O-GlcNAcylation attenuates ischemia-reperfusion-induced pulmonary epithelial cell ferroptosis via the Nrf2/G6PDH pathway by Liuqing Yang, Hexiao Tang, Jin Wang, Dawei Xu, Rui Xuan, Songping Xie, Pengfei Xu, Xinyi Li

“…Furthermore, both the chromatin immunoprecipitation (ChIP) assay and the dual-luciferase reporter assay indicated that Nrf2 could bind with translation start site (TSS) of glucose-6-phosphate dehydrogenase (G6PDH) and promote its transcriptional activity. …”
Get full text

Crystalloid resuscitation is associated with decreased treatment delays and improved systolic blood pressures in a blood-constrained setting by Melissa Carvalho, Alain Chichom-Mefire, Catherine Juillard, S Ariane Christie, Rasheedat Oke, Thompson Kinge, Jean-Gustave Tsiagadigui, Mbiarikai A Mbianyor, Mark T Yost, Matt Driban, Fanny Nadia Dissak Delon, Richard Njock, Daniel Nkusu

“…We hypothesized that more patients would receive crystalloid-based (CB) resuscitation with a faster time to administration than blood product (BL) resuscitation.Methods We included patients enrolled between 2017 and 2019 in the Cameroon Trauma Registry (CTR). Patients presenting with hemorrhagic shock (systolic blood pressure (SBP) <100 mm Hg and active bleeding) were categorized as receiving CB, BL, or no resuscitation (NR). …”
Get full text

CEST imaging combined with 1H-MRS reveal the neuroprotective effects of riluzole by improving neurotransmitter imbalances in Alzheimer’s disease mice by Yuanyu Shen, Xiaolei Zhang, Siqi Liu, Lijing Xin, Wentao Xuan, Caiyu Zhuang, Yue Chen, Beibei Chen, Xinhui Zheng, Renhua Wu, Yan Lin

“…However, whether riluzole can improve Glu and GABA homeostasis in AD brain and its related mechanism of action remain unknown. …”
Get full text

The Policy and Governance Observatory as a Facilitator of Smart and Evidence-based Governance by Atiye Yousefi, Mahdi Abdolhamid

“…In order to address this issue, the present article has done a comprehensive review of the most well-known observatories active in the field of policy making and public and topical governance around the world.…”
Get full text

Development of an Alternative Protocol to Study Muscle Fatigue by Daniela A. Alambarrio, Benjamin K. Morris, R. Benjamin Davis, Emily B. Grabarczyk, Kari K. Turner, John M. Gonzalez

“…The data indicated that EMS is a valuable tool for replicating ambulatory movement or physical activity, but super-contraction is not a means to accelerate postmortem muscle fatigue onset. …”
Get full text

Room temperature self-assembly and nonenzymatic electrochemical sensing performance of transition metal-embedded wheel-shaped tungstophosphates by Wen-Da Liu, Hao-Tian Zhu, Xue Zhang, Fang Su, Xiao-Jing Sang, Xiao-Lan Zhang, Lan-Cui Zhang

“…Compared with K28Li5[H7P8W48O184]·92H2O without 3d-TM and most reported POM electrode materials, the proposed 3d-TM-{P8W48} POMs exhibited higher stability and better activity during H2O2 detection. Composite films formed using 1–3 and chitosan (CS) on a glassy carbon electrode exhibited a high sensitivity (1.21 μA∙mmol∙L−1), low detection limit (0.02 mmol∙L−1), and rapid response time (2 s) for H2O2 detection. …”
Get full text

Relationships between paddock-level pasture mass and cow data derived from GPS and behavior-monitoring on-animal sensors in rotationally grazed dairy systems by S.J. Hendriks, M. Qasim, J.P. Edwards

“…Subsequently, all groups returned to baseline for 5 d (100%), followed by a switch, where the under-allocated groups were over-allocated, and vice versa, for the final 5 d. Each cow was fitted with 5 devices that were commercially available in New Zealand and measured rumination, eating, grazing, and lying time, and activity. …”
Get full text

Efficacy and Safety of Pramipexole Sustained Release versus Immediate Release Formulation for Nocturnal Symptoms in Chinese Patients with Advanced Parkinson’s Disease: A Pilot Stud... by Haiyan Zhou, Shuhua Li, Hongmei Yu, Shenggang Sun, Xinhua Wan, Xiaodong Zhu, Chun-Feng Liu, Ling Chen, Wei Xiang, Yaqing Sun, Haibo Chen, Shengdi Chen

“…SUSTAIN was an open-label, randomised, active-controlled parallel group exploratory pilot study (NCT03521635). …”
Get full text

Spatiotemporal variation in biomass abundance of different algal species in Lake Hulun using machine learning and Sentinel-3 images by Zhaojiang Yan, Chong Fang, Kaishan Song, Xiangyu Wang, Zhidan Wen, Yingxin Shang, Hui Tao, Yunfeng Lyu

“…Abstract Climate change and human activities affect the biomass of different algal and the succession of dominant species. …”
Get full text

Causes and determinants of infant mortality using verbal autopsy and social autopsy methods in a rural population of Odisha: a community-based matched case-control study by Amit Kumar Satapathy, Arvind Kumar Singh, Priyamadhaba Behera, Debkumar Pal, Abhisek Mishra

“…The cause of infant deaths should be assessed in both medical and social contexts.Objectives We aimed to determine the medical causes of infant mortality by verbal autopsy and its determinants in two rural blocks of the Khordha district of Odisha and assess the pathway of care and delay in seeking care for the illness preceding infant death using the three-delay model.Design We conducted this community-based matched case-control study to identify the medical causes of infant mortality using the verbal autopsy method along with the identification of delay and pathway of care related to infant deaths using a social autopsy method.Settings Two rural blocks of Odisha, India.Participants We enumerated 100 infant deaths by active surveillance and data triangulation from Accredited Social Health Activists, Auxiliary Nurse Midwives and block-level health information systems. …”
Get full text

Association between oxidative balance scores and peripheral artery disease in US adults: a cross-sectional study by Min Zhou, Min Zhou, Peng-Fei He, Peng-Fei He, Keren Zhang, Li-Juan Deng, Ning Wang, Gang Wang, Guang-Yao Yang, Shang Ju

“…Logistic regression analysis, adjusted for multiple potential confounders, revealed negative associations between lifestyle OBS (OR = 0.88; 95% CI: 0.79, 1.00), total OBS (OR = 0.97; 95% CI: 0.94, 0.99), and the likelihood of PAD (all p < 0.05). …”
Get full text

THE APPLICATION OF IOT (INTERNET OF THINGS) FOR SMART HOUSING ENVIRONMENTS AND INTEGRATED ECOSYSTEMS by Andi Hildayanti, M Sya'Rani Machrizzandi

“…Starting from smart cars that can walk alone to various destinations without a human driver, to smart home devices that can automatically remind the voice to do activities on schedule. All of this latest technology is part of the Internet of Things. …”
Get full text

Ancaman dan Faktor-Faktor yang Mendorong Swedia Bergabung dengan NATO pada Tahun 2024 by Aji Irvan Saputra, Indrawati Indrawati

“…Secondly, Sweden's geographical location and the rising activities in the Baltic Sea also influenced its decision. …”
Get full text

General immunologic reactivity of patients with COVID-19 and its relation to gene polymorphism, severity of clinical course of the disease and combination with comorbidities by M.O. Sokolenko, L.P. Sydorchuk, L.S. Sokolenko, A.A. Sokolenko

“…The aim of the study is to identify and evaluate the general immunological reactivity of patients with COVID-19 and its relationship with gene polymorphism, severity of the clinical course of the disease and combination with comorbidities. …”
Get full text

Access to context-specific lexical-semantic information during discourse tasks differentiates speakers with latent aphasia, mild cognitive impairment, and cognitively healthy adult... by Brielle C. Stark, Brielle C. Stark, Sarah Grace Dalton, Alyssa M. Lanzi, Alyssa M. Lanzi

“…This is problematic since many adults who have mild language deficits experience daily activity and participation limitations that are undetected and not managed. …”
Get full text

Efficacy of Aeromonas hydrophila formalin-killed cells and lipopolysaccharides vaccines in maternal immunity of tilapia broodstock and the offspring resistance by Rahma Mulyani, Sukenda Sukenda, Sri Nuryati

“…In the first experiment, the result showed that vaccinated broodstock and their offsprings had delivered a significant antibody level and lysozyme activity compared with the control.  The highest relative percent survival (RPS) of offspring resulted from the combination of  FKC and LPS vaccinated broodstock at 5, 10, and 15 days post-hatching at 85.00%, 75.23%, and 67.56%, respectively.  …”
Get full text

Evaluation method and application for in-situ stress in No. 8+9 coal seam, southern Shenfu block, northeastern margin of Ordos Basin by Jiawei WU, Wei TANG, Yanhe ZHU, Cunwu WANG, Yongjing TIAN, Jingyu ZI, Jianghao YANG, Xian SHI

Subjects: “…in-situ stress…”
Get full text

Analisa dan Perancangan Sistem Informasi Manajemen Validasi Data Pembangunan Fiber Optik by Akhmad Subhan, Wachyu Hari Haji

“…Abstract Management information systems become a necessity for a company or organization to assist operational activities, facilitate management in conducting supervision and increasing productivity. …”
Get full text

Cognitive Behavioural Therapy to Optimize Post-Operative Recovery (COPE): a randomized controlled feasibility trial in extremity fracture patients by Kyle Gouveia, Sheila Sprague, Jodi L. Gallant, Sarah MacRae, Gina Del Fabbro, Sofia Bzovsky, Paula McKay, Herman Johal, Jason W. Busse, on behalf of the COPE Investigators

“…The goals of our pilot study were to determine an acceptable rate of recruitment, the degree to which participants randomized to CBT were compliant with treatment, the site investigator’s ability to adhere to study protocol and data collection procedures, and our ability to achieve high follow-up rates. …”
Get full text

Rehabilitation using virtual gaming for Hospital and hOMe-Based training for the Upper limb post Stroke (RHOMBUS II): protocol of a feasibility randomised controlled trial by Cherry Kilbride, Tom Butcher, Meriel Norris, Nana Anokye, Alyson Warland, Karen Baker, Dimitrios A Athanasiou, Guillem Singla-Buxarrais, Jennifer Ryan, Francesca Gowing, Carole Pound, Victoria Stewart, Basaam Aweid, Arul Samiyappan

“…As such, time spent engaged in UL activity among subacute stroke survivors remains inadequate. …”
Get full text