An in-vivo herb-drug interaction study of IME-9 and glimepiride in nicotinamide-STZ-induced diabetic rats by Archana K. Thikekar, Asha B. Thomas, Sohan S. Chitlange

“…It is worth noting that herbs comprise different amounts of active phytochemicals that can affect enzymatic systems, transporters and physiological processes. …”
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Shear bond strength of three different fixed retainers: Stainless steel wires versus fiber reinforced composite (An in Vitro study) by Anees Mahmood Mudhir

“… Background and Objectives: Long term preservation of lingual retainer after active orthodontic treatment is mandatory in oral cavity to prevent teeth relapse to its original place before treatment which is documented in orthodontics and considered as a success factor of lingual bonded retainers. …”
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Direct and Indirect Methods for Studying Human Gut Microbiota by V. T. Ivashkin, O. S. Medvedev, E. A. Poluektova, A. V. Kudryavtseva, I. R. Bakhtogarimov, A. E. Karchevskaya

“…Trimethylamine N-oxide (TMAO) levels in the blood plasma and urine can also reflect the presence of specific bacterial clusters containing genes Cut, CntA/CntB and YeaW/YeaX. Therefore, further studies are required to reveal possible correlations between certain disorders and such parameters as the composition of gut microbiota, dietary patterns and TMAO concentration. …”
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Field Tests of Indoor Air Cleaners for Removal of PM2.5 and PM10 in Elementary School Classrooms in Seoul, Korea by Bangwoo Han, Keejung Hong, Dongho Shin, Hak-Joon Kim, Yong-Jin Kim, Sang Bok Kim, Sangwoo Kim, Cheong-Ha Hwang, Kwang-Chul Noh

“…The PM2.5 level in classrooms was effectively reduced by one or two air cleaners because PM2.5 infiltrated mainly from outdoors; meanwhile, PM10 could not be reduced as PM10 originated mainly from indoors from student activities. Air cleaners were more effective at removing PM2.5 and PM10 in classrooms with high airtightness than in classrooms with low airtightness. …”
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THE EFFECTIVENESS OF ZINC AND RISEDRONATE ON BONE TURNOVER IN RAT MODEL OF OSTEOPOROSIS ASSESSED WITH THE EXPRESSION OF β-CROSSLAPS by Adam Fajar, Mohammad Rizal Chaidir, Dicky Mulyadi, Ahmad Ramdan, Yoyos Dias Ismiarto

“…Previous research in rat model osteoporosis, Zinc have a potential effect to prevent and rebuild bone structure with osteoblast stimulation in bone formation and osteoclast activity inhibition in bone resorption by increasing Osteoprotegerin production, that inhibit bond between RANKL and RANK. …”
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Establishing Normal Variances and Expectations for Quadriceps Limb Symmetry Index Benchmarks Based on Time from Surgery After Anterior Cruciate Ligament Reconstruction. by Sean Hazzard, Saoirse Connolly, Ashley Wiater, Isabella Sprague, Emily Doolan-Roy, Rachel Lampros, Peter D Asnis

“…Male sex is associated with decreased amount of time to obtain clearance for running and for full activity. Male sex is associated with decreased amount of time to regain quadriceps symmetry however this was not significant…”
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A model-based spectral directional approach reveals the long-term impact of COVID-19 on cardiorespiratory control and baroreflex by Beatrice Cairo, Francesca Gelpi, Vlasta Bari, Martina Anguissola, Pavandeep Singh, Beatrice De Maria, Marco Ranucci, Alberto Porta

Subjects: “…SARS-CoV-2…”
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Three Years of High Time-resolution Air Pollution Monitoring in the Complex Multi-source Harbor of New York and New Jersey by Gayle Hagler, Dan Birkett, Ronald C. Henry, Richard E. Peltier

“…To better understand air quality during increasing emission controls at the Port of New York and New Jersey (“Port”), an air monitoring station was sited to minimize collinearity of sources along ordinal directions. …”
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Interventions that prevent or reduce perinatal loneliness and its proximal determinants: a restricted scoping review by Ruth Naughton-Doe, Rebecca Nowland, Stephanie Tierney, Martin Webber, Anja Wittkowski

“…We included studies that described and/or evaluated interventions in published studies that intentionally or unintentionally reduced loneliness, or its proximate determinants, such as social connectedness and social support. …”
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Unveiling molecular insights: in silico exploration of TLR4 antagonist for management of dry eye syndrome by Kothandan Sudhakar, Neeru Dugar, Srikanth Jupudi, Ravichandran Ashwin, Kuppusamy Gowthamarajan

“…Celastrol, lumacaftor and nilotinib were selected for further molecular dynamics studies for a deeper understanding of molecular systems consisting of protein and ligands by using the Desmond module of the Schrodinger Suite.Results The docking results revealed that the compounds are having binding affinity in the range of −5.1 to −8.78 based on the binding affinity and three-dimensional interactions celastrol, lumacaftor and nilotinib were further studied for their activity by molecular dynamics. Among the three compounds, celastrol was the most stable based on molecular dynamics trajectory analysis from 100 ns in the catalytic pockets of 2Z63.pdb.pdb. …”
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3-Acetyldeoxynivalenol induces pyroptosis in leydig cells via METTL3-mediated N6-methyladenosine modification of NLRP3 by Yangyun Wang, Chaoliang Shi, Wei Jiao, Xiaoxiang Wan

“…Mechanistic investigations further revealed that 3-ADON exposure triggers pyroptosis in TM3 cells, as evidenced by upregulation of NLRP3, activation of caspase-1, ASC, and GSDMD. Moreover, 3-ADON treatment resulted in a significant upregulation of METTL3 expression and increased global mRNA m6A modification levels. m6A sequencing and functional assays established that METTL3-mediated m6A modification of NLRP3 mRNA enhances its stability and expression. …”
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The impact of the ursodeoxycholic acid as monotherapy and in the combination with the lactulose on the biochemical blood tests values of the nonalcoholic steatohepatitis patients by I. V. Mayev, Yu. A. Kucheryavyy, S. V. Morozov, M. G. Saidullayeva, M. L. Akhtayeva, N. Yu. Stukova, E. A. Krasnyakova

“…The credible dynamic of the biochemical tests values of the cytolysis as compared with the baseline (the reducing of the activity of the alanine transaminase and the aspartate transaminase) and of the cholestasis (gamma-glutamyl transpeptidase) was observed; the positive changes in the lipid profile (the increase in the concentration of the high density lipoproteins and the reduction in the total cholesterol, the low density lipoproteins, the very low density lipoproteins and triglycerides ) were seen during the treatmet in both groups. …”
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TNBC response to paclitaxel phenocopies interferon response which reveals cell cycle-associated resistance mechanisms by Nicholas L. Calistri, Tiera A. Liby, Zhi Hu, Hongmei Zhang, Mark A. Dane, Sean M. Gross, Laura M. Heiser

“…Transcription factor (TF) enrichment analysis identified 13 TFs that were both enriched based on activity of downstream targets and also significantly upregulated after paclitaxel treatment. …”
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Selection and Success in Badminton: The Role of Lobs and Smashes in Junior Athletes' Performance by Touptiolo Touptiolo, Helmina Ria Siregar, Vina Mardatila Tarigan, Yogi Suwananda, Soukaina Hattabi, Willette Nance

“…These findings provide insights into optimal shot selection and its impact on game outcomes among junior badminton players. …”
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The impact of mobile health interventions on service users' health outcomes and the role of health professions: a systematic review of systematic reviews by Fathiya Alkhuzaimi, Deborah Rainey, Christine Brown Wilson, Jacqueline Bloomfield

“…Behavioural improvements were also reported, including better medication adherence and physical activity. Psychological benefits, such as reduced anxiety and enhanced patient satisfaction, were noted. …”
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Estimating the Health-Related Quality of Life Benefit of Prophylactic Treatment for COVID-19 in Immunocompromised People: A Multimethod Valuation Study by Katy Gallop, Rebekah Hall, Michael Watt, Daniel Squirrell, Neil Branscombe, Sofie Arnetop, Andrew Lloyd

“…PrEP would potentially result in a utility gain between 0.082 and 0.326, dependent on valuation approach and expected change in behavioral restrictions, leading to improvements in daily activities and emotional well-being.…”
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On Job Training and Employee Productivity in Banking Institutions in Uganda: A Case Study of Centenary Bank Kabale Branch. by Nakero, Sarah

“…Centenary bank should take its time to talk to the employees, and explain how their role affects the banks operations, so that they see the big picture. …”
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The Suitability of Recycled Domestic Wastewater in Plain Concrete Production. by Orishaba, James

“…Concrete production is one of the activities that use a lot of water in its mix but fresh potable water is greatly reducing due to highly increasing population and industries in the world. …”
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The Role of Non-Governmental Organisations (NGOs) on the Socio¬economic Transformation of Rural Areas in Nyarusiza Sub-County Kisoro District. by Izabayo, Joan

“…There are several successful non-governmental organizations (NGOs) that have actively participated in the development of society by creating employment opportunities and livelihoods for the poor section of society through non-governmental organizations (NGO's) and the socio-economic transformation of rural areas in Nyarusiza Sub-county Kisoro district.…”
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Assessing the Role of MBIFCT as a Non-Governmental Organisations (NGO) in Socio-Economic Transformation of Rural Areas in Gitenderi Parish Nyarusiza Sub-County Kisoro District. by Kwebiha, Alex

“…There are a number of successful NGOs who have actively participated for the development of the society by creating employment opportunities and livelihood for the poor section of the society on the Non-governmental Organizations (NGO's) and the socio-economic transformation of rural areas in Nyarusiza Sub¬county Kisoro district.…”
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