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6441
Adapting the Home
Published 2012-11-01“…This revised 4-page fact sheet discusses AARP’s 10 basic ideas to increase home safety, how to individualize for each person or activity, how to apply universal design to make homes safer, and assistive devices. …”
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6442
Mycorrhizae: Implications for Environmental Remediation and Resource Conservation
Published 2008-04-01“…Al-Agely, describes the symbiotic relationships between plant roots and fungi and how the resulting rhizosphere activity can lead to transformation and removal of polluting compounds from the soil, reduce the need for fertilizer in commercial nurseries, and improve soil structure and health. …”
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6443
Mediator kinase inhibition suppresses hyperactive interferon signaling in Down syndrome
Published 2025-02-01“…Using sibling-matched cell lines with/without T21, we investigated Mediator kinase function in the context of hyperactive IFN in DS over a 75 min to 24 hr timeframe. Activation of IFN-response genes was suppressed in cells treated with the CDK8/CDK19 inhibitor cortistatin A (CA), via rapid suppression of IFN-responsive transcription factor (TF) activity. …”
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6444
Permafrost pore structure and its influence on microbial diversity: Insights from X-ray computed tomography
Published 2025-02-01“…Although once thought to be devoid of microbial activity, more recent advances demonstrate permafrost is an active ecosystem albeit less than most unfrozen soil. …”
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6445
The AMD-associated genetic polymorphism CFH Y402H confers vulnerability to Hydroquinone-induced stress in iPSC-RPE cells
Published 2025-02-01“…One of the main genetic risks includes the Y402H polymorphism in complement Factor H (FH), an inhibitor of complement system activation. There has been, and continues to be, much discussion around the functional consequences of this Y402H polymorphism, whether the soluble FH protein confers its risk association, or if the cells expressing the protein themselves are affected by the genetic alteration. …”
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6446
Targeting sphingosine 1-phosphate receptor 3 inhibits T-cell exhaustion and regulates recruitment of proinflammatory macrophages to improve antitumor efficacy of CAR-T cells agains...
Published 2023-08-01“…Mechanistically, the S1PR3 antagonist improved CAR-T cell activation, regulated the central memory phenotype, and reduced CAR-T cell exhaustion in vitro. …”
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6447
Parasitic infection prevalence in tuberculosis patients and their household contacts in the Littoral Region of Cameroon
Published 2025-02-01“…TB patients and household contacts living in urban areas had lower odds of being associated with helminth infections (AOR 0.2, 95 % CI: 0.10–0.40; p ˂ 0.0001 and AOR 0.11, 95 % CI: 0.04–0.27; p ˂ 0.0001 respectively) as compared to those residing in rural areas. …”
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6448
Baccaurea ramiflora fruit peel powder supplementation prevented inflammatory cell infiltration, oxidative stress, and fibrosis in carbon tetrachloride (CCl4) administered ovariecto...
Published 2025-02-01“…The catalase and superoxide dismutase activities were also restored in the plasma of CCl4-administered rats. …”
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6449
Growth, fat metabolism and hepatic health in largemouth bass fed varying fat-level diets
Published 2025-03-01“…Serum biochemical indexes and serum alanine aminotransferase (ALT) activity, liver glutathione peroxidase (GSH-Px) and catalase (CAT) activities were increased significantly with rising dietary fat levels (P<0.05), serum aspartate transaminase (AST) and liver superoxide dismutase (SOD) activities had no statistical differences (P>0.05). …”
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6450
Jaringan Komunitas Berbasis Similaritas Topik Bahasan dan Emosi untuk Mengidentifikasi Perilaku Pengguna Twitter
Published 2023-02-01“…Based on the analysis of 121 active users, before the COVID-19 period had 98 representative users, who were dominated by 33% of community behavior related to personal activities with happy emotions. …”
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6451
Residents as learning facilitators inside and outside of interprofessional education: a faculty development program in postgraduate pediatric training
Published 2025-02-01“…When students experience IPE activities during their undergraduate training, they are often guided by trained learning facilitators. …”
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6452
Model Sistem Berbasis Pengetahuan untuk Rekomendasi Aktivitas Pensiun
Published 2021-10-01“…The use of these two methods aims to provide better results in providing recommendations for retirement activities. The results of this study after testing the User Acceptance Test (UAT) of 30 respondents on the system resulted in the conclusion that this system helps provide recommendations of activities for retirement preparation for a percentage of 87.4%, the system interface is very attractive and the information provided is very clear. …”
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6453
Comparative safety of the sodium glucose co-transporter 2 (SGLT2) inhibitors: a systematic review and meta-analysis
Published 2019-02-01“…Random effects models were used to estimate pooled relative risks (RRs).Intervention SGLT2 inhibitors, compared with placebo or active comparators.Primary outcomes Acute kidney injury (AKI), diabetic ketoacidosis (DKA), urinary tract infections (UTI), bone fractures and lower limb amputations.Results We screened 2418 citations of which 109 were included. …”
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6454
Perbandingan Kinerja Inception- Resnetv2, Xception, Inception-v3, dan Resnet50 pada Gambar Bentuk Wajah
Published 2023-02-01“…Dalam bidang industri fashion dapat digunakan untuk pemilihan gaya rambut, pemilihan bingkai kacamata, tata rias, dan mode lainnya. Selain itu, dalam bidang medis bentuk wajah digunakan untuk bedah plastik. …”
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6455
Spinally targeted paired associative stimulation with high-frequency peripheral component induces spinal level plasticity in healthy subjects
Published 2024-12-01“…We sought to determine if the TMS-induced orthodromic activation in upper motor neurons and PNS-induced antidromic activation in lower motor neurons arriving simultaneously to the intervening synapses at the spinal cord level can be shown to induce acute changes at the targeted location, unlike an otherwise identical but cortically targeted equivalent. …”
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6456
Insights into simulation-based learning: student and faculty experiences in a PharmD program in Saudi Arabia
Published 2025-02-01“…This study gathered data on three simulation activity formats: computerized, mannequin, and standardized patient role-play simulations. …”
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6457
Comparison of the Journey II bicruciate stabilised (JII-BCS) and GENESIS II total knee arthroplasty for functional ability and motor impairment: the CAPAbility, blinded, randomised...
Published 2023-01-01“…Secondary outcomes were: OKS Activity and Participation Questionnaire, EQ-5D-5L and UCLA Activity scores, Timed Up and Go Test, 6 min walk test, lower limb kinematics and lower limb muscle activity during walking and balance.Results This study found no difference in the OKS between groups. …”
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6458
Rescue of common and rare exon 2 skipping variants of the GAA gene using modified U1 snRNA
Published 2025-02-01“…Abstract Background Pompe disease (PD) is an autosomal recessive lysosomal storage disorder caused by the deficient activity of acid alpha glucosidase (GAA) enzyme due to mutations in the GAA gene. …”
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6459
Staphylococcus aureus-specific TIGIT+ Treg are present in the blood of healthy subjects – a hurdle for vaccination?
Published 2025-02-01“…As compared to polyclonally-activated CD4+ T cells, S. aureus-specific Tcon were enriched for the expression of the Th17-type cytokine genes IL17A, IL22 and IL26, while higher percentages of S. aureus-specific Treg expressed the T Cell Immunoreceptor with Ig and ITIM domains (TIGIT), a pleiotropic immune checkpoint. …”
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6460
Uterine prolapse and related factors in beef cow at the Besuki Animal Health Center, Situbondo regency, East Java, Indonesia
Published 2024-11-01“…The sample consisted of 100 cows that calved in 2020-2022, whose data was obtained from the Department of Animal Husbandry of Situbondo regency, East Java, Indonesia. …”
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