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  1. 8181

    Activation of PPARγ Protects Obese Mice from Acute Lung Injury by Inhibiting Endoplasmic Reticulum Stress and Promoting Mitochondrial Biogenesis by Yin Tang, Ke Wei, Ling Liu, Jingyue Ma, Siqi Wu, Wenjing Tang

    Published 2022-01-01
    “…GW9662 bound to PPARγ and blocked its transcriptional activity and then diminished the protective effect of PPARγ on lung tissues. …”
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  3. 8183

    Mitofusin2 Promotes β Cell Maturation from Mouse Embryonic Stem Cells via Sirt3/Idh2 Activation by Li Lu, Li Zhitao, Cui Nannan, Huang Mingzhu, Hu Xiaoping, Hong Dongsheng, Pan Zongfu, Lu Xiaoyang

    Published 2022-01-01
    “…In immature and mature β cells, Mfn2 and its correlated genes were enriched in tricarboxylic acid (TCA) cycle-related pathways. …”
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  4. 8184

    MAPK4 inhibits the early aberrant activation of B cells in rheumatoid arthritis by promoting the IRF4-SHIP1 signaling pathway by Pei Huang, Guangli Yang, Pingping Zhang, Yin Zhu, Yaning Guan, Jian Sun, Qian Li, Yang An, Xiaoqi Shi, Juanjuan Zhao, Chaohong Liu, Zhixu He, Yan Chen, Zuochen Du

    Published 2025-01-01
    “…In this study, we identified a significant reduction in MAPK4 expression in both RA patients and collagen-induced arthritis (CIA) mouse models, which correlates with disrupted B cell activation. …”
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  5. 8185

    Activities in the Context of a Network, Trust and Internal Resources as Antecedents of the Effectiveness of Network Governance: a Study of the Impact on the Performance of the Companies Involved by Henrique Cordeiro Martins, Lucas Araújo Bassalo de Siqueira, José Antônio Sousa Neto

    Published 2019-01-01
    “…With few theories that approach the subject, this work has as its main objective the investigation of the background of network performance, trust and internal resources in the effectiveness of the NG, and its influence on the performance of the companies. …”
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  6. 8186

    Cortistatin-14 Exerts Neuroprotective Effect Against Microglial Activation, Blood-brain Barrier Disruption, and Cognitive Impairment in Sepsis-associated Encephalopathy by Qiang Wen, Qian Ding, Jinchao Wang, Yanhua Yin, Shangchen Xu, Yuanrong Ju, Hongsheng Ji, Bin Liu

    Published 2022-01-01
    “…The present study aimed to explore the neuroprotective role of cortistatin-14 in sepsis-associated encephalopathy and its underlying mechanisms in a mouse model. A septic mice model was established using the cecal ligation and puncture (CLP) method. …”
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  7. 8187

    Alteration in the Cytokine Secretion of Bone Marrow Stromal Cells from Patients with Chronic Myelomonocytic Leukemia Contribute to Impaired Hematopoietic Supportive Activity by Hui Shi, Yingshao Wang, Rong Li, Wen Xing, Feng-Chun Yang, Jie Bai, Yuan Zhou

    Published 2018-01-01
    “…To assess whether the altered cytokine secretion was one of the mechanisms to mediate the impaired hematopoietic supportive activity of CMML-BMSCs, a transwell coculture followed by cytokine array was performed. …”
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  8. 8188
  9. 8189

    CSF3 promotes colorectal cancer progression by activating p65/NF-κB signaling pathway and inducing an immunosuppressive microenvironment by Junfeng Xu, Na Li, Hui Xie, Changwei Duan, Xingchen Liao, Ruoran Li, Heng Zhang, Yuanming Pan, Xianzong Ma, Shuwen Du, Jianqiu Sheng, Xin Wang, Lang Yang, Peng Jin

    Published 2025-03-01
    “…In vivo, silencing CSF3 resulted in reduced tumor growth, weight, and volume, indicating its potential as a therapeutic target. Mechanistically, CSF3 was found to mediate CRC development by activating the NF-κB signaling pathway, as evidenced by the decreased phosphorylation of p65 and reduced IκBα ubiquitination in CSF3-silenced cells. …”
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  10. 8190

    Biological activity produced by ruthenium chloride on perfusion pressure, left ventricular pressure and heart failure using an isolated rat heart model by Figueroa-Valverde Lauro, Rosas-Nexticapa Marcela, Alvarez-Ramirez Magdalena, Lopez-Ramos Maria, Aguilar-Sanchez Emilio, Mateu-Armand Virginia

    Published 2024-07-01
    “…Aim and Objectives: The aim of this investigation was to evaluate the biological activity of ruthenium chloride on perfusion pressure, left ventricular pressure and heart failure. …”
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  14. 8194

    Timing of congenital cytomegalovirus diagnosis and missed opportunities by Mallory R. Baker, Xing Wang, Ann J. Melvin

    Published 2025-02-01
    Subjects: “…congenital cytomegalovirus (cCMV) infection…”
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