Automatic GPR detection of grouting defects behind the tunnel shield segments based on wavelet coherence analysis combined with modified Res-RCNN by Dengyi Wang, Ming Peng, Liu Liu, Xiongyao Xie, Zhenming Shi, Yaoying Liang, Jian Shen, Qiyu Wu

“…The wavelet coherence analysis enables the observation of grouting defects behind tunnel shield segments with interferences of steel rebars. It can be applied even when the defect reflection is very weak, such as when the SNR is less than −40 dBs. …”
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Emerging carbapenem-resistant Klebsiella pneumoniae in a tertiary care hospital in Lima, Peru by Fiorella Krapp, Diego Cuicapuza, Guillermo Salvatierra, Jean P. Buteau, Catherine Amaro, Lizeth Astocondor, Noemí Hinostroza, Jan Jacobs, Coralith García, Pablo Tsukayama

“…Lineage ST45 was the most prevalent and persisted for multiple years, followed by high-risk clones ST11 and ST147. The blaNDM-1 gene was carried almost exclusively by a Tn125-like transposon, similar to the one reported in previous studies from two Peruvian hospitals. …”
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High peripheral T cell diversity is associated with lower risk of toxicity and superior response to dual immune checkpoint inhibitor therapy in patients with metastatic NSCLC by Alexandre Reuben, Mehmet Altan, Latasha Little, Jianjun Zhang, Ajay Sheshadri, Hai T Tran, Mara B Antonoff, Stephen G Swisher, John V Heymach, Saumil Gandhi, Natalie Vokes, Ziyi Li, Ruoxing Li, Runzhe Chen, Joshua Baguley, Jefferson Sinson, Greg Lizee

“…Blood samples were systematically obtained at baseline (n=107), after 12 weeks of ipilimumab and nivolumab (n=91), and at the time of grade ≥2 irAEs (n=77). …”
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Evaluating the Adequacy of Central Line-Associated Bloodstream Infection As a Quality Measure: A Cross-Sectional Analysis at a Single Tertiary Care Center by Piyush Mathur, MD, FCCM, FASA, FAMIA, Amanda J. Naylor, MD, MPH, Moises Auron, MD, Jean Beresian, MD, Alexandra Tallman, BSN, RN, SANE-A, Allison Griffith, MSN, RN, CCRN, CPHQ, Kathleen Seasholtz, BSN, RN, HACP, Mariel Manlapaz, MD, Katherine Zacharyasz, MSN, RN, CPHQ, Reem Khatib, MD, MBA, FASA, Shreya Mishra, PhD, Kathryn Haller, PA, Thomas Fraser, MD, Katherine Holman, MD

“…Majority of the CLABSI, 77.5% (266), occurred in the ICU. Of the CLABSI analyzed, 31.5% (107) were classified as unrelated to the CVC; 25.0% (85) had an unclear source; 43% (148) were classified as CVC related. …”
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Comparing short‐term outcome after implantation of the HeartWare® HVAD® and the Abbott® HeartMate 3® by Rene Schramm, Armin Zittermann, Michiel Morshuis, Michael Schoenbrodt, Ellen vonRoessing, Vera vonDossow, Andreas Koster, Henrik Fox, Kavous Hakim‐Meibodi, Jan F. Gummert

“…During a median follow‐up of 15.3 months (range: 0–30 months), 23 (29.1%) and 19 (24.1%) patients died in the HVAD and HM3 groups, respectively, with a hazard ratio for mortality of 0.84 [95% confidence interval (CI): 0.46–1.54; P = 0.568]. Freedom from cerebrovascular events did not differ significantly between study groups, with a hazard ratio of 0.57 (95% CI: 0.23–1.45; P = 0.241). …”
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Length of stay after colorectal surgery in Italy: the gap between “fit for” and “actual” discharge in a prospective cohort of 4529 cases by Lorenzo Pandolfini, Duccio Conti, Piercarlo Ballo, Silvia Rollo, Alessandro Falsetto, Gian Matteo Paroli, Paolo Ciano, Michele Benedetti, Leonardo Antonio Montemurro, Giacomo Ruffo, Massimo Giuseppe Viola, Felice Borghi, Gianandrea Baldazzi, Massimo Basti, Pierluigi Marini, Mariano Fortunato Armellino, Vincenzo Bottino, Giovanni Ciaccio, Alessandro Carrara, Gianluca Guercioni, Marco Scatizzi, Marco Catarci, the Italian ColoRectal Anastomotic Leakage (iCral) study group

“…The median [IQR] LOS was 6 [4–8] days in the no-gap group (3,910 patients, 86.3%), significantly lower (p < .001) than 7 [6–10] days in the gap group (619 patients, 13.7%). …”
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A deep learning algorithm to generate synthetic computed tomography images for brain treatments from 0.35 T magnetic resonance imaging by Luca Vellini, Flaviovincenzo Quaranta, Sebastiano Menna, Elisa Pilloni, Francesco Catucci, Jacopo Lenkowicz, Claudio Votta, Michele Aquilano, Andrea D’Aviero, Martina Iezzi, Francesco Preziosi, Alessia Re, Althea Boschetti, Danila Piccari, Antonio Piras, Carmela Di Dio, Alessandro Bombini, Gian Carlo Mattiucci, Davide Cusumano

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Caracterización de la oferta de recursos forestales del partido de Balcarce, provincia de Buenos Aires by M. MÓNACO, P. LACLAU

“…La superficie de los polígonos digitalizados de montes comerciales totalizó 3.017 ha de distintas subclases. Al relacionarse con otros mapas del partido, se observaron patrones de distribución de los montes, algunos asociados a cursos de agua, topografía, super- ficie de lotes o proximidad a centros urbanos o a la red vial. …”
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Seasonal Trends, Profiles, and Exposure Risk of PM2.5-bound Bisphenol Analogs in Ambient Outdoor Air: A Study in Shanghai, China by Janvier Munyaneza, Fahim A. Qaraah, Qilong Jia, Hanting Cheng, Huajun Zhen, Guangli Xiu

“…The highest average concentrations (BPA: 3.47 ng m−3; BPF: 2.46 ng m−3; BPS: 0.58 ng m−3, and bisphenol AF (BPAF): 1.14 ng m−3) were found within samples collected in winter periods. …”
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Stem Cells and Platelet-Rich Plasma Enhance the Healing Process of Tendinitis in Mice by Rosangela Alquieri Fedato, Júlio César Francisco, Gabriel Sliva, Lúcia de Noronha, Márcia Olandoski, Jose Rocha Faria Neto, Priscila Elias Ferreira, Rossana Baggio Simeoni, Eltyeb Abdelwahid, Katherine Athayde Teixeira de Carvalho, Luiz César Guarita-Souza

“…This theoretical rationale for the belief that cell therapies can serve as viable alternatives to current treatments chronic fibrotic opens the door for opportunities to continue this research.…”
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Germline Single-Nucleotide Polymorphism <i>GFI1-36N</i> Causes Alterations in Mitochondrial Metabolism and Leads to Increased ROS-Mediated DNA Damage in a Murine Model of Human Acu... by Jan Vorwerk, Longlong Liu, Theresa Helene Stadler, Daria Frank, Helal Mohammed Mohammed Ahmed, Pradeep Kumar Patnana, Maxim Kebenko, Eva Dazert, Bertram Opalka, Nikolas von Bubnoff, Cyrus Khandanpour

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A novel arterial coupler with non-return snap-fit connection approach optimized arterial end-to-end anastomotic technique: An experimental study by Hong-Bo Guo, Mo-Fei Wang, Ren-Qi Yin, Kang-Kang Zhi

“…In animal studies, QAC-assisted arterial anastomosis has superior profiles compared to hand-sewn anastomosis in anastomotic time (7.80 ± 1.41 vs. 16.38 ± 1.04 min), clamp time (8.80 ± 1.41 vs. 14.14 ± 1.57 min), and total operation time (46.64 ± 2.38 vs. 51.96 ± 3.65 min). …”
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Long-term outcome in people who use drugs successfully treated for hepatitis C infection with glecaprevir/pibrentasvir by Shana Yi, David Truong, Brian Conway

“…In the GRAND PLAN, we documented sustained virological response post-treatment Week12 (SVR12) in 108/117 (92.3 %) individuals (108/111 (mITT) or 97.3 % of those reaching the SVR12 timepoint) receiving an 8-week course of glecaprevir/pibrentasvir (G/P), with almost all using fentanyl and over half being unstably housed. …”
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Polybrominated Dibenzo-p-dioxins/Furans (PBDD/Fs) and Diphenyl Ethers (PBDEs) in the Indoor and Outdoor of Gymnasiums by Ching-Kai Su, Jian-He Lu, How-Ran Chao, Wei-Hsiang Chang, Ming-Hsien Tsai, Chih-Lung Wang, I-Cheng Lu, Yu-Ting Chang, Hsiao-Chi Chuang, Wan-Nurdiyana-Wan Mansor, Yi-Chyun Hsu, Ying-I Tsai, Shang-Ming Ma

“…The results showed that indoor-dust, indoor PM2.5, and outdoor PM2.5 levels of PBDD/Fs were 37.8 ± 13.7 pg WHO2005-TEQ g–1 and 0.00650 ± 0.00340 and 0.00469 ± 0.00101 pg WHO2005-TEQ m–3, respectively, in the gyms, while for PBDEs, they were 2670 ± 2330 ng g–1 and 9.54 ± 4.68, and 8.27 ± 3.46 pg m–3. …”
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Identification of Nontuberculous Mycobacteria in Patients with Pulmonary Diseases in Gyeongnam, Korea, Using Multiplex PCR and Multigene Sequence-Based Analysis by Min-Jeong Kim, Kyu-Min Kim, Jeong-Ih Shin, Jong-Hun Ha, Dong-Hae Lee, Jeong-Gyu Choi, Jin-Sik Park, Jung-Hyun Byun, Jung-Wan Yoo, Seokyong Eum, Myunghwan Jung, Seung Chul Baik, Woo Kon Lee, Hyung Lyun Kang, Min-Kyoung Shin

“…Coinfection was identified in 7 (2.2%) samples. The sixteen samples not classified by two-step mPCR included 6 (1.9%) cases of M. chimaera, 4 (1.3%) M. gordonae, 1 (0.3%) M. colombiense, 1 (0.3%) M. mageritense, and 1 (0.3%) M. persicum identified by sequence analysis. …”
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Profiling Key Phytoconstituents in Screw-Pressed <i>Nigella</i> Solid Residue and Their Distribution in Products and Byproducts During Oil Processing by Parbat Raj Thani, Joel B. Johnson, Surya Bhattarai, Tieneke Trotter, Kerry Walsh, Daniel Broszczak, Mani Naiker

“…Notably, TPC, FRAP, and CUPRAC had high transfer rates into the solid residue (78.1–85.9%, 65.4–75.7%, and 84.5–90.4%, respectively), whereas TQ, SFA, MUFA, and PUFA showed lower transfer rates (15.9–19.3%, 7.5–8.9%, 12.0–18.3%, and 6.5–7.5%, respectively). …”
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The Prevalence of Celiac Disease-Specific Auto-Antibodies in Type 1 Diabetes in a Moroccan Population by Ider Oujamaa, Majda Sebbani, Lahcen Elmoumou, Aïcha Bourrahouate, Rabiy El Qadiry, Soufian El Moussaoui, Imane Ait Sab, Mohamed Sbihi, Laila Ennazk, Ghizlane El Mghari-Tabib, Nawal El Ansari, Hicham Baizri, Mohamed Amine, Brahim Admou

“…The other 2 cases had a biopsy-proven CD. Compared to seronegative patients, seropositive cases had a higher percentage of associated autoimmune disorders (16% vs. 2.4%, p=0.008), with a significant lower height Z-scores (median: −0.90 (−3.93 to 0.95) vs. −0.51 (−4.54 to 2.18), p=0.029) and a higher HbA1c level (median: 11.30% (7.31 to 16.00) vs. 9.30% (4.40 to17.31), p=0.022). …”
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Akkermansia muciniphila identified as key strain to alleviate gut barrier injury through Wnt signaling pathway by Xin Ma, Meng Li, Yuanyuan Zhang, Tingting Xu, Xinchen Zhou, Mengqi Qian, Zhiren Yang, Xinyan Han

“…We further investigated the alleviatory effects of these two strains on ETEC infection in the AIMD mice model, which revealed that A. muciniphila and B. fragilis relieved ETEC-induced intestinal inflammation by maintaining the proportion of Treg/Th17 cells and epithelial damage by moderately activating the Wnt/β-catenin signaling pathway, while the effect of A. muciniphila was better than B. fragilis. …”
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The role of point-of-care ultrasound in the assessment of schistosomiasis-induced liver fibrosis: A systematic scoping review. by Eloise S Ockenden, Sandrena Ruth Frischer, Huike Cheng, J Alison Noble, Goylette F Chami

“…Where ultrasound technology was specified, studies after 2000 were more likely to use convex transducers (43.4%; 33/76) than studies conducted before 2000 (32.7%; 16/49). Reporting on ultrasound-based hepatic diagnoses and their association with clinical severity was poor. …”
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Clinicopathological Significance of FOXO4 Expression and Correlation with Prx1 in Head and Neck Squamous Cell Carcinoma by Yunping Lu, Yajun Shen, Lingyu Li, Min Zhang, Min Wang, Lihua Ge, Jing Yang, Xiaofei Tang

“…The function of FOXO4 correlation with HNSCC prognosis was analyzed via ONCOMINE, UALCAN, Human Protein Atlas, and cBioPortal. The expression of FOXO4 was detected in Prx1 silenced CaL27 and SCC9 cell lines by Western blot. …”
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