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  1. 10021
    AKT1-Mediated NOTCH1 phosphorylation promotes gastric cancer progression via targeted regulation of IRS-1 transcription

    AKT1-Mediated NOTCH1 phosphorylation promotes gastric cancer progression via targeted regulation of IRS-1 transcription by Lingshan Zhou, Yuan Yang, Qian Qiao, Yingying Mi, Yuling Gan, Ya Zheng, Yuping Wang, Min Liu, Yongning Zhou

    Published 2024-12-01
    “…Results AKT1 was found to induce phosphorylation of Notch1 at the S2183 site in GC, subsequently altering the subcellular localization of Notch1-IC and promoting its nuclear translocation. …”
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  2. 10022
    Radiation dose and fraction in immunotherapy: one-size regimen does not fit all settings, so how does one choose?

    Radiation dose and fraction in immunotherapy: one-size regimen does not fit all settings, so how does one choose? by Marka Crittenden, Sandra Demaria, C Norman Coleman, Jonathan Schoenfeld, Arta Monjazeb, Samir Khleif, Seema Gupta, Andrew Sikora, Zachary Morris, Chandan Guha, Stephen Shiao, Silvia Chiara Formenti, Bhadrasain Vikram, Mansoor M Ahmed

    Published 2021-04-01
    “…Other novel delivery options may also affect immune responses, including T-cell activation and tumor-antigen presentation changes. However, there is limited understanding of the immunological impact of hypofractionated and unique multifractionated radiotherapy regimens, as these observations are relatively recent. …”
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  3. 10023
    Malignant phyllodes tumors with sarcomatous components: A histopathologic and molecular study

    Malignant phyllodes tumors with sarcomatous components: A histopathologic and molecular study by Ting Lei, Yunjie Song, Zhiyi Shen, Yongqiang Shi, Cunyan Xia, Xu Deng, Wenyue Da, Yan Peng, Qing Li

    Published 2025-03-01
    “…Conclusions: The presence of an osteosarcoma component may serve as an indicator for unfavorable prognosis. Activating mutations in TP53 have been identified in these tumors. …”
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  4. 10024
    A CRISPR/Cas12a electrochemical biosensing to detect pig mtDNA D-loop for ensuring food authenticity

    A CRISPR/Cas12a electrochemical biosensing to detect pig mtDNA D-loop for ensuring food authenticity by Muhammad Ihda H.L. Zein, Clianta Yudin Kharismasari, Ari Hardianto, Salma Nur Zakiyyah, Riezki Amalia, Mehmet Ozsoz, Mara Mirasoli, Irkham, Yeni Wahyuni Hartati

    Published 2025-02-01
    “…A CRISPR/Cas12a-based electrochemical biosensor has garnered attention for its rapidity, portability, high sensitivity, and specificity, leveraging trans-cleavage activity for precise detection. …”
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  5. 10025
    Youth experiencing homelessness at risk for suicide: psychosocial risk factors and service use patterns

    Youth experiencing homelessness at risk for suicide: psychosocial risk factors and service use patterns by Laura J. Chavez, Kelly J. Kelleher, Alicia Bunger, Xin Feng, Margaret Fitzpatrick, Jodi L. Ford, Allen B. Mallory, Arielle H. Sheftall, Tansel Yilmazer, Alexis Pizzulo, Jesse L. Hawke, Mattina A. Davenport, Natasha Slesnick

    Published 2025-02-01
    “…Given that the use of medical and mental health care is low among this population, more active outreach strategies may be warranted to deliver prevention interventions.…”
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  6. 10026
    Classification of risk for transmission of vaccine-preventable diseases in Brazilian municipalities: comparative analysis before and after the national movement for vaccination and multivaccination proposed by the Ministry of Health as of 2023

    Classification of risk for transmission of vaccine-preventable diseases in Brazilian municipalities: comparative analysis before and after the national movement for vaccination and... by Ana Catarina de Melo Araújo, Thales Philipe Rodrigues da Silva, Janaina Fonseca Almeida Souza, Krishna Mara Rodrigues Freire, Fernanda Penido Matozinhos, Eder Gatti Fernandes

    Published 2025-02-01
    “…Conclusion The study concludes that VC surveillance, in conjunction with the Microplanning for High-Quality Vaccination Activities methodology developed by the Ministry of Health in 2023, played a crucial role in resuming immunization efforts that had been hindered by science denialism and the COVID-19 pandemic.…”
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  7. 10027
    Growth of the prefrontal cortical glioblastoma altered cognitive and emotional behaviors via mediating miRNAs and GABA-A receptor signaling pathways in rats

    Growth of the prefrontal cortical glioblastoma altered cognitive and emotional behaviors via mediating miRNAs and GABA-A receptor signaling pathways in rats by Sepide Nateghi, Ameneh Rezayof, Fatemeh Kouhkan, Ladan Delphi, Yavar Bagheri Davisaraei, Fatemeh Rostami, Fatemeh Tirgar, Houri Sepehri

    Published 2025-02-01
    “…The present study investigated the impact of GABAergic signaling and miRNA expression on glioblastoma multiforme (GBM) growth within the medial prefrontal cortex (mPFC) and its associated cognitive and emotional impairments. …”
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  8. 10028
    Oridonin: A natural terpenoid having the potential to modulate apoptosis and survival signaling in cancer

    Oridonin: A natural terpenoid having the potential to modulate apoptosis and survival signaling in cancer by Abhishek Chauhan, Hemant Joshi, Divya Kandari, Diwakar Aggarwal, Ritu Chauhan, Hardeep Singh Tuli, Arpit Mehrotra, Abhilasha Sood, Ujjawal Sharma, Darin Mansor Mathkor, Shafiul Haque, Naveen Chandra Joshi, Laurent Dufossé

    Published 2025-02-01
    “…Background: Oridonin, a diterpenoid lactone derived from medicinal plants, has drawn considerable attention due to its therapeutic potential, particularly its anticancer properties. …”
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  9. 10029
    Phase 1 study of safety, tolerability, and efficacy of intradermal DNA vaccine ASP2390 in adults allergic to house dust mites

    Phase 1 study of safety, tolerability, and efficacy of intradermal DNA vaccine ASP2390 in adults allergic to house dust mites by Thomas Kayser, MD, BS, Ronald Smulders, MD, PhD, Tomohiro Kusawake, PhD, Erik Wambre, PhD, Gurunadh R. Chichili, PhD, Mary B. Blauwet, DrPH, Anna Spence, MS, Melanie Patton, BS, Rima Tabash, PhD, Hannah A. DeBerg, PhD, Sugandhika Khosa, MS, Philipp Badorrek, MD, Jens M. Hohlfeld, MD, Brian C. Ferslew, PharmD, PhD

    Published 2025-05-01
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  10. 10030
    BAFF and APRIL immunotherapy following Bacille Calmette-Guérin vaccination enhances protection against pulmonary tuberculosis in mice

    BAFF and APRIL immunotherapy following Bacille Calmette-Guérin vaccination enhances protection against pulmonary tuberculosis in mice by Min Xie, Chen-Yu Tsai, Joshua Woo, Frank Nuritdinov, Melissa Cristaldo, Narineh M. Odjourian, Rosleine Antilus-Sainte, Maureen Dougher, Martin Gengenbacher, Martin Gengenbacher

    Published 2025-02-01
    “…We have previously shown that unconventional B cell subsets play a role in tuberculosis control.MethodsHigh-dimensional flow cytometry and multiplex cytokine analysis were employed to investigate the effects of immunotherapy on BCG-vaccinated mice in an Mtb challenge model.ResultsIn this study, we investigate the potential of recombinant cytokines targeting B cells – B-cell activating factor (BAFF) and A proliferation-inducing ligand (APRIL) – to modulate BCG immunity and improve protection in mice. …”
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  11. 10031
    Toxicological effects of the environmental pollutant perfluoronanoic acid on the ground-dwelling arthropod Solenopsis invicta

    Toxicological effects of the environmental pollutant perfluoronanoic acid on the ground-dwelling arthropod Solenopsis invicta by Wenxuan Wang, Mingrong Liang, Yangting Ou, Xiangrui Wang, Yunbo Song, Huimei Chen, Jingxin Hong, Yuling Liang, Yongyue Lu

    Published 2025-01-01
    “…Elevated superoxide dismutase (SOD) and catalase (CAT) activities at higher PFNA concentrations indicated oxidative stress in RIFAs. …”
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  12. 10032
    Territorios rurales en transformación: desafíos y oportunidades frente al reto de la despoblación

    Territorios rurales en transformación: desafíos y oportunidades frente al reto de la despoblación by Néstor Vercher

    Published 2025-02-01
    “…Small orchards along the riverbanks maintain some activity, but the future of the sector depends on their capacity to adapt and revalue. …”
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  13. 10033
    Territorios rurales en transformación: desafíos y oportunidades frente al reto de la despoblación

    Territorios rurales en transformación: desafíos y oportunidades frente al reto de la despoblación by Néstor Vercher

    Published 2025-02-01
    “…Small orchards along the riverbanks maintain some activity, but the future of the sector depends on their capacity to adapt and revalue. …”
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  14. 10034
    WRF-Chem simulations of snow nitrate and other physicochemical properties in northern China

    WRF-Chem simulations of snow nitrate and other physicochemical properties in northern China by X. Wang, X. Wang, T. Che, T. Che, X. Ruan, S. Yue, S. Yue, J. Wang, J. Wang, C. Zhao, C. Zhao, C. Zhao, L. Geng, L. Geng, L. Geng

    Published 2025-02-01
    “…The model results show an underestimation especially in regions closes to large cities in northeastern China, most likely due to the underestimation of NO<span class="inline-formula"><sub><i>x</i></sub></span> emissions in these regions. …”
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  15. 10035
    Basics Fashion Design 10 , Jewellery Design : From Fashion to Fine Jewellery /

    Basics Fashion Design 10 , Jewellery Design : From Fashion to Fine Jewellery / by Galton, Elizabeth (Jewellery designer)

    Published 2012
    Table of Contents: “…A brief history of jewellery : The origins of Jewellery ; Jewellery through the ages ; Interview : Anne Kazuro-Guionnet ; Project : Researching references -- Jewellery styles : Jewellery categories ; Catwalk jewellery ; Fine jewellery ; Fashion jewellery ; Interview : Katie Hillier ; Interview : Lara Bohinc ; Ethical practice ; Case study : Ethical design ; Interview : Stephen Webster ; Projects : The customer -- Essential research : Sources of inspiration ; Trend forecasting ; Case study : Using trend research ; Research practices ; Customer research ; Interview : Shaun Leane ; Project : Creating a moodboard -- Design creation : The designer's brief ; Designing from your research ; Computer-aided design (CAD) ; Case study : Head of design ; Designing a balanced collection ; Interview : Maeve Gillies ; Project : Planning and recording your work -- Design development and realization : The development team ; Interview : Theo Fennell ; Materials and sourcing ; Pricing designs ; Sampling ; Case study : Production development ; Case study : Collections management ; Interview : Kasia Piechocka ; Project : Design realization -- Marketing : Creating a lookbook ; Portfolio ; Photographing designs ; Branding ; Communications ; Case study : PR consultant and writer ; Project : Creating a lookbook -- A career in jewellery : Training ; Contemporary designer ; Case study : Brand designer ; Design consultancy ; Interview Erickson Beamon ; Interview : Nadja Swarovski ; Portfolios and CV presentation ; Conclusion -- Glossary.…”
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  16. 10036
    Children's intonation : a framework for practice and research /

    Children's intonation : a framework for practice and research / by Wells, Bill (Clinical linguistics)

    Published 2016
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  17. 10037
    Seismic microzonation studies in the Southern part of Progo River, special Region of Yogyakarta, Indonesia

    Seismic microzonation studies in the Southern part of Progo River, special Region of Yogyakarta, Indonesia by Ghina Bani Azifah, Teuku Faisal Fathani, Hendy Setiawan

    Published 2025-02-01
    “…Due to the high intensity of seismic activities, it is essential to perform seismic hazard analysis by considering local site effects. …”
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  18. 10038
    Astaxanthin-loaded brain-permeable liposomes for Parkinson’s disease treatment via antioxidant and anti-inflammatory responses

    Astaxanthin-loaded brain-permeable liposomes for Parkinson’s disease treatment via antioxidant and anti-inflammatory responses by Thai-Duong Nguyen, Shristi Khanal, Eunhee Lee, Jinsol Choi, Ganesh Bohara, Nikesh Rimal, Dong-Young Choi, Soyeun Park

    Published 2025-02-01
    “…Astaxanthin is an antioxidant and anti-inflammatory agent; however, its high susceptibility to oxidative degradation and low aqueous solubility limit its therapeutic efficacy. …”
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  19. 10039
    Recommender Systems for Unified Modeling Language and Vice Versa&#x2014;A Systematic Literature Review

    Recommender Systems for Unified Modeling Language and Vice Versa&#x2014;A Systematic Literature Review by Elaheh Azadi Marand, Amir Sheikhahmadi, Moharram Challenger, Parham Moradi, Alireza Khalilipour

    Published 2025-01-01
    “…Additionally, these systems are extensively employed to facilitate software engineering activities, including modeling. Modeling environments are enriched with RSs that assist in building models by providing recommendations based on previous solutions to similar problems within the same domain. …”
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  20. 10040
    The Impact of Exposure to Indoor Pollutants on Allergy and Lung Inflammation among School Children in Selangor, Malaysia: An Evaluation Using Factor Analysis

    The Impact of Exposure to Indoor Pollutants on Allergy and Lung Inflammation among School Children in Selangor, Malaysia: An Evaluation Using Factor Analysis by Khairul Nizam Mohd Isa, Zailina Hashim, Juliana Jalaludin, Dan Norbäck, Mohammed Abdulrazzaq Jabbar, Jamal Hisham Hashim

    Published 2020-08-01
    “…There was a significant association between exposure to PM10 (OR = 2.66, 95% CI: 1.33−5.30) with skin allergy symptoms in the past 12 months. …”
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