Targeted detection of endogenous LINE-1 proteins and ORF2p interactions by Mathias I. Nielsen, Justina C. Wolters, Omar G. Rosas Bringas, Hua Jiang, Luciano H. Di Stefano, Mehrnoosh Oghbaie, Samira Hozeifi, Mats J. Nitert, Alienke van Pijkeren, Marieke Smit, Lars ter Morsche, Apostolos Mourtzinos, Vikram Deshpande, Martin S. Taylor, Brian T. Chait, John LaCava

“…The ability to assay ORF2p directly and quantitatively will improve our understanding of the developmental and diseased cell states where L1 expression and its activity naturally occur. The ability to simultaneously assay endogenous L1 ORF1p and ORF2p is an important step forward for L1 analytical biochemistry. …”
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Adherence to four healthy lifestyle factors and their influencing factors among residents aged 35 – 75 in South China: a cross-sectional survey by Wenyan HE, Xingyi ZHANG, Chunqi WANG, Xueke BAI, Yang YANG, Wei XU, Lijuan SONG, Yan ZHANG, Hao YANG, Xi LI, Jianlan CUI

“…ConclusionsThe adherence rates to non-smoking, no or moderate alcohol consumption, adequate physical activity, and a healthy diet were low among residents aged 35 – 75 years in South China. …”
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Path model explaining the association between fear of falling and health-related quality of life in (pre-)frail older adults by Tjard Sattler, Sophie Gottschalk, Hans-Helmut König, Tobias Braun, Gisela Büchele, Michael Denkinger, Tim Fleiner, Corinna Nerz, Kilian Rapp, Martina Schäufele, Christian Werner, Judith Dams

“…Results The model demonstrated good fit to the data and the remaining direct effect of FoF on HrQoL was small (β=-0.05). …”
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In vitro anticancer effects of frankincense and its nanoemulsions for enhanced cancer cell targeting by Rayya A. Al-Balushi, Aiswarya Chaudhuri, Raghuram Kandimalla, Ashanul Haque, Khalaf M. Alenezi, Mohd. Saeed, Mohammad Changez, Thuraya Al Harthy, Mohammed Al Hinaai, Samra Siddiqui, Ashish Kumar Agrawal, Farrukh Aqil, Farrukh Aqil

“…IntroductionFrankincense has demonstrated promising in vitro anticancer activity. However, its conventional delivery methods face significant challenges due to limited oral bioavailability. …”
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Physiological impact of Trichoderma viride agents on the quality and production of melon that is grown on soils continuously cropped to melon by Jingyi Liu, Hua Lian, Jingwei Dou, Jingjing Li, Guangliang Zhu, Jiatong Wang, Guangshu Ma, Mei Li

“…The results showed that different amounts of T. viride agents could improve physiological and biochemical indices of melon leaves during the fruiting stage; the treatment of 6.4 × 105 CFU/g was the most effective; chlorophyll content, nitrate nitrogen content, sucrose content, reducing sugar content, free proline content, nitrate reductase (NR) activity, peroxidase (POD) activity, and superoxide dismutase (SOD) activity of melon leaves increased at 30 days after melon pollination. …”
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Evidence adaptation and tailored implementation of family bereavement support in specialised palliative care: A multi-method study by Myrta Kohler, Qëndresa Thaqi, Silke Kuske, Torsten Schwalbach, Marco Riguzzi, Rahel Naef

“…Evidence-based recommendations for bereavement support are often not well implemented in palliative care services due to multiple system barriers and lack of contextual fit. To close this know-do gap, we undertook an implementation science research project. …”
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Cellular senescence induced by cholesterol accumulation is mediated by lysosomal ABCA1 in APOE4 and AD by Shaowei Wang, Boyang Li, Jie Li, Zhiheng Cai, Cristelle Hugo, Yi Sun, Lu Qian, Julia TCW, Helena C. Chui, Dante Dikeman, Isaac Asante, Stan G. Louie, David A. Bennett, Zoe Arvanitakis, Alan T. Remaley, Bilal E. Kerman, Hussein N. Yassine

“…Cholesterol accumulation is known to drive cellular senescence; however, its underlying mechanisms are not fully understood. …”
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Perancangan Sistem Informasi Basis Data IKM Binaan Pada Dinas Perindustrian dan Perdagangan Provinsi Jawa Barat by Iman Sudirman, Atya Nur Aisha, Joe Monang, Taufan Fadhilah Iskandar

“…The results showed that all activities proposed for each type of user have been successfully performed by the system as required. …”
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Targeting aldose reductase using natural African compounds as promising agents for managing diabetic complications by Miriam E. L. Gakpey, Shadrack A. Aidoo, Toheeb A. Jumah, George Hanson, Siyabonga Msipa, Florence N. Mbaoji, Omonijo Bukola, Palesa C. Tjale, Mamadou Sangare, Hedia Tebourbi, Olaitan I. Awe

“…Prediction of biological activity highlighted Zinc000095485961 and 1,6-di-o-p-hydroxybenzoyl-beta-d-glucopyranoside as having significant inhibitory activity against aldose reductase. …”
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Semen quality and fertility effectiveness of cloned buffalo (Bubalus bubalis) bulls by Manoj Kumar Singh, Smiriti Gupta, Kanika Gandhi, S.S. Lathwal, Naresh L. Selokar

“…These calves are physiologically normal, growing well and healthy. …”
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CD4 T cell depletion increases memory differentiation of endogenous and CAR T cells and enhances the efficacy of Super2 and IL-33-armored CAR T cells against solid tumors by Chrystal Paulos, Mary Jo Turk, Megen C Wittling, Yina H Huang, Asmaa O Mohamed, David Tyler Boone, Shannon L Ferry, Melanie C Peck, Alicia M Santos, Haille E Soderholm

“…In contrast, S233-armored CAR T cells exhibited an activated effector phenotype and differentiated inefficiently into CAR effector and central memory T cells. …”
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Gender Analysis, Milk Value Chain, Kabale Uganda. Kabale: Kabale University. by Tugume, Samuel

“…The specific objectives of the study involved ascertaining the activities involved by the male and female genders in the milk value chain, who controls resources and decision-making, and the challenges faced by the male and female genders in the milk value chain in the study area. …”
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MECHANISMS AND CLINICAL PERSPECTIVES OF ALLERGEN-SPECIFIC IMMUNOTHERAPY by Leila Akhvlediani, Marina Izmailovich, Meruyert Gazaliyeva, Anna Skvortsova, Kanan Tanriverdiev

“…Results and Discussion: ASIT promotes immunological tolerance through mechanisms such as suppression of Th2 activity, increased IgG4 production, and reduced effector cell activation. …”
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Influence of boriding treatment on the mechanical properties of Monel 400 by Christian Pacheco, Jefferson Luiz Jeronimo, Anael Preman Krelling, Cesar Edil da Costa, Júlio Cesar Giubilei Milan

“…X-ray Diffraction (XRD) was used to determine the phases present. The boron activation energy, determined through kinetic diffusion theory, was found to be 157.2 kJ mol−1. …”
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Dietary phytochemical index and the risk of gallstone disease: a case-control study by Mohammad Abdulmohsin Jebur, Ghufran Lutfi Ismaeel, Haitham Mukhklif Salim, Ammar Hussein Ahmed, Israa Habeeb Naser

“…In the final adjusted model, which accounted for additional confounders such as physical activity, BMI, smoking, socioeconomic status (SES), and dietary intake of energy, participants in the highest tertile of total PI still had a lower risk of gallston compared to those in the lowest tertile (OR and 95% CI = 0.51 (0.28–0.90), p for trend = 0.031. …”
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Levels of IL-6 and IL-1β in Umbilical Cord Blood in Relation to Mode of Birth by Ebru Aslan Patlakoğlu, Sündüz Özlem ALTINKAYA, Mustafa Uğur, Cuma Taşın, Nezaket Kadıoğlu

“…IL-6 and IL-1β levels were measured with commercial kits. All of the subjects had uncomplicated term singleton pregnancies. …”
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Corallocarpus glomeruliflorus: Pharmacological potential revealed by phytochemical and in silico investigations by Fatima Saleh Naji Bin-Asal, Adel A.M. Saeed, Abdul-Rahman Alawi Bin Yahia

“…The extract demonstrated superior antimicrobial activity against Pseudomonas aeruginosa compared to previous studies, with a zone of inhibition of 16.7 ± 1.53 mm at 200 mg/mL concentration. …”
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Effect of <i>Chlorella</i> on hematological parameters and nutrient bioavailability in the diet of rhesus monkeys (<i>Macaca mulatta</i>) by N. V. Gaponov, Al. V. Panchenko, An. V. Panchenko, Yu. P. Chuguev

“…Chlorella shows a wide spectrum of biological activity, in particular, it exhibits a pronounced antioxidant activity and demonstrates anti-inflammatory, antitumor and antiviral properties. …”
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Gene therapy by hepatocyte growth factor results in regression of experimental liver fibrosis by N. A. Dzhoyashvili, N. I. Kalinina, I. B. Beloglazova, Z. I. Tsokolayeva, P. I. Makarevich, Yu. L. Perov, Ye. V. Parfenova, V. A. Tkachuk

“…A blood was extracted for assessment of liver enzymes activity (AST and ALT). Human HGF was injected into liver tissue by hydroporation method. …”
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Tracing the trajectories of energy intensity, environmental tax revenues, and environmental neutrality in major European economies by Fayyaz Ahmad, Nabila Abid, Junaid Aftab, Aamir Javed

“…Notably, higher energy intensity is positively linked to increased environmental management activities, reflecting a commitment to address abatement goals and indicating funds are allocated toward pollution mitigation, aligning with Europe's emphasis on sustainability. …”
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