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64681
Associations between contextual and compositional characteristics of early childcare facilities with health, health behaviours and well-being among young children aged 0 to 6 years...
Published 2020-09-01“…After the completion of the title/abstract screening, full texts of the remaining articles will be screened following the same procedure. …”
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64682
Efficacy, efficiency and safety of a cardiac telerehabilitation programme using wearable sensors in patients with coronary heart disease: the TELEWEAR-CR study protocol
Published 2022-06-01“…The primary outcomes will be the assessment of cardiorespiratory fitness, expressed as peak oxygen uptake assessed by the CPET test and the 6 min walk test. …”
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64683
Prevalence and prognostic value of ventricular conduction delay in heart failure with preserved ejection fraction
Published 2025-04-01“…Only 4 % had a QRS area ≥69µVs, indicating delayed lateral wall activation. After a median of 3 years follow-up, 30 % of the patients had an adverse outcome. …”
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64684
BPZ inhibits early mouse embryonic development by disrupting maternal-to-zygotic transition and mitochondrial function
Published 2025-01-01“…The use of Bisphenol A (BPA) has been widely restricted due to its adverse health effects. Bisphenol Z (BPZ) is used as an alternative to BPA, and humans are widely exposed to BPZ through various routes. …”
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64685
The ArcB kinase sensor participates in the phagocyte-mediated stress response in Salmonella Typhimurium
Published 2025-02-01“…The ArcA transcription factor activates genes related to metabolism, membrane permeability, and virulence, and its presence is required for pathogenicity in Salmonella Typhimurium, which can be phosphorylated independently of its cognate sensor, ArcB. …”
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64686
Antioxidant Potential, Subacute Toxicity, and Beneficiary Effects of Methanolic Extract of Pomelo (Citrus grandis L. Osbeck) in Long Evan Rats
Published 2019-01-01“…Pomelo extract contained high concentrations of polyphenols, flavonoids, and ascorbic acid while exhibiting high 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity and ferric reducing antioxidant power values. …”
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64687
Kaempferol protects against high-salt-induced hypertension and vascular endothelial injury by inhibiting ferroptosis through the ATF4/ACSL4 pathway
Published 2025-02-01“…To date, no specific treatments have been developed for high-salt-induced hypertensive vascular damage, emphasizing the need to elucidate its underlying molecular mechanisms for therapeutic innovation. …”
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64688
SEGS-1 episomes generated during cassava mosaic disease enhance disease severity
Published 2025-01-01“…The functional regions of SEGS-1 were mapped using TME3 to sequences flanking the episome junction, but the junction itself was not required for activity. All cassava cultivars have SEGS-1 sequences in their genomes that have the potential to negatively impact the development of stable CMD resistance by cassava breeding programs.…”
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64689
Exploring the capacity of microorganism treatment for fermentation and glycosidic aroma bioconversion from rose oil distillation wastewater
Published 2024-12-01“…The process of water-steam distillation is commonly used to extract rose oil, with an extraction efficiency of ~ 0.03–0.05% for active components. However, a significant amount of waste is generated during this process, with a large portion of the distillate being composed of water. …”
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64690
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64691
Investigating the triple-frequency ultrasound-assisted fermented rice lees: Impact on physicochemical, structural, morphological, and metabolic properties
Published 2025-01-01“…Additionally, FTIR spectral analyses demonstrated that TFUT-assisted fermented RL exhibited a greater degree of flexibility and mobility in its secondary structures compared to RL (control). …”
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64692
The modern options of chronic hepatitis C antiviral therapy with daclatasvir: results of named patient program
Published 2018-08-01“…To analyze the efficacy of PTV for chronic hepatitis C within the named patient program of expanded access to daclatasvir. …”
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64693
Discovery of the microbiota-gut-brain axis mechanisms of acupuncture for amnestic mild cognitive impairment based on multi-omics analyses: A pilot study
Published 2025-03-01“…Conclusions: Our data imply that acupuncture ameliorates overall cognitive function, along with changes in brain activity, gut microbiota, and serum metabolites, providing preliminary evidence of the mechanisms acting through the MGB axis underlying the effects of acupuncture on aMCI.…”
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64694
Variability and Source Characterization of Regional PM of Two Urban Areas Dominated by Biomass Burning and Anthropogenic Emission
Published 2022-04-01“…Abstract Identifying the sources and formation pathways of particulate matter (PM) and its components is important to determine the impact of atmospheric aerosols on human health and the warming of the global atmosphere. …”
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64695
Effects of Long-Term Serum Starvation on Autophagy, Metabolism, and Differentiation of Porcine Skeletal Muscle Satellite Cells
Published 2024-12-01“…The expression of proteins associated with myogenic and adipogenic differentiation (MHC, MyoD1, peroxisome proliferator-activated receptor <i>γ</i>, and lipoprotein lipase) as well as lipid content were also determined to investigate the effects of long-term serum starvation on SMSC differentiation. …”
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64696
Hei-Gu-Teng Zhuifenghuoluo Granule Modulates IL-12 Signal Pathway to Inhibit the Inflammatory Response in Rheumatoid Arthritis
Published 2018-01-01“…Furthermore, HGT effectively inhibited the activation of IL-12R and STAT4 on IL-12 signaling pathway. …”
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64697
3D nanocomposites of β-TCP-H3BO3-Cu with improved mechanical and biological performances for bone regeneration applications
Published 2025-01-01“…Abstract Recently, 3-D porous architecture of the composites play a key role in cell proliferation, bone regeneration, and anticancer activities. The osteoinductive and osteoconductive properties of β-TCP allow for the complete repair of numerous bone defects. …”
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64698
Targeting of the HER2/HER3 signaling axis overcomes ligand‐mediated resistance to trastuzumab in HER2‐positive breast cancer
Published 2019-03-01“…Abstract HER2‐targeted therapy, especially the anti‐HER2 antibody trastuzumab, is standard for HER2‐positive breast cancer; however, its efficacy is limited in a subpopulation of patients. …”
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64699
Deficiency of the mitochondrial transporter SLC25A47 minimally impacts hepatic lipid metabolism in fasted and diet-induced obese mice
Published 2025-02-01“…Objective: The peroxisome proliferator-activated receptor-alpha (PPARα) plays a central role in lipid metabolism in the liver by stimulating the expression of hundreds of genes. …”
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64700
Understanding the mechanisms of hypoxia-induced tissue damage in fish: The role of GasderminEa/b in Larimichthys crocea
Published 2025-01-01“…Taken together, these findings demonstrate that hypoxia stress could activate LcGSDMEa/b and induce pyroptosis in the liver of large yellow croakers, thereby contributing to tissue damage. …”
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