rui Jorge Nobre, Rui Jorge Nobre, Luis Quintino, Cecilia Lundberg

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Impact of Sprouting Time of Chickpea on the Physicochemical, Textural, Sensory, and Total Phenolic Characteristics of Falafel Prepared from Sprouted Chickpea Flour by Kimia Goharpour, Fakhreddin Salehi, Amir Daraei Garmakhany

“…The finding of this research indicated that the sprouting process significantly increased the total phenolic content (from 284.17 to 720.98 μg gallic acid/g dry), antioxidant capacity (from 77.55% to 93.35%), and redness (from 7.65 to 11.39) of chickpea flour (p<0.05). …”
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The BLUP method in evaluation of breeding values of Russian spring wheat lines using micro- and macroelements in seeds by N. A. Potapova, A. S. Zlobin, I. N. Leonova, E. A. Salina, Y. A. Tsepilov

“…The following average values of the Pearson correlation were obtained for predicting the concentration of trace elements: K – 0.67, Ca – 0.61, Mg – 0.4, Mn – 0.5, Fe – 0.38, Zn – 0.46, Cu – 0.48. …”
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Calidad composicional y concentración de ácidos grasos omega-3 (alfa-linolénico) y omega-6 (linoleico) presentes en leche bovina de tres regiones naturales del Ecuador by D. C. Alvear, J. D. Guerrero, N. F. Bonifaz, P. F. Noriega

“…En cuanto al factor región, Costa presentó 2,07%, Sierra 3,03% y Amazonía 3,06%, por lo que se evidenció alta diferencia significativa (p ≤ 0,01) para el AL, mientras que el AAL no mostró variación. …”
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Comparison of remineralizing efficacy of two novel preparation of arginine and theobromine on white spot lesion - an in vitro SEM analysis by Shifo Savio F, Nivethigaa Balakrishnan, Aravind Kumar Subramanian

“…The arginine group increased significantly from 217.20 ± 4.24 to 304.00 ± 15.96, and the theobromine group from 214.09 ± 7.67 to 283.14 ± 10.91. …”
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Effect of Allium mongolicum Regel Powder Addition to the Diet and Aging Time on Physicochemical Properties and Antioxidant Capacity of Angus Beef by XIE Yaodi, GAO Huixia, HE Jianjian, SUN Chenxu, YU Aihuan, YAO Haibo, XU Lei, HU Jinsheng, WANG He, DUAN Yueyan, TANG Defu, LEI Zhaomin, LIU Wangjing

“…In this experiment, 24 healthy Angus cattle at (14 ± 2) months of age with similar body mass of (271.17 ± 17.6) kg were randomly divided into a control group and three experiment groups. …”
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Habilidades motoras fundamentales en preescolares chilenos by Paz Belén Fernández-Valero, Johana Soto-Sánchez

“…Los niños poseían mayores puntajes  p50 en las habilidades de locomoción, control de objetos (p = .007) y HMF total que las niñas. Niños y niñas mostraron mayores puntajes  p50 con el aumento de la edad en habilidades de locomoción (p = .002), control de objetos (p <.001) y HMF total (p <.001). …”
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Case study of natural convection topology optimization based on finite volume method by Honglei Liu, Shuzhe Guo, Ce Liu, Fei Du, Baotong Li, Jun Hong

“…This gap restricts applications of the natural convection topology optimization in common CFD software. This work presents an FVM-based topology optimization framework for natural convection, which is rare in previous studies. …”
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Predictive Value of Netrin-1 Expression and Ultrasonic Blood Flow in Cervical Intraepithelial Neoplasia Severity by Liu B, Wei L, Wu L, Wang H, Wang H, Yu Q

“…Bo Liu, Ling Wei, Lirui Wu, Huiying Wang, Hongli Wang, Qian Yu Department of Gynecology, Hebei Petro China Center Hospital, Langfang, People’s Republic of ChinaCorrespondence: Ling Wei, Email 74037604@qq.comObjective: To analyze the relationship and predictive value of Netrin-1 expression and ultrasonic blood flow parameters with the severity of cervical intraepithelial neoplasia (CIN).Methods: A retrospective analysis was performed on 115 patients diagnosed with CIN and 37 patients with chronic cervicitis, all of whom underwent surgical intervention. …”
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MHD Modeling of the Background Solar Wind in the Inner Heliosphere From 0.1 to 5.5 AU: Comparison With In Situ Observations by Y. X. Wang, X. C. Guo, C. Wang, V. Florinski, F. Shen, H. Li, M. Blanc

“…Statistical analysis for Year 2007 reveals that our model can predict most of the corotation interaction regions, high‐speed streams, and magnetic sector boundaries at 1 AU. …”
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IMPROVEMENT OF OIL PRODUCTION BY MATRIX ACIDIZING OF A WELL IN SANDSTONE RESERVOIR by Darel Sontia Fouazong, Isidore Komofor Ngongiah, André Chéagé Chamgoué, Alain Francis Talla, Jean Jacques Dikongue Jemea

“…The assessment of the X102 well indicates that it exhibited initial productivity from the natural energy of the oil reservoir, demonstrating an oil flow rate of 307 barrels per day with a skin value of 35. After 3 years of production, the X102 well experienced a decline in productivity due to fines migration. …”
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Assessment of long-term changes in subvalvular aortic stenosis in patients following transcatheter aortic valve implantation by Vladlen V. Bazylev, Andrey B. Voevodin, Alexey S. Masyutin

“…Pre- and postoperative median IVS thicknesses were 17.7±2.2 and 14.4±3.2 mm, respectively. Long-term outcomes of TAVI included a significant decrease in hypertrophy of IVS (p=0.031) IVS thicknesses mainly decreased over the period up to 24 months after surgery. …”
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Urological, vascular, and infectious implications of kidney transplant: a single-center experience by Juan G. Prada, Sofía Manjarrés-Sierra, Isabella Lince-Rivera, Carolina Martínez-Pinedo, Carolina Martínez-Pinedo, Germán Patiño, Hugo E. López

“…The most common chronic kidney disease etiologies were: idiopathic (25.5%), glomerulopathies (24.7%), and hypertension (23.5%). Seventy patients (28.8%) presented a complication, of which 31 were urological, 27 were infectious, and 12 were vascular. …”
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Biomarkers to predict the outcomes of surgical intervention for aortic dissection by Abanob G. Hanna, Fabian Jimenez Contreras, Omar M. Sharaf, Griffin P. Stinson, Philip J. Hess

“…The areas under the curve (AUCs) for the specified IL-6 and D-dimer cutoff values were 0.901 and 0.817, respectively, whereas the AUC reached 0.936 when IL-6 was combined with D-dimer. …”
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The Effect of Autologous Dendritic Cell Immunotherapy on Kidney Function and Endothelial Dysfunction of Patients with Diabetic Kidney Disease (DKD): An Open Label Clinical Trial by Martina Lily Yana, Enda Cindylosa Sitepu, Jonny, Linda Chiuman, I Nyoman Ehrich Lister, Terawan Agus Putranto

“…GFR did not show any significant changes after immunotherapy. HbA1c (B = −33.270, <i>p</i> = 0.021) and baseline UACR (B = −0.185, <i>p</i> < 0.001) were identified as significant predictors of UACR change. …”
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Characterizing the early relationship between covert narcissism and cognitive empathy in medical students: a cross-sectional study by Adelina Alcorta-Garza, Oscar Vidal-Gutiérrez, Juan F. González-Guerrero, Fernando Alcorta-Núñez, Guillermo A. Porras Garza, Montserrat San-Martín, Roberto C. Delgado Bolton, Luis Vivanco

“…Results In a sample of 283 students (207 females), differences in cognitive empathy and covert narcissism were observed by gender (p < 0.001). …”
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Hamstring Activity Before and After Break-Point Angle Calculated By Smartphone Application During the Nordic Hamstring Exercise by Toshiaki Soga, Shota Yamaguchi, Takayuki Inami, Hiromi Saito, Nadaka Hakariya, Naoto Nakaichi, Sho Shinohara, Koki Sasabe, Hayato Nakamura, Teerapat Laddawong, Kei Akiyama, Norikazu Hirose

“…The BF EMG activity at 20-25° after BPA was significantly lower than the BF EMG activity at BPA ± 5° (d = 0.87, p = 0.011). # CONCLUSIONS To prevent the recurrence of hamstring injuries, it is important to incorporate knee flexion exercises that enhance BF EMG activity at 15-35° of knee flexion (0° indicates a fully extended knee). …”
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Diet-wide analyses for risk of colorectal cancer: prospective study of 12,251 incident cases among 542,778 women in the UK by Keren Papier, Kathryn E. Bradbury, Angela Balkwill, Isobel Barnes, Karl Smith-Byrne, Marc J. Gunter, Sonja I. Berndt, Loic Le Marchand, Anna H. Wu, Ulrike Peters, Valerie Beral, Timothy J. Key, Gillian K. Reeves

“…Alcohol (relative risk per 20 g/day=1.15, 95% confidence interval 1.09-1.20) and calcium (per 300 mg/day=0.83, 0.77–0.89) intakes had the strongest associations, followed by six dairy-related factors associated with calcium. …”
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Assessment of correlation of fatigue in patients of rheumatoid arthritis using bristol rheumatoid arthritis fatigue multidimensional questionnaire score with disease activity – An... by Harpreet Singh, Kusum Yadav, Ritu Sangwan

“…Results: Fatigue score (BRAF-MDQ) decreased from 19.28 ± 13.846 at baseline to 17.46 ± 13.56 at M1 and 13.27 ± 11.633 at M3, respectively (P < 0.001). …”
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Emergency Care for Suicidal Behavior Before and During the COVID-19 Pandemic in Two Hospitals in Bogotá: a Longitudinal Analysis by Gutiérrez-Dajud, Sasha Stefany, Pastran-Cortés, Ana María, Mendivelso, Fredy, Rodríguez-Bedoya, Ingrid Milena, Moreno-Gómez, Jairo Enrique, Muñoz-Tamayo, Rodrigo

“…Results: A total of 884 individuals were admitted for suicidal behavior during the study period (67% women, 66% young adults, 55% students, and 1.6% LGBTQ+ population). …”
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