Prevalence, Treatment, and Unmet Needs of Migraine in the Middle East: A Systematic Review by Taoufik Alsaadi, AbuBakar Al Madani, Mohammed Alhatou, Mona Nada, Abdulrazaq Albilali, Ahmed Al-Qassabi, Hegab Mohamed, Haytham Mohamed, Rowan El Masry, Ghaidaa Ahmed Saifuddin, Suhail Abdullah AlRukn

“…Abstract Introduction Migraine is a debilitating neurological disorder characterized by recurrent throbbing, moderate-to-severe headaches that disrupt daily chores, leisure, and social activities of patients, impacting their overall quality of life (QoL). …”
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S100A8-CAMKK2-AMPK axis confers the protective effects of mild hypothermia against cerebral ischemia-reperfusion injury in rats by Dandan Zhang, Yuting Dai, Xiaoyan Xu, Fuguo Ma, Mingshan Wang, Weiwei Qin

“…Mechanistically, MH down-regulated S100A8 expression, enhancing mitochondrial function via activation of the CAMKK2/AMPK signaling pathway. Moreover, with MH treatment, the administration of CAMKK2 and AMPK inhibitors STO-609 and Dorsomorphin significantly increased oxidative stress, mitochondrial damage, and cell apoptosis, thereby diminishing MH’s neuroprotective effect against cerebral IR injury. …”
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Achieving Medication‐Free Remission in Patients With Juvenile Dermatomyositis by Ilaria Maccora, Hermine I. Brunner, Amy Cassedy, Mekibib Altaye, Megan Quinlan‐Waters, Daniel J. Lovell, Alexei Grom, Sheila T. Angeles‐Han

“…Diagnosis of JDM before 5 years old (odds ratio 4.5, 95% confidence interval [CI] 1.2–16.7) was the only predictor of MFR in our multivariate model (area under the curve 0.65, 95% CI 0.53–0.76). …”
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Dietary Histidine Supplementation Maintained Amino Acid Homeostasis and Reduced Hepatic Lipid Accumulation of Juvenile Largemouth Bass, Micropterus Salmoides by Hualiang Liang, Gangchun Xu, Pao Xu, Jian Zhu, Songlin Li, Mingchun Ren

“…In general, histidine supplementation promoted protein synthesis and lipid decomposition and reduced lipid synthesis by activating the TOR, AAR, PPARα, and PPARγ signaling pathways, which provided a new perspective to solve the fatty liver problem of largemouth bass by nutritional means.…”
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Quantifying uncertainty in anthropogenic causes of injury and mortality for an endangered baleen whale by Daniel W. Linden, Jeffrey A. Hostetler, Richard M. Pace III, Lance P. Garrison, Amy R. Knowlton, Véronique Lesage, Rob Williams, Michael C. Runge

“…We found strong evidence for increased rates of severe entanglement injuries after 2013 and for females with calves, with consequently higher marginal mortality. …”
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Synovial sarcoma. Evaluation of Prognosis with Emphasis on the Study of DNA Ploidy and Proliferation (PCNA and Ki-67) Markers by José M. Lopes, Einar Hannisdal, Bodil Bjerkehagen, Øyvind S. Bruland, Håvard E. Danielsen, Erik O. Pettersend, Manuel Sobrinho-Simões, Jahn M. Nesland

“…We investigated the relationship between (flow and image) DNA cytometry, proliferation activity, clinicopathologic parameters, and relapse-free and overall survival of the patients. …”
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Microscopic Analysis of Temperature Effects on Surface Colonization and Biofilm Morphology of <i>Salmonella enterica</i> by Zachariah Vice, You Zhou, Sapna Chitlapilly Dass, Rong Wang

“…These results demonstrate that the environmental temperature significantly contributes to <i>S. enterica</i> biofilm formation as the higher temperatures encourage bacterial active proliferation and biofilm maturation leading to the development of well-pronounced structures, while the lower temperature may promote cell attachment but, meanwhile, limit the EPS biosynthesis and biofilm maturation. …”
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Factors influencing reselection of village doctors in rural-oriented tuition-waived medical education program in Shanghai, China: a cross-sectional study by Jing Gao, Juhua Zhang, Chenlei Shi, Aiqin Fan, Peng Zhang

“…Factors influencing reselection included “Volunteering to serve the grassroots people” (odds ratio [OR], 2.29 [95% confidence interval {CI}, 1.22–4.30]), “Enjoying the medical profession” (OR, 2.64 [95%CI, 1.33–5.27]), not fulfilling family wishes (OR, 0.47 [95%CI, 0.24–0.88]), Satisfied with the current salary (OR, 2.39 [95%CI, 1.27–4.49]). …”
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MATHEMATICAL RATIONALE FOR CREATING AN APPLICATION FOR CONDUCTING RANDOM MEETINGS «COFFEE BREAK» by Vadym Ziuziun, Daniil Osoka

“…These interactions help raise awareness about the activities in other departments and foster informal and professional connections. …”
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Interpretation of Recent Unrest Events (Bradyseism) at Campi Flegrei, Napoli (Italy): Comparison of Models Based on Cyclical Hydrothermal Events versus Shallow Magmatic Intrusive E... by A. Lima, R. J. Bodnar, B. De Vivo, F. J. Spera, H. E. Belkin

“…CF bradyseism events are driven by cyclical magmatic-hydrothermal activity. Bradyseism events are characterized by cyclical, constant invariant signals repeating over time, such as area deformation along with a spatially well-defined seismogenic volume. …”
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Haemophagocytic lymphohistiocytosis in patients treated with immune checkpoint inhibitors: analysis of WHO global database of individual case safety reports by Alessandro Ceschi, Roberta Noseda, Raffaela Bertoli, Laura Müller

“…Background Immune checkpoint inhibitor (ICI) use in clinical practice has unravelled a spectrum of immune-related adverse events (irAEs) due to immune system hyper-activation. ICI-related haemophagocytic lymphohistiocytosis (HLH) has been recently outlined in single case reports, raising a concern about the need of increasing our knowledge on this rare yet life threatening ICI haematological toxicity.Methods To determine ICI-related HLH clinical, haematological, and coagulation features, its timing and outcome, concurrent irAEs and concomitant infections, we performed a retrospective observational cross-sectional study and queried VigiBase, the WHO global database of suspected adverse drug reactions (ADRs), on September 30th, 2018. …”
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Relationship between motivational climate, anxiety and average mark in pre-service physical education teachers: a cross-sectional study based on structural equation modelling appro... by Eduardo Melguizo-Ibáñez, Gabriel González-Valero, Georgian Badicu, Fatma Hilal Yagin, José Manuel Alonso-Vargas, Luca Paolo Ardigò, Pilar Puertas-Molero

“…Likewise, the branch of study of the sample is related to university degrees in education sciences and physical activity and sport sciences. The Beck Anxiety Inventory (BAI), Perceived Motivational Climate in Sport-2 and an ad hoc socio-demographic questionnaire were used to collect the data. …”
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An eCIRP inhibitor attenuates fibrosis and ferroptosis in ischemia and reperfusion induced chronic kidney disease by Fangming Zhang, Zhijian Hu, Asha Jacob, Max Brenner, Ping Wang

Subjects: “…eCIRP…”
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Investigation of the Ternary System, Water/Hydrochloric Acid/Polyamide 66, for the Production of Polymeric Membranes by Phase Inversion by Jocelei Duarte, Camila Suliani Raota, Camila Baldasso, Venina dos Santos, Mara Zeni

“…The theoretical cloud point curve was calculated based on “Boom’s LCP Correlation” and compared to the curve of the experimental cloud point. …”
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Comparative effects of gong’s mobilization and mobilization with movement in patients with adhesive capsulitis: a randomized clinical trial by Fareeha Amjad, Hasha Asghar

“…Abstract Adhesive Capsulitis results in a progressive contraction of the Glenohumeral joint capsule limiting active and passive range of motion, leading to functional disabilities. …”
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Inflammasome Genes’ Polymorphisms in Egyptian Chronic Hepatitis C Patients: Influence on Vulnerability to Infection and Response to Treatment by Shady Z. K. Estfanous, Sahar A. Ali, Sameh M. Seif, Sameh H. A. Soror, Dalia H. A. Abdelaziz

“…The NOD-like receptor, pyrin domain-containing 3 (NLRP3) inflammasome is activated by HCV in both hepatocytes and Kupffer cells. …”
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Development of specialist palliative care in Dutch hospitals between 2014 and 2020: a repeated survey by N. van Velzen, L. Brom, M. J. D. L van der Vorst, M. L. Kiers, M. F. M. Wagemans, H. Kazimier, M. S. A. Boddaert, N. J. H. Raijmakers, A. Stoppelenburg

“…The SPCTs have developed significantly in various aspects, including collaboration between primary and hospital care, the availability of services to patients at home and non-clinical activities. Conclusion Over the years, Dutch hospitals have shown growth in hospital-wide integration of specialist PC. …”
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Qalification assessment practices: new possibilities and constraints by M. N. Kicherova, M. Yu. Semenov, E. V. Zyuban

“…The methodological framework of the research is based on the principles of the activity approach and the concept of structuration, in which the practice of qualifications assessment is viewed as a combination of social relations between individual and collective actors in the space of social and labour relations. …”
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Alleviatory efficacy of achillea millefolium L. in etoxazole-mediated toxicity in allium cepa L by Zeynep Şule Topatan, Tuğçe Kalefetoğlu Macar, Oksal Macar, Emine Yalçin, Kültiğin Çavuşoğlu, Ali Acar, Fatih Kutluer

“…The levels of malondialdehyde and antioxidant enzyme (superoxide dismutase and catalase) activities were also elevated. Epidermis cell damage, flattened cell nucleus, thickened cortex cell wall, and thickened conduction tissue were the meristematic cell disorders triggered by etoxazole. …”
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Occurrence and Variations of Middle and Low Latitude Sporadic E Layer Investigated With Longitudinal and Latitudinal Chains of Ionosondes by Qiong Tang, Jiaqi Zhao, Zhibin Yu, Yi Liu, Lianhuan Hu, Chen Zhou, Zhengyu Zhao, Xueshang Feng

“…Solar and geomagnetic activities can also result in periodic variations of the Es.…”
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