Renin–angiotensin–aldosterone system activation in plasma as marker for prognosis in critically ill patients with COVID-19: a prospective exploratory study by Katharina Krenn, Felix Kraft, Luana Mandroiu, Verena Tretter, Roman Reindl-Schwaighofer, Theresa Clement, Oliver Domenig, Matthias G. Vossen, Gregor Riemann, Marko Poglitsch, Roman Ullrich

“…Ang II and active ACE2 were inversely associated with survival (OR 0.07; 95%CI 0.01, 0.39 and OR 0.10; 95%CI 0.01, 0.63) while higher Ang 1–7 predicted favorable outcome (OR 6.8; 95%CI 1.5, 39.9). …”
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Comparison of Field and Virtual Vegetation Surveys Conducted Using Uncrewed Aircraft System (UAS) Imagery at Two Coastal Marsh Restoration Projects by Aaron N. Schad, Molly K. Reif, Joseph H. Harwood, Christopher L. Macon, Lynde L. Dodd, Katie L. Vasquez, Kevin D. Philley, Glenn E. Dobson, Katie M. Steinmetz

“…., species composition and abundance). However, surveys can be costly, time-consuming, and only provide data at discrete locations, leaving potential data gaps across a site. …”
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Performance of the AmpliSeq NGS panel in thyroid nodules with indeterminate cytology by Wiame Potonnier, Erell Guillerm, Claude Bigorgne, Cécile Ghander, Malanie Roy, Florence Coulet, François Ansart, Fabrice Menegaux, Laurence Leenhardt, Isabelle Brocheriou, Gabrielle Deniziaut, Camille Buffet

“…Panel performances assessed in the grouped categories Bethesda III and IV demonstrated a 55.0% (95% CI: 31.5; 76.9) sensitivity, a 76.9% (95% CI: 66.0; 85.7) specificity, a 37.9% (95% CI: 25.7; 51.9) PPV and an 87.0% (95% CI: 80.2; 91.7) NPV, considering a 20% prevalence of malignancy. …”
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Automated multidimensional deep learning platform for referable diabetic retinopathy detection: a multicentre, retrospective study by Chi Pui Pang, Weiqi Chen, Mingzhi Zhang, Tsz Kin Ng, Yi Zheng, Guihua Zhang, Jian-Wei Lin, Ji Wang, Jie Ji, Ling-Ping Cen, Peiwen Xie, Yongqun Xiong, Hanfu Wu, Dongjie Li

“…With reference to the ground truth, the DL system showed comparable performance (Cohen’s κ: 0.86–0.93; Gwet’s AC1: 0.89–0.94) with three DR experts (Cohen’s κ: 0.89–0.96; Gwet’s AC1: 0.91–0.97) in detecting referable lesions.Conclusions The automatic DL system for detection of referable DR based on the UK guideline could achieve high accuracy in multidimensional classifications. …”
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Association between retinal morphological characteristics and visual function in myopic traction maculopathy by Mengai Wu, Lifeng Chen, Yuanyuan Fan, Li Lin, Haidong Li, Zhijie Wang, Guanshun Yu, Xinyue Wu, Bin Zheng, Fan Lu

“…Methods: This cross-sectional study included 19 eyes with myopic foveoschisis (MF) and foveal detachment (FD), 37 eyes with MF without FD, and 24 myopic eyes as control. …”
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The Effect of Mulching on the Root Growth of Greenhouse Tomatoes Under Different Drip Irrigation Volumes and Its Distribution Model by Jiankun Ge, Yuhao Zhu, Xuewen Gong, Chuqi Yao, Xinyu Wu, Jiale Zhang, Yanbin Li

“…In the N0.9 treatment, root length density had a bivariate cubic polynomial relationship with soil water and temperature, with a coefficient of determination (<i>R</i>²) of 0.97 and a normalized root mean square error (NRMSE) of 20%. (4) When introducing the film mulching factor (<i>f_m</i>) and water stress factor (<i>K_s</i>) into the root distribution model to simulate the root length density distribution of Y0.9 and Y0.5, it was found that the NRMSE was 22% and <i>R</i>² was 0.90 under the Y0.9 treatment, and the NRMSE was 24% and R² was 0.98 under the Y0.5 treatment. …”
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Effect of practicing water-saving irrigation on greenhouse gas emissions and crop productivity: A global meta-analysis by Mingdong Tan, Ningbo Cui, Shouzheng Jiang, Liwen Xing, Shenglin Wen, Quanshan Liu, Weikang Li, Siwei Yan, Yaosheng Wang, Haochen Jin, Zhihui Wang

“…MAP, pH, organic carbon (OC) and bulk density (BD) were identified as key factors responsible for the emissions of CO2 (16.37 %), CH4 (17.35 %) and N2O (20.19 %) as well as crop yield (16.21 %), respectively. …”
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Life course socioeconomic position and care dependency in later life: a longitudinal multicohort study from 17 countriesResearch in context by Ting Pan, Chenshuang Li, Ying Zhou

“…Individuals who experienced a severe SES decline—high in childhood but low in adulthood—showed a more than ten times higher risk (IADL: OR 18.26, 95% CI 12.45–26.79; ADL: 11.95, 8.47–16.88). A lower risk was observed for those who moved from low SES in childhood to high SES in adulthood (IADL: 2.51, 1.00–6.33; ADL: 1.52, 0.62–3.72). …”
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Sport-related concussion in Brazilian professional soccer: A four-year prospective epidemiological analysis by Guilherme Corrêa de Araújo Moury Fernandes, Ewerton Borges de Souza Lima, Paulo Henrique Schmidt Lara, Ana Camila de Castro Gandolfi, Jorge Roberto Pagura, Gustavo Gonçalves Arliani, Moisés Cohen

“…A total of 299 CMFT cases were reported, with a median incidence of 2.37 per 1 000 ​h of play. Among them, there were 178 head and 121 face traumas, which led to 87 SRC (representing 29.10% of all CMFT), with an incidence of 0.69. …”
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Rede Brasileira de Pesquisas em Tuberculose (REDE-TB): missão de desenvolvimento científico para eliminar a tuberculose by Rander Junior Rosa, Ana Beatriz Marques Valença, Letícia Perticarrara Ferezin, Natacha Martins Ribeiro, Paula Daniella de Abreu, Rubia Laine de Paula Andrade, Willie Otávio Bueno Bernardi, Diogo Henrique Mendes da Silva, Aline Aparecida Monroe, Erica Chimara Silva, Vânia Maria Silva Araújo, Anna Cristina Calçada Carvalho, Ethel Leonor Noia Maciel, Ana Paula Junqueira-Kipnis, Jose Roberto Lapa e Silva, Lia Gonçalves Possuelo, Ricardo Alexandre Arcêncio

“…Resultados:Identificou-se 670 publicações, com 447 incluídas na revisão. Dentre estas, 315 (70,5%) foram publicadas em periódicos internacionais. …”
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Oncolytic influenza virus enhances killing effect of gemcitabine against pancreatic cancer cells by MENG Zihe, MENG Zihe, XU Yongru, DENG Zhaoda

“…The virus was then comprehensively characterized through chicken red blood cell hemagglutination assay， transmission electron microscopy， and viral replication assay. CCK-8 assay was utilized to determine the impact of OvFlu-GM-CSF viruses ［multiplicities of infection （MOI）： 0， 0.1， 1.0， 3.0］ on the survival rate of pancreatic cancer cell lines （Panc02， PANC-1， SW1990， BxPC-3） and normal pancreatic ductal epithelial cells （HPDE6-C7） after treatment for 24， 48 or 72 h. …”
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The Antiobesity Effect of GLP-1 Receptor Agonists Alone or in Combination with Metformin in Overweight /Obese Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Ana... by Xiaorui Lyu, Taibiao Lyu, Xue Wang, Huijuan Zhu, Hui Pan, Linjie Wang, Hongbo Yang, Fengying Gong

“…A total of eight eligible RCTs were finally enrolled in our meta-analysis from the 587 retrieved literature. The results showed that GLP-1RAs alone or combined with MET was associated with a greater weight loss (N = 318, WMD = −2.61, 95% CI: −3.51 to −1.72, P≤0.001, I2 = 77.5%), more obvious reduction of waist circumference (N = 276, WMD = −3.46, 95% CI: −4.36 to −2.56, P≤0.001, I2 = 0.0%), and body mass index (BMI) (N = 318, WMD = −0.93, 95% CI: −1.60 to −0.26, P=0.007, I2 = 84.9%) in overweight/obese PCOS patients when compared with MET alone. …”
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UGCG promotes chemoresistance and breast cancer progression via NF-κB and Wnt/β-catenin pathway activation by Li Long, Lei Wang, Yiran Liang, Fangzhou Ye, Yuhan Jin, Dan Luo, Xiaoyan Li, Yajie Wang, Yaming Li, Dianwen Han, Bing Chen, Wenjing Zhao, Lijuan Wang, Qifeng Yang

“…Additionally, findings from our cohorts indicated that higher levels of UGCG expression correlated with a lower rate of pathological complete response (pCR), suggesting it could serve as an independent predictor of chemotherapy effectiveness. …”
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Mechanical chest compression increases intrathoracic hemorrhage complications in patients receiving extracorporeal cardiopulmonary resuscitation by Yoshihisa Matsushima, Tatsuhiro Shibata, Kodai Shibao, Rei Yamakawa, Miyu Hayashida, Toshiyuki Yanai, Takashi Ishimatsu, Takehiro Homma, Shoichiro Nohara, Maki Otsuka, Yoshihiro Fukumoto

“…The 180-day survival rates did not differ significantly between groups (27.7% vs. 25.0%, log-rank p = 0.540). Conclusions: Mechanical CPR during ECPR is associated with an increased risk of severe intrathoracic hemorrhage. …”
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Myocardial Infarction-Associated Shock: A Comprehensive Analysis of Phenotypes, SCAI Classification, and Outcome Assessment by Stanislav Dil, Maria Kercheva, Oleg Panteleev, Sergey Demianov, Aleksandr Kanev, Nina Belich, Boris Kornienko, Vyacheslav Ryabov

“…The overall mortality rate was significantly higher in the MS group (68% vs. 53%, RR = 1.438, 95% CI: 1.041–1.986, <i>p</i> = 0.03). Logistic regression identified mechanical ventilation (OR = 8.33, 95% CI: 2.54–22.80, <i>p</i> = 0.012), elevated lactate levels (OR = 1.20, 95% CI: 1.02–1.41, <i>p</i> = 0.026), and cardiopulmonary resuscitation (CPR) (OR = 7.97, 95% CI: 2.51–24.40, <i>p</i> < 0.0001) as independent predictors of mortality. …”
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The Effect of Adjuvant Radiotherapy on One- and Two-Stage Prosthetic Breast Reconstruction and on Autologous Reconstruction: A Multicenter Italian Study among 18 Senonetwork Breast... by Andrea Vittorio Emanuele Lisa, Marzia Salgarello, Alessandra Huscher, Fabio Corsi, Daniele Piovani, Federica Rubbino, Stefania Andreoletti, Giovanni Papa, Francesco Klinger, Corrado Tinterri, Alberto Testori, Marta Scorsetti, Paolo Veronesi, Maria Cristina Leonardi, Mario Rietjens, Umberto Cortinovis, Valeria Summo, Emanuele Rampino Cordaro, Pier Camillo Parodi, Paolo Persichetti, Mauro Barone, Giorgio De Santis, Matteo Murolo, Michele Riccio, Angelica Aquinati, Francesco Cavaliere, Nicola Vaia, Giulia Pagura, Erica Dalla Venezia, Franco Bassetto, Vincenzo Vindigni, Luigi Ciuffreda, Maria Alessandra Bocchiotti, Alberto Sciarillo, Nadia Renzi, Graziano Meneghini, Tajna Kraljic, Andrea Loreti, Lucio Fortunato, Valentina Pino, Valeriano Vinci, Marco Klinger

“…The risk for any complication was significantly increased in patients receiving PMRT (aOR, 1.73; 95% CI, 1.33–2.24; p<0.001). PMRT was associated with a significant increase in the risk of capsular contracture in the DTI and TE/I groups (aOR, 2.24; 95% CI, 1.57–3.20; p<0.001). …”
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Serum metabolome indicators of early childhood development in the Brazilian National Survey on Child Nutrition (ENANI-2019) by Marina Padilha, Victor Nahuel Keller, Paula Normando, Raquel M Schincaglia, Nathalia C Freitas-Costa, Samary SR Freire, Felipe M Delpino, Inês RR de Castro, Elisa MA Lacerda, Dayana R Farias, Zachary Kroezen, Meera Shanmuganathan, Philip Britz-Mckibbin, Gilberto Kac

“…Results: Twenty-eight top-ranked metabolites were included in linear regression models adjusted for the child’s nutritional status, diet quality, and infant age. Cresol sulfate (β=–0.07; adjusted-p &lt;0.001), hippuric acid (β=–0.06; adjusted-p &lt;0.001), phenylacetylglutamine (β=–0.06; adjusted-p &lt;0.001), and trimethylamine-N-oxide (β=–0.05; adjusted-p=0.002) showed inverse associations with DQ. …”
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Key Performance Indicators in Freestyle Swimming: Comparing Start, Turn, and Swimming Velocity in Top-Elite Female Junior and Adult Swimmers by Chantal Widmer, Julia Hernandez, Michael Romann, Wolfgang Taube, Dennis-Peter Born

“…Frontiers in Sports and Active Living, 4, Article 894066. https://doi.org/10.3389/fspor.2022.894066 Polach, M., Thiel, D., Kreník, J., & Born, D.-P. (2021). Swimming turn performance: The distinguishing factor in 1500 m world championship freestyle races? …”
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Hubungan Kadar LDL dan HDL Serum Ibu Hamil Aterm dengan Berat Lahir Bayi by Oktalia Sabrida, Hariadi ., Eny Yantri

“…Rerata kadar LDL serum ibu hamil aterm 138,52±37,86 mg/dl dengan 7 sampel (22,60%) kadar LDL &lt;101 mg/dl. …”
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How Antiretroviral Drug Concentrations Could Be Affected by Oxidative Stress, Physical Capacities and Genetics: A Focus on Dolutegravir Treated Male PLWH by Jessica Cusato, Anna Mulasso, Micol Ferrara, Alessandra Manca, Guido Accardo, Alice Palermiti, Miriam Antonucci, Gianluca Bianco, Francesco Chiara, Jacopo Mula, Maria Cristina Tettoni, Simone Cuomo, Giulia Trevisan, Stefano Bonora, Giovanni Di Perri, Corrado Lupo, Alberto Rainoldi, Antonio D’Avolio

“…In addition, pharmacogenetics can influence transporter activity, and thus drug exposure. …”
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