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65801
Chondroitin Sulphate-Chitosan Based Nanogels Loaded with Naringenin-β-Cyclodextrin Complex as Potential Tool for the Treatment of Diabetic Retinopathy: A Formulation Study
Published 2025-01-01“…N3@NAR/β-CD capability to sustain in vitro NAR release, radical scavenging activity and in vitro biocompatibility were finally demonstrated.Conclusion: The physico-chemical properties of N3@NAR/β-CD were responsible for their cell uptake, suggesting their potential to target retinal endothelial cells. …”
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65802
The Influencers and the Adoption of New Products: Model for the Influencer Marketing
Published 2024-12-01“…Expertise follows, demonstrated by correct pronunciation of product names, experimenting with various usage methods, adequate knowledge of the product, and effectively showcasing its use. Interestingly, the study noted that in some cases, followers transform from being mere recipients to active participants, taking on the role of influencers themselves. …”
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65803
The Role of Autophagy in Copper-Induced Apoptosis and Developmental Neurotoxicity in SH-SY5Y Cells
Published 2025-01-01“…Compared with the 120 μM Cu<sup>2+</sup> exposure group alone, autophagy activator rapamycin pretreatment increased expression of Wnt and β-catenin nuclear translocation, decreased expression of LC3BII/LC3BI and p62, as well as upregulated expression of Bcl2 and downregulated expressions of caspase 3 and PARP. …”
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65804
Phase I trial of hydroxychloroquine to enhance palbociclib and letrozole efficacy in ER+/HER2− breast cancer
Published 2025-01-01“…Previously, we demonstrated that low doses of palbociclib activate autophagy, reversing initial G1 cell cycle arrest, while high concentrations induce off-target senescence. …”
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65805
Pengembangan Aplikasi Sistem Penilaian Praktik Pengalaman Lapangan pada Fakultas Ilmu Komputer Universitas Brawijaya Berbasis Web
Published 2021-10-01“…Abstract Field Experience Practice (FEP) is a pedagogy course that must be taken by all students of study program Information Technology Education (ITE) Department of Information Systems Faculty of Computer Science at Brawijaya University to apply professional educators in the field of Information and Communication Technology (ICT). …”
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65806
Evaluating Reaction Videos of Young People Watching Edutainment Media (MTV Shuga): Qualitative Observational Study
Published 2025-01-01“…They revealed how group composition, dynamics, settings, and storylines can maximize engagement with MTV Shuga to enhance HIV prevention education. The presence of parents and the camera may alter young people’s behavior, limiting the authenticity of their viewing experience. …”
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65807
Sobre fogones y semáforos: Percepciones y analogías de dos geografías desencontradas. El caso del volcán Callaqui en la geografía ancestral pehuenche de Alto Biobío
Published 2024-08-01“…However, the Pehuenches, ancestral inhabitants of the volcano's area of influence, have lived with it in an intrinsic way for generations, and they have associated a large part of their economic, social and cultural activities with the volcano itself, giving it a protective sense from their own perceptions regarding the mountainous massif. …”
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65808
Bibliometric analysis and review of food waste management via sustainable approaches
Published 2024-10-01“…Key developments in the field include the optimization of microbial consortia for enhanced degradation and conversion efficiency, as well as the engineering of enzymes to improve specificity and activity. These advancements have led to significant improvements in the efficiency and feasibility of converting food waste into high-value products. …”
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65809
FBR2 modulates ferroptosis via the SIRT3/p53 pathway to ameliorate pulmonary fibrosis
Published 2025-02-01“…FBR2 decreased collagen deposition in lung tissue, as shown by Masson’s staining and IHC detection of Col-I and α-SMA, confirming its anti-fibrotic effects. It also reduced iron and MDA levels in lung tissue, increased GSH-Px activity, improved mitochondrial morphology, and enhanced the expression of GPX4 and SLC7A11, indicating its ferroptosis-inhibitory capacity. …”
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65810
Legal regime of property registration: civil-legal aspect
Published 2024-12-01“…The need for legal certainty of the legal regime of inherited property from the moment of the testator’s death to the moment of its acceptance by the heir is substantiated. A regime of “legal protection” of property and property rights to it is proposed for such cases. …”
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65811
RBM47 promotes cell proliferation and immune evasion by upregulating PDIA6: a novel mechanism of pancreatic cancer progression
Published 2024-12-01“…RBM47-RNA immunoprecipitation (RIP) followed by PCR and dual luciferase reporter assay were used to detect whether RBM47 could interact with the PDIA6 mRNA and how RBM47 would regulate the transcriptional activity of PDIA6, respectively. Simultaneous overexpression of PDIA6 in RBM47 knockdown PC cells was conducted to clarify whether PDIA6 would mediated effects of RBM47. …”
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65812
Urinary NGAL and RBP Are Biomarkers of Normoalbuminuric Renal Insufficiency in Type 2 Diabetes Mellitus
Published 2019-01-01“…Levels of urinary neutrophil gelatinase-associated lipocalin (NGAL), retinol-binding protein (RBP), plasminogen activator inhibitor-1 (PAI-1), vascular cell adhesion molecule-1 (VCAM-1), and E-cadherin were detected, and their correlations with eGFR, plasma TNF-α, IL-6, endothelin-1 (ET-1), and 8-hydroxydeoxyguanosine (8-OHdG) were assessed. …”
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65813
Development of the Big Ten Academic Alliance Collaborative for Women in Medicine and Biomedical Science: “We Built the Airplane While Flying It”
Published 2025-01-01“…Opportunities for additional, targeted career development activities are imperative in developing and retaining women+ faculty. …”
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65814
Evaluation of Machine Learning Algorithms for Classification of Visual Stimulation-Induced EEG Signals in 2D and 3D VR Videos
Published 2025-01-01“…These results expand the application of feature-based machine learning methods in EEG studies and provide a foundation for future research into the brain cortical activity of VR experiences, supporting the broader use of machine learning in EEG-based analyses.…”
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65815
JAUNOSIOS KARTOS KATALIKŲ INTELEKTUALŲ POŽIŪRIS Į FAŠIZMĄ IR NACIONALSOCIALIZMĄ TARPUKARIO LIETUVOJE
Published 2001-01-01“…So, the fascists interpreted corporations as a means to strengthen the power of the state and to extend its influence and intellectual Catholic youth considered them a way to reduce an omnipotence of the state pursuing its decentralization. …”
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65816
Transcription factors MhyFIL1 and MhyFIL3 <i>(Monotropa hypopitys)</i> determine the asymmetric development of above-ground lateral organs in plants
Published 2019-07-01“…It is believed that the complete mycoheterotroph pinesap Monotropa hypopitys adaptively evolved from a photosynthetic mycorrhizal ancestor, which had lost its photosynthetic apparatus and vegetative organs (stem and leaves). …”
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65817
Pelvic Drop Changes due to Proximal Muscle Strengthening Depend on Foot-Ankle Varus Alignment
Published 2019-01-01“…In addition, this study evaluated the effects of hip and trunk muscle strengthening on hip passive and active properties, in the same subgroups. Methods. …”
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65818
Dietary rosemary oil with/without zymogen forte improves water quality, growth hormones, immune-physiological response, stress resilience, and health status of Chelon ramada grown...
Published 2025-01-01“…Furthermore, there were increases in plasma heat shock proteins HSP70 and HSP90, as well as enhanced antioxidant activity. These gains were associated with healthier liver and intestines. …”
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65819
Influence of Extra-Articular Augmentation on Clinical Outcomes and Survival in Patients Undergoing Anterior Cruciate Ligament Reconstruction: A Pseudorandomized Study
Published 2025-01-01“…Our objective is to compare the results of these techniques, with a primary focus on assessing knee stability and graft survival, to provide evidence for optimizing surgical approaches, particularly for athletes and physically active individuals. <i>Materials and Methods</i>: An observational study using paired score matching as a method of pseudo-randomization was conducted. …”
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65820
Industry of employment and occupational class in relation to cardiovascular health by race/ethnicity, sex/gender, age and income among adults in the USA: a cross-sectional study
Published 2024-04-01“…Adjusting for sociodemographic, clinical factors, and health behaviour confounders, we used Poisson regression with robust variance to estimate prevalence ratios (PRs) and 95% CIs of mICVH overall and by race/ethnicity and performed Wald tests for interaction.Results Latinx (53%) and NH-Black (37%) adults were more likely than NH-White adults (29%) to report labourer positions and had the lowest prevalence of mICVH (5.2% (Latinx) and 3.9% (NH-Black)). …”
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