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1841
Designing multivalent NiMn-based layered nanosheets with high specific surface area and abundant active sites for solid-state hydrogen storage in magnesium hydride
Published 2025-01-01“…With large specific surface area and abundant active sites, two-dimensional (2D) nanomaterials are promising catalysts for MgH2 via providing numerous pathways for the diffusion and dissociation of hydrogen. …”
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1842
The dual anti-inflammatory and anticoagulant effects of Jianpi Huashi Tongluo prescription on Rheumatoid Arthritis through inhibiting the activation of the PI3K/AKT signaling pathway
Published 2025-02-01“…In vitro co-culture model showed that XFC inhibited RA-related inflammatory responses and hypercoagulable states by suppressing the activation of the PI3K/AKT signaling pathway.ConclusionThis study demonstrates that XFC exerts its dual anti-inflammatory and anticoagulant effects, at least in part, by inhibiting the activation of the PI3K/AKT signaling pathway, providing potential insights into targeted therapy for RA.…”
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1843
Structural study, optical properties, thermal stability, and biological activity of a non-centrosymmetric hybrid compound 3,4-Diaminopyridinium perchlorate (3,4-DAPP)
Published 2025-03-01“…Finally, biological activity tests revealed that 3,4-DAPP exhibited moderate antibacterial activity, particularly against Bacillus cereus. …”
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1844
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1845
Asiaticoside Attenuates Chronic Restraint Stress-Induced Hippocampal CA1 Neuronal Ferroptosis via Activating BDNF/Nrf2/GPX4 Signaling Pathway
Published 2025-02-01“…Our research aims to elucidate the potential antidepressant mechanisms of asiaticoside, a bioactive compound known for its neuroprotective and immunomodulatory properties.Methods: The antidepressant-like properties of asiaticoside in a model of chronic restraint stress (CRS)-induced depression in mice, with a particular focus on its interaction with ferroptosis-related pathways.Results: The behavioral results revealed that asiaticoside significantly ameliorated CRS-induced depressive symptoms, as evidenced by increased sucrose preference and reduced immobility time. …”
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1846
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1847
Blue light irradiation combined with low-temperature storage further enhances postharvest quality of strawberries through improving antioxidant defense and cell wall metabolic activities
Published 2025-01-01“…Few studies have explored the impact of blue light-emitting diode (BL) irradiation combined with different storage temperatures on antioxidant defense and cell wall metabolic activities related to the quality deterioration of postharvest strawberries. …”
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1848
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1849
Active ingredients and mechanisms of peony seed blended oil in diabetes treatment using Kunming mice: Insights from GC–MS, network pharmacology, and experimental verification
Published 2025-02-01“…The results showed that the optimal blend ratio of peony seed oil to soybean and rapeseed oils was 60:27:11, which significantly inhibited α-amylase and α-glucosidase activities. Network pharmacology and molecular docking revealed that α-linolenic acid and linoleic acid are key active compounds, targeting PPARG and MAPK3, primarily through the PPAR and IL17 signaling pathways. …”
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1850
A comparative study of chemical composition, phenolic compound profile and antioxidant activity of wild grown, field and greenhouse cultivated Physalis (P. alkekengi and P. peruviana)
Published 2025-02-01“…Abstract Phytochemical properties and antioxidant activity of medicinal Physalis alkekengi fruit (wild and cultivated genotypes) and P. peruviana commercial species, were investigated (ten samples). …”
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1851
Metabolites induced by citrus tristeza virus and ‘Candidatus Liberibacter asiaticus’ influence the feeding behavior of Diaphorina citri: an electrical penetration graph and LC–MS/MS study
Published 2025-02-01“…The combined results are as follows: (1) The lowest number of metabolites were enriched in CTV-infected plants, which hardly influenced the feeding behavior of D. citri, suggesting that mild CTV strain (CT31) infection caused limited disorders in citrus plants compared with CLas infection; (2) Increased levels of L-arabinose and kaempferol in CTV-infected and CLas-CTV coinfected plants were suggested to contribute to increased penetration time during feeding of D. citri. …”
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1852
Influence of Altered Knee Angle on Electromyographic Activity of Hamstring Muscles Between Nordic Hamstring Exercise and Nordic Hamstring Exercise with Incline Slope Lower Leg Board
Published 2022-08-01“… # Purpose This study aimed to investigate the influence of changing muscle length on hamstring electromyographic activity during an isometric NHE, while maintaining an equal moment arm…”
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1853
HSRoadNet: Hard-Swish Activation Function and Improved Squeeze–Excitation Module Network for Road Extraction Using Satellite Remote Sensing Imagery
Published 2025-01-01Subjects: “…Activation function…”
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Physically Active Adults with Low Back Pain do not Demonstrate Altered Deadlift Mechanics: A Novel Application of Myotonometry to Estimate Inter-Muscular Load Sharing
Published 2024-01-01“…# Background Rehabilitation clinicians that work with physically active populations are challenged with how to safely return patients back to performing deadlift movements following low back injury. …”
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1856
Shramahara Mahakasya, a traditional polyherbal formulation, induces anti-anxiety activity in hippocampal neurons by effectuating SOD2-mediated protection against oxidative stress
Published 2025-02-01“…However, its mechanism of action remains largely unexplored. …”
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1857
Butylboronic acid promotes cell proliferation, alkaline phosphatase activity, and expression of GJA1, ALP, and NaBC1 in human dental pulp cells in vitro
Published 2025-02-01“…The objective of this study is to investigate the effects of n-butylboronic acid (n-BA) on the proliferative activity, alkaline phosphatase activity, expression of hard tissue formation related genes, ALP and GJA1, and boron transporter gene, NaBC1, in human dental pulp cells. …”
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Clofarabine induces tumor cell apoptosis, GSDME-related pyroptosis, and CD8+ T-cell antitumor activity via the non-canonical P53/STING pathway
Published 2025-02-01“…Most importantly, Clo administration dramatically increased the cytotoxic activity of CD8+ T cells in vitro and in vivo. Mechanistically, the administration of Clo induced the interaction of P53 with STING, which activated the non-canonical STING-NFκB pathway; consequently, NF-κB directly bound to the promoter regions of its target genes, including CCL5, CXCL10, HLAs and BAX. …”
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1860
FAM210B activates STAT1/IRF9/IFIT3 axis by upregulating IFN-α/β expression to impede the progression of lung adenocarcinoma
Published 2025-02-01“…Abstract FAM210B (family with sequence similarity 210 member B) is a novel protein that has been linked to tumor development. However, its role and underlying mechanisms in lung adenocarcinoma (LUAD) progression remain largely unexplored. …”
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