Principles, barriers and enablers to agroecological animal production systems: a qualitative approach based on five case studies by B. Dumont, C. Barlagne, P. Cassart, J.E. Duval, A. Fanchone, J-L. Gourdine, O. Huguenin-Elie, Y. Kazakova, J. Klötzli, A. Lüscher, E. Oteros-Rozas, D. Pomies, M.G. Rivera Ferre, W.A.H. Rossing, V. Stefanova, A. Swartebroeckx, C. Zagaria

“…Though we could observe activities related to each agroecological principle in each case study, the relative importance of each principle differed. …”
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Molecular and cellular aspects of the impact of secondary metabolites from common barberry and hybrid goat’s rue on the HeLa cell line by E. Yu. Zlatnik, Ya. S. Enin, O. N. Burov, E. S. Bondarenko, A. B. Sagakyants, D. S. Kutilin, Yu. V. Dzigunova, O. G. Ishonina, E. V. Shalashnaya, N. D. Ushakova

“…Terpenoids 4-dihydroxy-2,5-dimethylfuran-3(2H)-one and 2,2,8-trimethyldecahydroazulene-5,6-dicarbaldehyde, when exposed to the HeLa line, caused an increase in the copy number variation and expression of the CASP9, CASP3 loci, which are among the main activators of apoptosis. They also influenced the expression of TP53 and MDM2 loci.…”
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FAM134B-mediated endoplasmic reticulum autophagy protects against cisplatin-induced spiral ganglion neuron damage by Fan Wang, Yue Xu, Yajie Wang, Qian Liu, Yanan Li, Weiwei Zhang, Huiming Nong, Junhong Zhang, Hao Zhao, Huaqian Yang, Lingchuan Guo, Jianfeng Li, Jianfeng Li, Hong Li, Qianqian Yang

“…Results showed decreases in the number of SGNs and FAM134B expression, as well as increases of ROS level, ER stress, ER-phagy, and apoptosis after Cis stimulus. Inhibiting autophagy increased the expression of FAM134B, and aggravated Cis-induced SGN damage, while the opposite changes were observed when autophagy was activated. …”
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Evaluation of pitomba extract as a natural antioxidant in fresh sausages: Effects on physicochemical properties and lipid oxidation by Taline Fiorucci da Silva, Flávia Aparecida Reitz Cardoso, Nathália Leticia Hernandez Brito, Sahra Gadia Trelha, Stefanie Calisto Casarin, Leila Larisa Medeiros Marques, Adriana Aparecida Droval

“…This method demonstrated strong antioxidant activity, surpassing traditional solvents, highlighting its potential as a natural alternative for bioactive compound extraction. …”
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Fusion of EEG and EMG signals for detecting pre-movement intention of sitting and standing in healthy individuals and patients with spinal cord injury by Chenyang Li, Chenyang Li, Yuchen Xu, Tao Feng, Tao Feng, Minmin Wang, Minmin Wang, Minmin Wang, Xiaomei Zhang, Li Zhang, Li Zhang, Ruidong Cheng, Weihai Chen, Weihai Chen, Weidong Chen, Weidong Chen, Shaomin Zhang, Shaomin Zhang, Shaomin Zhang, Shaomin Zhang

“…IntroductionRehabilitation devices assist individuals with movement disorders by supporting daily activities and facilitating effective rehabilitation training. …”
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Involvement of Pneumocystis jirovecii in infectious and other diseases in children and adults with immunosuppression of various origin by Rybalkina T.N., Karazhas N.V., Kornienko M.N., Avetisyan L.R., Boshyan R.E., Pulnova N.L., Kabikova O.F., Ivanova M.Yu., Chereshneva E.V.

“…To assess the risk of infection with P. jirovecii, pneumocystosis and its spread by healthcare workers. Materials and Methods. …”
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Assessing intrinsic capacity for person‐centred HIV care: a cross‐sectional study in ageing populations in Malaysia and Hong Kong by Reena Rajasuriar, Syaza Hisham, John Son Lim, Jean Yi Cheong, Wen Ying Ho, Siew Hwei Yap, Nurul Syuhada Zulhaimi, Malinee Neelamegam, Catherine Cheung, Vivian Wong, Ruhana Che Yusof, Kejal Hasmukharay, Shahrul Bahyah Kamaruzzaman, Sharifah Faridah Syed Omar, Meng Li Chong, Pui Li Wong, Grace Chung‐Yan Lui

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Relation among zootechnical performance, biochemical indicators, water quality, and small invertebrates (zooplankton) abundance reared in biofloc-supplemented systems by Ahmed Said Al-Souti, Marwa M. Zaher, Amr M. Helal, Dina T. Meshhal, Mansour D. H., Afify D. G. Al-Afify, Mohamed M. Rafaey, Abeer El-Saharty, Ehab El-Haroun, Marian G. Nassif, Abdallah Tageldein Mansour, Abdallah Tageldein Mansour, Mohamed Ashour

“…The fish reared in groups T0 and T1 showed the highest significant urea content and the highest concentrations of liver function enzyme activities. Interestingly, compared to all groups, T3 achieved the best feed conversion ratio (FCR) value (1.68). …”
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Clinical validation of an artificial intelligence-based decision support system for diagnosis and risk stratification of heart failure (STRATIFYHF): a protocol for a prospective, m... by Prithwish Banerjee, Guy A MacGowan, Frans H Rutten, Iacopo Olivotto, Petar M Seferović, Jonathan Mant, Djordje G Jakovljevic, Oscar Fernandez, Josep Darbà, Nduka C Okwose, Jose Zamorano, Duncan Edwards, David Sinclair, Lazar Velicki, Amy Groenewegen, Lars S Maier, Dimitris Fotiadis, Sarah Jane Charman, Annamaria Del Franco, Maria Tafelmeier, Andrej Preveden, Cristina Garcia Sebastian, Amy S Fuller, Anne Pauline Nelissen, Petros Malitas, Aikaterini Zisaki, Zoran Bosnic, Petar Vracar, Fausto Barlocco, Marta Jiménez-Blanco Bravo, Nenad Filipovic, Bano Fatima, Williams Kate, Fornaro Alessandra, Milovancev Aleksandra, Ascanio Meritxell, Aguera Ainoa, Pičulin Matej, Flis Borut, Boucharas Dimitrios, Manousos Dimitris, Tsiknakis Manolis, Kassiotis Thomas, Sustersic Tijana, Milicevic Bogdan, Hobbs FD Richard, Kaagman Onno

“…Accurate risk stratification and early diagnosis of HF are challenging as its signs and symptoms are non-specific. We propose to address this global challenge by developing the STRATIFYHF artificial intelligence-driven decision support system (DSS), which uses novel analytical methods in determining the risk, diagnosis and prognosis of HF. …”
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Oncolytic virus OH2 extends survival in patients with PD-1 pretreated melanoma: phase Ia/Ib trial results and biomarker insights by Juan Li, Xuan Wang, Li Zhou, Jun Guo, Lu Si, Bixia Tang, Chuanliang Cui, Xiaoting Wei, Xinan Sheng, Siming Li, Zhihong Chi, Lili Mao, Bin Lian, Xieqiao Yan, Yan Kong, Caili Li, Xiangyong Gu, Binlei Liu, Hui Tian, Han Hu

“…A phase Ia/Ib clinical trial in China was conducted in patients with unresected stage III–IV melanoma, the majority of whom had the acral type, to assess the safety and preliminary efficacy of OH2.Methods The trial enrolled patients with histologically confirmed unresectable stage III or advanced stage IV melanoma. …”
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A personal sensing technology enabled service versus a digital psychoeducation control for primary care patients with depression and anxiety: a pilot randomized controlled trial by Colleen Stiles-Shields, Karen M. Reyes, Tanvi Lakhtakia, Shannon R. Smith, Olga E. Barnas, Elizabeth L. Gray, Charles J. Krause, Kaylee P. Kruzan, Mary J. Kwasny, Zara Mir, Sameer Panjwani, Steven K. Rothschild, Lisa Sánchez-Johnsen, Nathan W. Winquist, Emily G. Lattie, Nicholas B. Allen, Madhu Reddy, David C. Mohr

“….), informed by behavioral activation and using passive sensing technology to provide behavioral “insights” and target behaviors associated with mental health symptoms, alongside lay-provider coaching, or (2) Control: the Mood Education mobile app (ME), containing static psychoeducational resources designed to target mental health symptoms. …”
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Dietary Se-enrich Cardamine violifolia supplementation decreases lipid deposition and improves antioxidant status in the liver of aging laying hens by Mengke Yan, Xin Cong, Hui Wang, Kun Qin, Yuhui Tang, Xiao Xu, Dan Wang, Shuiyuan Cheng, Yulan Liu, Huiling Zhu

“…Selenium (Se)-enriched Cardamine violifolia (SEC) is known for its excellent antioxidant function. The objective of this study was to evaluate the effects of SEC on antioxidant capacity and lipid metabolism in the liver of aged laying hens. …”
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Early Outcomes from Proton Craniospinal Irradiation for Leptomeningeal Metastasis From Solid Tumors by Keng Lam, MD, Lewis F. Nasr, MD, Clark R. Andersen, MS, Kathryn E. Marqueen, MD, Jing Li, MD, PhD, Chenyang Wang, MD, Thomas H. Beckham, MD, PhD, Nazanin K. Majd, MD, PhD, Ashley E. Aaroe, MD, Monica Loghin, MD, Barbara J. O'Brien, MD, Susan L. McGovern, MD, PhD

“…Median overall survival was 13.7 months (95% confidence interval [CI], 11.2 to not reached), and median progression-free survival was 6.5 months (95% CI, 4.9-12.8). …”
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Long-term functioning status of COVID-19 survivors: a prospective observational evaluation of a cohort of patients surviving hospitalisation by Linamara Rizzo Battistella, Felipe Fregni, Marta Imamura, Vinicius Delgado Ramos, Lucas Ramos De Pretto, Simon K H A A Van Cauwenbergh, Sabrina Saemy Tome Uchiyama, Denise Matheus, Flavia Kuhn, Ana Alice Amaral de Oliveira, Gabriella Souza Naves, Aline Rossetti Mirisola, Fernando de Quadros Ribeiro, Andre Tadeu Sugawara, Mauricio Cantarino, Rafael Andrade Santos Antunes Cavalca, Vanessa Pagano, Melina Valentim Marques, Elizabeth Mendes da Silva, Alessandra Pereira Gomes

“…With a mean of 6.56 (SD: 1.58; 95% CI: 6.45 to 6.67) months after hospital discharge, 70.86% (567 of 800) reported limited daily activities, which were severe in 5.62% (45 of 800). …”
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Spatial Distribution of Tsetse Flies and Trypanosome Infection Status in a Vector Genetic Transition Zone in Northern Uganda by Robert Opiro, Okello Allele Moses, Robert Opoke, Francis A. Oloya, Esther Nakafu, Teresa Iwiru, Richard Echodu, Geoffrey M. Malinga, Joel L. Bargul, Elizabeth A. Opiyo

“…Therefore, appropriate mitigation measures should be instituted targeting tsetse and other biting flies that may play a role as disease vectors, given the predominance of T. vivax in the tsetse samples.…”
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Development of a Cationic Polymeric Micellar Structure with Endosomal Escape Capability Enables Enhanced Intramuscular Transfection of mRNA-LNPs by Siyuan Deng, Han Shao, Hongtao Shang, Lingjin Pang, Xiaomeng Chen, Jingyi Cao, Yi Wang, Zhao Zhao

“…The membrane-destabilization activity of the cPMs was evaluated by a hemolysis assay. …”
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Expression of the NUP153 and YWHAB genes from their canonical promoters and alternative promoters of the LINE-1 retrotransposon in the placenta of the first trimester of pregnancy by V. V. Demeneva, E. N. Tolmacheva, T. V. Nikitina, E. A. Sazhenova, S. Yu. Yuriev, A. Sh. Makhmutkhodzhaev, A. S. Zuev, S. A. Filatova, A. E. Dmitriev, Ya. A. Darkova, L. P. Nazarenko, I. N. Lebedev, S. A. Vasilyev

“…This study aimed to analyze the expression of the NUP153 and YWHAB genes, highly active in the placenta, from canonical and alternative LINE-1 promoters in the germinal part of the placenta of spontaneous and induced abortions. …”
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Case Report: Efficacy and safety of recombinant growth hormone therapy in a girl with Loeys–Dietz syndrome by Kamil Dyrka, Aleksander Jamsheer, Michal Bartecki, Waldemar Bobkowski, Malgorzata Pawelec-Wojtalik, Justyna Rajewska-Tabor, Andzelika Tomaszewska, Justyna Balcerzak, Zuzanna Aniol, Marek Niedziela, Monika Obara-Moszynska

“…In addition to its growth-promoting effect, the wide influence of GH on the human body, metabolic status, and muscle strength is also significant. …”
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Definisanje optimalnog proizvodnog miksa u dekarbonizovanom energetskom sistemu by Vladan Ristić, Miljan Žikić, Dragana Vujanović, Ivan Trkulja, Ognjen Mijušković

“…Smatraće se da je zbir instalisanih snaga ovih izvora konstantan, dok će procenat sa kojim svaka od elektrana učestvuje u toj snazi biti variran sa ciljem definisanja onog odnosa instalisanih snaga pri kome dolazi do najmanjih varijacija zbirne snage proizvodnje u periodu od godinu dana, sa satnom rezolucijom. …”
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Surveillance of Mycoplasma agassizii in Texas tortoises (Gopherus berlandieri) for translocation with emphasis on treatment and recovery by Christin A. Moeller, Saren Perales, Wraith Rodriguez, Alynn M. Martin, Cord B. Eversole, Sandra Rideout-Hanzak, Paul Crump, Clayton D. Hilton, Scott E. Henke

“…Eighteen tortoises from the donor site (10.5%) and 2 from the recipient site (8.7%) displayed clinical signs (i.e., clear serous nasal discharge, conjunctivitis, and palpebral edema) consistent with Mycoplasmal URTD upon initial collection, even though all polymerase chain reaction (PCR) results were negative for active shedding of Mycoplasma agassizii. …”
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