Effect of Lingnan Painless Apitherapy combined with McKenzie Therapy on Patients with Lumbar Disc Herniation by Hongbo WU, Xinghua CHEN, Ruike ZHANG, Qinglu LUO, Yongming CHENG

“…Objective:To observe the clinical efficacy of Lingnan painless apitherapy combined with McKenzie therapy on patients with lumbar disc herniation(LDH).Methods:A total of 80 patients with LDH who were treated in the department of rehabilitation medicine of the fifth affiliated hospital of Guangzhou medical university from February 2019 to June 2020 were randomly divided into the control group and the observation group according to the random number table method, with 40 cases in each group.The control group received magnetic thermal-vibration therapy and McKenzie therapy.The Japanese magnetic thermal-vibration therapy instrument(TM-3200)was used in the magnetic thermotherapy, the appropriate intensity(high, hot, warm and low temperature)was selected according to the patient's feeling and symptoms, 20 minutes each time, once a day, seven times a week, continuous treatment for two weeks.In addition, the patients with LDH received McKenzie therapy, which was assisted by the therapist or the patient actively completed the flowing training, such as prone position stretching, prone position stretching combined with compression, standing position lateral movement and so on.Each step rested for one minute, once every two days, continuous treatment for two weeks.The observation group received Lingnan painless apitherapy on the basis of treatment in the control group after half an hour's rest.Before treatment, the patients were given apitherapy tolerance test, performing apitherapy with one bee on each Zusanli acupoints on both sides.After apitherapy for 15 minutes, if there was no adverse reaction, the patients were given painless apitherapy with a quiet and comfortable environment, every other day.In this treatment, both sides of Huatuo Jiaji acupoints on the lumbar spinous processes were selected, and Huatuo Jiaji acupoints on both sides of the 5th lumbar spinous process were selected in the first treatment, one acupoint on the left and one on the right.After that, two acupoints were added each time, and each acupoint was treated by one bee.According to the order of Jiaji points on the 4th, 3rd, 2nd and 1st lumbar vertebrae, the number of bee needles increased to 10 bees.Before treatment and two weeks after treatment, visual analogue scales(VAS)was used to evaluate the pain degree, Oswestry disability index(ODI)was used to assess the lumbar spine dysfunction, and TCM syndrome score was used to evaluate the therapeutic effect, and the clinical efficacy was evaluated by <italic>the diagnosis and curative effect standards of TCM diseases</italic>.Results:Before treatment, there was no significant difference in the VAS score, ODI score and TCM syndrome score between the observation group and the control group(<italic>P</italic>&gt;0.05).Compared with treatment before, the VAS score, ODI score and TCM syndrome score after treatment for two weeks of the two groups were significantly reduced, with a statistically significant difference(<italic>P</italic>&lt;0.05).Compared with the control group, the VAS score and TCM syndrome score of the observation group were lower than those of the control group, with a statistically significant difference(<italic>P</italic>&lt;0.05), but there was no considerable difference in ODI score between the two groups(<italic>P</italic>&gt;0.05), and the clinical efficacy of the observation group(95%)was significantly higher than that of the control group(80%)(<italic>P</italic>&lt;0.05).Conclusion:Lingnan painless apitherapy combined with McKenzie therapy can significantly improve the pain degree and lumbar spine dysfunction of patients with LDH, which have a good effect and it is worthy of clinical promotion.However, it's necessary to develop large-sample randomized controlled trials and follow-up, to provide more reliable basis for clinical treatment of LDH.…”
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Voacanga africana-artesunate and Voacanga africana-amodiaquine combinations as effective anti-plasmodial agents in mice by Daniel Ampomah Frimpong, Aliu Moomin, Samuel Asare Nkansah, Aaron Opoku Antwi, Abubakar Ibn Sidik, Paa Kofi Tawiah Adu-Gyamfi, Kwesi Boadu Mensah

“…Background: Malaria is a global health problem due to its high incidence of morbidity and mortality, especially in children and pregnant women. …”
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Assessment of post-partum physical exercise practice and its associated factors among women in postpartum period, in West Wollega zone, Oromia, Ethiopia by Tegegne Yadeta, Daniel Belema, Seifedin Ahmad, Nurye Sirage, Abubeker Seid Ali, Kedir Ali, Ali Yimer

“…Incorporating regular physical activity during this phase has demonstrated the potential to mitigate the chances of chronic metabolic disorders. …”
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Factors associated with the discontinuation of modern contraceptive methods among lactating women in nine West African high-fertility countries: findings of the most recent demogra... by Abou Coulibaly, Adama Baguiya, Denise Kpebo, Augustin Zango, Halima Tougri, Franck Garanet, Seni Kouanda

“…Moreover, women who were not sexually active (aPR = 2.11; 95% CI [1.75–2.54]; p < 0.001) and those who wanted children within two subsequent years (aPR = 1.84; 95% CI [1.36–2.48]; p < 0.001) were more likely to discontinue contraception. …”
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Modalities for the treatment of primary open-angle glaucoma by Zh.G. Oganezova, S.V. Simonova

“…Clinical trials on brimonidine demonstrate its direct neuroprotective effect which is independent of its IOP-lowering effect (i.e., cell survival improves even in ocular hypertension until IOP is well-controlled). …”
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Clinical observation on effect of Chinese herbal fumigation and washing with Xiwenjing Huoxue Tongluo Decoction on limb numbness after chemotherapy for malignant tumor (中药熏洗温经活血通络方... by WU Ying (吴莹), TIAN Weili (田薇莉)

“…All patients were treated with conventional rehabilitation training, and those in the observation group were Chinese herbal fumigation and washing additionally with Xiwenjing Huoxue Tongluo Decoction, the course of treatment for both groups was 1 month. The scores of Activity of Daily Living and Simplified Mc Gill Pain Questionnaire( SF-MPQ) were observed before and after treatment. …”
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Comparative Analysis of Biochemical Parameters, Thermal Behavior, Rheological Features, and Gelling Characteristics of Thai Ligor Hybrid Chicken and Broiler Meats by Ngassa Julius Mussa, Chantira Wongnen, Warangkana Kitpipit, Worawan Panpipat, Mingyu Yin, Siriporn Riebroy Kim, Manat Chaijan

“…Results showed that BC meat exhibited higher ultimate pH after 24 h, Ca²⁺-ATPase activity, and trichloroacetic acid (TCA)-soluble peptide content compared to LC meat (<i>p</i> < 0.05). …”
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A Dynamic Adaptive Ensemble Learning Framework for Noninvasive Mild Cognitive Impairment Detection: Development and Validation Study by Aoyu Li, Jingwen Li, Yishan Hu, Yan Geng, Yan Qiang, Juanjuan Zhao

“…ResultsThe experimental results indicate that the proposed MCI detection framework achieved classification accuracies of 88.4%, 85.5%, and 84.5% on the development, internal test, and external test datasets, respectively. The area under the curve for the binary classification task was 0.945 (95% CI 0.903-0.986), 0.912 (95% CI 0.859-0.965), and 0.904 (95% CI 0.846-0.962) on these datasets. …”
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Association of lipid accumulation product index with self-reported diabetes among residents aged 18 – 44 years in Hebei province, 2020: a surveillance data analysis by Qi QI, Lijuan TANG, Yuhuan LIU, Jinchai GAO, Xiuli NIU, Qianyu LI, Shifan WANG, Xiaoli LIU, Ze CUI

“…After adjusting for age, ethnicity, education level, marital status, employment, annual household income per capita, place of residence, smoking, alcohol consumption, and physical activity, unconditional multivariate logistic regression analysis showed that, compared with those with LAP index in the lowest quartile, male residents with LAP index in the second, third, and highest quartiles had an increased risk of self-reported diabetes, with odds ratios (95% confidence interval) of 7.78 (2.33, 26.01), 12.74 (3.90, 41.63), and 34.38 (10.75, 109.93), respectively, while female residents with LAP index in the highest quartile had an increased risk of self-reported diabetes (odds ratio = 11.32, 95% confidence interval: 4.76, 26.96) compared with those with LAP index in the lowest quartile. …”
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Nano-Zinc Oxide Can Enhance the Tolerance of Apple Rootstock M9-T337 Seedlings to Saline Alkali Stress by Initiating a Variety of Physiological and Biochemical Pathways by Jietao Zhai, Xulin Xian, Zhongxing Zhang, Yanxiu Wang

“…ZnO NPs can balance the osmotic adjustment system by increasing the contents of soluble protein (SP), soluble sugar (SS), proline (Pro) and starch, and can also enhance the activities of enzymatic (SOD, POD, and CAT) and non-enzymatic antioxidant enzymes (APX, AAO, GR, and MDHAR) to enhance the scavenging ability of reactive oxygen species (H₂O₂, O₂^•−), ultimately reducing oxidative damage; ZnO NPs promoted the growth of M9-T337 seedlings under saline alkali stress by synergistically responding to auxin (IAA), gibberellin (GA₃), zeatin (ZT) and abscisic acid (ABA). …”
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Effectiveness of Virtual Reality Training in Improving Outcomes for Dialysis Patients: Systematic Review and Meta-Analysis by Xin Kang, Yiping Zhang, Chaonan Sun, Jiaxin Zhang, Zhe Che, Jinhui Zang, Rongzhi Zhang

“…However, VR training did not yield significant differences in gait speed, balance, or functional tests (Ten Sit-to-Stand Test, Five Sit-to-Stand Test, Sixty Sit-to-Stand Test, Timed Up and Go Test, and fatigue) compared with control groups. …”
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Skema Kredibilitas Sertifikat Berbasis Ilearning Gamifikasi Blockchain pada Kampus Merdeka by Qurotul Aini, Nur Azizah, Rahmat Salam, Nuke Puji Lestari Santoso, Fitra Putri Oganda

“…The final result of this research is to build new normality in the successful implementation of MBKM and create an ecosystem of interactive student activity hours, hone soft skills, and build critical thinking by carrying out the iLearning learning model based on Blockchain gamification techniques (iLearning Gamichain).  …”
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Аssessment of the prospects for growing forest crops of European larch in the Eastern Forest-Steppe of Ukraine by Svitlana Raspopina, Maksim Didenko

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A KSHV RNA-binding protein promotes FOS to inhibit nuclease AEN and transactivate RGS2 for AKT phosphorylation by Vladimir Majerciak, Beatriz Alvarado-Hernandez, Yanping Ma, Shivalee Duduskar, Alexei Lobanov, Maggie Cam, Zhi-Ming Zheng

“…FOS binds a conserved AP-1 site in the RGS2 promoter and enhances RGS2 expression to phosphorylate AKT. …”
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Analisis Komparatif Keamanan Aplikasi Pengelola Kata Sandi Berbayar Lastpass, 1Password, dan Keeper Berdasarkan ISO/IEC 25010 by Whisnu Yudha Aditama, Ira Rosianal Hikmah, Dimas Febriyan Priambodo

“…Meanwhile, the 1Password application is superior in proving the identity of the user as claimed and is able to log every user activity into a log. and the Lastpass application has the same advantages as Keeper application in the duration of keeping logs in the system. …”
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Male sex ratio of red tilapia Oreochromis sp. after soaking in different concentrations of coconut milk at larvae stadia by Fajar Maulana, Agus Oman Sudrajat, Andre Permana, Lina Mulyani, Harton Arfah

“…As the use of the 17α-methyltestosterone synthetic hormone for masculinization activities has been limited, natural ingredients are required as a substitute, namely coconut milk. …”
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Serum Lactate Dehydrogenase Is a Novel Predictor for the Severity in the Patients With MAFLD: A Cross-Sectional Study in Hefei, China by Yu L, Bao S, Zhu F, Xu Y, Zu F, Liu Y, Jiang R, Chen S, Chen W

“…MAFLD was defined as the presence or absence of fatty liver disease as suggested by histologic biopsy of liver or postoperative pathology slides, or even hematology, and meets one of the following three conditions: overweight or obesity, T2DM, and metabolic dysfunction (MetS). Serum LDH activity levels were measured in 885 patients, and logistic regression was used to analyze the relationship between LDH and metabolic syndrome and the severity of MAFLD.Results: In the study cohort of 855 obese patients, 604 (70.6%) had MetS. …”
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Adaptación y dimensionalidad de la escala DOCS en el contexto organizacional costarricense: aplicación de la entrevista cognitiva y el análisis factorial confirmatorio/ Adaptation... by Tómas Vargas-Halabí, Ronald Mora-Esquivel

“…It was then applied in two samples, with similar characteristics, but belonging two different populations: a) 314 students drawn from 445 active students enrolled in Master’s Programs (MBA and Project Management) at the Costa Rican Institute of Technology, whose prerequisite for admission stipulates experience in professional positions, preferably supervisory and managerial, and; b) 368 managers drawn from a sampling frame of 1743 companies from various business associations. …”
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Dose-response associations of device-measured sleep regularity and duration with incident dementia in 82391 UK adults by Wenxin Bian, Raaj K. Biswas, Matthew N. Ahmadi, Yu Sun Bin, Svetlana Postnova, Andrew J. K. Phillips, Nicholas A. Koemel, Jean-Philippe Chaput, Shantha M. W. Rajaratnam, Peter A. Cistulli, Emmanuel Stamatakis

“…When we dichotomized sleep regularity, those in the higher sleep regularity group (SRI ≥ 70) had an HR of 0.74 (95%CI 0.63, 0.87) compared to those with lower sleep regularity (SRI < 70). …”
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Evaluasi Tata Kelola Teknologi Informasi PT Pertamina Hulu Energi Menggunakan Framework COBIT 4.1 Fokus Domain Plan and Organise (PO) dan Acquire and Implement (AI) Khusus pada Imp... by Muhammad Ghiffari, Yusi Tyroni Mursityo, Suprapto Suprapto

“…Based on the results of the previous year's assessment, the ICT & DM division has already reached IT-maturity level 3 (Defined Process). …”
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