Dual-modal radiomics ultrasound model to diagnose cervical lymph node metastases of differentiated thyroid carcinoma: a two-center study by Jiajia Tang, Yan Tian, Jiaojiao Ma, Xuehua Xi, Liangkai Wang, Zhe Sun, Xinyi Liu, Xuejiao Yu, Bo Zhang

“…The radiomics model displayed higher diagnostic ability than the traditional ultrasound model in the training set [0.871 (95% CI: 0.839–0.904) vs. 0.848 (95% CI: 0.812–0.884), p<0.01], internal test set [0.804 (95% CI: 0.741–0.867) vs. 0.803 (95% CI: 0.74–0.866), p = 0.696], and external validation cohort [0.939 (95% CI: 0.893–0.984) vs. 0.921 (95% CI: 0.857–0.985), p = 0.026]. …”
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PDL1 inhibitors may be associated with a lower risk of allograft rejection than PD1 and CTLA4 inhibitors: analysis of the WHO pharmacovigilance database by Alexandre O. Gérard, Alexandre O. Gérard, Alexandre O. Gérard, Diane Merino, Diane Merino, Jonathan Benzaquen, Alexandre Destere, Delphine Borchiellini, Clément Gosset, Clément Gosset, Fanny Rocher, Marine Andreani, Charles-Hugo Marquette, Henri Montaudié, Henri Montaudié, Milou-Daniel Drici, Antoine Sicard, Antoine Sicard

“…The comparative Reporting Odds Ratios (ROR) for AR, between PD1 and PDL1 inhibitors, was calculated.ResultsWe gathered 159 AR involving an ICI, especially nivolumab (73, 45.9%), mostly affecting kidneys (87, 54.7%). Median time to onset: 28 days. Fatal outcome: 36 reports (22.6%). …”
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Temporal Trends in Mortality and Hospitalization Risk in Patients With Heart Failure According to the Hospital Frailty Risk Score by Noor K. Abassi, Nina Nouhravesh, Mariam Elmegaard, Marte Austreim, Deewa Zahir, Caroline Hartwell Garred, Jawad H. Butt, Camilla Fuchs Andersen, Jarl E. Strange, Caroline Sindet‐Pedersen, Daniel M. Christensen, Emil Fosbøl, Charlotte Andersson, Lars Køber, Morten Schou

“…Methods and Results We identified 131 235 patients with new‐onset HF (median age 74 years, 39.7% women) from Danish nationwide registers in 1999 to 2017. …”
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Burden of brain and other central nervous system cancer in China, 1990–2019: a systematic analysis of observational data from the global burden of disease study 2019 by Peng Yin, Maigeng Zhou, Fan Zhang, E Wang, Xinran Hou, Zongbin Song, Zhuoyi Liu, Wenyong Long, Zheng Long, Maoen Zhu

“…Objective To evaluate the trends in disease burden and the epidemiological features of central nervous system (CNS) cancer in China from 1990 to 2019.Design A population-based observational study.Setting The incidence, prevalence, death and disability-adjusted life years (DALYs) due to CNS cancer in China, stratified by sex, age and provincial region, were collected from the Global Burden of Disease Study 2019.Participants Data were publicly available and individuals were not involved.Results In 2019, the incident cases of CNS cancer in China were 347 992 (95% UI 262 084–388 896), and the age-standardised rate (ASR) of incidence was 5.69 (95% UI 4.36–6.78) per 100 000 person-years increased by 27.9% compared with that in 1990; meanwhile, CNS cancer caused 63 527 (95% UI 47 793–76 948) deaths in China in 2019, and the ASR of death was 3.5 (95% UI 2.62–4.21) per 100 000 person-years decreased by 9.6%. …”
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Factors influencing the overall satisfaction of teachers participating in a nationwide school-based smoking prevention program in Korea by Geon Heo, Seulgi Kim, Sung-il Cho, Seunghyun Yoo, Jieun Hwang

“…Conversely, for high school teachers, the effectiveness (β=0.347; 95% CI: 0.184–0.520) was the variable that significantly improved overall satisfaction with the SSPP operation. …”
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Real-world outcomes of the CROSS regimen in patients with resectable esophageal or gastro-esophageal junction adenocarcinoma: a nationwide cohort study in the NetherlandsResearch i... by Hanneke van Laarhoven, Rob Verhoeven, Mark van Berge Henegouwen, Nadia Haj Mohammad, Richard van Hillegersberg, Marije Slingerland, Christina T. Muijs, Bas Wijnhoven, Bianca Mostert, Laurens Beerepoot, Grard Nieuwenhuijzen, Sarah Derks, Peter S.N. van Rossum

“…In the complete study population, the median overall survival (OS) was 33.7 months (95% CI 32.0–35.6), with a 3-year OS rate of 48.1%. …”
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Regional Arterial Stiffness in Patients with Inflammatory Bowel Disease by V. V. Genkel, R. G. Portnova, T. V. Antipina, I. I. Shaposhnik

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Prevalence, risk factors, and prognostic implications of intraoperative bleeding during CF-LVAD implant by Ibrahim Mortada, MD, Christos Kourek, MD, PhD, Rupesh Kshetri, MD, Arun Singhal, MD, Anthony Panos, MD, Alexandros Briasoulis, MD, PhD, Mohammed Mhanna, MD, MPH, Shareef Mansour, MD, Kristine Yumul, MD, Paulino Alvarez, MD, Ernesto Ruiz Duque, MD

“…Multilogistic regression analysis showed that artery bypass grafting pre-LVAD (odds ratio [OR] 2.98, confidence interval [CI] 1.2-7.42, p = 0.01) and temporary mechanical assist device pre-LVAD (OR 3.67, 95%CI 1.72-7.85, p < 0.001) were independent predictors of intraoperative bleeding during hospitalization. …”
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Impact of COVID-19 Control Measures on Trace Gases (NO2, HCHO and SO2) and Aerosols over India during Pre-monsoon of 2020 by Mriganka Sekhar Biswas, D. C. Ayantika

“…A reduction in NO2 was also seen over the top six populous Indian cities, with Mumbai recording the highest decrease (−33.7%). But only Chennai showed a substantial decrease (−6.8%) in HCHO. …”
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Larvicidal activity of Bacillus thuringiensis strains against Aedes aegypti and Culex quinquefasciatus mosquitoes by Prakai Rajchanuwong, Sawaporn Peaboon, Ratchadawan Ngoen-Klan, Atsalek Rattanawannee, Atirat Noosidum, Boonhiang Promdonkoy, Jariya Chanpaisaeng, Theeraphap Chareonviriyaphap

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Prevalence of Latent Tuberculosis Infection in the Middle East and North Africa: A Systematic Review by Mazin Barry

“…The overall prevalence was 41.78% (95% CI 31.18% to 52.78%, I2=99.31%). By gender-based subgroup analysis, the prevalence of LTBI was 33.12% (95% CI 18.97% to 49.04%, I2=99.25%) and 32.65% (95% CI 19.79% to 47%, I2=98.89%) in males and females, respectively, while in the age-based subgroup analysis, the prevalence of LTBI was 0.44% (95% CI -0.05% to 0.9%), 3.37% (95% CI 2.23% to 4.74%, I2=0%), and 43.81% (95% CI 33.09% to 54.82%, I2=99.18%) for children, adolescents, and adults, respectively. …”
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An assessment of compliance with proposed regulations to restrict on-package marketing of packaged foods to improve nutrition in South Africa by Safura Abdool Karim, Tamryn Frank, Alice S. Khan, Morongoa G. Tlhako, Sikhumbule K. Joni, Elizabeth C. Swart

“…A codebook was developed based on R337. The codebook was used to identify and assess child-directed marketing (CDM) and health claims on products potentially subject to front-of-package WLs. …”
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Efficacy and safety of FOLFIRI/aflibercept in second‐line treatment of metastatic colorectal cancer in a real‐world population: Prognostic and predictive markers by Ana Fernández Montes, Nieves Martínez Lago, Marta Covela Rúa, Juan de la Cámara Gómez, Paula González Villaroel, José Carlos Méndez Méndez, Mónica Jorge Fernández, Mercedes Salgado Fernández, Margarita Reboredo López, Guillermo Quintero Aldana, María Luz Pellón Augusto, Begoña Graña Suárez, Jesús García Gómez

“…Development of hypertension (any grade) was significantly associated with a reduced risk of progression by multivariate analysis (HR = 2.7; 95%CI 1.3‐5.4; P = 0.001). Conclusions Efficacy with FOLFIRI‐aflibercept in a real‐life population was in line with results from the pivotal trial and toxicity was manageable with treatment adaptation. …”
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An evidence-based tailored eHealth patient education tool for patients with knee osteoarthritis: A randomized controlled trial by Chong Li, Chuanmei Zhu, Kangping Song, Xiaona Xiang, Xiaoyi Wang, Jing Hu, Zhao Li, Yi Deng, Daoxin Jiang, Lixin Guo, Ting Ren, Luwen Zhu, Haibo Ai, Shaojun Zhang, Zhongliang Liu, Yonghong Yang, Siyi Zhu, Chengqi He

“…Results The results of the PKQ-OA indicated that patients in the eHealth group (38.7% ± 25%, 95% confidence interval (CI), 33.9%–43.4%) performed significantly better than the usual care group (28.8% ± 21.1%, 95% CI, 24.9%–32.9%) in terms of correct responses to the knowledge assessment in T1( P  = 0.001). …”
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Temporomandibular Joint Ankylosis among Patients at Saint Paul’s Hospital Millennium Medical College, Ethiopia: A 9-Year Retrospective Study by Dereje Mekonnen, Andamlak Gizaw, Bruktawit Kebede

“…Forty-two (44.2%) of the TMJA cases were males, while the remaining 53 (55.8%) were females with a male to female ratio of 0.79 : 1. 20–29-year-old patients were the most affected, 36 (37.9%), followed by the 30 to 39 years age group, 33 (34.7%). …”
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Adequate Reporting Among Ventral Hernia Repair Operative Reports: A Cross-Sectional Study of Prevalence of Details and Association With Clinical Outcomes by Said Maldonado, BS, Nicole B. Lyons, MD, Jonathan S. Lall, BS, J. Scott Zimmerle, MBA, Brendan Rosamond, BS, Ashlynn Mills, BS, Yoolim Alex Seo, BS, Angelica Calderon Rodriguez, BS, Rainna Coelho, MD, Natalia Cavagnaro, MD, Zuhair Ali, MD, Mike K. Liang, MD

“…Only 35.7% of operative reports were highly detailed. …”
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Retrospective Analysis of Ultrasound-Guided Infraclavicular Block: Effect of Experience of Anesthesiologists on Volume of Local Anesthetic Administered by Tugce Yeniocak, Nur Canbolat

“…The LA volume administered in group I (33.7 ± 4.2 ml) was significantly higher than that in groups II, III, and IV (p<0.05). …”
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Appropriate Blood Pressure in Cerebral Aneurysm Clipping for Prevention of Delayed Ischemic Neurologic Deficits by Cattleya Thongrong, Pornthep Kasemsiri, Pichayen Duangthongphon, Amnat Kitkhuandee

“…Data suggested that the optimal cutoff points for lowest blood pressure for prevention of DNID should be systolic blood pressure (SBP) of 95 mmHg (sensitivity of 78.6%; specificity of 53.6%), diastolic blood pressure (DBP) of 50 mmHg (sensitivity of 71.4%; specificity of 67.9%), and mean arterial pressure (MAP) of 61.7 mmHg (sensitivity of 85.7%; specificity of 35.7%). …”
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Cementless Metaphyseal Sleeve Fixation in Revision Knee Arthroplasty: Our Experience with an Arabic Population at the Midterm by Abdulrahman D. Algarni

“…One patient (3.7%) developed heterotopic ossification, and another one (3.7 %) had a stem-tip pain on the tibial side; both were managed conservatively. …”
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The diagnostic accuracy of circulating free DNA for the detection of KRAS mutation status in colorectal cancer: A meta‐analysis by Wenli Xie, Li Xie, Xianrang Song

Subjects: “…cfDNA…”
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