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9761
Divergent thinking in groups during cold-water immersion is impaired by cold stress not the cold shock response
Published 2025-02-01“…To date, research shows that executive functioning is generally impaired by intense, acute stress, which implies the ability to think through potential actions to maximize survival would also be impaired by the cold shock response.MethodsTo examine whether the severity of cold shock response impairs higher-level thinking in a group, 29 active duty service members completed a group format Divergent Association Task (DAT; 4–5 per group) prior to and during a 13-min cold-water immersion (water temperature: 1.3°C, air temperature: −2.7°C).ResultsResults showed no relationship between cold shock response magnitude, indexed by peak heart rate, and DAT performance. …”
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9762
Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats
Published 2025-02-01“…Overall, our data provides novel insights into the molecular basis by which JNK inhibition exerts its metabolic effect in the metabolically active tissues. …”
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9763
Evaluation of chicken liver meal as fish meal alternative in large yellow croaker Larimichthys crocea diet: Effects of growth performance, antioxidant capacity, intestinal health a...
Published 2025-03-01“…The CLM75 and CLM100 diets led to a significant decrease in the activity of amylase (AMS), lipase (LPS), catalase (CAT) as well as total antioxidant capacity (T-AOC) for liver of Larimichthys crocea, while remarkably increasing malondialdehyde (MDA) content. 16S rRNA sequencing revealed that CLM75 and CLM100 diets resulted in increased relative abundances of Proteobacteria phylum and decreased relative abundances of Firmicutes phylum. …”
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9764
The pro-inflammatory cytokine Tumor Necrosis Factor alpha (TNF-α) in Diabetic Nephropathy
Published 2024-07-01“…There is now proof that inflammation and activated innate immunity play important roles in the etiology of problems with diabetes. …”
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9765
The effect of blue-blocking intraocular lenses on circadian biological rhythm: protocol for a randomised controlled trial (CLOCK-IOL colour study)
Published 2015-05-01“…Secondary outcomes are fasting plasma glucose, triglycerides, cholesterol, glycated haemoglobin, sleep quality, daytime sleepiness depressive symptoms, light sensitivity, the circadian rhythm of physical activity, wrist skin temperature and urinary melatonin metabolite. …”
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9766
Dose-dependent effects of hydroquinone on liver injury and lipid dysregulation based on SCD1/AMPK signaling pathway in C57BL/6 mice
Published 2025-01-01“…Hydroquinone (HQ) is extensively utilized in various industrial applications and as a dermatological agent; however, its metabolic processes and toxicological effects, particularly in the liver, remain insufficiently understood. …”
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9767
Progress Analysis and Development Prospects of Soil Ecological and Environmental Effects of Interlayer Construction
Published 2024-12-01“…[Methods] The effects and regulation mechanisms of interlayer construction on soil physical structure, soil water-salt-heat, soil nutrient status, soil enzyme activities, soil microbial properties, and crop productivity were comprehensively addressed. …”
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9768
Population genetics of Glossina palpalis gambiensis in the sleeping sickness focus of Boffa (Guinea) before and after eight years of vector control: no effect of control despite a...
Published 2024-02-01“…Human African trypanosomosis (HAT), also known as sleeping sickness, is still a major concern in endemic countries. Its cyclical vector are biting insects of the genus Glossina or tsetse flies. …”
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9769
Estimating population attributable risk fraction of determinants of pediatric obesity
Published 2025-02-01“…In addition to physical examination, a self-administered questionnaire was completed to obtain the study variables including dietary behavior, physical activity, screen time, sleep duration, socioe-conomic status (SES), and passive smoking. …”
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9770
Lactoferrin: a secret weapon in the war against pathogenic bacteria
Published 2024-10-01“…Moreover, cleavage of the Lf molecule could promote the production of lactoferricins (Lfcins) and lactoferrampin (Lfampin) from the N-terminal end, which are known to often have stronger antimicrobial effects than the native molecule, as well as analogous peptides, such as HLopt2, which have also shown enhanced antimicrobial activity. Bovine Lf (bLf) has been approved by the US Food and Drug Administration (FDA), and the European Food Safety Authority for its use as a dietary supplement in food products. …”
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9771
Sodium alginate ameliorates health in freshwater fish through gut-liver axis modulation under high carbohydrate diets
Published 2025-03-01“…Our transcriptomic analysis on liver tissue showed that detoxification-related differentially expressed genes (DEGs) were less active in HC group than in NC group. In contrast, DEGs linked to fatty acid synthesis increased in LA group versus HC group. …”
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9772
“Common sense is hard work” but benefits from persistent collaboration: Lessons learnt from the development of The Collaborative Network for European Clinical Trials for Children (...
Published 2025-04-01“…Results: 12 trials were supported by sites coordinated at national level and integrated at European level. …”
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9773
The Feasibility and Acceptability of a Community Science Approach to Explore Infant Formula Preparation Safety in the Home
Published 2025-01-01“…Parents often seek out information about health and parenting topics, but despite this, there have been few attempts to actively engage them in the research process. We aimed to assess the feasibility and acceptability of using community science (CS) in a pilot study to explore infant formula preparation safety in the home in the United Kingdom. …”
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9774
Air pollution exposures in early life and brain development in children (ABC): protocol for a pregnancy cohort study
Published 2025-02-01“…At entry, mothers (n=400) are administered surveys to characterise air pollution exposures reflecting household features and occupational activities and provide blood (for lead analysis) and urine specimens (for polycyclic aromatic hydrocarbon (PAH) metabolites). …”
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9775
Observations of Loki Patera by Juno during Close Flybys
Published 2025-01-01“…Loki shows a thermal structure unlike other active lava lakes previously reported, with some brightening near the lake’s perimeter but lacking the continuous “hot ring” seen at other paterae. …”
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9776
Heavy metal and metalloid pollution: A systematic review of health implications for pregnant women, children, and geriatrics in the East African region
Published 2025-04-01“…Despite increasing industrialisation and mining activities in the region, there is a lack of comprehensive analysis addressing the exposure pathways and associated health implications of these toxicants. …”
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9777
Spatial-temporal evolution of habitat quality in tropical monsoon climate region based on “pattern–process–quality” – a case study of Cambodia
Published 2025-02-01“…The results show that (1) during 2000–2022, forest in Cambodia covered a wide range, showing a landscape pattern mainly distributed in the east and west. (2) The degree of fragmentation of impervious landscape pattern increased gradually from 2000 to 2022, indicating that it was seriously affected by human activities and natural factors, and with the increase in elevation and slope, the area of various types converted to impervious decreased. (3) During 2000–2022, high habitat quality areas were concentrated in Tonle SAP Lake in the east, southwest, and central part of Cambodia, while low habitat quality areas were concentrated in the central part. (4) Natural factors, socio-economic factors, policies, and regulations all have an impact on the change in land use pattern and habitat quality in Cambodia.…”
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9778
Microplastic exposure induces HSP90α secretion and aggravates asthmatic airway remodeling via PI3K-Akt-mTOR pathway
Published 2025-02-01“…Then, microplastics were proved to activate PI3K-Akt-mTOR pathway by prompting airway epithelial cells secrete HSP90α and proliferation of airway smooth muscle cells(ASMCs), leading to airway narrowing and hypersensitivity. 1G6-D7 is a monoclonal antibody to HSP90, which can reverse the pulmonary inflammation infiltration, mucus production, and airway hyperresponsiveness(AHR). …”
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9779
A study on the differences in the gut microbiota and metabolism between male and female mice in different stress periods
Published 2025-02-01“…The results showed that female mice were highly active and prone to anxious behavior before stress, and the levels of f-Rikenellaceae, f-Ruminococcaceae and 16α-hydroxyestrone were significantly different from those in male mice. …”
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9780
Redox-mediated reverse water gas shift integrated with ammonia cracking over Ni/La0.75Sr0.25Cr0.5Mn0.5O3−δ
Published 2025-05-01“…The mixture of LSCM and Ni catalyst at a weight ratio of 10:1 increases the NH3 cracking activity fivefold compared to using only LSCM. Because the reduction of LSCM proceeds through a two-step mechanism that requires the prior cracking of NH3, it also substantially increases the redox reactivity of LSCM. …”
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