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1822
Microglia TRPC1 SUMOylation drives neuroinflammation after stroke by modulating NLRP3 activity via increasing TRPC1 interaction with ARRB2
Published 2025-03-01“…Microglial canonical transient receptor potential channel 1 (TRPC1) has been proposed to influence neuroinflammation after cerebral ischemia and reperfusion injury (CIRI), however, the underlying mechanism remains poorly understood. …”
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1823
Mycochemistry, antioxidant, anticancer activity, and molecular docking of compounds of F12 of ethyl acetate extract of Astraeus asiaticus with BcL2 and Caspase 3
Published 2025-02-01“…The column chromatography of AAEA extract was performed and the F12 fraction demonstrated the greatest radical scavenging activity with an EC50 of 25.65 ± 4.82 µg. mLˉ¹. Mycochemistry (GC and mass spectrum) analysis showed that F12 was a mixture of six important compounds like Hexadecanoic acid, 3,4,5,6 Tetramethyloctane, 9,12-Octadecadienoic acid, 9,12-Octadecadienoic acid, methyl ester, 1-cyclododecyne, cis-9,10-Epoxyoctadecan-1-ol. …”
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1824
NUAK1 acts as a novel regulator of PD-L1 via activating GSK-3β/β-catenin pathway in hepatocellular carcinoma
Published 2025-02-01“…Inhibition of GSK3β activity significantly promoted β-catenin expression and PD-L1 expression in HCC cells. …”
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1825
Pengujian Rule-Based pada Dataset Log Server Menggunakan Support Vector Machine Berbasis Linear Discriminat Analysis untuk Deteksi Malicious Activity
Published 2022-02-01“…From the information in the logs, it can be used for system security purposes, one of which is by performing analysis using data mining of client activities recorded on the server log. In addition, if there is a file uploaded by a user, it can also be linked in server log analysis in recognizing activity patterns and malicious files. …”
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1826
MsCL-P1: A multifunctional C-type lectin from largemouth bass (Micropterus salmoides) with broad microbe binding and agglutination activities
Published 2025-06-01Subjects: Get full text
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1827
Penerapan Algoritma Deep Learning Convolutional Neural Network Dalam Menentukan Kematangan Buah Jeruk Manis Berdasarkan Citra Red Green Blue (RGB)
Published 2023-02-01“…Pengamatan dengan cara ini memiliki beberapa kelemahan yaitu adanya keterbatasan visual manusia, di pengaruhi oleh kondisi psikis pengamatannya serta memakan waktu yang lama terutama bagi perkebunan besar. Untuk itu, diperlukan suatu algoritma untuk menentukan buah jeruk manis dengan sistem terkomputerisasi yang dibuat menggunakan algoritma Convolutional Neural Network (CNN) merupakan salah satu algoritma dari deep learning yang merupakan pengembangan dari Multilayer Percepton (MLP) yang mampu mengolah data dalam bentuk dua dimensi, misalnya gambar serta mampu melakukan klasifikasi pada citra dengan kelas–kelas yang lebih banyak atau besar. …”
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1828
Establishment of wetland conservation networks in response to climate change and anthropogenic activities: A case study from the Liaohe River Basin in Liaoning Province, China
Published 2025-02-01“…Wetlands are undergoing rapid transformations due to climate change and human activities, necessitating proactive conservation efforts. …”
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The ubiquitin-conjugating enzyme UBE2D maintains a youthful proteome and ensures protein quality control during aging by sustaining proteasome activity.
Published 2025-01-01“…Mechanistically, UBE2D/eff is necessary to maintain optimal proteasome function: UBE2D/eff knockdown reduces the proteolytic activity of the proteasome, and this is rescued by transgenic expression of human UBE2D2, an eff homolog. …”
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1830
Optimization of Soursop (Annona Muricata L.) Leaf Extract in Nanoemulgel And Antiacnes Activity Test Against Propionibacterium Acnes, Staphylococcus Aureus, Staphylococcus Epidermidis Bacteria.
Published 2024“…Soursop leaf extract (Annona muricata L.) has antibacterial activity with active components of alkaloids, flavonoids, steroids, and saponins. …”
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Noncoding RNAs in sepsis-associated acute liver injury: Roles, mechanisms, and therapeutic applications
Published 2025-02-01Subjects: Get full text
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Soma Linyit Kömürü, Külü Azaltılmış Soma Linyit Kömürü ve Kömür Karışımlarından Aktif Karbon Üretimi ve Karakterizasyonu
Published 2023-06-01Subjects: Get full text
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RETRACTED: LncRNA CCAT2 promotes the proliferation and metastasis of colorectal cancer through activation of the ERK and Wnt signaling pathways by regulating GNB2 expression
Published 2024-09-01“…Conclusion CCAT2 plays a crucial role in CRC progression by modulating the ERK and Wnt signaling pathways through its interaction with GNB2. These findings highlight the importance of CCAT2 as a key regulatory element in the mechanisms underlying CRC proliferation and metastasis.…”
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Antibacterial activity of 1 % Roselle flower nano-emulsion extract (Hibiscus sabdariffa) against peri-implantitis-related bacteria on orthodontic mini-implants: An in vitro study
Published 2025-01-01“…Roselle flowers (Hibiscus sabdariffa) possess beneficial active phytochemical substances, which may have potential as an OMI peri-implantitis alternative therapy. …”
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Preoperative evaluation of red blood cell distribution width as a promising biomarker for discriminating between benign and malignant breast tumors and assessing breast cancer activity
Published 2024-04-01“…The present study is not without limitations, and the authors suggest that a larger multicenter prospective study be conducted to further validate it’s efficacy over an extended duration.…”
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