Smokeless, not harmless: Understanding Naswar's cardiovascular risks in the northwestern Pakistan by Ihsanur Rahman, Fayaz Ahmad, Naveed Sadiq

Subjects: “…Coronary artery disease (CAD)…”
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Enhanced Detection of Residual Breast Cancer Post-Excisional Biopsy: Comparative Analysis of Contrast-Enhanced MRI with and Without Diffusion-Weighted Imaging by Han Song Mun, Bong Joo Kang, Sung Hun Kim, Ga Eun Park

“…Sensitivities for MG and US were 57.1% and 38.7%, with NPVs of 64.7% and 59.6%, respectively. …”
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Airway Management in Pan Facial Fracture: An Outcome Analysis of Elective Tracheostomy and Submental Endotracheal Intubation by Vipin Venugopal Nair, Yuvraj Issar, Harmanjot Singh Dhillon, Gurpinder Singh Ghotra, Pranay Pratap, Ayush Mathur, Kamalpreet Singh

“…SEI consisted of 23 patients (60%) while ET had 15 (40%) patients. The mean age was 32.77±8.24 years in the SEI and 29.36±7.32 years in the ET. …”
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Simultaneous Quantification of Pioglitazone and Omarigliptin in Rat Plasma by UHPLC-MS/MS and Its Application to Pharmacokinetic Study after Coadministration of the Two Drugs by Lin Wang, Jiaxi Wang, Chao Lin, Furong Wang, Xiangping Li, Wanhui Liu

“…In this study, a rapid and reliable method for the simultaneous determination of the pioglitazone and omarigliptin in rat plasma by UHPLC-MS/MS was established and validated for the first time. An exsil mono C18 column (2.0 × 50 mm, 3 μm) was used to separate the analytes and the column temperature was kept at 30°C. …”
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Effects of Indwelling Pleural Catheter on Severe Acute Pancreatitis: A Retrospective Study by Qian Yao, Siyang Peng, Yanping Wu, Pi Liu

“…In addition, the survival analysis showed the risk of death in the PE group was higher than the non-PE group (HR 6.6, 95% CI, 3.67–11.86, and p<0.001). And the risk of death in group 1 was lower than group 2 (HR 0.26, 95% CI, 0.08–0.84, and p=0.025). …”
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Spatial analysis and associated risk factors of HIV prevalence in Botswana: insights from the 2021 Botswana AIDS Impact Survey (BAIS V) by Sethunya R. Simela, Matlhogonolo Kelepile, Thabo I. Sebobi

“…Spatial analysis showed Central Mahalapye as the district with the highest HIV prevalence rate (33.7%). Further, a high HIV prevalence cluster was found in the northeastern region of Botswana, while urban districts like Gaborone had significantly lower rates (11.2%). …”
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High-Risk Genotypes Associated with Poor Response to Controlled Ovarian Stimulation in Indian Women by Anuradha Udumudi, K. Chaitra Lava, Vandana Hegde

“…Results: Strong association of c.146G>T of AMH, c.622-6C>T of AMHR2, c.453-397T>C and c.975G>C of ESR1, c.2039G>A of FSHR and c.161+4491T>C of LHCGR with infertility and response to COS was established. …”
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Sleep patterns and smartphone use among left-behind children: a latent class analysis and its association with depressive symptoms by Xue Han, Cheng-Han Li, Heng Miao, Su Xu, Wen-Jing Yan, Juan Chen, Juan Chen

“…The Limited Sleep High Users class reported the highest levels of depressive symptoms (M = 11.60, SE = 0.0658), while the Sufficient Sleep Low Users class reported the lowest (M = 3.67, SE = 0.0346). A linear relationship between sleep duration and depressive symptoms was observed. …”
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Clinico-Epidemiological Profile of Children Orphaned due to AIDS Residing in Care Giving Institutions in Coastal South India by Rekha Thapar, Meher Singha, Nithin Kumar, Prasanna Mithra, Bhaskaran Unnikrishnan, Ramesh Holla, Vaman Kulkarni, B. B. Darshan, Avinash Kumar

“…Most of the children orphaned by AIDS (n=78, 90.7%) had a history of both the parents being HIV positive. …”
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Physical development and sociocultural context influences on children’s physical activity by Alessandro Hervaldo Nicolai Ré, Maria Teresa Cattuzzo, David Stodden, Guilherme dos Santos, Albert Lucas Olinto Tertuliano, Carlos Bandeira de Mello Monteiro, Diogo Henrique Constantino Coledam, Anthony David Okely

“…For girls, active leisure with balls (OR 28.91; 95%CI 6.88–121.50) and without balls (OR 4.32; 95%CI 1.95–9.57) enhanced the odds of compliance with PA guidelines, without effect of maternal education. …”
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Observational pilot using a Data to Care intervention strategy to promote HCV re-engagement and cure for persons with HIV/HCV co-infection who are out of care by Maximilian Wegener, Deborah Gosselin, Ralph Brooks, Suzanne Speers, Merceditas Villanueva

Subjects: “…Hepatitis C virus (HCV)…”
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dyphAI dynamic pharmacophore modeling with AI: a tool for efficient screening of new acetylcholinesterase inhibitors by Yasser Hayek-Orduz, Dorian Armando Acevedo-Castro, Dorian Armando Acevedo-Castro, Juan Sebastián Saldarriaga Escobar, Brandon Eli Ortiz-Domínguez, María Francisca Villegas-Torres, Paola A. Caicedo, Álvaro Barrera-Ocampo, Natalie Cortes, Edison H. Osorio, Andrés Fernando González Barrios

“…This ensemble captures key protein-ligand interactions, including π-cation interactions with Trp-86 and several π-π interactions with residues Tyr-341, Tyr-337, Tyr-124, and Tyr-72. The protocol identified 18 novel molecules from the ZINC database with binding energy values ranging from −62 to −115 kJ/mol, suggesting their strong potential as AChE inhibitors. …”
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Impact of pediatric COVID-19 isolation on children’s well-being and caregiver mental health by Song I. Yang, Chi-Hyun Choi, Eun Joo Lee, Sun Hee Jee, Mi Seon Han

“…Approximately 36.7% of caregivers showed at least moderate levels of depression during isolation, which significantly decreased to 14.3% three months after discharge (P = 0.032). …”
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Suicidal ideation and its associated risk factors among students of a medical college in Chennai—A cross-sectional study by M Koushik, Prarthana Veeramani, L Pooja Mary Vaishali, B Charumathi, Timsi Jain

“…Factors like the presence of depression, anxiety, stress, dissatisfied lifestyle, history of smoking, drugs, and alcohol consumption were found to be contributing to suicidal ideation. About 37.7% of the study population felt that they knew about the danger signs of suicide. …”
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Prognostic impact of donor mitochondrial genomic variants in myelodysplastic neoplasms after stem-cell transplantation by Jing Dong, Shahram Arsang-Jang, Tao Zhang, Zhongyuan Chen, Yung-Tsi Bolon, Stephen Spellman, Raul Urrutia, Paul Auer, Wael Saber

“…In the entire donor cohort, we identified 1,825 mtDNA variants, including 67 potential pathogenic variants. Genetic variants on MT-CYB and MT-ND5 genes were identified as independent predictors of posttransplant outcomes. …”
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The Clinical Effects of Intravascular Ultrasound-Guided Percutaneous Coronary Intervention in Patients with Chronic Total Occlusion: A Meta-Analysis by Zhaoshuang Zhong, Long Zhao, Kaiming Chen, Shuyue Xia

“…Compared to the angiography-guided group, IVUS-guided PCI showed no significant reduction in the incidence of MACE (I2 = 27.4%, P = 0.239; RR 0.929, 95% CI 0.765 to 1.128, P = 0.457), cardiac death (I2 = 0.0%, P = 0.459; RR 0.574, 95% CI 0.299 to 1.103, P = 0.096), all-cause death (I2 = 0.0%, P = 0.964; RR 0.677, 95% CI 0.395 to 1.163, P = 0.158), MI (I2 = 46.7%, P = 0.131; RR0.836, 95% CI 0.508 to 1.377, P = 0.482), and TVR (I2 = 21.2%, P = 0.279; RR 0.929, 95% CI 0.679 to 1.272, P = 0.648). …”
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C-Reactive Protein As A Response Indicator In Drug-Naïve Patients With Major Depressive Disorder: A Hospital-Based Study by Ather Muneer, Nargis Munir, Nadia Shams, Mirza Inam, Usman Ghani, Neelam Ayub

Subjects: “…C-Reactive Protein…”
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Effect of Sexual Skills Counseling With Cognitive-Behavioral Approach on Sexual Assertiveness in Women Suffering from Marital Disillusionment by Faezeh Saffari Mofrad, sakineh Taherkhani, Ashraf Khoramirad

“…These values for the control group were 33.5±11.00, 36.7±10.64, and 37.3±11.08, respectively. According to the results, the mean score of sexual assertiveness between the intervention and control groups and at the examined three time points had a statistically significant difference (P<0.001). …”
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Prednisolone versus antihistamine for allergic rhinitis: No significant difference found in randomized trial by Carl Skröder, Laila Hellkvist, Ulla Westin, Pernilla Sahlstrand‐Johnsson, Kerstin Hansson, Agneta Karlsson, Åslög Dahl, Leif Bjermer, Lars Olaf Cardell

“…This was marginally lower than the control group, with an AUC of 32.6 (SD = 13.2, 95% CI = 25.6–39.7). The difference was not statistically significant (p = 0.80). …”
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Assessing the stability of psychobiological stress reactivity during adolescence: mixed-effect modelling of cortisol responses to laboratory stressors [version 2; peer review: 2 ap... by Elizabeth Susman, Jen O'Shea, Samantha Dockray

“…Results Results of a linear mixed-effect model found there to be a significant difference in cortisol reactivity over time, indicating that cortisol stress reactivity did not remain stable during this time (Estimate= 3.39, t=3.67, p<.001, CI[1.56, 5.22]). Additionally, results show children and adolescents who developed slower/quicker than peers displayed decreased stress reactivity (Estimate= -3.59, t=-2.13. p=.03, CI[-6.92, -0.25]). …”
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