The Impacts of SLC22A1 rs594709 and SLC47A1 rs2289669 Polymorphisms on Metformin Therapeutic Efficacy in Chinese Type 2 Diabetes Patients by Di Xiao, Yu Guo, Xi Li, Ji-Ye Yin, Wei Zheng, Xin-Wen Qiu, Ling Xiao, Rang-Ru Liu, Sai-Ying Wang, Wei-Jing Gong, Hong-Hao Zhou, Zhao-Qian Liu

“…The distributions of SLC22A1 rs594709 and SLC47A1 rs2289669 polymorphisms were determined in 267 T2DM patients and 182 healthy subjects. …”
Get full text

Impact of the level of physical activities on emotional exhaustion, depersonalization, lack of personal accomplishment and burnout among students in the city province of Kinshasa by Liny Enyuka Kila, Constant Nkıama, Dalmond Kambale Mutsopi, Siloé Ntumba Tshiyamba, Carel Busano Nduakulu, Godefroid Kusuayi Mabele

“…The moderate and high level of physical activity practice significantly reduces emotional exhaustion by -14 (30.08 ± 13.04 vs 16.10 ± 10.38; p < 0.001), depersonalization by -7 (12. 45 ± 6.42 vs 5.89 ± 5.99; p < 0.001), burnout of -17 (28.17 ± 10.05 vs 11.00 ± 8.47; p < 0.001) and increases the personal accomplishment of students of the faculty of medicine of +31 (42.00 ± 10.7 vs 11.00 ± 8.47; p < 0.002). …”
Get full text

Painting a portrait: Analysis of national health survey data for cancer genetic counseling by Monica H. Stamp, Ora K. Gordon, Christopher P. Childers, Kimberly K. Childers

“…After adjustment, however, only female sex (Odds Ratio [OR]: 1.78 [95% CI: 1.18‐2.67]) remained a significant predictor of genetic counseling among the affected. …”
Get full text

Annealing Study on Praseodymium-Doped Indium Zinc Oxide Thin-Film Transistors and Fabrication of Flexible Devices by Zhenyu Wu, Honglong Ning, Han Li, Xiaoqin Wei, Dongxiang Luo, Dong Yuan, Zhihao Liang, Guoping Su, Rihui Yao, Junbiao Peng

“…However, the μ-PCD test shows the 250 °C-annealed film obtains the least defects. And the PrIZO TFT annealed at 250 °C exhibited a desired performance with a saturation mobility (μ_sat) of 14.26 cm²·V⁻¹·s⁻¹, a subthreshold swing (SS) of 0.14 V·dec⁻¹, an interface trap density (D_it) of 3.17 × 10¹¹, an I_on/I_off ratio of 1.83 × 10⁸ and a threshold voltage (Vth) of −1.15 V. …”
Get full text

Implementation of prehospital point-of-care ultrasound using a novel continuous feedback approach in a UK helicopter emergency medical service by Salman Naeem, Shadman Aziz, Thomas Hirst, Johannes Strobel, Jamin M. Mulvey, Ailidh Lang, Jankee Patel, Alexander Smith, Ka Jun Cheng, Michael Palmer, Jonas Schlautmann, Michael D. Christian, Daniel Nevin

Subjects: “…PoCUS…”
Get full text

Traditional Chinese Mind and Body Exercises for Neck Pain: A Meta-Analysis of Randomized Controlled Trials by Yu-Hua Xie, Man-Xia Liao, Mao-Yuan Wang, W. C. Hewith A. Fernando, Yue-Ming Gu, Xue-Qiang Wang, Lin-Rong Liao

“…Compared with the control groups, TCMBE had no therapeutic advantage in improving pain intensity (visual analogue scale: mean difference (MD) = 1.8, 95% confidence interval (CI): −7.70 to 11.46, and P = 0.70); functional mobility (neck disability index: MD = 0.15, 95% CI: −6.37 to 6.66, and P = 0.96; neck pain and disability scale: MD = 1.31, 95% CI: −4.10 to 6.71, and P = 0.64); or 36-item short-form health survey (SF-36) scores for physical function (MD = 5.58, 95% CI: −8.03 to 19.18, and P = 0.42), general health (MD = 1.87, 95% CI: −4.99 to 8.72, and P = 0.59), body pain (MD = 2.26, 95% CI: −3.80 to 8.32, and P = 0.46), vitality (MD = 6.24, 95% CI: −1.49 to 13.98, and P = 0.11), social function (MD = 8.06, 95% CI: −4.85 to 20.98, and P = 0.22), role physical (MD = –1.46, 95% CI: −8.54 to 5.62, and P = 0.69), or role emotional (MD = 6.5, 95% CI: −3.45 to 16.45, and P = 0.2). …”
Get full text

The state of combined thoracoabdominal triple-organ transplantation in the United States by Emily G. Dunbar, BS, Ye In Christopher Kwon, BA, Matthew Ambrosio, MS, Inna F. Tchoukina, MD, Keyur B. Shah, MD, David A. Bruno, MD, Walker A. Julliard, MD, Josue Chery, MD, Vigneshwar Kasirajan, MD, Zubair A. Hashmi, MD

“…Recipient and donor characteristics and risk factors for mortality were analyzed using Cox regression hazard models. Recipient survival up to 10 years was analyzed using the Kaplan-Meier method. …”
Get full text

Potential of Pine Biochar to Mitigate Bacterial Hazards Present in Recycled Manure Solids from Dairy Cows by Ana José Pires, Ana Filipa Esteves, Gonçalo Pereira, Catarina Geraldes, Joana Fernandes Guerreiro, Raquel Abreu, Rita Magalhães, Lélia Chambel, Elisabete Silva, David Fangueiro, Manuela Oliveira, Ricardo Bexiga

“…The use of recycled manure solids (RMS) as cow bedding in dairy farms poses concerns due to its potential to harbor pathogenic and antimicrobial-resistant bacteria. …”
Get full text

Expansion and Assessment of a Web-Based 24-Hour Dietary Recall Tool, Foodbook24, for Use Among Diverse Populations Living in Ireland: Comparative Analysis by Grace Bennett, Shuhua Yang, Laura A Bardon, Claire M Timon, Eileen R Gibney

“…Only intakes of potatoes and potato dishes and nuts, herbs, and seeds significantly differed across methods of assessment, where correlations across these food groups were low (r=0.56 and r=0.47, respectively). The incidence of food omissions varied across samples, with Brazilian participants omitting a higher percentage of foods in self-administered recalls than other samples (6/25, 24% among the Brazilian vs 5/38, 13% among the Irish cohort). …”
Get full text

پهنه‌بندی خطر وقوع زمین‌لغزش با استفاده از مدل تحلیل سلسله مراتبی (AHP) و فن GIS (مطالعۀ موردی: شهرستان باغملک)... by مرتضی لجم اورک, زهرا پیری

Get full text

Modeling the determinants of attrition in a two-stage epilepsy prevalence survey in Nairobi using machine learning by Daniel M. Mwanga, Isaac C. Kipchirchir, George O. Muhua, Charles R. Newton, Damazo T. Kadengye, Abankwah Junior, Albert Akpalu, Arjune Sen, Bruno Mmbando, Charles R. Newton, Cynthia Sottie, Dan Bhwana, Daniel Mtai Mwanga, Damazo T. Kadengye, Daniel Nana Yaw, David McDaid, Dorcas Muli, Emmanuel Darkwa, Frederick Murunga Wekesah, Gershim Asiki, Gergana Manolova, Guillaume Pages, Helen Cross, Henrika Kimambo, Isolide S. Massawe, Josemir W. Sander, Mary Bitta, Mercy Atieno, Neerja Chowdhary, Patrick Adjei, Peter O. Otieno, Ryan Wagner, Richard Walker, Sabina Asiamah, Samuel Iddi, Simone Grassi, Sloan Mahone, Sonia Vallentin, Stella Waruingi, Symon Kariuki, Tarun Dua, Thomas Kwasa, Timothy Denison, Tony Godi, Vivian Mushi, William Matuja

“…Results: Random forest (AUC = 0.98, accuracy = 0.95, Brier score = 0.06, and F1 = 0.94), extreme gradient boost (XGB) (AUC = 0.96, accuracy = 0.91, Brier score = 0.08, F1 = 0.90) and support vector machine (SVM) (AUC = 0.93, accuracy = 0.93, Brier score = 0.07, F1 = 0.92) were the best performing models (base learners). …”
Get full text

Association between the composite dietary antioxidant index and non-alcoholic fatty liver disease: evidence from National Health and Nutrition Examination Survey 2005–2016 by Yidian Fu, Yidian Fu, Chao Jiang, Zonglin Li, Xiangyun Shi, Peiyuan Lv, Peiyuan Lv, Jingbo Zhang

“…Antioxidants from food can reduce NAFLD incidence, and the Composite Dietary Antioxidant Index (CDAI) measures total antioxidant capacity (TAC). …”
Get full text

Biological subphenotypes in patients hospitalized with suspected infection in Thailand: a secondary analysis of a prospective observational studyResearch in context by Prapassorn Poolchanuan, Taylor D. Coston, Viriya Hantrakun, Parinya Chamnan, Gumphol Wongsuvan, Pavan K. Bhatraju, Narisara Chantratita, Direk Limmathurotsakul, T. Eoin West, Shelton W. Wright

“…A parsimonious three-biomarker model identified subphenotypes in an internal validation cohort (LBP-1: area under the receiver operating curve [AUC] 0.96, 95% CI: 0.94–0.98; LBP-2: AUC 0.77, 95% CI 0.71–0.83; LBP-3: AUC 0.99, 95% CI 0.98–1.00). …”
Get full text

Comparative safety of the sodium glucose co-transporter 2 (SGLT2) inhibitors: a systematic review and meta-analysis by Kris Aubrey-Bassler, John-Michael Gamble, Jennifer R Donnan, Catherine A Grandy, Eugene Chibrikov, Carlo A Marra, Karissa Johnston, Michelle Swab, Jenna Hache, Daniel Curnew, Hai Nguyen

“…When compared with placebo, SGLT2 inhibitors were found to be significantly protective against AKI (RR=0.59; 95% CI 0.39 to 0.89; I2=0.0%), while no difference was found for DKA (RR 0.66; 95% CI 0.30 to 1.45, I2=0.0%), UTI (RR 1.02; 95% CI 0.95 to 1.09, I2=0.0%) or bone fracture (RR 0.87; 95% CI 0.69 to 1.09, I2=1.3%). …”
Get full text

Stimulation of DC-CIK with PADI4 Protein Can Significantly Elevate the Therapeutic Efficiency in Esophageal Cancer by Chunyan Liu, Yingying Zheng, Junyi Tang, Dawei Wang, Zhenshen Ma, Shutong Li, Xiaotian Chang

“…Induction of CIK cells with rPADI4-stimulated DCs elevated the cell proliferation by 50.3% and the ability of CIK cells to kill ECA-109 cells by 14.7% and suppressed tumor volume by 35.1% in the animal model. …”
Get full text

Probiotics supplementation for management of type II diabetes risk factors in adults with polycystic ovarian syndrome: a meta-analysis of randomized clinical trial by Chengcheng Zhang, Yingyue Sheng, Jinchi Jiang, Yuzheng Xue, Leilei Yu, Fengwei Tian, Jianxin Zhao, Hao Zhang, Jian Jin, Qixiao Zhai

“…An analysis of pooled extracted data revealed that supplementation with probiotics significantly decreased fasting blood glucose (FBG, n = 7; standardized mean difference (SMD) = −0.40; 95 % confidence interval (CI): −2.02, −0.02; P = 0.04) and insulin levels (n = 6; SMD = −0.57; 95 % CI: −0.89, −0.25; P = 0.0004) and the homeostatic model assessment of insulin resistance (n = 7; SMD = −0.64; 95 % CI: −0.96, −0.31; P = 0.0001) while increasing the quantitative insulin sensitivity check index (QUICKI, n = 5; SMD = 0.58; 95 % CI: 0.08, 1.09; P = 0.02) in patients with PCOS. …”
Get full text

Fermi Unassociated Sources in the MeerKAT Absorption Line Survey by Morgan Himes, Preshanth Jagannathan, Dale A. Frail, Frank Schinzel, Neeraj Gupta, S. A. Balashev, F. Combes, P. P. Deka, H.-R. Klöckner, E. Momjian, J. D. Wagenveld

“…The first MALS data release with a median rms noise of 22–25 μ Jy and 735,649 sources is a significant advance over past image-based searches with improvements in sensitivity, resolution, and bandwidth. …”
Get full text

Clinical Characteristics of Asymptomatic Patients with SARS-CoV-2 in Zhejiang: An Imperceptible Source of Infection by Wei Dai, Xinmiao Chen, Xiaoting Xu, Zhefeng Leng, Wenwen Yu, Hui Lin, Huiying Li, Jie Lin, Zhangwei Qiu, Yuanrong Dai

“…The proportion of patients received antiviral therapy was 45.5% in the asymptomatic group and 97.9% in the symptomatic group (p<0.001). The proportion of patients received oxygen therapy was 22.7% in the asymptomatic group and 99.1% in symptomatic patients (p<0.001). …”
Get full text

Chiral Pesticides in Soil and Water and Exchange with the Atmosphere by Terry F. Bidleman, Andi D. Leone, Renee L. Falconer, Tom Harner, Liisa M.M. Jantunen, Karin Wiberg, Paul A. Helm, Miriam L. Diamond, Binh Loo

“…., depletion of (+)trans-chlordane (TC) and (–)cis-chlordane (CC), and enrichment of the metabolite (+)heptachlor exo-epoxide (HEPX). …”
Get full text

Upper circumpolar deep water influences microbial functional gene composition and diversity along the southern Central Indian Ridge and eastern Southwest Indian Ridge by Sheryl Oliveira Fernandes, Dhiraj Paul, Surya Prakash Lankalapalli, Srinivas Rao Arvapalli, Vidya PJ, John Kurian Palayil

“…However, the depth-wise metabolic potential of microbial communities in hydrothermally influenced Central Indian Ridge (CIR) and Southwest Indian Ridge (SWIR) remains elusive. …”
Get full text