Network Pharmacology and Experimental Validation of the Therapeutic Effect of Baji Capsule on LPS-Induced Osteoporosis by Li Q, Li D, Tian C, Liu X, Wang H, Liu H

“…The therapeutic effect of Baji capsule was evaluated by high-resolution micro-computed tomography (Micro-CT) and tissue section staining, serum inflammatory factor levels were assessed by ELISA, serum oxidative stress-related marker levels were determined by kits, and finally the mechanism was explored by network pharmacology and then verified by immunohistochemistry.Results: Micro-CT results showed that Baji capsule attenuated LPS-induced inflammatory bone loss.Baji capsule also reduced serum inflammatory factor levels and oxygen free radical production. …”
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ALGORITHMIC THINKING IN HIGHER EDUCATION: DETERMINING OBSERVABLE AND MEASURABLE CONTENT by Marian Byrka, Andrii Sushchenko, Volodymyr Luchko, Galina Perun, Victoria Luchko

Subjects: “…ICT…”
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Regulation of adipocyte differentiation and lipid metabolism by novel synthetic chromenes exploring anti-obesity and broader therapeutic potential by Kewalin Inthanon, Natthawut Wong-a-nan, Srisulak Dheeranupattana, Andres Garcia Guerra, Neal M. Davies, Chatchai Kesornpun, Sasithorn Sangher, Prasat Kittakoop

“…This modeling provides prospective anti-HIV activity, pharmacokinetic, metabolism, and permeability data, setting the groundwork for further investigation into these potential new chemical entities.…”
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Small molecule metabolites drive plant rhizosphere microbial community assembly patterns by Yanwei Ma, Heqi Wang, Yalong Kang, Tao Wen

“…In this study, we analyzed 108 plant samples and evaluated root traits, plant growth characteristics, soil enzyme activities, rhizosphere metabolites, and soil chemical properties to identify the primary determinants of rhizosphere community assembly. …”
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Evaluation of Rivaroxaban Exposure via Anti-Xa Levels During VTE Prophylaxis in Hospitalized Patients by Kaitlin Blotske PharmD, Toral Patel PharmD, BCPS, Toby Trujillo PharmD, FCCP, FAHA, BCPS, Matthew Marlar MLS (ASCP), Stuart Lind MD, Henry Kramer MD, Kathryn Hassell MD, Tyree H. Kiser PharmD, FCCM, FCCP, BCCCP, BCPS

“…The secondary outcomes assessing the relationship between rivaroxaban drug concentrations and time since administration, r 2  = 0.16 ( P  = .049), as well as time since administration of rivaroxaban and anti-Xa activity, r 2  = 0.15 ( P  = .066), were weakly correlated and showed a trend. …”
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Evaluation of prescribing practices and treatment failure for purulent skin and soft tissue infections in patients with obesity by Mackenzie L. Miller, Destiny M. Hughson, Noah D. Blower, Andrew P. Jameson, Lisa E. Dumkow

“…Sixty-seven percent of patients received MRSA-active therapy. Treatment failure was similar between those appropriately dosed (46.4%) versus under-dosed (54.4%) (P = 0.256), those receiving 5–7 days of therapy (47.1%) versus 10–14 days (54.4%) (P = 0.311), and those receiving MRSA-active therapy (52.2%) versus no MRSA therapy (45.5%) (P = 0.367). …”
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Impact of COVID-19 on the Air Quality over China and India Using Long-term (2009–2020) Multi-satellite Data by Manish Soni, Sunita Verma, Hiren Jethava, Swagata Payra, Lok Lamsal, Priyanshu Gupta, Janhavi Singh

“…Over the SE and NE China, both NO2 and SO2 levels decreased dramatically in 2020 from that of 2009–19, by more than 40% and 65%, respectively, because of both stricter regulations of emissions and less traffic activity due to reduced social and industrial activities during COVID-19 restrictions. …”
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Enteric-Coated Aspirin Induces Small Intestinal Injury via the Nrf2/Gpx4 Pathway: A Promising Model for Chronic Enteropathy by Zhang M, Xia S, Feng L, Han X, Zhang Y, Huang Y, Liu Y, Zhao K, Guan J, Tian D, Liao J, Yu Y

“…The mRNA and protein levels of inflammatory factors, tight junctions, and antioxidant defense-related genes were measured by qRT-PCR and Western Blot. The MPO activity, SOD activity and MDA content in serum were measured. …”
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Pre-injury frailty and clinical care trajectory of older adults with trauma injuries: A retrospective cohort analysis of A large level I US trauma center. by Oluwaseun Adeyemi, Corita Grudzen, Charles DiMaggio, Ian Wittman, Ana Velez-Rosborough, Mauricio Arcila-Mesa, Allison Cuthel, Helen Poracky, Polina Meyman, Joshua Chodosh

“…Compared to those classified as robust, those categorized as frail had 2.5 (95% CI: 1.86-3.23), 3.1 (95% CI: 2.28-4.12), and 0.3 (95% CI: 0.23-0.42) times the adjusted odds of trauma team activation, inpatient admission, and ED discharge, respectively. …”
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Changes in Tropospheric Nitrogen Dioxide Vertical Column Densities over Japan and Korea during the COVID-19 Using Pandora and MAX-DOAS by Yongjoo Choi, Yugo Kanaya, Hisahiro Takashima, Kihong Park, Haebum Lee, Jihyo Chong, Jae Hwan Kim, Jin-Soo Park

“…Abstract We investigated the impact of human activity during COVID-19 on the tropospheric nitrogen dioxide vertical column density (NO2 TropVCD) at three urban sites (Gwangju and Busan in Korea and Yokosuka in Japan) and one remote site (Cape Hedo in Japan) from Multi-Axis Differential Optical Absorption Spectroscopy (MAX-DOAS) and Pandora. …”
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Designing a Digital Transformation Model in the Offshore Oil and Gas Industry in Iran by Saeid Noadoust, Mostafa Safdari Ranjbar

“…Furthermore, among the most effective strategies to achieve this goal at the organizational level, stand cooperation with various bodies such as reputable information technology and communications companies, universities, and active startups in the digital technology sector. …”
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Optimization of corrosion resistance of AZ31 Mg alloy through hydration-driven interaction between quinolin-8-ol and plasma electrolytic oxidation-formed MgO layer by Mosab Kaseem, Talitha Tara Thanaa, Ananda Repycha Safira, Alireza Askari, Arash Fattah-alhosseini

“…This, combined with the increased number of active sites and enhanced surface area, allowed for extensive surface coverage by 8HQ, leading to the formation of a stable, flake-like protective layer that sealed the majority of pores on the PEO layer. …”
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HACE1 protects against myocardial ischemia–reperfusion injury via inhibition of mitochondrial fission in mice by Bang-Xia Liu, Juan Zheng, Zhan-Wei Tang, Lei Gao, Meng Wang, Ying Sun, Chen Chen, Heng-Chen Yao

“…On the other hand, HACE1 knockout further reduced superoxide dismutase (SOD) activity in the myocardium(P < 0.05), further supporting the findings. …”
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Behavioral representations within the endogenous dual attentional pathways during audiovisual integration processing by Zhongtian Guan, Mingli Yan, Miao He, Yubo Liu, Zhixi Zhang, Chunlin Li

“…The brain showed consistent activation in the frontal eye field, inferior parietal lobule, supplementary motor area, superior temporal gyrus, middle occipital gyrus and cuneus. …”
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Green nanoparticles synthesized from damask rose petals: Evaluation of their antioxidant, antimicrobial, anti-diabetic, anti-Alzheimer, and photocatalytic properties by Zeinab Alizadeh, Mohammad Fattahi, Alireza Farokhzad, Behvar Asghari, Soheil Yousefzadeh-Valendeh, Hadi Alipour, Javier Palazon

“…The G-ZnO NPs demonstrated the highest antioxidant activity (46.49 %). In terms of photocatalytic activity against methylene blue, G-ZnO NPs exhibited a higher degradation rate (61 %) than C-ZnO NPs1 and C-ZnO NPs2 (53.65 and 25.63 %). …”
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Comparative analysis of viability, proliferation, and mineralization potential of human pulp and osteoblastic cells exposed to different bioceramic endodontic sealers by Marcos Coelho Santiago, Gustavo Henrique de Oliveira Salles, Gustavo Gomes de Lima, Laudimar Alves de Oliveira, Loise Pedrosa Salles

“…The hDPCs viability and proliferation were low in the AHP-B group at 24h of exposure (NEOMTA-P ∼ BIO-C ∼ CT > AHP-B > MTA-F), distinct from the osteoblastic cells (NEOMTA-P ∼ AHP-B ∼ CT > BIO-C > MTA-F) and (proliferation: AHP-B > NEOMTA-P ∼ CT > BIO-C > MTA-F). …”
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Viable Ileosigmoid Knotting, A Very Phenomenon Finding and Rare Cause of Intestinal Obstruction: A Case Report and Literature Review by Beyene SA, Bogale NT, Abdinasir MM, Desalegne AZ, Wossen MA

“…There are different classification schemes of ileosigmoid knotting depending on the active component of the knot and based on the viability of the bowel and physiology of the patient. …”
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Barriers and enablers to implementing clinical practice guidelines in primary care: an overview of systematic reviews by Tao Wang, Xian-Liang Liu, Jing-Yu (Benjamin) Tan, Isabella Zhao

“…All the activities should be conducted by fully considering the social, cultural and community contexts to ensure the success and sustainability of CPGs implementation.…”
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The effect of a community-based health behaviour intervention on healthcare services use among people with type 2 diabetes in Nepal by Grish Paudel, Corneel Vandelanotte, M Mamun Huda, Padam Kanta Dahal, Lal Rawal

“…Methods: A cluster-randomised controlled trial was conducted in the Kavrepalanchowk and Nuwakot districts of Nepal, enrolling 481 people with clinically diagnosed type 2 diabetes, aged 30–70 years. A total of 30 study sites across two districts were randomly allocated into 15 intervention groups and 15 control groups. …”
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Perancangan dan Pembuatan Sistem Informasi Retensi Rekam Medis Rawat Jalan di Puskesmas Jenggawah Kabupaten Jember by Andri Permana Wicaksono, Muhaiminul Aziz, Feby Erawantini, Ida Nurmawati

“…The implementation of retention still aplied manually, caused retention activity did not run effectively and efficiently, and did not in accordance with the times. …”
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