Editorial by Jörg Tremmel, Maria Lenk, Antony Mason, Markus Rutsche

“…Jamie McQuilkin, who is the winner of the 2016/17 Demography Prize, derives an additional index from national statistics in the opening article of this second part of the IGJR double issue on “Measuring Intergenerational Justice for Public Policy”. …”
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Defining indicators for disease burden, health outcomes, policies and barriers and facilitators to health services for migrant populations in the Middle East and North African regi... by Charles Agyemang, Ali Ardalan, Farah Seedat, Bouchra Assarag, Nuria Casamitjana, Kolitha Wickramage, Sally Hargreaves, Ana Requena-Mendez, Fouad M Fouad, Dominik Zenner, Anna Deal, Stella Evangelidou, Wafa Saidi, Chiaki Ito, Oumnia Bouaddi, Moudrick Abdellatifi, Alba Cuxart-Graell, Hassan Edries, Eman Elafef, Taha Maatoug, Anissa Ouahchi, Liv Mathilde Pampiri, Sara Arias, Adel Abdelkhalek, Ahmed Hamed Arisha, Ibrahim Ahmed Bani, Aasmaa Chaoui, Wafa Chemao-Elfihri, Kenza Hassouni, Mahmoud Hilali, Mohamed Khalis, Wejdene Mansour, Ali Mtiraoui, MENA Migrant Health Working Group, Asad Adam, Adnene Ben Haj Aissa, Salma Altyib, Hanen Ben Belgacem, Imane Belkhammar, Thomas Calvot, Luciana Ceretti, Nelly Chavassieux, Hassan Chrifi, Mohamed Douagi, Algdail Elnil, Gonzalo Fanjul, Ahmed Hamed, Abdedayem Khelifi, Lora Makhlouf, Maissa Mokni, Davide Olchini, Tarik Oufkir, Nasong Park, Giuseppe Raffa, Sandra Santafé, Alice Sironi, Fatma Temimi, Zeineb Turki

“…This protocol describes a suite of seven systematic reviews that aim to identify, appraise and synthesise the available evidence on the burden and health outcomes, policies and access (barriers and facilitators) related to these mobile populations in the region.Methods Seven systematic reviews will cover three questions to explore the: (1) burden and health outcomes, (2) policies and (3) healthcare barriers and facilitators for the following seven disease areas in migrants in the MENA region: tuberculosis, HIV and hepatitis B and C, malaria and neglected tropical diseases, diabetes, mental health, maternal and neonatal health, and vaccine-preventable diseases. …”
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A prospective observational cohort study of HIV infection in Indonesia: baseline characteristics and one-year mortality by Tuti P. Merati, Evy Yunihastuti, Rudi Wisaksana, Nia Kurniati, Dona Arlinda, Muhammad Karyana, Nugroho H. Susanto, Dewi Lokida, Herman Kosasih, Aly Diana, Lois E. Bang, Melinda Setiyaningrum, Desrinawati M. Amin, Eppy Eppy, Wiwit A. S. N. Cahyawati, Emon W. Danudirgo, I Made Gede Darmaja, Nur Farhanah, Carta A. Gunawan, Usman Hadi, Kurnia F. Jamil, Sudirman Katu, Tambar Kembaren, I Gede Rai Kosa, Danang L. Norosingomurti, Asep Purnama, Ida S. Laksanawati, Adria Rusli, I Ketut Agus Somia, Yanri W. Subronto, Ivan L. Toruan, Renee Ridzon, C. Jason Liang, Aaron T. Neal, Ray Y. Chen, INA-PROACTIVE Study Group

“…Detectable viremia at enrollment was significantly associated with mortality, with the risk increasing as the viral load (VL) category increased (adjusted hazard ratio [aHR] 4.47, 95% CI: 1.47–13.56 for VL 50 to < 1,000 copies/mL; aHR 7.88, 95% CI: 2.80–22.20 for VL 1,000 to 10,000 copies/mL; and aHR 18.33, 95% CI: 7.94–42.34 for VL > 10,000 copies/mL; compared to VL < 50 copies/mL). …”
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Differential Prognosis of True Bifurcation Lesions According to Left Main Versus Non–Left Main Location and Treatment Strategy by Ki Hong Choi, Chang‐Wook Nam, Francesco Bruno, Yun‐Kyeong Cho, Leonardo De Luca, Jeehoon Kang, Alessio Mattesini, Young Bin Song, Alessandra Truffa, Hyo‐Soo Kim, Wojciech Wańha, Woo Jung Chun, Sebastiano Gili, Gerard Helft, Seung Hwan Han, Bernardo Cortese, Cheol Hyun Lee, Javier Escaned, Hyuck‐Jun Yoon, Alaide Chieffo, Joo‐Yong Hahn, Guglielmo Gallone, Seung‐Hyuk Choi, Gaetano De Ferrari, Bon‐Kwon Koo, Giorgio Quadri, Seung‐Ho Hur, Fabrizio D'Ascenzo, Hyeon‐Cheol Gwon, Ovidio de Filippo

“…Results In patients with an LM bifurcation, those with a true bifurcation had a significantly higher risk of a MACE than those with a nontrue bifurcation (20.2% versus 13.4%, adjusted hazard ratio [HR], 1.44 [95% CI, 1.11–1.86]; P=0.006). Conversely, there was no significant difference in the risk of a MACE according to true versus nontrue bifurcation in patients with non‐LM bifurcation lesions (9.0% versus 8.8%; adjusted HR, 1.02 [95% CI, 0.82–1.27]; P=0.849). …”
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ارزیابی میزان تحمل ژنوتیپ‌های متنوع گندم به تنش گرمایی آخر فصل by مریم ترابی, سعید نواب پور, سعید یاراحمدی

“…بر اساس عملکرد در شرایط بدون تنش (YP) و تنش (YS) شاخص‌های تحمل تنش از قبیل شاخص تحمل تنش (STI)، شاخص تحمل (TOL)، میانگین هندسی عملکرد (GMP)، شاخص میانگین تولید (MP)، شاخص میانگین هارمونیک (HM)، شاخص عملکرد (YI)، شاخص تنش نسبی (RDI) و شاخص پایداری عملکرد (YSI) محاسبه شدند.یافته‌ها: نتایج نشان داد که شاخص‌های STI، GMP، HM وMP همبستگی مثبت و بالایی با عملکرد در شرایط بدون تنش و تنش داشتند و ژنوتیپ‌های با مقادیر عددی بزرگ برای این شاخص‌ها، عملکرد بالایی در شرایط تنش و عدم تنش داشتند (گروه A فرناندز) که شامل ژنوتیپ‌های 51، 12، 24، 85، 6، 120، 47، 94 (بهار)، 72، 114، 91، 131، 16 و 127 بودند. …”
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Racial Differences in Systemic Immune Parameters in Individuals With Lung Cancer by Mitchell S. von Itzstein, MD, Jialiang Liu, PhD, Hong Mu-Mosley, PhD, Farjana Fattah, PhD, Jason Y. Park, MD, PhD, Jeffrey A. SoRelle, MD, J. David Farrar, PhD, Mary E. Gwin, MD, David Hsiehchen, MD, Yvonne Gloria-McCutchen, Edward K. Wakeland, PhD, Suzanne Cole, MD, Sheena Bhalla, MD, Radhika Kainthla, MD, Igor Puzanov, MD, MSCI, Benjamin Switzer, DO, MHSA, MS, Gregory A. Daniels, MD, PhD, Yousef Zakharia, MD, Montaser Shaheen, MD, Jianjun Zhang, MD, PhD, Yang Xie, PhD, David E. Gerber, MD

“…Compared with White patients, Black patients had greater comorbidity (median Charlson Comorbidity Index 5 versus 3; p = 0.04) and were more likely to have received previous chemotherapy (79% versus 47%; p = 0.03). Black patients had significantly lower levels of CCL23 and CCL27 and significantly higher levels of CCL8, CXCL1, CCL26, CCL25, CCL1, IL-1b, CXCL16, and IFN-γ (all p < 0.05, false discovery rate < 0.1). …”
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LungDiag: Empowering artificial intelligence for respiratory diseases diagnosis based on electronic health records, a multicenter study by Hengrui Liang, Tao Yang, Zihao Liu, Wenhua Jian, Yilong Chen, Bingliang Li, Zeping Yan, Weiqiang Xu, Luming Chen, Yifan Qi, Zhiwei Wang, Yajing Liao, Peixuan Lin, Jiameng Li, Wei Wang, Li Li, Meijia Wang, YunHui Zhang, Lizong Deng, Taijiao Jiang, Jianxing He

“…This study employed a large cohort of 31,267 EHRs from multiple centers for model training and internal testing. …”
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Application of Concentration-Area fractal modeling and artificial neural network to identify Cu, Zn±Pb geochemical anomalies in Hashtjin area, NW of Iran by Ali Imamalipour, Hamed Ebrahimi, Amir reza Abdollahpur

“…Recent research investigations have shown that Machine Learning (ML) algorithms can identify geochemical anomalies associated with mineralization that represent targets for mineral exploration. …”
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واسنجی مدل SWAT با تلفیق الگوریتم تکاملی PSO و روش تاگوچی by حسین شیرانی, انیس اسدی, سمیه صدر, علی اصغر بسالت پور, عیسی اسفندیار پور

“…به‌طوری‌‌که در مرحله واسنجی شاخص‌های r-factor و p-factor به‌ترتیب 1.23 و 0.88 و ضرایب تبیین و نش-‌ساتکلیف نیز به‌ترتیب برابر 0.77 و 0.75 بودند. در مرحله اعتبارسنجی نیز شاخص‌های r-factor و p-factor به‌ترتیب 1.31 و 0.84 و ضرایب تبیین و نش-‌ساتکلیف نیز به‌ترتیب برابر 0.72 و 0.73 بودند. …”
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Comparative analysis of C-Reactive protein levels among Non-comorbid, Comorbid, and Multimorbid Hospitalized COVID-19 patients by Maria Shoukat, Haseeb Khan, Moona Nazish, Abdur Rehman, Sheharyar Raashid, Saad Ahmed, Wajid Munir, Abdulwahed Fahad Alrefaei, Massab Umair, Muhammad Osama Bin Abid, Nasim Akhtar, Wajid Zaman, Malik Badshah

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ارزیابی مدلهای تلفیقی هوش مصنوعی در تخمین غلظت مواد جامد محلول در بالادست شهر ساری by علیرضا قائمی, مهدی اژدری مقدم, سارینا کیخا

“…حجم ورود پساب‌های شهری و کشاورزی به این رودخانه، باعث افزایش مقادیر آلاینده‌ها شده، به‌طوری‌که در بازه سال‌های 1372 تا انتهای سال 1396، میانگین آلاینده‌های موجود در ایستگاه ورند برای سه آلاینده مواد جامد محلول، کلر و سدیم به‌ترتیب برابر 507.49، 2.16 و 2.47 بوده است. بنابراین، برآورد دقیق پارامترهای کیفیت آب، یک نیاز اساسی برای مدیریت کیفیت آب، سلامت انسان، مصرف عمومی و مصارف خانگی است. …”
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Ukrayna by Valery Morkva

“…Üsküdar Üniversitesi’nden Sait Ocaklı, 17. yüzyılda Kırım Hanlığı’nın kuzey politikasını, Hacettepe Üniversitesi’nden Ufuk Aykol ise Zaporijya Siçi’nin yıkılmasını ve Kırım Hanlığı üzerindeki etkisini ele almıştır. …”
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Determining the Heterotic Groups of Selected Grain Maize (Zea mays L.) Inbred Lines using Morphological and Phenological Traits by Mahnaz Oroojloo, Sara Dezhsetan, Behzad Ahmadi, Mohammadreza Shiri, Ali Moghaddam

“…The highest percentage genotypic coefficient of variation was obtained for kernel yield (31.77%), ear height (20.07%), percentage of cob wood (19.96%), the number of kernels per row (17.35%), and 1000-kernel weight (16.8%) traits. …”
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Effects of non-pharmacological interventions on depressive and anxiety symptoms in pregnant women: a systematic review and network meta-analysisResearch in context by Guowei Zeng, Jianfeng Niu, Ke Zhu, Fei Li, Liwen Li, Kaiming Gao, Yanlong Zhuang, Boyang Zhang, Xiaoqiang Han, Gang Ye, Zhikun Gao, Haobai Li

“…In the subgroup analysis of healthy populations, muscle acupoint therapy (SUCRA = 77.17%; SMD = −0.89, 95% CrI = −1.55, −0.23; N = 99) and mind-body exercise (SUCRA = 47.54%; SMD = −0.53, 95% CrI = −0.88, −0.19; N = 352) also significantly reduce depressive symptoms. …”
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O delírio segundo Freud e Jung: aportes recíprocos e distinções by Carlos Augusto Pereira Viana

“…O tratamento dessa problemática, além de contribuir na direção já apontada de tomá-la com o devido rigor e justiça científica, fornece com certeza importantes aportes para futuros estudos sobre a problemática em questão. …”
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Triglyceride-glucose-body mass index and the incidence of cardiovascular diseases: a meta-analysis of cohort studies by Xiyun Rao, Ziyi Xin, Qingwen Yu, Lanlan Feng, Yongmin Shi, Ting Tang, Xuhan Tong, Siqi Hu, Yao You, Shenghui Zhang, Jiake Tang, Xingwei Zhang, Mingwei Wang, Ling Liu

“…The results indicated that Compared with the lowest TyG-BMI index category, the highest TyG-BMI index was related to a higher incidence of cardiovascular diseases (CVD) (HR = 1.62; 95% confidence interval (CI): 1.35–1.95; I2 = 94%),coronary artery disease (CAD) (HR = 1.69; 95% (CI): 1.23–2.31; I2 = 94%). stroke(HR = 1.57; 95% (CI): 1.11–2.23; I2 = 94%).In the dose–response analysis, there was a linear association of the TyG-BMI index with the risk of CVD (Pnonlinear = 0.223), CAD (Pnonlinear = 0.693), and stroke (Pnonlinear = 0.122)No significant effects were observed regarding participants’ gender, length of follow-up, sample size or mean age(P > 0.05). …”
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Serum NFL and neuropsychological performance over ∼8 years in women with and without HIV: a longitudinal repeated measures studyResearch in context by Deborah R. Gustafson, Xuantao Li, Alison E. Baird, Henrik Zetterberg, Kaj Blennow, Jinbing Zhang, Amanda Blair Spence, Pauline Maki, Anjali Sharma, Kathleen Weber, Recai Yucel

“…Multivariable linear regression analyses stratified by HIV serostatus examined cross-sectional baseline and follow-up associations, and ∼8-year change in sNFL level related to global and domain-specific NP T-scores. Findings: 417 participants (290 WLWH, 127 WLWOH), African American/Black (55%), ≥high school education (69%), current/former smokers (79%), and overweight/obese (BMI ≥25.0 kg/m2, 74%) were included. …”
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Immunosuppressive treatment results in patients with primary IgA nephropathy in Turkiye; the data from TSN-GOLD working group by Aysegul Oruc, Abdullah Sumnu, Aydın Turkmen, Taner Basturk, Egemen Cebeci, Kenan Turgutalp, Hakkı Cetinkaya, Müge Uzerk Kibar, Nurhan Seyahi, Erhan Tatar, Metin Ergul, Ülver Derici, Mehmet Deniz Aylı, Musa Pınar, Betül Bakar, Rümeyza Kazancıoglu, Abdülmecit Yıldız, Ahmet Burak Dirim, Zülfükar Yılmaz, Kültigin Turkmen, Onur Tunca, Mehmet Koc, Sim Kutlay, Hasan Micozkadıoglu, Alper Azak, Burcu Boztepe, Sedat Ustundag, Seda Şafak Ozturk, Abdulkadir Unsal, Serhat Karadag, Gülizar Sahin, Ezgi Coşgun Yenigun, Necmi Eren, Mustafa Gullulu, Meltem Gursu, Savaş Ozturk

“…A total of 408 primary IgAN patients treated with IST (65.4% male, mean age 38.4 ± 12.5 years, follow-up 30 (3–218) months) were included and divided into two groups according to treatment protocols (isolated corticosteroid [CS] 70.6% and combined IST 29.4%). Treatment responses, associated factors were analyzed.Results Remission (66.7% partial, 33.7% complete) was achieved in 74.7% of patients. …”
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First Detection of <i>Alphacoronavirus</i> in Bats from the World’s Largest Wetland, the Pantanal, Brazil by Tayane B. S. Magalhães, Amanda de O. Viana, Thiago B. F. Semedo, Juliane S. Saldanha, Nicole A. dos Reis, Nathalia de A. Pereira, Rachel V. P. de Barros, Hannah R. Miranda, Gabriella C. Almeida, Desyrée Y. S. R. Ozaki, Giovana S. Caleiro, Gustavo O. Fenner, Fernanda P. Vizu, Theo Kraiser, Thais P. Carvalho, Luciano M. Thomazelli, Erick G. Dorlass, Clarice W. Arns, Helena L. Ferreira, Erika Hingst-Zaher, Rogério Vieira Rossi, Guilherme S. T. Garbino, Edison L. Durigon, Jansen de Araujo, Daniel M. de Aguiar

“…Orthocoronavirinae was detected in 16.7% (70/419) of the bats; nine samples were sequenced, confirming that <i>Carollia perspicillata</i> (4), <i>Phyllostomus hastatus</i> (2), <i>Desmodus rotundus</i> (1), <i>Molossus rufus</i> (1), and <i>Myotis</i> cf. …”
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Convergent construct validity and test-retest reliability of both German versions of the original and the revised Niigata PPPD Questionnaire: NPQ and NPQ-R by Sarah Chételat, Sarah Chételat, Eve-Yaël Gerber, Eve-Yaël Gerber, Sarah El Khadlaoui, Frank Behrendt, Frank Behrendt, Michaela Stark, Michaela Stark, Stefan Schädler, Stefan Schädler, Maximilian Maywald, Lena Fabritius, Johannes Gerb, Johannes Gerb, Denis Grabova, Wiebke Trost, Andreas Zwergal, Andreas Zwergal, Ralf Strobl, Ralf Strobl, Katrin Parmar, Katrin Parmar, Hans Ulrich Gerth, Hans Ulrich Gerth, Leo H. Bonati, Leo H. Bonati, Leo H. Bonati, Sandra Becker-Bense, Corina Schuster-Amft, Corina Schuster-Amft, Corina Schuster-Amft

“…Internal consistency, test-retest reliability, SEM and MDC calculated for NPQ/NPQ-R were α = 0.88/α = 0.91, ICC=0.83 (CI 0.77 to 0.0.87), SEM 5.55/8.37, and MDC 15/23 points.ConclusionThe German versions of NPQ and NPQ-R are valid and reliable patient-reported outcome measures for assessing PPPD, demonstrating satisfactory psychometric measurement properties including convergent construct validity and reliability parameters: internal consistency, test-retest reliability, SEM, and MDC as an evaluative measure. …”
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