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  1. 6441

    Adapting the Home by Martie Gillen, Pat J. Dasler, Jenny Jump

    Published 2012-11-01
    “…This revised 4-page fact sheet discusses AARP’s 10 basic ideas to increase home safety, how to individualize for each person or activity, how to apply universal design to make homes safer, and assistive devices. …”
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  2. 6442

    Mycorrhizae: Implications for Environmental Remediation and Resource Conservation by Jyotsna Sharma, Andrew V. Ogram, Abid Al-Agely

    Published 2008-04-01
    “…Al-Agely, describes the symbiotic relationships between plant roots and fungi and how the resulting rhizosphere activity can lead to transformation and removal of polluting compounds from the soil, reduce the need for fertilizer in commercial nurseries, and improve soil structure and health. …”
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  3. 6443

    Mediator kinase inhibition suppresses hyperactive interferon signaling in Down syndrome by Kira A Cozzolino, Lynn Sanford, Samuel Hunter, Kayla Molison, Benjamin Erickson, Meaghan CS Courvan, Taylor Jones, Deepa Ajit, Matthew D Galbraith, Joaquín M Espinosa, David Bentley, Mary Ann Allen, Robin D Dowell, Dylan J Taatjes

    Published 2025-02-01
    “…Using sibling-matched cell lines with/without T21, we investigated Mediator kinase function in the context of hyperactive IFN in DS over a 75 min to 24 hr timeframe. Activation of IFN-response genes was suppressed in cells treated with the CDK8/CDK19 inhibitor cortistatin A (CA), via rapid suppression of IFN-responsive transcription factor (TF) activity. …”
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  4. 6444

    Permafrost pore structure and its influence on microbial diversity: Insights from X-ray computed tomography by Nathan D. Blais, Joy M. O’Brien, Hannah Holland-Moritz, Lauren Farnsworth, Robyn A. Barbato, Thomas A. Douglas, Alexandra Contosta, Julie Bobyock, Erin C. Rooney, Taylor Sullivan, Jessica Gilman Ernakovich

    Published 2025-02-01
    “…Although once thought to be devoid of microbial activity, more recent advances demonstrate permafrost is an active ecosystem albeit less than most unfrozen soil. …”
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  5. 6445

    The AMD-associated genetic polymorphism CFH Y402H confers vulnerability to Hydroquinone-induced stress in iPSC-RPE cells by Angela Armento, Inga Sonntag, Ana-Cristina Almansa-Garcia, Merve Sen, Sylvia Bolz, Blanca Arango-Gonzalez, Ellen Kilger, Ruchi Sharma, Kapil Bharti, Rosario Fernandez-Godino, Berta de la Cerda, Simon J. Clark, Simon J. Clark, Simon J. Clark, Marius Ueffing

    Published 2025-02-01
    “…One of the main genetic risks includes the Y402H polymorphism in complement Factor H (FH), an inhibitor of complement system activation. There has been, and continues to be, much discussion around the functional consequences of this Y402H polymorphism, whether the soluble FH protein confers its risk association, or if the cells expressing the protein themselves are affected by the genetic alteration. …”
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  6. 6446

    Targeting sphingosine 1-phosphate receptor 3 inhibits T-cell exhaustion and regulates recruitment of proinflammatory macrophages to improve antitumor efficacy of CAR-T cells agains... by Weiting Liao, Ge Gao, Xia He, Pei Shu, Qizhi Ma, Benxia Zhang, Diyuan Qin, Yongsheng Wang

    Published 2023-08-01
    “…Mechanistically, the S1PR3 antagonist improved CAR-T cell activation, regulated the central memory phenotype, and reduced CAR-T cell exhaustion in vitro. …”
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  7. 6447

    Parasitic infection prevalence in tuberculosis patients and their household contacts in the Littoral Region of Cameroon by Lucy Cho Nchang, Chefor Magha, Patience Agwa Fonong, Narcisse Victor Tchamatchoua Gandjui, Nancielle Mbiatong Tchatat, Desmond Akumtoh Nkimbeng, Frank Noel Nietcho, Juluis Visnel Foyet, Fanny Fri Fombad, Tatiana Djikeussi Katcho, Jerome Fru Cho, Achim Hoerauf, Manuel Ritter, Samuel Wanji

    Published 2025-02-01
    “…TB patients and household contacts living in urban areas had lower odds of being associated with helminth infections (AOR 0.2, 95 % CI: 0.10–0.40; p ˂ 0.0001 and AOR 0.11, 95 % CI: 0.04–0.27; p ˂ 0.0001 respectively) as compared to those residing in rural areas. …”
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  8. 6448
  9. 6449

    Growth, fat metabolism and hepatic health in largemouth bass fed varying fat-level diets by Digen Qin, Jiale Chen, Junxiong Li, Zhiyou Liu, Weibin Huang, Yuanzhi Yang, Jing Zhang, Beiping Tan, Xiaohui Dong

    Published 2025-03-01
    “…Serum biochemical indexes and serum alanine aminotransferase (ALT) activity, liver glutathione peroxidase (GSH-Px) and catalase (CAT) activities were increased significantly with rising dietary fat levels (P<0.05), serum aspartate transaminase (AST) and liver superoxide dismutase (SOD) activities had no statistical differences (P>0.05). …”
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  10. 6450

    Jaringan Komunitas Berbasis Similaritas Topik Bahasan dan Emosi untuk Mengidentifikasi Perilaku Pengguna Twitter by Apriantoni Apriantoni, Diana Purwitasari, Agus Budi Raharjo

    Published 2023-02-01
    “…Based on the analysis of 121 active users, before the COVID-19 period had 98 representative users, who were dominated by 33% of community behavior related to personal activities with happy emotions. …”
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  11. 6451
  12. 6452

    Model Sistem Berbasis Pengetahuan untuk Rekomendasi Aktivitas Pensiun by Dono Catur Prasetyo, Sri Kusumadewi, Isnatin Miladiyah

    Published 2021-10-01
    “…The use of these two methods aims to provide better results in providing recommendations for retirement activities. The results of this study after testing the User Acceptance Test (UAT) of 30 respondents on the system resulted in the conclusion that this system helps provide recommendations of activities for retirement preparation for a percentage of 87.4%, the system interface is very attractive and the information provided is very clear. …”
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  13. 6453

    Comparative safety of the sodium glucose co-transporter 2 (SGLT2) inhibitors: a systematic review and meta-analysis by Kris Aubrey-Bassler, John-Michael Gamble, Jennifer R Donnan, Catherine A Grandy, Eugene Chibrikov, Carlo A Marra, Karissa Johnston, Michelle Swab, Jenna Hache, Daniel Curnew, Hai Nguyen

    Published 2019-02-01
    “…Random effects models were used to estimate pooled relative risks (RRs).Intervention SGLT2 inhibitors, compared with placebo or active comparators.Primary outcomes Acute kidney injury (AKI), diabetic ketoacidosis (DKA), urinary tract infections (UTI), bone fractures and lower limb amputations.Results We screened 2418 citations of which 109 were included. …”
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  14. 6454

    Perbandingan Kinerja Inception- Resnetv2, Xception, Inception-v3, dan Resnet50 pada Gambar Bentuk Wajah by Fitriana Masruroh, Bayu Surarso, Budi Warsito

    Published 2023-02-01
    “…Dalam bidang industri fashion dapat digunakan untuk pemilihan gaya rambut, pemilihan bingkai kacamata, tata rias, dan mode lainnya. Selain itu, dalam bidang medis bentuk wajah digunakan untuk bedah plastik. …”
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  15. 6455

    Spinally targeted paired associative stimulation with high-frequency peripheral component induces spinal level plasticity in healthy subjects by Anna Nätkynmäki, Leena Lauronen, Piia Haakana, Erika Kirveskari, Janne Avela, Anastasia Shulga

    Published 2024-12-01
    “…We sought to determine if the TMS-induced orthodromic activation in upper motor neurons and PNS-induced antidromic activation in lower motor neurons arriving simultaneously to the intervening synapses at the spinal cord level can be shown to induce acute changes at the targeted location, unlike an otherwise identical but cortically targeted equivalent. …”
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  16. 6456
  17. 6457

    Comparison of the Journey II bicruciate stabilised (JII-BCS) and GENESIS II total knee arthroplasty for functional ability and motor impairment: the CAPAbility, blinded, randomised... by Allan B Clark, Toby O Smith, J Wells, Iain McNamara, Juliet High, Ann Marie Swart, Valerie Pomeroy, Graham Creelman, Celia Whitehouse, B Harry, Celia Clarke

    Published 2023-01-01
    “…Secondary outcomes were: OKS Activity and Participation Questionnaire, EQ-5D-5L and UCLA Activity scores, Timed Up and Go Test, 6 min walk test, lower limb kinematics and lower limb muscle activity during walking and balance.Results This study found no difference in the OKS between groups. …”
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  18. 6458

    Rescue of common and rare exon 2 skipping variants of the GAA gene using modified U1 snRNA by Paolo Peruzzo, Natascha Bergamin, Martina Bon, Sara Cappelli, Alessandra Longo, Elisa Goina, Cristiana Stuani, Emanuele Buratti, Andrea Dardis

    Published 2025-02-01
    “…Abstract Background Pompe disease (PD) is an autosomal recessive lysosomal storage disorder caused by the deficient activity of acid alpha glucosidase (GAA) enzyme due to mutations in the GAA gene. …”
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  19. 6459

    Staphylococcus aureus-specific TIGIT+ Treg are present in the blood of healthy subjects – a hurdle for vaccination? by Jonah Clegg, Jonah Clegg, Malgorzata E. Mnich, Malgorzata E. Mnich, Alberto Carignano, Giovanni Cova, Simona Tavarini, Chiara Sammicheli, Bruna Clemente, Megan Smith, Megan Smith, Emilio Siena, Monia Bardelli, Michela Brazzoli, Fabio Bagnoli, Rachel M. McLoughlin, Elisabetta Soldaini

    Published 2025-02-01
    “…As compared to polyclonally-activated CD4+ T cells, S. aureus-specific Tcon were enriched for the expression of the Th17-type cytokine genes IL17A, IL22 and IL26, while higher percentages of S. aureus-specific Treg expressed the T Cell Immunoreceptor with Ig and ITIM domains (TIGIT), a pleiotropic immune checkpoint. …”
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  20. 6460

    Uterine prolapse and related factors in beef cow at the Besuki Animal Health Center, Situbondo regency, East Java, Indonesia by Kevin Mardotillah, Suzanita Utama, Erma Safitri, Herry Agoes Hermadi, Sri Pantja Madyawati, Djoko Legowo, Abdullah Hasib

    Published 2024-11-01
    “…The sample consisted of 100 cows that calved in 2020-2022, whose data was obtained from the Department of Animal Husbandry of Situbondo regency, East Java, Indonesia. …”
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