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    Butyrate-engineered yeast activates Nppa and Sgcg genes and reduces radiation-induced heart damage via the gut-heart axis by Jiahao Wu, Kaihua Ji, Guangbo Kang, Manman Zhang, Jigang Wang, Lina Wang, Mengxue Gao, Xiaoxiao Jia, Xinran Lu, Yan Wang, Xinran Gao, Yufei Guo, Zhixin Zhu, Qinghua Wang, Zhenyu Zhao, Qiang Liu, He Huang

    Published 2025-03-01
    “…Mechanistically, engineered yeast enhanced taurine and nicotinamide metabolism by increasing the relative abundance of Akkermansia and Lachnospiraceae_NK4A136; then, yeast modulated cardiac function by activating the Sgcg and Nppa genes to attenuate cardiac damage induced by abdominal irradiation. …”
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  5. 1605
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    Elucidating the metabolic mechanisms and active constituents of ZuoGui Wan in combatting postmenopausal osteoporosis: A metabolomics and network pharmacology approach by Yanchen Feng, KaiKai Shi, Dingming Li, Shunzhi Yang, Xue Dang, Jinyao Li, Yan Chen, Jianping Yao, Yunke Zhang, Lu Sun, Feixiang Liu

    Published 2025-02-01
    “…ZuoGui Wan (ZGW) can effectively ameliorate bone loss associated with decreased estrogen levels, the metabolic mechanisms and active ingredients involved remain unclear. Method: We evaluated the efficacy of ZGW on bone loss in ovariectomized (OVX) rats. …”
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    Ddx21 mutant peptide is an effective neoantigen in prophylactic lung cancer vaccines and activates long-term anti-tumor immunity by Zhe Zhang, Yimeng Xia, Yimeng Xia, Zhihong Wang, Yaxing Sun, Dan Pu, Yijia He, Ruixian Liu, Yanru Zhang, Yan Liu, Junzhi Yu, Shiyang Ning, Baisui Feng, Yaohe Wang, Na Wang

    Published 2025-02-01
    “…IntroductionLung cancer is the leading cause of cancer-related death worldwide, and its morbidity and mortality are increasing. Although low-dose CT lung cancer screening has been shown to reduce lung cancer mortality, its adoption rate is limited and the pace of its promotion is slow, highlighting the urgent need for more effective prevention measures. …”
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  10. 1610

    Analisis Perbandingan Algoritma Machine Learning dan Deep Learning untuk Klasifikasi Citra Sistem Isyarat Bahasa Indonesia (SIBI) by Mohammad Farid Naufal, Selvia Ferdiana Kusuma

    Published 2023-08-01
    “…Computer vision adalah sebuah Teknik yang digunakan komputer untuk melakukan klasifikasi citra. Computer vision membantu pengenalan citra SIBI secara otomatis sehingga memudahkan orang normal berkomunikasi dengan orang tuli atau bisu. …”
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    Return to sports activities following posterior scoliosis correction and instrumented fusion for adolescent idiopathic scoliosis and its correlation to Lenke classification by Tahir Khaleeq, Ibrahim Jaly, Matthew Lea, Devi Prakash Tokala, Neil Davidson, Jayesh Trivedi, Sudarshan Munigangaiah

    Published 2024-12-01
    “…Introduction: There is a paucity of information or guidelines regarding return to sports activities after posterior scoliosis surgery for adolescent idiopathic scoliosis (AIS). …”
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  13. 1613

    Midazolam nasal spray to treat intermittent, stereotypic episodes of frequent seizure activity: pharmacology and clinical role, a comprehensive review by Elyse M. Cornett, Meskerem A. Nemomsa, Bailey Turbeville, Matthew A. Busby, Jessica S. Kaye, Aaron J. Kaye, JooHee Choi, Giovanni F. Ramírez, Giustino Varrassi, Adam M. Kaye, Alan D. Kaye, James Wilson, Latha Ganti

    Published 2022-10-01
    “…An intranasal formulation of midazolam, Nayzilam, has been FDA-approved to treat intermittent, stereotypic episodes of frequent seizure activity. Nayzilam is easy to administer and can quickly treat seizures that occur outside of the hospital. …”
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  14. 1614

    Platelet-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio associated with disease activity in patients with Takayasu’s arteritis: a case-control study by Juan Du, Lili Pan, Taotao Li, Hua Liao

    Published 2017-05-01
    “…A PLR level of 183.39 was shown to be the predictive cut-off value for TAK (sensitivity 37.8%, specificity 93.0%, area under the curve (AUC)=0.691). …”
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  15. 1615

    The Effect of a Novel Training Program to Improve Trunk Stability Push Up Performance in Active Females: A Pilot Study by Kate Schwartzkopf-Phifer, Suzanne Leach, Katie Whetstone, Kevin Brown, Kyle Matsel

    Published 2021-10-01
    “…Conclusion: The results of this study indicate that a multiplanar exercise approach, combining anti-extension and anti-rotation training, was beneficial for inducing trunk stability improvements in some active females. # Level of Evidence 2b…”
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    Mesenchymal stem cells from perinatal tissues promote diabetic wound healing via PI3K/AKT activation by Jiawei Huang, Qingwen Deng, Lai Ling Tsang, Guozhu Chang, Jinghui Guo, Ye Chun Ruan, Chi Chiu Wang, Gang Li, Hon Fai Chan, Xiaohu Zhang, Xiaohua Jiang

    Published 2025-02-01
    “…Conclusions MSCs From perinatal tissues particularly hUCMSCs and hCVMSCs significantly enhance diabetic wound healing through PI3K/AKT pathway activation while hDCMSCs exhibited weaker efficacy. …”
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    UN PERSA ENTRE LOS SOCRÁTICOS LA FIGURA DE CIRO Y LA CIROPEDIA EN ANTÍSTENES Y PLATÓN by RODRIGO ILLARRAGA

    Published 2020-01-01
    “…En este trabajo nos proponemos mostrar cómo, contra esa posible concepción, la figura de Ciro goza de una destacada presencia en el grupo socrático, en particular, para Antístenes y Platón. …”
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