血管紧张素- (1- 7)预处理减轻大鼠离体心脏缺血再灌注损伤 by 何建桂, 彭龙云, 廖新学, 高修仁, 麦炜颐, 张雪娇

“…【目的】 探讨较大剂量血管紧张素- (1- 7) 预处理对大鼠心肌缺血再灌注损伤的影响及其信号机制。【方法】48 只 SD 大鼠随机分为 4 组, 每组 12 只: 缺血再灌注对照组、血管紧张素- (1- 7)预处理组、血管紧张素- (1- 7)预处理加磷脂酰肌醇- 3 激酶( PI3K) 抑制剂 Wortmannin 处理组、Wortmannin 处理对照组, 观察较大剂量血管紧张素- (1- 7)预处理对大鼠离体缺血再灌注心脏左心室收缩压、冠状动脉流量、肌酸磷酸激酶和乳酸脱氢酶释放、心肌梗死范围以及心肌蛋白激酶 B( Akt) 、糖原合成酶激酶- 3β( GSK- 3β) 磷酸化的影响。…”
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Pruritus Features in Children with End-Stage Renal Disease Underwent Dialysis: A Cross-Sectional Study by Mehryar Mehrkash, Seyed-javad Golestaneh, Yahya Madihi, Fatemeh Paknazar, Mahdi Hadian, Mojtaba Akbari, Bahareh Abtahi-Naeini

“…Thirty ESRD patients with pruritus, including 23 males (76.7%) with a mean age of 11.7±3.64 years, were recruited. …”
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The Dynamics of Type 2 Diabetes Mellitus Prevalence and Management Rates among Rural Population in Henan Province, China by Xiaotian Liu, Ling Wang, Panpan Wang, Ruihua Liu, Kaili Yang, Xinling Qian, Jingjing Fan, Songcheng Yu, Yuqian Li, Chongjian Wang

“…Over 5.74 years of follow-up, the age-standardized prevalence, awareness, treatment, and control of T2DM increased from 6.18%, 44.41%, 34.39%, and 19.08% at baseline to 7.87%, 59.64%, 52.17%, and 26.52% at follow-up in total population, respectively. …”
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Effects of Steam Explosion Pretreatment on the Physicochemical Properties and Regulating Intestinal Flora of Polysaccharides from Hericium erinaceus Fruit Body Residues by Shuang CHEN, Liping LIU, Jie FENG, Jingsong ZHANG, Yan YANG, Di WU, Yanfang LIU, Qingbin GUO

“…Shipin gongye ke-ji…”
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Effect of structural parameters of active pre-chamber on ammonia/hydrogen premixed combustion process: A numerical investigation by Zhe Kang, Da Peng, Jing Luo, Yang Lv, Lan Li

“…Under this scheme, numerical calculations show an optimum thermal efficiency of 47.93 %. This study also revealed the interaction mechanism between structural parameters of active pre-chamber and the combustion process of ammonia/hydrogen mixture, which is significantly important for optimizing combustion processes and engine performance, and provides research references for the industrial utilization of ammonia-hydrogen combustion engines in passenger vehicles.…”
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Effectiveness of Breast Cancer Awareness Month (BCAM) Before and After the COVID-19 Pandemic: Google Trends Analysis by Majed Ramadan, Walaa Alshekhi, Doaa Aboalola, Siham Aouabdi, Haneen Alzahrani, Abrar Ashi, Rawiah Alsiary

“…Breast cancer searches decreased notably post-pandemic (p = 0.007), while mammogram searches declined but not significantly (p = 0.31). …”
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New insights into the stipitate hydnoid fungi Sarcodon, Hydnellum, and the formerly informally defined Neosarcodon, with emphasis on the edible species marketed in Southwest China by Di Wang, Hui Feng, Jie Zhou, Tian-Hai Liu, Zhi-Yuan Zhang, Ying-Yin Xu, Jie Tang, Wei-Hong Peng, Xiao-Lan He

“…Phylogenetic analyses also revealed an unexpected species diversity (17 phylogenetic species) of Sarcodon and Hydnellum in the markets; nine phylogenetic species of Sarcodon and eight of Hydnellum were uncovered from the samples collected in the markets. …”
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Expert consensus guidelines on management and best practices for tumor-infiltrating lymphocyte cell therapy by Sarah Nikiforow, John Haanen, Omid Hamid, Igor Puzanov, Rodabe Amaria, Amod Sarnaik, Marcus O Butler, Michael R Bishop, Allison Betof Warner, Adam J Schoenfeld, Krishna Komanduri

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Regional Elastic Properties of the Achilles Tendon Is Heterogeneously Influenced by Individual Muscle of the Gastrocnemius by Jiping Zhou, Jiafeng Yu, Chunlong Liu, Chunzhi Tang, Zhijie Zhang

“…The intraoperator ICC of the gastrocnemius muscle-Achilles tendon complex was 0.77 to 0.95, while the interoperator ICC was 0.76 to 0.94. …”
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Experimental investigation on fresh, hardened and durability characteristics of partially replaced E-waste plastic concrete: A sustainable concept with machine learning approaches by Md. Hamidul Islam, Zannatun Noor Prova, Md. Habibur Rahman Sobuz, Nusrat Jahan Nijum, Fahim Shahriyar Aditto

“…The specimens, evaluated at 300 °C, exhibited reductions in compressive strength by 15.26%–30.87 % and tensile strength by 10.52%–19.74 % for e-waste replacement levels of 10%–20 %, respectively. …”
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Penalized landmark supermodels (penLM) for dynamic prediction for time-to-event outcomes in high-dimensional data by Anya H. Fries, Eunji Choi, Summer S. Han

“…When evaluated using the proposed metrics, the penLM model developed using multi-source data ( $$\:\overline{AUC}_{w}\:$$ of 0.77 [95% confidence interval: 0.74–0.79]) outperformed those developed using single-source data ( $$\:\overline{AUC}_{w}\:$$ range: 0.50–0.74). …”
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Increased Body Mass Index during Therapy for Childhood Acute Lymphoblastic Leukemia: A Significant and Underestimated Complication by Helen C. Atkinson, Julie A. Marsh, Shoshana R. Rath, Rishi S. Kotecha, Hazel Gough, Mandy Taylor, Thomas Walwyn, Nicholas G. Gottardo, Catherine H. Cole, Catherine S. Choong

“…At diagnosis, the majority of patients (77.5%) were in the healthy weight category. During treatment, increases in BMI z-scores were greater for females than males; the prevalence of obesity increased from 10.3% to 44.8% (P<0.004) for females but remained relatively unchanged for males (9.8% to 13.7%, P=0.7). …”
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An Effect Study of Structural Jets on the Long Gamma-Ray Burst Formation Rate at Low Redshift by Qi Guo, Qi Tan, Benyun Shi

“…After correcting for the redshift evolution, the luminosity function can be expressed as $\psi ({L}_{0})\propto {L}_{0}^{-0.17\pm 0.01}$ for dim LGRBs and $\psi ({L}_{0})\propto {L}_{0}^{-1.36\pm 0.05}$ for bright LGRBs, and the formation rate at z < 1 shows an increase. …”
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LIMIAR AERÓBIO E ANAERÓBIO NA CORRIDA AQUÁTICA: COMPARAÇAO COM OS VALORES OBTIDOS NA CORRIDA EM PISTA by Benedito Sérgio Denadai, Roberta Rosas, Mara Lucy Dompietro Ruiz Denadai

“…A FC encontrada na DWR (LAer = 137,0 ± 10,5; LAn =151,2 ± 12,1) foi significantemente menor, quando comparada com a mesma FC obtida na C (LAer = 159,5 ± 13,6; LAn= 185,1 ± 9,4). …”
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Combination of Two‐Stage Continuous Feeding and Optimized Synthetic Medium Increases Lipid Production in Lipomyces starkeyi by Chih‐Chan Wu, Kenji Okano, Pijar Religia, Yuki Soma, Masatomo Takahashi, Yoshihiro Izumi, Takeshi Bamba, Kohsuke Honda

“…In the second stage, we optimized the molar C/N ratio in the feeding medium for lipid production and achieved high biomass (130 ± 5 g L−1), lipid titer (88 ± 6 g L−1), and lipid content (67% ± 2% of dry cellular weight). …”
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Deep gradient reinforcement learning for music improvisation in cloud computing framework by Fadwa Alrowais, Munya A. Arasi, Saud S. Alotaibi, Mohammed Alonazi, Radwa Marzouk, Ahmed S. Salama

“…PeerJ Computer Science…”
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Analysis of Postural Control in Patients Diagnosed with Unilateral Knee Osteoarthrosis and Its Relationship with the Risk of Falls by Robson Emiliano José de Freitas, Jaqueline Gleice Aparecida de Freitas, Carolina Pereira Vieira, Daniela Cristina Endres, Fábio Martins Inacio, Fernanda Grazielle da Silva Azevedo Nora

“…During postural control with eyes open and eyes closed, the G1 group showed greater displacement of the COP in the anteroposterior direction—COPAP (p=0.007)—and mediolateral direction—COPML (p=0.033)—when compared to the G2 group. …”
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Automated diagnosis and classification of metacarpal and phalangeal fractures using a convolutional neural network: a retrospective data analysis study by Michael Axenhus, Anna Wallin, Jonas Havela, Sara Severin, Ablikim Karahan, Max Gordon, Martin Magnéli

“…The model performed best in diagnosing transverse metacarpal fractures, AUC = 0.91, 100% sensitivity, 87% specificity, and tuft phalangeal fractures, AUC = 0.97, 100% sensitivity, 96% specificity. …”
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Analysis of the Synergistic Effect of Endophytic Bacteria and Metabolites on Yield in Soybean Roots Under Biochar with Nitrogen Fertilization by Hui Liu, Wanyu Dou, Wenlong Zhang, Yutao Li, Guoxin Shi, Lifang Fu, Lihong Wang

“…The appropriate application of nitrogen fertilizers and biochar to the soil is beneficial for soybean growth, and a combination of biochar and nitrogen can improve low-nitrogen fertilizer utilization efficiency. …”
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Development of a mental health-related structural stigma measurement framework in the healthcare system setting: A modified Delphi study. by Dristy Gurung, Bhawana Subedi, Brandon A Kohrt, Syed Shabab Wahid, Sauharda Rai, Graham Thornicroft, Petra C Gronholm

“…Round 2 (n = 53 panellists; 51% women, 8.3% PWLEs, and 56.6% from LMICs) involved ranking indicators through an online survey, and Round 3 (n = 58 panellists; 46% women, 21.7% PWLEs, and 60.4% from LMICs) involved re-ranking the results from Round 2. …”
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