Long-term exposure to fine particulate matter components with obesity in children and adolescents in China: The age-sex disparities and key effect modifiers by Jinling Wang, Xinyi Li, Guannan Bai, Rachel Huxley, Kejia Hu, Jinna Yuan, Xuelian Zhou, Xiaochi Zhang, Ke Huang, Guanping Dong, Wei Wu, Bingyan Cao, Rongxiu Zheng, Chunlin Wang, Haiyan Wei, Yan Liang, Hui Yao, Feihong Luo, Pin Li, Zhe Su, Ruimin Chen, Shaoke Chen, Jingsi Luo, Hongwei Du, Mireguli. Maimaiti, Jianwei Zhang, Yu Yang, Min Zhu, Qi Zhao, Junfen Fu

“…The odds ratio of childhood obesity was 1.28 (95 %CI: 1.15–1.43) for per interquartile range increase in PM2.5, with organic matter identified as the key contributor. …”
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Typical and atypical metabolic characteristics of three iridaceae isoflavone components: in vitro and in silico studies by Jifeng Gu, Jifeng Gu, Huishan Zhang, Mei Wang, Yuyang Zhou, Yuyang Zhou, Zhipeng Deng, Rong Shi

“…DC (Chinese name Shegan) has been widely used because of its pharmacological activity and remarkable therapeutic effects in sore throat. …”
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Distribution Characteristics of Nutrients and Eutrophication Assessment in Yueqing Bay by YAO Kaixue, YIN Rui, WANG Yang, CHEN Feng, LI Zhenhua

“…Based on the Marine environment monitoring data of Yueqing Bay in spring, summer, autumn and winter from 2018 to 2019, the spatial and temporal distribution characteristics of nutrient salts (dissolved inorganic nitrogen, DIN) and active phosphate (DIP) in the sea were analyzed, and the pollution degree, eutrophication degree and nutrient structure of the sea area were evaluated by single factor index method, eutrophication index method and potential eutrophication model. …”
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Skin autofluorescence as part of the comprehensive assessment of clinical and metabolic status of patients with end-stage chronic kidney disease by Darya Yu. Konovalova, Peter A. Lebedev, Olga V. Ushakova, Elena E. Potyakina, Dmitriy V. Kornilin, Vladimir N. Grishanov, Marina V. Komarova

“…Furthermore, highly significant direct correlations with left ventricular hypertrophy and its negative ejection fraction were established in this group. …”
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Gravity-based microfiltration reveals unexpected prevalence of circulating tumor cell clusters in ovarian and colorectal cancer by Anne Meunier, Javier Alejandro Hernández-Castro, Nicholas Chahley, Laudine Communal, Sara Kheireddine, Newsha Koushki, Nadia Davoudvandi, Sara Al Habyan, Benjamin Péant, Anthoula Lazaris, Andy Ng, Teodor Veres, Luke McCaffrey, Diane Provencher, Peter Metrakos, Anne-Marie Mes-Masson, David Juncker

“…Optimal flow rate and pore size for cCTC isolation are determined by GµF of cultured ovarian single cells and cell clusters spiked in healthy blood. …”
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Characterization and genomic analysis of a Herelleviridae bacteriophage UHP46 infecting mastitis-causing Staphylococcus aureus by Sara Najeeb, Imran Khan, Javed Muhammad, Muhammad Jahangir, Iqbal Ahmad Alvi, Anza Abbas, Aman Ullah, Arif Ullah, Wajiha Sajjad, Hashir Khan, Amjad Khan, Amjad Khan

“…One-step growth curve analysis indicated latent period of approximately 20 mins and burst size of about 27 progeny/cell. …”
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Advanced analysis of soil pollution in southwestern Ghana using Variational Autoencoders (VAE) and positive matrix factorization (PMF) by Raymond Webrah Kazapoe, Daniel Kwayisi, Seidu Alidu, Samuel Dzidefo Sagoe, Aliyu Ohiani Umaru, Ebenezer Ebo Yahans Amuah, Millicent Obeng Addai, Obed Fiifi Fynn

“…As (9.68 mg/L), and Pb (7.43 mg/L) reported elevated levels across the area linked to mining activities. The PTEs displayed a decreasing trend in the order Ba > Cr > V > Zn > Cu > Ni > As > Pb > Co. …”
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The characteristics of dermatology inpatients seen at the quaternary Inkosi Albert Luthuli Central Hospital in Durban, South Africa, over a 5-year period – 2015 - 2020 by L Mthembu, J T Masuka, K Duze, A Mosam

“…However, dermatology consultation services have remained active, offering care to patients admitted for non-cutaneous indications by other specialties. …”
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Familial Hypercholesterolemia: Genetics, Symptoms, Diagnosis and Treatment - A Literature Overview by Maciej Rutkiewicz, Sabina Przygodzka, Katarzyna Gadżała, Karolina Garbino, Katarzyna Brudniak, Antoni Szuścik, Magdalena Czyczerska

“…Moreover, it is necessary to quit smoking, increase physical activity, and reduce cholesterol, elevating products from diet such as saturated fats and alcohol. …”
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Molecular determinants of Neu5Ac binding to a tripartite ATP independent periplasmic (TRAP) transporter by Parveen Goyal, KanagaVijayan Dhanabalan, Mariafrancesca Scalise, Rosmarie Friemann, Cesare Indiveri, Renwick CJ Dobson, Kutti R Vinothkumar, Subramanian Ramaswamy

“…The Neu5Ac-bound structure reveals the interactions of Neu5Ac with the transporter and its relationship with the Na+ binding sites. Two of the Na+-binding sites are similar to those described previously. …”
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Non-contact tracking of shoulder bones using ultrasound and stereophotogrammetry by Ahmed Sewify, Ahmed Sewify, Maxence Lavaill, Maxence Lavaill, Dermot O’Rourke, Dermot O’Rourke, Maria Antico, Maria Antico, Peter Pivonka, Peter Pivonka, Davide Fontanarosa, Davide Fontanarosa, Saulo Martelli, Saulo Martelli

“…PurposeWe explored the integration of 3D ultrasound (US) imaging with motion capture technology for non-invasively tracking bones of the shoulder district during normal activity. Our study aimed to demonstrate ex-vivo the proposed 3D US method’s feasibility and accuracy of tracking shoulder bones in a controlled cadaveric shoulder positioned in various arm elevations (low, mid and high).MethodWe registered previously acquired full bone shapes to spatially small bony surface patches segmented from 3D US. …”
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A lipidated peptide derived from the C-terminal tail of the vasopressin 2 receptor shows promise as a new β-arrestin inhibitor by Rebecca L. Brouillette, Christine E. Mona, Michael Desgagné, Malihe Hassanzedeh, Émile Breault, Frédérique Lussier, Karine Belleville, Jean-Michel Longpré, Michel Grandbois, Pierre-Luc Boudreault, Élie Besserer-Offroy, Philippe Sarret

“…Molecular modelling studies also revealed that ARIP binds β-arrestins as does V2Rpp, the phosphorylated peptide derived from V2R, and that replacing the p-Ser and p-Thr residues of V2Rpp with Glu residues does not alter ARIP’s inhibitory activity on β-arrestin recruitment. Importantly, ARIP exerted an opioid-sparing effect in vivo, as intrathecal injection of ARIP potentiated morphine’s analgesic effect in the tail-flick test, consistent with previous findings of genetic inhibition of β-arrestins. …”
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Long-term results of antiviral therapy in patients with chronic hepatitis C with sustained virologic response by T. M. Ignatova, T. N. Lopatkina, V. P. Chulanov, Ye. V. Gaydasheva, S. N. Batskikh, G. V. Mikhaylovskaya, D. T. Abdurakhmanov, S. Yu. Karpov, Ye. N. Nikulkina, O. A. Chernova

“…Application of ultraresponsive PCR method allowed to reveal relapse half a year prior to its clinical and laboratory manifestation in 2 cases. …”
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Profile of Lumbar Spinal Stenosis Patients at Dr. M. Djamil Central Public Hospital from 2018-2022 by Inasa Faiza Akbar, Roni Eka Sahputra, Eka Fithra Elfi, Rizki Rahmadian, Dina Arfiani Rusjdi, Nelmi Silvia

“…Many LSS patients were housewives (42.62%) and reported light work activity (63.1%). The most common cause of LSS was degenerative factors (59%). …”
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JWST, ALMA, and Keck Spectroscopic Constraints on the UV Luminosity Functions at z ∼ 7–14: Clumpiness and Compactness of the Brightest Galaxies in the Early Universe by Yuichi Harikane, Akio K. Inoue, Richard S. Ellis, Masami Ouchi, Yurina Nakazato, Naoki Yoshida, Yoshiaki Ono, Fengwu Sun, Riku A. Sato, Giovanni Ferrami, Seiji Fujimoto, Nobunari Kashikawa, Derek J. McLeod, Pablo G. Pérez-González, Marcin Sawicki, Yuma Sugahara, Yi Xu, Satoshi Yamanaka, Adam C. Carnall, Fergus Cullen, James S. Dunlop, Eiichi Egami, Norman Grogin, Yuki Isobe, Anton M. Koekemoer, Nicolas Laporte, Chien-Hsiu Lee, Dan Magee, Hiroshi Matsuo, Yoshiki Matsuoka, Ken Mawatari, Kimihiko Nakajima, Minami Nakane, Yoichi Tamura, Hiroya Umeda, Hiroto Yanagisawa

“…We find that ∼70% of the bright galaxies at z ∼ 7 exhibit clumpy morphologies with multiple subcomponents, suggesting merger-induced starburst activity, which is consistent with SED fitting results showing bursty star formation histories. …”
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Internal Dosimetry in Patients Undergoing Peptide Receptor Radionuclide Therapy (PRRT) with 177Lu-[DOTA0-Tyr3] Octerotate: A Single-Center Experience by Elahe Mahmoudi, Mahasti Amoui, Mohammad Reza Deevband, Elahe Pirayesh, Mohammad Reza Asgari, Mehdi Ghorbani

“…The patients had a mean age of 53.5 ± 12 years (ranging from 36 to 70 years) and imaging data were collected at roughly 0 to 2 hours, 4 to 6 hours, 18 to 24 hours, and 36 to 48 hours after the injection of 6401± 628.4 MBq (range of 5500 MBq-7400 MBq) of 177Lu-[DOTA0-Tyr3] octerotate. Models of time-activity were established for different organs. Finally, using absorbed dose formulation and IDIAC-Dosage software, the mean absorbed dose in the organs was determined. …”
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Staphylococcus aureus susceptibilities from wounds of patients who use illicit fentanyl by Drew T. Dickinson, Stephen Saw, Lauren Dutcher, Christina Maguire, Adrienne Terico, Margaret Lowenstein, Sonal Patel

“…PWUF would benefit from joint management by infectious diseases and addiction medicine experts to ensure prescription of active therapy. Additional study is needed of PWUF in other regions. …”
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Saponin content in medicinal plants in response to application of organic and inorganic fertilizers: a meta-analysis by Junyan Lv, Junyan Lv, Shouzan Liu, Shouzan Liu, Chunli Hu, Lan Ding, Hongzhen Wang, Hongzhen Wang, Xin Li, Feng Yang, Feng Yang, Qiong Shen, Qiong Shen, Hongbin Zhang, Hongbin Zhang, Guobiao Ma, Guobiao Ma, Shaobo Zhang, Yan Bai, Yan Bai

“…However, systematic investigations on the influence of various fertilizers on the concentration of active compounds in saponin-containing medicinal plants remain insufficient. …”
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Effect of the adhesive added of copper applied with electric current on the ceramic/resin cement bond by Gabriel Augusto Silveira Sousa, Marcos Henrique Ramos da Silva, Lourenço Correr-Sobrinho, Rafael Pino Vitti, Evandro Piva, Rafael Leonardo Xediek Consani

“…IPS e.max Press ceramic discs included in rigid polyvinyl chloride tubes with chemically activated acrylic resin were divided into four groups (n = 10): RX + UA (silane + universal adhesive); RX + UA + EC (silane + universal adhesive + electrical current); RX + EA (silane + experimental adhesive); and RX + EA + EC (silane + experimental adhesive + electrical current). …”
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Heterochrony in orthodenticle expression is associated with ommatidial size variation between Drosophila species by Montserrat Torres-Oliva, Elisa Buchberger, Alexandra D. Buffry, Maike Kittelmann, Genoveva Guerrero, Lauren Sumner-Rooney, Pedro Gaspar, Georg C. Bullinger, Javier Figueras Jimenez, Fernando Casares, Saad Arif, Nico Posnien, Maria D. S. Nunes, Alistair P. McGregor, Isabel Almudi

“…We discovered that the activity of an otd eye enhancer is consistent with the difference in the expression of this gene between species, with the D. mauritiana enhancer sequence driving earlier expression than that of D. simulans. …”
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