A STUDY OF THE INFLUENCE OF EXTRACELLULAR VESICLES ON THE MORPHOFUNCTIONAL STATE OF THE ENDOMETRIUM IN VITRO by Оксана Александровна Мелкозерова, Ирина Викторовна Крутинь, Александра Юрьевна Храмцова, Мария Валерьевна Улитко, Алсу Фармутовна Мустафина

“…Of great importance in the implantation process is the receptivity of the endometrium, that is, its ability to ensure the necessary stages of implantation. …”
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Rusførebygging i skulen som diskursivt forma pedagogisk-politisk fenomen. Eit teoretisk-empirisk bidrag til omgrepsutvikling by Øyvind Wiik Halvorsen, Liv Eide, Olin Blaalid Oldeide

“…For det fyrste vil artikkelen utmynte eit diskursorientert teoretisk rammeverk for å analysere rusførebygging i skulen som eit pedagogisk-politisk fenomen. …”
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Prevalence of communicable, non-communicable diseases, disabilities and related risk factors in Khyber Pakhtunkhwa Pakistan: Findings from the Khyber Pakhtunkhwa Integrated Populat... by Ziaul Haq, Saima Afaq, Muhammad Ibrahim, Zala, Muhammad Asim

“…Observations were recorded on demographics, quality of life, physical activity, BMI, disabilities, CDs and NCDs.<h4>Results</h4>Among all NCDs, hypertension has the highest prevalence (29.2%), showing a significant difference between females (32.7%) and males (25.0%). …”
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New Insights into the Role of Inflammatory Pathways and Immune Cell Infiltration in Sleep Deprivation-Induced Atrial Fibrillation: An Integrated Bioinformatics and Experimental Stu... by Liang J, Tang B, Shen J, Rejiepu M, Guo Y, Wang X, Shao S, Guo F, Wang Q, Zhang L

“…Furthermore, we utilized immunofluorescence and Western blot techniques to evaluate YBX1 expression and its role in activating NLRP3 inflammasomes in a rat model induced by SD.Results: A total of 540 common DEGs were precisely identified between the AF and SD data collections. …”
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Application of Computer Simulation in Exploring the Effects of <italic>Achyranthis Bidentatae Radix</italic> on Simultaneously Treating Wei Syndrome and Bi Syndrome of Osteoarthrit... by Chunsong ZHENG, Hongzhi YE, Jinxia YE, Changlong FU

“…Based on the platforms of quantitative structure-activity relationship and principal component analysis, the distributions of the above datasets were analyzed in the chemical space.②Matrix metalloproteinase-1 (MMP-1), matrix metalloproteinase-3 (MMP-3), and transforming growth factor beta-1 (TGF-β1) were chosen as the targets of treating Wei Syndrome of OA, while interleukine-1 beta (IL-1β), interleukine-6 (IL-6), tumor necrosis factor-alpha (TNF-α) were chosen as the targets of treating Bi syndrome of OA. …”
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Analysis of an intergenerational service-learning experience based on physical exercise in a community setting: a mixed-method study by Beatriz Alonso-Cortés Fradejas, Raquel Lafuente-Ureta, Sandra Calvo, Sandra Calvo, Mario Fernández-Gorgojo, Jose Lesmes Poveda-López, Carolina Jiménez-Sánchez, Carolina Jiménez-Sánchez

“…IntroductionPhysical activity offers numerous benefits that improve psychological well-being, reduce dependency, and foster intergenerational relationships. …”
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Intermittent auscultation fetal monitoring during labour: A systematic scoping review to identify methods, effects, and accuracy. by Ellen Blix, Robyn Maude, Elisabeth Hals, Sezer Kisa, Elisabeth Karlsen, Ellen Aagaard Nohr, Ank de Jonge, Helena Lindgren, Soo Downe, Liv Merete Reinar, Maralyn Foureur, Aase Serine Devold Pay, Anne Kaasen

“…<h4>Background</h4>Intermittent auscultation (IA) is the technique of listening to and counting the fetal heart rate (FHR) for short periods during active labour and continuous cardiotocography (CTC) implies FHR monitoring for longer periods. …”
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Geochemical signatures and nanomechanical properties of echinoid tests from nearshore habitats of Florida: environmental and physiological controls on echinoid biomineralization by Przemysław Gorzelak, Luis Torres Jr., Dorota Kołbuk, Tobias B. Grun, Michał Kowalewski

“…The mechanisms that regulate minor and trace element biomineralization in the echinoid skeleton can be primarily controlled biologically (i.e., by the organism and its vital effects) or by extrinsic environmental factors. …”
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Soil-transmitted helminthiasis among adolescents in Anaocha Local Government Area, Anambra State, Nigeria: Insights and recommendations for effective control. by Ogechukwu B Aribodor, Eunice C Jacob, Nwadiuto O Azugo, Uche C Ngenegbo, Ifeanyi Obika, Emmanuel M Obikwelu, Obiageli J Nebe

“…Class (grade level) (OR = 1.75, 95% CI: 1.25-2.45, p = 0.003), knowledge and transmission of STH infection (OR = 0.60, 95% CI: 0.42-0.86, p = 0.008), parental occupation (OR = 1.90, 95% CI: 1.35-2.67, p < 0.001), parents' literacy level (OR = 0.68, 95% CI: 0.48-0.96, p = 0.027), and the type of toilet (OR = 2.15, 95% CI: 1.54-3.00, p < 0.001) were all significantly correlated with STH infection. …”
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RamA upregulates the ATP-binding cassette transporter mlaFEDCB to mediate resistance to tetracycline-class antibiotics and the stability of membranes in Klebsiella pneumoniae by Xiaoyu Zhao, Yixin Zhang, Mohan Ju, Yang Yang, Haoqi Liu, Xiaohua Qin, Qingqing Xu, Min Hao

“…Furthermore, an electrophoretic mobility shift assay showed that RamA could bind to the promoter region of mlaEFDCB operon, which confirmed RamA is an activator of mlaEFDCB operon. The mlaEFDCB operon could mildly mediate resistance to the tetracycline family of antibiotics under RamA regulation. …”
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Effect of Task Oriented Training on Gross Motor Dysfunction for Children with Cerebral Palsy： A Meta-Analysis by LI Yang, CHEN Ying, ZHU Xiangyu, SHI Jiehong, FENG Yuan, WU Wenlei, FU Ruochen

“…Meta-analysis results showed that, compared with the control group, the GMFM scale standing score in the experimental group was higher [<italic>SMD</italic>=0.78, 95% <italic>CI</italic> (0.59, 0.98), <italic>P</italic>&lt;0.000 01], walking, running and jumping scores was higher [<italic>SMD</italic>=4.05, 95% <italic>CI</italic> (2.06, 6.05), <italic>P</italic>&lt;0.000 01], GMFM scale overall score was higher [<italic>SMD</italic>=10.23, 95% <italic>CI</italic> (7.00, 13.46), <italic>P</italic>&lt;0.000 01], PEDI score was higher [<italic>SMD</italic>=6.87, 95% <italic>CI</italic> (4.19, 9.54), <italic>P</italic>&lt;0.000 01], TUG test time was shorter [<italic>SMD</italic>=-3.17, 95% <italic>CI</italic> (-4.84, -1.49), <italic>P</italic>=0.000 2], and BBS score was higher [<italic>SMD</italic>=5.26, 95% <italic>CI</italic> (4.05, 6.46), <italic>P</italic>&lt;0.000 01].ConclusionTask oriented training can effectively improve the gross motor function (such as walking, running, jumping, etc.) of children with cerebral palsy, shorten the TUG test time, and improve their balance function and activities of daily living.…”
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The search for a blood-based biomarker for Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome (ME/CFS): from biochemistry to electrophysiology by Krista S. P. Clarke, Caroline C. Kingdon, Michael Pycraft Hughes, Eliana Mattos Lacerda, Rebecca Lewis, Emily J. Kruchek, Robert A. Dorey, Fatima H. Labeed

“…One in four individuals are bed-bound for long periods of time, others have difficulties maintaining a job/attending school, incurring individual income losses of thousands, while few participate in social activities. Main body Recent studies have reported promising quantifiable differences in the biochemical and electrophysiological properties of blood cells, which separate ME/CFS and non-ME/CFS participants with high sensitivities and specificities—demonstrating potential development of an accessible and relatively non-invasive diagnostic biomarker. …”
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Synergistic removal of organic and nutrients from landfill leachate using photobioreactor-cultivated microalgae-bacteria consortium by N. Emalya, Y. Yunardi, E. Munawar, S. Suhendrayatna, T. Tarmizi

“…BACKGROUND AND OBJECTIVES: The utilization of stabilization pond system for landfill leachate treatment is hindered by its requirement for expansive land areas and extended retention periods. …”
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Adopsi E-Commerce oleh Konsumen Milenial Pada Produk UMKM Di Kota Subang Menggunakan Model UTAUT In Consumer Contex by Rian Piarna, Ferdi Fathurohman

“…These results can be a reference for SMEs to develop marketing by using social media because millennial consumers have the facility to access the internet in their activities and are easily influenced by their social environment. …”
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Blockades of effector T cell senescence and exhaustion synergistically enhance antitumor immunity and immunotherapy by Xia Liu, Emily Shaw, Fusheng Si, Guangyong Peng, Yan Tao, Feiya Ma, David Bagley, Yuanqin Zhang

“…Induction of ataxia-telangiectasia mutated protein (ATM)-associated DNA damage is the cause for T cell senescence induced by both mouse tumor cells and Treg cells, which is also regulated by mitogen-activated protein kinase (MAPK) signaling. Furthermore, blockages of ATM-associated DNA damage and/or MAPK signaling pathways in T cells can prevent T cell senescence mediated by tumor cells and Treg cells in vitro and enhance antitumor immunity and immunotherapy in vivo in adoptive transfer T cell therapy melanoma models. …”
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Time to recovery of neonatal sepsis and its predictors in public hospitals of North Shoa Zone, Central Ethiopia by Befekadu Tesfaye Oyato, Teshome Ketema Sime, Tirunesh Debele, Husen Zakir Abasimel, Fikadu Tolesa Alemu, Samuel Boja Asfaw, Wuletaw Tadesse Mekonnin, Hana Israel Gesisa, Elleni Tesfaye Kebede

“…The adjusted hazard ratio (AHR) with its corresponding 95% confidence interval (CI) was employed. …”
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MTMR6 downregulation contributes to cisplatin resistance in oral squamous cell carcinoma by Kah Young Lee, Su Young Oh, Heon-Jin Lee, Tae-Geon Kwon, Jin-Wook Kim, Chang-Geol Shin, Su-Hyung Hong, So-Young Choi

“…Methods MTMR6 expression was compared between UMSCC1 and cisplatin-resistant UM-Cis cells. Gain- and loss-of-function experiments involving MTMR6 was performed to evaluate its impact on cisplatin resistance. …”
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Arctiin Protects Chondrocytes from Interleukin-1β-Induced Inflammation and Apoptosis by RNA Sequence In vivo and In vitro by Yong-Jia Song, Jia-Min Bao, Zeng-Qiao Zhang, Yun-Xiang Hai, Hao-Nan Wen, Tian-Jun Zhai, Wei Feng, Min Song

“…Furthermore, Safranin-O fast green staining and immunohistochemistry staining were performed on slices of the mice knee joint to evaluate the OA Research Society International score, alterations in the cartilage matrix, and levels of apoptosis-related proteins at sites of knee cartilage damage in an arthritis model induced by monosodium iodoacetate (MIA) and physical activity. …”
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Prospects for the use of a <i>Bacillus subtilis</i> metabolites-based feed additive in dairy farming by S. V. Malkov, A. S. Krasnoperov, A. P. Poryvaeva, O. Yu. Oparina, A. I. Belousov, A. N. Brilliant

“…The feed additive impact on main body systems of the tested cows (n = 30), milk production parameters, growth rate of the calves (n = 18) born to the said cows were examined. …”
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Integrative RNA, miRNA, and 16S rRNA sequencing reveals immune-related regulation network for glycinin-induced enteritis in hybrid yellow catfish, Pelteobagrus fulvidraco ♀ × Pelte... by Linyuan Yi, Aijie Mo, Huijun Yang, Yifan Yang, Qian Xu, Yongchao Yuan, Yongchao Yuan, Yongchao Yuan

“…Glycinin causes growth retardation and intestinal damage in hybrid yellow catfish (Pelteobagrus fulvidraco ♀ × Pelteobagrus vachelli ♂), but its immune mechanisms are largely unknown. In the current study, five experimental diets containing 0% (CK), 1.74% (G2), 3.57% (G4), 5.45% (G6), and 7.27% (G8) immunological activity of glycinin were fed to juvenile hybrid yellow catfish to reveal the mechanism of the intestinal immune response to glycinin through RNA and microRNA (miRNA) sequencing and to explore the interrelation between immune molecules and intestinal microbiota. …”
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