Positive Associations between Adipocyte Fatty Acid-Binding Protein Level and Central Arterial Stiffness in Peritoneal Dialysis Patients by Cheng-Hao Sung, Bang-Gee Hsu, Jen-Pi Tasi, Chih-Hsien Wang, Chiu-Huang Kuo

“…Furthermore, serum A-FABP levels (β = 0.476, adjusted R2 change: 0.197, P < 0.001) were significantly positively correlated with cfPWV according to the multivariable forward stepwise linear regression analysis. …”
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Problem of pain in the USA: evaluating the generalisability of high-impact chronic pain models over time using National Health Interview Survey (NHIS) data by Sean Mackey, Titilola Falasinnu, Md Belal Hossain, Mohammad Ehsanul Karim, Kenneth Arnold Weber

“…De novo models based on 2021 data showed comparable discrimination (AUC: 0.86, 95% CI 0.85 to 0.87) but poorer calibration when validated against older datasets.Conclusion These findings underscore the potential of these models to guide personalised medicine strategies for HICP, aiming for more preventive rather than reactive healthcare. …”
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Dyslipidemia Impacts Cardiometabolic Health and CVD Risk in a Relatively Young Otherwise Healthy Population by Jillian M. Lang, Elena S. Shostak, William K. Quinn, Valerie D. Chervinskaya, Elisa Fioraso, Everett Smith, Christopher J. Kotarsky, Justin A. DeBlauw, Jennifer L. Lloyd, Stephen J. Ives

“…ABSTRACT Dyslipidemia, abnormal levels of lipids in the bloodstream, is associated with cardiovascular disease risk (CVD). The purpose of this study was to evaluate the effects of dyslipidemia on cardiometabolic health in relatively young, healthy adults. …”
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Preoperative Altered Spontaneous Brain Activity and Functional Connectivity Were Independent Risk Factors for Delayed Neurocognitive Recovery in Older Adults Undergoing Noncardiac... by Zhaoshun Jiang, Xixue Zhang, Yating Lv, Xiaodong Zheng, Huibiao Zhang, Xuelin Zhang, Chongyi Jiang, Guangwu Lin, Weidong Gu

“…The multivariate logistic regression analysis showed that higher preoperative spontaneous activity in the bilateral MCC was independently associated with a higher risk of DNR (OR=3.11, 95% CI, 1.30-7.45; P=0.011). A longer education duration (OR=0.57, 95% CI, 0.41-0.81; P=0.001) and higher preoperative FC between the bilateral MCC and left calcarine (OR=0.40, 95% CI, 0.18-0.92; P=0.031) were independently correlated with a lower risk of DNR. …”
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Influence of Sweetness and Ethanol Content on Mead Acceptability by Gomes Teresa, Dias Teresa, Cadavez Vasco, Verdial João, Morais Jorge Sá, Ramalhosa Elsa, Estevinho Letícia M.

“…Low concentrations of acetic acid were determined (0.46±0.08 and 0.57±0.09 g/L), avoiding the vinegar off-character. …”
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Structural Disruption of Cilia and Increased Cytoplasmic Tubulin in Biliary Atresia—An Exploratory Study Focusing on Early Postoperative Prognosis Following Portoenterostomy by Patrícia Quelhas, Rui Oliveira, Carlos Kieling, Sandra Vieira, Jorge dos Santos

“…While the PC ratio per biliary structure (cilia ratio status, CRs) was similar between BA patients and controls, PC length was decreased in BA patients. …”
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Exploring the Prognostic Role of Trop-2, CD47, and CD163 Expression Levels on Survival Outcomes in Patients with Triple-Negative Breast Cancer by Ramazan Oguz Yüceer, Sedanur Aydın, Iclal Gelir, Tulay Koc, Ersin Tuncer, Mahmut Ucar

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Gut Microbiota, Microinflammation, Metabolic Profile, and Zonulin Concentration in Obese and Normal Weight Subjects by Agnieszka Żak-Gołąb, Piotr Kocełak, Małgorzata Aptekorz, Maria Zientara, Łukasz Juszczyk, Gayane Martirosian, Jerzy Chudek, Magdalena Olszanecka-Glinianowicz

“…Additionally, plasma zonulin level was proportional to daily energy intake (r=0.27, P<0.05) and serum glucose concentration (r=0.18, P<0.05) and inversely proportional to diet protein percentage (r=-0.23, P<0.05). …”
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Pathogenicity of germline VHL variants is associated with renal cell carcinoma size in von Hippel-Lindau disease by Gustavo H. Mori, Gustavo F. C. Fagundes, Lucas S. Santana, Felipe Freitas-Castro, Ana Caroline F. Afonso, Delmar M. Lourenço Jr., Maria Adelaide A. Pereira, Fabio Y. Tanno, Victor Srougi, Jose L. Chambo, Mauricio D. Cordeiro, William C. Nahas, Ana O. Hoff, Maria Candida B. V. Fragoso, Berenice B. Mendonca, Ana Claudia Latronico, Madson Q. Almeida

“…In contrast, central nervous system (CNS) hemangioblastomas (HBs) (90.47% vs. 53.12%; p = 0.004), pancreatic cysts (76.19% vs. 28.12%; p = 0.001) and RCCs (57.14% vs. 12.5; p = 0.001) were more common in patients with non-missense VHL variants. …”
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Structural equation modeling of the impact of disease activity on inflammatory bowel disease control: the mediating roles of self-efficacy and self-management behaviors by Yongli Zhu, Ke Liu, Jinfeng Jiang, Xin Cheng, Hao Wang, Feiyang Long, Kang Li, Changping Mu, Lijun Cui

“…Drawing on the Common-Sense Model of Self-Regulation (CSM) and related research, this study investigates how IBD activity status influences disease control through both direct and indirect pathways. …”
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Methodological issues of retrospective surveys for measuring mortality of highly clustered diseases: case study of the 2014–16 Ebola outbreak in Bo District, Sierra Leone by Grazia Caleo, Kamalini Lokuge, Katina Kardamanidis, Jane Greig, Jaroslava Belava, Emer Kilbride, Alhaji Sayui Turay, Gbessay Saffa, Ronald Kremer, Francesco Grandesso, Kostas Danis, Armand Sprecher, Gian Luca Di Tanna, Holly Baker, Helen A. Weiss

“…DEFF for non-EVD-specific mortality was 1.87 in the rural area and 0.44 in the urban area. …”
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Roles of the <i>Sec2p</i> Gene in the Growth and Pathogenicity Regulation of <i>Aspergillus fumigatus</i> by Yuhuan Liu, Shumi Shang, Cong Liu, Yichen Liu, Keyang Xu, Dan He, Li Wang

“…Furthermore, this gene positively regulated the autophagy pathway and enhanced CWI pathway gene expression to respond to rapamycin-induced autophagy. …”
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Prevalence of Depression and Sleep Disorders in Patients on Dialysis: A Cross-Sectional Study in Qatar by Fadwa Al-Ali, Mostafa Elshirbeny, Abdullah Hamad, Ahmad Kaddourah, Tarek Ghonimi, Rania Ibrahim, Tarek Fouda

“…Patients with diabetes mellitus (DM) had significantly more prevalence of poor sleep (131 (88.5%)) than those without DM (81 (77.1%), p=0.01). More female patients had depression than male patients (52% vs. 25%, p<0.0001; odds ratio: 3.27 (95% confidence interval: 1.9–5.6), p<0.0001). …”
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Features and predictive value of 6-min walk test outcomes in interstitial lung disease: an observation study using wearable monitors by Jiaying Li, Xiaobing Wu, Xiaoyan Li, Miaozhen Deng, Xinyin Liang, Huiqun Wei

“…We found significant differences in 6MWD (F=2.44, p=0.033), SpO2 change (F=2.58, p=0.025), HR at 0 min (F=2.87, p=0.014), HR at end of 6 min (F=2.58, p=0.025) and HR zenith (F=2.64, p=0.022) between the subtypes of ILD.Conclusion This observation provided an important evidence regarding oxygen titration. …”
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Social-structural barriers to primary care among sex workers: findings from a community-based cohort in Vancouver, Canada (2014–2021) by Miriam T. H. Harris, Kate Shannon, Andrea Krüsi, Haoxuan Zhou, Shira M. Goldenberg

“…At first available observation, participants faced a high burden of sexually transmitted and blood-borne infections (STBBIs) (48.0%, 11.5%, and 10.4% were HCV, HIV, or STI seropositive, respectively), 56.8% were diagnosed with a mental health disorder, 8.1% had recently overdosed, and 14.7% were recently hospitalized. In multivariable GEE analysis, exposure to intimate partner violence was associated with reduced primary care use (Adjusted odds ratios (AOR) 0.63, 95% Confidence interval (CI): 0.49—0.82), and limited English fluency was marginally associated (AOR 0.76 CI: 0.51—1.14). …”
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Lack of Male-Female Differences in Disposition and Esterase Hydrolysis of Ramipril to Ramiprilat in Healthy Volunteers after a Single Oral Dose by Tom B. Vree, Erik Dammers, Ivan Ulc, Stefan Horkovics-Kovats, Miroslav Ryska, IJsbrand Merkx

“…The groups of female and male volunteers showed similar yields (AUCt = mg.h/L) of the metabolite ramiprilat (p = 0.37); however, females showed a higher AUCt/kg than males (p = 0.046). …”
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Identification of Crucial lncRNAs for Luminal A Breast Cancer through RNA Sequencing by Xinjian Jia, Hai Lei, Xuemei Jiang, Ying Yi, Xue Luo, Junyan Li, Yu Chen, Sha Liu, Chengcheng Yang

“…Several hub proteins were identified in the PPI network, including TUBB3, HIST2H3C, MCM2, MYOC, NEK2, LIPE, FN1, FOXJ1, S100A7, and DLK1. …”
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Efficacy and Safety of Cataract Surgery Combined with Ab Interno Canaloplasty and Micro-Trabecular Bypass Stent Surgery in Open-Angle Glaucoma by Porter MS, Flowers A, Wood BP, Gallardo MJ

“…In the uncontrolled group (n=27), baseline IOP and number of medications were 21.9± 3.1 and 1.9± 1.3 and reduced to 14.6± 4.2 (p=0.006) and 1.7± 1.6 (p=0.821) at 36 months postoperatively. …”
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Faktor-Faktor yang Berhubungan dengan Kejadian Obesitas pada Mahasiswa Fakultas Ilmu Kesehatan Universitas Pembangunan Nasional “Veteran” Jakarta by Fairy Amara Rahadian, Utami Wahyuningsih, Sintha Fransiske Simanungkalit

“…Data dikumpulkan menggunakan kuesioner dan pengukuran antropometri yang kemudian dianalisis menggunakan uji Chi-Square. Hasil: Hasil analisis statistik menunjukkan bahwa frekuensi konsumsi makanan manis memiliki p-value (0,111), frekuensi minuman manis (p-value=0,733), frekuensi makanan tinggi lemak (p-value=0,036), asupan manis (p-value=1,000), asupan tinggi lemak (p-value=0,426), asupan serat (p-value=0,819), perilaku emotional eating (p-value=0,057), external eating (p-value=0,871), aktivitas fisik (p-value=0,271), dan p-value tingkat stres (1,000). …”
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Assessment of phytochemical screening, antibacterial, analgesic, and antipyretic potentials of Litsea glutinosa (L.) leaves extracts in a mice model. by Zubair Khalid Labu, Samira Karim, Md Tarekur Rahman, Md Imran Hossain, Sarder Arifuzzaman, Md Shakil

“…Analgesic activity at 500 mg/kg, LG extract produced a 70% suppression of writhing in mice, which was statistically significant (p < 0.001) compared to standard morphine's (77.5%) inhibition. In antipyretic activity assay, the crude extract showed notable reduction in body temperature (36.17 ±  0.32 °C) at dose of 300 mg/kg-body weight, when the standard (at dose 100 mg/kg-body weight) exerted (36.32 ±  0.67 °C) after 3 h of administration. …”
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