Immunogenic dying cells elicit potent anti-tumor T cell immunity against lung metastasis and tumorigenesis by Min Hu, Xinyu Meng, Tong Wang, Yifan Wang, Xiaodong Chen, Dongliang Xu, Wei He, Hongjia Zhang, Wenzheng Guo, Bo Jing, Siwei Zhang, Jianhua Xu, Beibei Sun, Xueqian Sun, Tingting Liu, Na Ni, Tongtong Zhang, Wenwen Cui, Xiaoyu Wu, Liping Xia, Feng Yao, Fang Zhang, Jing Du, Jiong Deng

“…Abstract Purpose Immune checkpoint blockades (ICBs) are promising, however they do not fit all types of tumor, such as those lack of tumor antigens. …”
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The adaptation of rainbow trout to warmer water: Oxidative damage in the germinal line by Vianel Sevastei, Sonia A. Crichigno, M. Victoria Santos, Andrea Trochine, Julio C. Painefilú, Noemí Zaritzky, Víctor E. Cussac

“…We examined: Oxidative damage (lipid peroxidation) and activities of antioxidant enzymes; Catalase (CAT), Glutathione S-Transferases (GST), and Superoxide Dismutase (SOD), in liver, testicle, and spermatozoa. …”
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USP4-mediated CENPF deubiquitylation regulated tumor metastasis in colorectal cancer by Zhongdong Xie, Hanbin Lin, Yuecheng Wu, Yanan Yu, Xintong Liu, Yating Zheng, Xiaojie Wang, Jiashu Wu, Meifang Xu, Yuting Han, Qiongying Zhang, Yu Deng, Lin Lin, Yan Linzhu, Li Qingyun, Xinjian Lin, Ying Huang, Pan Chi

“…In this study, we identified autophagy activation as a prognostic indicator in CRC and observed that the expression of key autophagy proteins is elevated in metastatic and recurrent cases. …”
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Prevalence, Dispersion and Nature of Bioaerosols over a Solid Landfill Site in Central India by Priyanka D. Bhoyar, Pooja Kamdi, Amit Bafana, Panuganti C. S. Devara, Saravanadevi Sivanesan, Amrit Kumar, Kannan Krishnamurthi

“…Abstract Bioaerosols (or biological aerosols) consist of aerosol particles that originate biologically either as fully active component or as whole or part of inactive fragments. …”
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Spatial-temporal Characteristics and Source Apportionment of Ambient VOCs in Southeast Mountain Area of China by Xiaoting Ji, Ke Xu, Dan Liao, Gaojie Chen, Taotao Liu, Youwei Hong, Sijun Dong, Sung-Deuk Choi, Jinsheng Chen

“…Based on the OH radical loss rate (LOH) and ozone formation potential (OFP) analysis, alkenes had the highest chemical activity, especially the contribution of isoprene in rural areas. …”
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Management of adult patients with alcoholic liver disease: clinical guidelines of the Russian Scientific Liver Society by V. T. Ivashkin, M. V. Mayevskaya, Ch. S. Pavlov, Yu. P. Sivolap, V. D. Lunkov, M. S. Zharkova, R. V. Maslennikov

“…Gamma-glutamyltranspeptidase activity and the level of carbohydrate-deficient transferrin are recommended to verify regular alcohol abuse in clinical practice. …”
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The Impact of Lockdown on eBC Mass Concentration over a Semi-arid Region in Southern India: Ground Observation and Model Simulations by Surya Nagi Reddy Palle, Chakradhar Rao Tandule, Raja Obul Reddy Kalluri, Balakrishnaiah Gugamsetty, Rama Gopal Kotalo, Lokeswara Reddy Thotli, Bhavyasree Akkiraju, Siva Sankara Reddy Lingala

“…The sharp decrease (~35%) of eBC mass concentration observed during the lockdown (LD) period as compared with before lockdown (BLD) period, was mainly due to the reduction of anthropogenic activities and meteorology. Furthermore, during the entire LD period, the net composite forcing at the top of the atmosphere (TOA) and at the surface (SUR) varied from −4.52 to −6.19 Wm −2 and −22.91 to −29.35 Wm −2, respectively, whereas the net forcing in the atmosphere (ATM) varied from 17.27 to 23.16 Wm−2. …”
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Effect of microstructure and neutron irradiation defects on deuterium retention in SiC by Alex Leide, Weicheng Zhong, Isabel Fernandez-Victorio, Isabel Fernandez-Victorio, Duc Nguyen-Manh, Duc Nguyen-Manh, Takaaki Koyanagi

“…Retention of hydrogen isotopes is a critical concern for operating fusion reactors as retained tritium both activates components and removes scarce fuel from the fuel cycle. …”
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Post-traumatic arthritis: overview on pathogenic mechanisms and role of inflammation by Roberta Ramonda, Leonardo Punzi, Anna Scanu, Francesca Oliviero, Roberto Luisetto, Paola Galozzi, Marta Favero

“…A variety of molecular, mechanobiological and cellular events involved in the pathogenesis and the progression of PTA have been identified. The activation of inflammatory mechanisms during the PTA acute phase appears to play a critical role in the chronic disease onset. …”
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Functional Outcome by Evaluation of DASH Score on Drop Hand Patient Treated with Jones’ Tendon Transfer: A Retrospective Study by Tito Sumarwoto, Seti Aji Hadinoto, Adhitya Indra Pradhana

“…The average score was 12.48, indicating that most patients could cope with most daily living activities postoperatively. Conclusions: Surgical intervention for drop hand due to radial nerve palsy using the Jones tendon transfer technique yielded a satisfactory functional outcome based on the DASH score.…”
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A systematic review of Aspilia africana (Pers.) C.D. adams traditional medicinal uses, phytoconstituents, bioactivities, and toxicities by Roggers Gang, Denis Okello, Yeongjun Ban, Youngmin Kang

“…The extracts and bioactive phytochemicals of A. africana have revealed several pharmacological properties, including antimalarial, anticancer, wound healing, anti-inflammatory, antidiabetic, and antimicrobial activities. However, the major components responsible for these bioactivities and their mechanisms of action in some diseases have not yet been clearly identified. …”
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In the coevolution of cotton and pathogenic fungi, resistant cotton varieties lead to an escalation in the virulence of Verticillium dahliae by Yalin Zhang, Lifang Cui, Ruibing Liu, Zili Feng, Hongjie Feng, Jinglong Zhou, Lihong Zhao, Feng Wei, Heqin Zhu

“…Pathogenicity assays demonstrated that the virulence of the offspring strains triggered by continuous induction of disease-resistant cotton cultivar increased from the 4th generation and reached its peak by the 6th generation. Additionally, the transcriptome analysis revealed that the 4th and 6th generations of strains differentially expressed genes (DEGs) accumulated a significant number of response genes associated with pathogen pathogenicity differentiation, including the mitogen-activated protein kinase (MAPK) signaling pathway, amino and antibiotic biosynthesis, phenylpropanoid metabolism. …”
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Microscale insight into the proton concentration during electrolytic reaction via an optical microfiber: potential for microcurrent monitoring by a dielectric probe by Yunyun Huang, Jiaxuan Liang, Haotian Wu, Pengwei Chen, Aoxiang Xiao, Bai-Ou Guan

“…Examples include photocurrent attenuation in photogenerated carrier materials during illumination, electrical activation in nerve cells, and fluctuations in the efficiency of electrical energy generation during battery discharge. …”
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A review of metabolic calorimetric applications in plant stress, waste management, and diagnostics by Michael Bayode, Ifeoluwaposi Ogundana, Oluwatosin Ogundare, Elizabeth Awodire, Patience Abbah, Israel Onifade, Adeola Adeyolanu, Stephen Okunade, Samuel Ogboye, Michael Elabiyi

“… The majority of metabolic activities occur in adiabatic environments; carbon uptake in soils serves as a signal for thermal heat fluxes, and plants can spontaneously generate heat during metabolic processes. …”
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Semi-automated data provenance tracking for transparent data production and linkage to enhance auditing and quality assurance in Trusted Research Environments by Katherine O'Sullivan, Milan Markovic, Jaroslaw Dymiter, Bernhard Scheliga, Chinasa Odo, Katie Wilde

“…Public Engagement and Involvement activities underpinned the methods to ensure the project and approaches met the public's trust for semi-automating data processing. …”
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BP-3 exposure at environmentally relevant concentrations induced male developmental reproductive toxicity via ER/CCL27/ROS pathway in mice by Hong-Mei Li, Yan-Rong Gao, Qing Chang, Xiu-Ying Pei, Jia-He Sun, Yu-Jia Lin, Ya-Nan Tian, Qiang-Wang, Bin Zhao, Heidi Qunhui Xie, Hui-Ming Ma, Hai-Ming Xu

“…BP-3 is the most widely used ultraviolet absorber, but its toxic effects and mechanisms far from being elucidated. …”
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What impact has the NIHR Academic Clinical Fellowship (ACF) scheme had on clinical academic careers in England over the last 10 years? A retrospective study by James Neilson, David Jones, Sally Clough, James Fenton, Helen Harris-Joseph, Leesa Rayton, Caroline Magee, Lisa Ann Cotterill

“…This study examines the impact of the ACF model, over its first 10 years, in developing clinical academic careers by tracking the progression of ACF trainees.Design Retrospective analysis of National Institute for Health Research (NIHR) ACF career progression. …”
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Niraparib restricts intraperitoneal metastases of ovarian cancer by eliciting CD36-dependent ferroptosis by Ning Jin, Yi-yu Qian, Xiao-fei Jiao, Zhen Wang, Xin Li, Wen Pan, Jin-kai Jiang, Pu Huang, Si-yuan Wang, Ping Jin, Qing-lei Gao, Dan Liu, Yu Xia

“…Although niraparib holds a pivotal role in the maintenance treatment of OC, its effect on suppressing metastases during primary intervention remains enigmatic. …”
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Bufalin targets the SRC-3/c-Myc pathway in chemoresistant cells to regulate metastasis induced by chemoresistance in colorectal cancer by Jinbao Chen, Chenqi Wu, Kun Yu, Jinpei Liu, Jiahua Yang, Wei Li, Xiaoxia Tang, Yihai Shi, Ke Xu, Yi Chen, Xiaoyu Qin

“…Moreover, the clinical drug cinobufacini and its main active monomer bufalin reduced liver metastasis of colorectal cancer caused by chemoresistance in vivo. …”
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Two sexually compatible monokaryons from a heterokaryotic Lentinula edodes strain respond differently to heat stress by Yuan Guo, Wenyu Jiao, Yajie Zhang, Meiting Tan, Qi Gao, Yu Liu, Shouxian Wang

“…For SP3, the differentially expressed genes (DEGs) were significantly enriched in Mitogen-Activated Protein Kinase (MAPK) signaling, cell cycle and sugar metabolism, whereas those DEGs for SP30 were enriched in glyoxylate and dicarboxylate metabolism, and protein processing. …”
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