Forsythia suspensa leaf fermented tea extracts attenuated oxidative stress in mice via the Ref-1/HIF-1α signal pathway and modulation of gut microbiota by Lijuan Li, Yating zhao, Yuxin Ding, Lanze Guo, Ruiyao Dai, Aixiang Chen, Guofeng Duan

“…Abstract Forsythia suspensa leaf fermented tea (FSLFT) is made from tender buds of Forsythia suspensa collected in spring. The main active components of FSLFT include forsythiaside, forsythia ester glycoside, rutin, and forsythia flavonoids, which have antibacterial, antioxidant, liver-protective, and immune-regulatory effects. …”
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How spinal GABAergic circuits modulate cerebral processing of postsurgical pain by Bruno Pradier, Daniel Segelcke, Nathalie Just, Mirjam Augustin, Nina Nagelmann, Cornelius Faber, Esther Pogatzki-Zahn

“…While fMRI studies show consistent brain activity changes during mechanical stimulation in post-surgical pain, central processing of pain at rest and the role of spinal GABAergic circuits on surgical pain processing is currently unclear. …”
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Liquefaction potential analysis using the Tsuchida method and correlation of Relative Density (Dr) − D50 at Padang Beach by Andriani, Afifa Mifta, Yoriadi Didi, Shubhi Nurul Hadie Muhammad, Ahmad Fauziah

“…Indonesia’s seismic activity necessitates careful consideration of earthquake risks in construction projects, as seen in the 2009 Padang’s Earthquake with high sand content and water table near the coast. …”
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River water quality monitoring using machine learning with multiple possible in-situ scenarios by Dani Irwan, Saerahany Legori Ibrahim, Sarmad Dashti Latif, Chris Aaron Winston, Ali Najah Ahmed, Mohsen Sherif, Amr H. El-Shafie, Ahmed El-Shafie

“…Future studies should concentrate on resolving these issues and investigating other elements, such as environmental variables, land use patterns, and human activity, that may affect the forecast of water quality.…”
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Regulatory mechanism of exogenous myo-inositol improving high temperature stress tolerance of tomato seedlings by CHEN Yan, HAN Liyuan, DU Zilong, ZHU Dongxing, ZHU Weimin, ZHANG Yingying

“…Exogenous myo-inositol increased proline and soluble sugar contents and peroxidase activity, and decreased malondialdehyde, hydrogen peroxide, and superoxide anion contents in tomato seedlings at high temperature. …”
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Simulation of Software Development Team Productivity Incorporating Social and Human Factors: A System Dynamics Model by Luz Marcela Restrepo-Tamayo, Gloria Piedad Gasca-Hurtado, Johnny Valencia-Calvo

“…Managing software development work teams requires planning resources and activities to complete projects and deliver products satisfactorily and successfully. …”
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Intermediate pyrolysis of Ficus nitida wood in a fixed-bed reactor: effect of pyrolysis parameters on bio-oil and bio-char yields and properties by Tabal, Amine, Belyazid, Oumayma, Dahman, Hicham, Berrich, Emna, Jeguirim, Mejdi, El Achaby, Mounir, El Harfi, Khalifa, Aboulkas, Adil

“…Thus, it can be used as promising material in various application such as activated carbon synthesis and biofertilizers.…”
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Role of Inflammation and Motility Disorders in the Development, Course and Consequences of Functional Gastrointestinal and Biliary Tract Diseases (Literature Review and Expert Pane... by V. T. Ivashkin, D. S. Bordin, T. L. Lapina, M. A. Livzan, A. V. Okhlobystin, E. A. Poluektova, A. S. Trukhmanov, Yu. P. Uspenskiy, Yu. O. Shulpekova

“…Low-grade inflammation can be considered as a morphological substrate of functional diseases with an increase in activated mastocytes and eosinophils, T-helpers 2 and T-helpers 17 in the gastrointestinal mucosa. …”
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Clinical and molecular response to alpha1‐oleate treatment in patients with bladder cancer by Farhan Haq, Samudra Sabari, Jaromir Háček, Antonín Brisuda, Ines Ambite, Michele Cavalera, Parisa Esmaeili, Murphy Lam Yim Wan, Shahram Ahmadi, Marek Babjuk, Catharina Svanborg

“…RNA sequencing of tissue biopsies confirmed the activation of apoptotic cell death and strong inhibition of cancer gene networks, including bladder cancer related genes. …”
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Oral Health Status and Anxiety Level Amongst the Borderline Security Force Personnel and Their Family Members by Deepali Agarwal, Bharathi Purohit, Upendra Singh Bhadauria, Sneha Malhotra, Manali Deb Barma, Harsh Priya

“…The primary role of border security personnel is to safeguard borders against illegal trans-border activities during peacetime and provide military support during wartime. …”
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Biodiversity futures: digital approaches to knowledge and conservation of biological diversity by H. Freitas, H. Freitas, A. C. Gouveia, A. C. Gouveia

“…However, the scale of human activities has significantly impacted the planet's biodiversity, with many species facing extinction in the coming decades with unknown consequences. …”
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MyVivarium: A cloud-based lab animal colony management application with realtime ambient sensing by Robinson Vidva, Mir Abbas Raza, Jaswant Prabhakaran, Ayesha Sheikh, Alaina Sharp, Hayden Ott, Amelia Moore, Christopher Fleisher, Hailey Netherton, Evan Goldstein, Pothitos M. Pitychoutis, Tam V. Nguyen, Aaron Sathyanesan

“…Finally, we designed a low-cost system to sense ambient humidity, temperature, vivarium worker activity, and room illuminance. These data are then sent to MyVivarium in realtime providing information relevant to colony well-being. …”
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Targeting natural antioxidant polyphenols to protect neuroinflammation and neurodegenerative diseases: a comprehensive review by Maroua Jalouli, Md Ataur Rahman, Partha Biswas, Hasanur Rahman, Abdel Halim Harrath, In-Seon Lee, In-Seon Lee, Sojin Kang, Jinwon Choi, Moon Nyeo Park, Bonglee Kim, Bonglee Kim

“…Polyphenols have been extensively studied for their ability to regulate inflammatory responses by modulating the activity of pro-inflammatory genes and influencing signal transduction pathways, thereby reducing neuroinflammation and neuronal death. …”
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Exploring the decline in health index of the Qarhan salt lake region in Qinghai Province, China: A 40-year assessment by Pengfei Ji, Qian Shen, Ru Wang, Yue Yao, Bing Zhang, Wenting Xu, Yuting Zhang, Wenqi Kou, Wenxin Li

“…In this study, we develop a Salt Lake Health Index (SLHI), suitable for assessing salt lake regions affected by human activities, using the Analytic Hierarchy Process and remote sensing technology. …”
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Biogenic silver nanoparticles produced by Trichoderma reesei inhibit SARS-CoV-2 infection, reduce lung viral load and ameliorate acute pulmonary inflammation by Marcus V.M.V. Amaral, Cláudia B. Carraro, Amanda C.C. Antoniêto, Mariana N. Costa, Thais F.C. Fraga-Silva, Ualter G. Cipriano, Rodrigo P.F. Abuná, Tamara S. Rodrigues, Ronaldo B. Martins, Andreia M. Luzenti, Glaucia R. Caruso, Priscyla D. Marcato, Vania L.D. Bonato, Dario S. Zamboni, Bergman M. Ribeiro, Sônia N. Báo, Joao S. da Silva, Flávio P. Veras, Roberto N. Silva

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Coupling of an Au@AgPt nanozyme array with an micrococcal nuclease-specific responsiveness strategy for colorimetric/SERS sensing of Staphylococcus aureus in patients with sepsis by Xueqin Huang, Yingqi Yang, Hanlin Zhou, Liping Hu, Annan Yang, Hua Jin, Biying Zheng, Jiang Pi, Jun Xu, Pinghua Sun, Huai-Hong Cai, Xujing Liang, Bin Pan, Junxia Zheng, Haibo Zhou

“…In the presence of S. aureus, the secreted MNase preferentially cut the nucleobase AT-rich regions of DNA sequences on magnetic beads (MBs) to release alkaline phosphatase (ALP), which subsequently mediated the oxTMB reduction for inducing the colorimetric/SERS signal fade away. …”
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Metabolomics and transcriptomics analyses revealed overexpression of TaMGD enhances wheat plant heat stress resistance through multiple responses by Dongyun Ma, Haizhou Hu, Jianchao Feng, Beiming Xu, Chenyang Du, Yang Yang, Yingxin Xie, Chenyang Wang

“…Under high-temperature stress, the overexpressed wheat lines exhibited higher grain weight, increased antioxidant enzyme activity, and lower H2O2 and malondialdehyde contents in leaves. …”
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Comprehensive genome-wide analysis of ARF transcription factors in orchardgrass (Dactylis glomerata): the positive regulatory role of DgARF7 in drought resistance by Miaoli Wang, Wen Liu, Guangyan Feng, Gang Nie, Zhongfu Yang, Feixiang Hao, Linkai Huang, Xinquan Zhang

“…Overexpressed Arabidopsis lines of DgARF7 exhibited a markedly higher relative water content and superoxide dismutase activity, while the malondialdehyde content was significantly decreased compared to wild type under drought stress. …”
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Novel (Q)SAR models for prediction of reversible and time-dependent inhibition of cytochrome P450 enzymes by Sadegh Faramarzi, Arianna Bassan, Kevin P. Cross, Xinning Yang, Glenn J. Myatt, Donna A. Volpe, Lidiya Stavitskaya

“…Furthermore, five quantitative structure-activity relationship (QSAR) models were developed to predict not only time-dependent inhibition of CYP3A4, an enzyme that metabolizes approximately 50% of all marketed drugs, but also reversible inhibition of 3A4, 2C9, 2C19 and 2D6. …”
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Bicyclic peptide-enhanced covalent inhibitor of SARS-CoV-2 3CL protease by Qian Wang, Yanhui Wang, Jian Li, Hong Liu, Shiyu Chen

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