Exploring the role of inflammatory biomarkers in trigeminal neuralgia by Shenglong Lai, Haiyang Li, Yazhou Xing, Du Wu, Lin Wang, Qinghua Liang

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Corticosteroid Pulses for Hospitalized Patients with COVID-19: Effects on Mortality by Ivan Cusacovich, Álvaro Aparisi, Miguel Marcos, Cristina Ybarra-Falcón, Carolina Iglesias-Echevarria, Maria Lopez-Veloso, Julio Barraza-Vengoechea, Carlos Dueñas, Santiago Antonio Juarros Martínez, Beatriz Rodríguez-Alonso, José-Ángel Martín-Oterino, Miguel Montero-Baladia, Leticia Moralejo, David Andaluz-Ojeda, Roberto Gonzalez-Fuentes

“…Results. From 2933 patients, 257 fulfilled the inclusion and exclusion criteria. 124 patients were on corticosteroid pulses (250 mg of methylprednisolone for three days), and 133 were not. 30.3% (37/122) of patients died in the corticosteroid pulse group and 42.9% (57/133) in the nonexposed cohort. …”
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Tp53 determines the spatial dynamics of M1/M2 tumor-associated macrophages and M1-driven tumoricidal effects by Yi-Jing Hsiao, Min-Shu Hsieh, Gee-Chen Chang, Yin-Chen Hsu, Chia-Yu Wang, Yan-Ming Chen, Yi-Ling Chen, Pan-Chyr Yang, Sung-Liang Yu

“…This activation facilitates p53-STAT1 interactions, reduces the interaction between p53 and MDM2, and subsequently decreases p53 ubiquitination. M1 CM inhibited tumorigenesis, and silencing p53 reduced the anti-tumor efficacy of polyinosinic:polycytidylic acid (poly I:C) in vivo. …”
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Research on smoke diffusion and evacuation routes of mine fires with complex roadway networks by Menghui Xiao, Cuifeng Du, Yuan Wang, Jiuzhu Wang, Baomeng Chang

“…The results indicated that CO concentration significantly decreased at roadway corners, and both CO concentration and temperature gradually decreased with increasing depth. …”
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Family history of cardiovascular disease and death in patients with out-of-hospital cardiac arrest by Magnus Gylling, Johanna Krøll, Peder Emil Warming, Carolina Malta Hansen, Fredrik Folke, Steen M. Hansen, Lars Køber, Christian Torp-Pedersen, Rodrigue Garcia, Jacob Tfelt-Hansen, Peter E. Weeke

“…Results: Of 45,293 patients with OHCA 4,994, were eligible for inclusion (median age 50 years at OHCA, 76% male). Of these 47.7% had a family history of CVD (vs. 42.1% of controls), 68.2% of all-cause death (vs. 60.9%), 23% of premature death (vs. 15.8%) and 33.3% of cardiovascular death (vs. 27%) (p < 0.001 for all). …”
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Reverse Shoulder Arthroplasty Baseplate Stability Is Affected by Bone Density and the Type and Amount of Augmentation by Daniel Ritter, Patric Raiss, Patrick J. Denard, Brian C. Werner, Manuel Kistler, Celina Lesnicar, Micheal van der Merwe, Peter E. Müller, Matthias Woiczinski, Coen A. Wijdicks, Samuel Bachmaier

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An examination of ankle joint position sense, postural control and associated neuromuscular deficits in patients with plantar fasciitis: a cross-sectional analysis with advanced bi... by Shaker Hassan S. Alshehri, Mastour Saeed Alshahrani, Saeed Y. Al Adal, Faisal M. Alyazedi, Hani Hassan Alnakhli, Ravi Shankar Reddy

“…Pain catastrophizing was a significant predictor of AJPS in plantarflexion (β = -0.05, p = 0.001). Postural stability was negatively correlated with AJPS accuracy, particularly in mediolateral sway (r = -0.32, p = 0.037), while physical activity and quality of life had minimal effects. …”
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Global seroprevalence of Toxoplasma gondii in pregnant women: a systematic review and meta-analysis by Nader Salari, Avijeh Rahimi, Hosna Zarei, Amir Abdolmaleki, Shabnam Rasoulpoor, Shamarina Shohaimi, Masoud Mohammadi

“…Therefore, after the continent, the highest prevalence reported was reported in Africa with 46.8% (95% CI:39.5–54.3). Also, the lowest prevalence reported based on meta-analysis was in North America with 19.7% (95% CI:8.4–39.6) and Europe with 24.6% (95% CI:17.8–32.9). …”
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Genetic Polymorphisms of IL17 and Chagas Disease in the South and Southeast of Brazil by Pâmela Guimarães Reis, Christiane Maria Ayo, Luiz Carlos de Mattos, Cinara de Cássia Brandão de Mattos, Karina Mayumi Sakita, Amarilis Giaretta de Moraes, Larissa Pires Muller, Julimary Suematsu Aquino, Luciana Conci Macedo, Priscila Saamara Mazini, Ana Maria Sell, Divina Seila de Oliveira Marques, Reinaldo Bulgarelli Bestetti, Jeane Eliete Laguila Visentainer

“…The aim of this study was to investigate possible associations between genetic polymorphisms of IL17A G197A (rs2275913) and IL17F T7488C (rs763780) with Chagas Disease (CD) and/or the severity of left ventricular systolic dysfunction (LVSD) in patients with chronic Chagas cardiomyopathy (CCC). …”
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Lesion Topography and Clinical Features Associated With Respiratory Failure in Patients With Medullary Infarction by Na Zhao, Ran Liu, Yajing Zhang, Ling Ling, Chao Zhang, Ting Zhang, Wei Yue

“…Methods A total of 435 consecutive patients with MI within 7 days of onset in our institute were retrospectively enrolled from January 2017 to January 2024. …”
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Factors associated with occupational injuries among bricklayers and carpenters in Building Construction: insights from a mixed methods study in Osun State, Nigeria by Temitope Olumuyiwa Ojo, Adedeji Ayodeji Onayade, Nisha Naicker

“…Factors associated with OI among bricklayers included being aged 20–39 years (AOR:6.9, 95% CI:3.1–15.3) and 40–59 years (AOR:2.9, 95% CI:1.5–5.6), earning less than N50,000 (US$67) monthly (OR:2.3, 95% CI:1.2–4.7), earning N50,000-N99,000 (US$67-US$133) monthly (AOR:2.5, 95% CI: 1.2–5.2), and handling ≥ 200 kg per day at work (AOR:2.1, 95% CI:1.3–3.5). …”
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Arterial Stiffness Is More Associated with Albuminuria than Decreased Glomerular Filtration Rate in Patients with Type 2 Diabetes Mellitus: The REBOUND Study by Jong Ho Kim, Sang Soo Kim, In Joo Kim, Bo Hyun Kim, Ja Young Park, Chang Won Lee, Ji Hye Suk, Sun Hae Shin, Sung Pyo Son, Min Chul Kim, Jun Hyeob Ahn, Kwang Jae Lee, Min Jung Kwon, Soon Hee Lee, Jeong Hyun Park

“…A univariate analysis revealed that maximal baPWV was significantly associated with both the ACR (r=0.297, P<0.001) and eGFR (r=−0.220, P<0.001). A multivariate analysis adjusted for significant clinical variables and eGFR showed that baPWV remained significantly correlated with the ACR (r=0.150, P<0.001). …”
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Differences and analogies in thyroid cancer discovered incidentally or by thyroid-related screening: a multicenter study by Laura Croce, Rosaria Maddalena Ruggeri, Camilla Virili, Carlo Cappelli, Marsida Teliti, Pietro Costa, Spyridon Chytiris, Antonio Nicocia, Francesca Coperchini, Maria Flavia Bagaglini, Flavia Magri, Alfredo Campennì, Mario Rotondi

“…Measurements: Data on pre-surgery reasons leading to TC diagnosis, age, sex, BMI, presence of cardiometabolic comorbidities and non-thyroid cancer were collected. Results: Among the 327 enrolled subjects, the diagnosis of TC was prompted by thyroid-related reasons in 262 (80.1%, TD group) and incidental in 65 (19.9%, ID group). …”
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Extracellular matrix turnover in severe COVID-19 is reduced by corticosteroids by Janesh Pillay, Antine W. Flikweert, Matijs van Meurs, Marco J. Grootenboers, Simone van der Sar-van der Brugge, Peter H. J. van der Voort, Morten A. Karsdal, Jannie M. B. Sand, Diana J. Leeming, Janette K. Burgess, Jill Moser

“…Abstract Background Severe and critical COVID-19 is characterized by pulmonary viral infection with SARS-CoV-2 resulting in local and systemic inflammation. …”
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Game-thinking; utilizing serious games and gamification in nursing education – a systematic review and meta-analysis by Mats Nylén-Eriksen, Marko Stojiljkovic, Daniela Lillekroken, Katrin Lindeflaten, Elisabeth Hessevaagbakke, Tone Nygaard Flølo, Olav Johannes Hovland, Ada Marie Svarstad Solberg, Sylvia Hansen, Ann Kristin Bjørnnes, Christine Tørris

“…The meta-analysis suggested that game-thinking could be beneficial in nursing education, notably improving students’ academic achievement (Pooled ES = 0.99, [95%CI 0.53, 1.44]). The most significant effect of game-thinking on academic achievement was observed in the academic knowledge performance of nursing students (Pooled ES = 1.06, [95%CI 0.55, 1.57]), followed by academic skill performance (Pooled ES = 0.54, [95%CI 0.06, 1.03]). …”
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A Novel, Patient-Specific Mathematical Pathology Approach for Assessment of Surgical Volume: Application to Ductal Carcinoma in situ of The Breast by Mary E. Edgerton, Yao-Li Chuang, Paul Macklin, Wei Yang, Elaine L. Bearer, Vittorio Cristini

“…We then corroborated our hypothesis by comparing the predicted size of each tumor based on our model with the actual size of the pathological specimen after tumor excision (R2 = 0.74—0.88). In addition, for the 17 cases studied, both histological grade and mammography were not found to correlate with tumor size (R2 = 0.08—0.47). …”
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A Sustainable Approach: Repurposing Red Beetroot Peels for Innovative Meringue Products by Oana Emilia Constantin, Florina Stoica, Silvia Lazăr (Mistrianu), Doina Georgeta Andronoiu, Mihaela Turturică, Nicoleta Stănciuc, Roxana Nicoleta Rațu, Constantin Croitoru, Gabriela Râpeanu

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Korean patients with hereditary cancer: a prospective multicentre cohort study protocol exploring psychosocial and health outcomes by Boyoung Park, Sun-young Kong, Dongju Won, Jong Eun Park, Jun-Kyu Kim, Mi-Ae Jang, Jung-Sook Ha, Kyoung-Bo Kim

“…The collected data will be linked to secondary sources such as cancer registries and National Health Insurance Service data to provide a comprehensive analysis of the impact of hereditary cancer on health and survival.Ethics and dissemination The study protocol was approved by all the Ethics Committees: the National Cancer Center IRB (NCC2023-0179), the Samsung Medical Center IRB (SMC2023-09-057), the Yonsei University Health System, Severance Hospital IRB (4-2023-0627), the Hanyang University Guri Hospital IRB (GURI2023-08-021) and the Keimyung University IRB (DSMC IRB 2024-05-048). …”
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Efficacy and safety of first-line nivolumab plus ipilimumab treatment in elderly patients (aged ≥ 75 years) with non-small cell lung cancer by Satoshi Endo, Hisao Imai, Atsuto Mouri, Kasumi Tsukamoto, Kenji Masaki, Kosuke Hashimoto, Yu Miura, Ayako Shiono, Ou Yamaguchi, Junichi Nakagawa, Kyoichi Kaira, Kunihiko Kobayashi, Hiroshi Kagamu

“…Patients with and without AEs had a median PFS of 11.7 and 2.8 months, respectively. Similarly, the median OS of patients with and without AEs was 20.4 and 9.0 months, respectively. …”
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Optimizing Growth and Yield in Mulched Cotton Through Aerated Subsurface Drip Irrigation in Southern Xinjiang by Yuxi Zhang, Baolin Yao, Peining Niu, Zhu Zhu, Yan Mo, Fayong Li, Sanmin Sun

“…Importantly, aerating improved IWUE, achieving 1.72 kg/m³ in 2021 and 1.62 kg/m³ in 2022 for ASDI, versus 1.69 kg/m³ and 1.57 kg/m³ for unaerated subsurface drip irrigation, respectively. …”
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