Wnt/β-catenin signalling underpins juvenile Fasciola hepatica growth and development. by Rebecca Armstrong, Nikki J Marks, Timothy G Geary, John Harrington, Paul M Selzer, Aaron G Maule

“…Here, we identify five putative Wnt ligands and five Frizzled receptors in liver fluke transcriptomic datasets and find that Wnt/β-catenin signalling is most active in juveniles, the most pathogenic life stage. …”
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Exploration of techno-functional properties and metabolomic profile of Scleroderma texense (Phutuki Mushroom): a comparative study with Agaricus bisporus (white button mushroom) by Arun Kumar Gupta, Avinash Kumar Jha, Bindu Naik, Vijay Kumar, Sarvesh Rustagi, Milad Tavassoli

“…AB had a higher total phenolic content (5.49 mg GAE g−1) and DPPH free scavenging activity (68.07%), while ST, demonstrated superior total flavonoid content (4.66 mg QE g−1) and ABTS scavenging activity (87.69%). …”
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Evolution of CFD as an engineering science. A personal perspective with emphasis on the finite volume method by Runchal, Akshai Kumar

“…It was, however, the electronic computer in the middle of the 20th century that led to its birth and its widespread use. It has now become an invaluable tool for almost every sphere of human activity. …”
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Exploring Clec9a in dendritic cell-based tumor immunotherapy for molecular insights and therapeutic potentials by Zubair Hussain, Yueteng Zhang, Lu Qiu, Shanshan Gou, Kangdong Liu

“…The exceptional ability of Clec9a to cross-present dead cell-associated antigens and enhance both humoral and CTL responses makes it an optimal receptor for DC-based strategies aimed at strengthening antitumor immunity. …”
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Evaluation of the digital diabetes prevention programme pilot: uncontrolled mixed-methods study protocol by William Henley, Elizabeth Murray, Kerry Daff, Anthi Lavida, Jenny Irwin, Jonathan Valabhji

“…Secondary outcomes include use of the intervention, satisfaction, physical activity, patient activation and resources needed for successful implementation. …”
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‘Bulun in Winter Is So Sad’: A. Bogolepov about Everyday Life in Polar Yakutia, 1913–1916 by Lilia I. Vinokurova, Alexander A. Suleymanov, Svyatoslav I. Fedorov

“…The article introduces an unknown manuscript by A. Bogolepov titled ‘Bulun Village of Verkhoyansk District (Yakutsk Oblast)’ and compiled during an exile to the isolated Arctic locality of Yakutia. …”
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Selective epithelial expression of KRASG12D in the Oncopig pancreas drives ductal proliferation and desmoplasia that is accompanied by an immune response by Carlos P. Jara, Al-Murtadha Al-Gahmi, Audrey Lazenby, Michael A. Hollingsworth, Mark A. Carlson

“…These findings highlight the potential for site-specific activation of oncogenes in large animal models of epithelial tumors, with the ability to induce stromal alterations reminiscent of human PDAC.…”
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Long non-coding RNAs modulate glutathione metabolism gene expression and tolerance to Pb stress in root tissue of endophyte-infected rice seedling by He-Fei Sun, Xin-Nan Wang, Ya-Nan Li, Lan-Lan Wang, Yue-Ying Li, Lian-Ju Ma, Xue-Mei Li

“…DEmRNAs were most significantly enriched in glutathione metabolism, thereinto detected total glutathione, reduced and oxidized glutathione contents, glutathione S-transferase and glutathione reductase activities were significantly increased after 5 d of treatment. …”
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Design, synthesis and biological evaluation of buthutin derivatives as cardioprotective agents by Yuan Liu, Fa-Qi Wang, Xin-Hao Hua, Shu-Han Yang, Li-Ning Wang, Yun-Sheng Xu, Chen-Yue Shao, Xiang-Bo Gou, Yu-Ming Liu

“…Meanwhile, compounds 9k, 9m, and 9o showed the significant NHE-1 inhibitory activities on H9c2 cardiomyocyte, all with a dpHi/min value less than 0.23. …”
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Design and evaluation of bromelain-encapsulated alginate beads reinforced with gum Arabic: Formulation, characterization, and stability in simulated gastrointestinal conditions by Methavee Peanparkdee, Phornphimon Janchai, Tanwarat Aksornsri, Pilanee Vaithanomsat

“…Encapsulation in SG1 resulted in the highest protein release (105.38 %) and antioxidant activity (36.41 mmol Trolox/g bead for FRAP, 6.34 mmol Trolox/g bead for ABTS) after intestinal digestion. …”
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The analysis of project-based learning models implementation on student motivation and learning achievement by Amara Mery Athaya, Mira Kusmiati, M. Azhar Faturachman

“…Learning activities are now centered not only on teachers but also on students who actively participate in the process. …”
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Correlation between intestinal stem cell niche changes and small bowel crypt failure in patients with treatment-naïve celiac disease by Prasenjit Das, Sudha Battu, Lalita Mehra, Alka Singh, Muzaffar Ahmad, Ashish Agarwal, Ashish Chauhan, Anam Ahmad, Sreenivas Vishnubhatla, Siddhartha Datta Gupta, Vineet Ahuja, Govind Makharia

“…However, the Ki67 proliferation index, expressions of WNT-activator RSPO1, and position-4 cell marker Bmi1 did not significantly alter in patients’ biopsies as compared to controls (P = 0.001). …”
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A Comparison of Resting Scapular Posture and the Davies Closed Kinetic Chain Upper Extremity Stability Test by John D Heick, Jenna Haggerty, Robert C Manske

“…Functional performance testing is used to objectively measure activities that simulate various desired activities. …”
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Correlation among blastocoel fluid DNA level, apoptotic genes expression and preimplantation aneuploidy by Fattaneh Khajehoseini, Zahra Noormohammadi, Poopak Eftekhari-Yazdi, Hamid Gourabi, Reza Pazhoomand, Shirzad Hosseinishenatal, Masood Bazrgar

“…We observed that the correlation between apoptotic activity and BF-DNA levels is influenced by the embryo’s ploidy status. …”
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Novel architecture of ternary ZnO/PMA/AgI heterojunctions towards boosted visible-light photocatalytic destruction of antibiotics by Yossor R. Abdulmajeed, Saad H. Ammar, Nada D. Ali, Fatma D. Ali, A. Al-Farraji, Marwa A. Lafta

“…Besides, after six cyclic degradations, the degradation efficiency of the ZnO/PMA/AgI photocatalyst for LEV stayed about 90%, demonstrating its superb photocatalytic stability.…”
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Focal adhesion kinase promotes aerobic glycolysis in hepatic stellate cells via the cyclin D1/c-Myc/MCT-1 pathway to induce liver fibrosis by Tao Huang, Ming-Yu Zhou, Gao-Liang Zou, Rui-Han Hu, Lu Han, Qing-Xiu Zhang, Xue-Ke Zhao

“…The migration, proliferation and aerobic glycolysis of LX-2 cells after stimulation and activation by transforming growth factor beta-1 (TGF-β1) or suppression by PF562271 was assessed in vitro. …”
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Business Development of The Ecotourism of Javan Gibbon: A Marketing Mix Strategy at Gede Pangrango National Park by Fandawa Saputra, Tutut Sunarminto, Harnios Arief, Khairiyah Kamilah

“…Respondents also agree that this ecotourism activity also support the long-term survival of this endangered species. …”
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Cumulative Effects of a Week’s Training Loads on Shoulder Physical Qualities and Wellness in Competitive Swimmers by Matias Yoma, Lee Herrington, Tanya Anne Mackenzie

“…LVG and HVG participants decreased active shoulder ER ROM on dominant (p= 0.002; p= 0.006) and nondominant sides (p= 0.001; p= 0.004), displayed increased muscular soreness (p= 0.001; p= 0.007) and worsened overall wellness (p< 0.001; p= 0.010). …”
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Analytical hierarchy process as a tool supporting a decision-making for assessment of the risk of transboundary infectious animal disease introduction to the Russian Federation an... by N. V. Lebedev, A. S. Igolkin, K. N. Gruzdev, D. G. Spirin, M. A. Farukh, N. V. Ermilov, G. G. Eremin

“…Its export potential is actively growing. Already, up to 10% of agricultural products are exported to foreign markets. …”
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Determinants of Adverse Perinatal Outcomes in Ibadan, Nigeria: The influence of maternal lifestyle. by Ikeola A Adeoye, Chioma O Unogu, Kofoworola Adediran, Babatunde M Gbadebo

“…Prevalence of APO was 26.7%, 95%CI (24.4-29.1); low birth weight - 8.5%, 95%CI (7.0-10.1) preterm delivery 14.8%, 95% CI (12.9-16.7); birth asphyxia 16.3%, 95%CI (14.0-18.9). …”
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