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64381
A Machine Learning Approach Using Topic Modeling to Identify and Assess Experiences of Patients With Colorectal Cancer: Explorative Study
Published 2025-01-01“…Dominant clusters included “Daily activities while living with CRC” (38,782, 18.3%) and “Understanding treatment including alternatives and adjuvant therapy” (31,577, 14.9%). …”
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64382
Curcumin nanoparticles alleviate brain mitochondrial dysfunction and cellular senescence in γ-irradiated rats
Published 2025-01-01“…Moreover, CNPs administered to irradiated rats significantly reduced brain β-galactosidase activity and the expression levels of p53, p21, and p16 genes (P < 0.05) while concurrently inducing a significant increase in AMPK mRNA expression compared to the irradiated group. …”
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64383
AcfA Regulates the Virulence and Cell Envelope Stress Response of <i>Vibrio parahaemolyticus</i>
Published 2024-12-01“…The deletion of <i>acfA</i> had no effect on bacterial growth but resulted in a significant reduction in biofilm formation, hemolytic activity, mucus adhesion, and the accumulated mortality of zebrafish, compared to the wild-type strain and the complementary strain <i>acfA</i><sup>+</sup>. …”
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64384
Metagenomic analysis post thermal stress in buffalo sludge and tomato pomace anaerobic digestion: a case study
Published 2023-11-01“…Buffalo farming represents a relevant sector within Italian agriculture, and one of its main issues is manure management. Both economic activities generate a substantial amount of waste (buffalo sludge - BS and tomato pomace – TP, peels plus seeds) that can significantly impact the disposal costs and, hence, their economic and environmental sustainability. …”
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64385
Conceptual Principles of State Policy in the Field of Higher Education in Ukraine: Administrative and Legal Aspect
Published 2020-06-01“…That allowed to determine its characteristic features that distinguish it from other types of state policy in general and state educational policy in particular. …”
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64386
Sex-specific differences in the efficacy of renal denervation in patients with resistant hypertension depending on visceral obesity and kidney function
Published 2025-01-01“…ObjectiveTo investigate the sex differences in the efficacy of renal denervation (RDN) in patients with resistant hypertension (RHT) concerning the size of abdominal fat depots, changes in biomarkers of sympathetic activity, and renal function.Materials and methods24 men (56.5 ± 7.8 years) and 33 women (59.5 ± 8.4 years) with RHT were enrolled in the study and underwent RDN. 24-h ambulatory blood pressure (BP) [systolic/diastolic (SBP/DBP)], serum creatinine (with eGFR calculation), serum adipocytokines (leptin, adiponectin, resistin), serum metanephrines and normetanephrines were measured baseline and 12 months after RDN. …”
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64387
The Link between Overweight/Obesity and Noncommunicable Diseases in Ethiopia: Evidences from Nationwide WHO STEPS Survey 2015
Published 2023-01-01“…Among the 9,800 participants, 2053 (21% with (95% CI: 19.8–22.1) had hypertension and 1368 (14% with (95% CI: 13.1–15.0) had high cholesterol levels. …”
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64388
KULTŪRINIO IR SIMBOLINIO KAPITALO GAMYBA: "DISNEY" FENOMENAS
Published 2003-01-01“…Humanistic and individualistic activities of Disney corporation's creation, co-operation with consumers, and development of education programs are emphasized in the article. …”
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64389
Discovery and development of ANV419, an IL-2/anti-IL-2 antibody fusion protein with potent CD8+ T and natural killer cell-stimulating capacity for cancer immunotherapy
Published 2024-12-01“…Here we describe ANV419, an IL-2/anti-IL2 antibody fusion protein designed for selective IL-2 receptor βγ (IL-2 Rβγ) activation by sterically hindering IL-2 from binding to IL-2 Rα. …”
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64390
Obesity-induced mesenteric PVAT remodelling is sexually dimorphic, but not driven by ovarian hormones
Published 2025-01-01“…Perivascular adipose tissue (PVAT), a metabolically active tissue surrounding blood vessels, plays a key role in regulating vascular tone. …”
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64391
Hepatocyte Rho-associated kinase signaling is required for mice to survive experimental porphyria-associated liver injury
Published 2025-02-01“…Correspondingly, there was increased hepatocyte nuclear localization of p21 and expression of cleaved caspase-3 in DDC-injured DKO liver, consistent with the activation of p21-mediated caspase-3–dependent apoptotic cell death pathways. …”
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64392
Ethnopharmocology, phytochemistry and pharmacology of the genus Orthosiphon: A review
Published 2025-02-01“…Despite substantial bias in attention among various species of the genus Orthosiphon, its potential as health food and therapeutic agents is evident. …”
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64393
Factores determinantes y propuestas para la gestión de la innovación en las empresas constructoras Determinant issues and proposals for the management of innovation in construction...
Published 2007-04-01“…This model states the need to ease the information flow inside the organization, thus the knowledge generated by innovation in construction sites allows a substantial raise in the business competitiveness. …”
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64394
FOSL1 transcriptionally dictates the Warburg effect and enhances chemoresistance in triple-negative breast cancer
Published 2025-01-01“…Mechanistically, FOSL1 transcriptionally activates the expression of genes such as SLC2A1, ENO1, and LDHA, which further accelerate the glycolytic flux. …”
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64395
Trichinella spiralis excretory/secretory proteins mediated larval invasion via inducing gut epithelial apoptosis and barrier disruption.
Published 2025-01-01“…The results of trans-epithelial electrical resistance (TEER) and FITC-dextran showed that IIL ESP decreased the TEER, increased FITC-dextran flux in Caco-2 monolayer. qPCR, Western blot and immunofluorescence test (IFT) showed that IIL ESP decreased the mRNA and protein expression of TJs (ZO-1, E-cad, Occludin and Claudin-1). …”
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64396
Geomatics and metaverse for lost heritage sites documentation and dissemination: the case study of Palmyra Roman Theatre (Syria)
Published 2024-11-01“…Unfortunately, in addition to natural and environmental degradation, human activities pose a significant threat to the integrity of historical sites. …”
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64397
Production technology of poultry sausage-1: the studies on the quality of chemical, microbiological and organoleptic
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64398
Impact of the five-pattern personality traits of traditional Chinese medicine on workplace violence and depression among nurses
Published 2025-01-01“…At the same time, it is necessary to actively cultivate excellent personality traits in nurses to reduce the frequency of WPV and improve their mental health.…”
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64399
The association between consumption of ultra-processed foods and sperm quality parameters: a cross-sectional study
Published 2025-02-01“…However, after adjusting for age, marriage duration, body mass index, physical activity, depression, anxiety, stress, energy intake, cigarette history, and mineral and vitamin supplements, a significantly higher association was identified between the second tertile of UPFs and abnormalities in sperm concentration (odds ratio (OR) = 3.962, 95% confidence interval (CI): 1.345–11.670, p = 0.013). …”
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64400
Effects of the Replacement of Dietary Fishmeal by the Blend of Tenebrio molitor Meal, Chlorella Meal, Clostridium Autoethanogenum Protein, and Cottonseed Protein Concentrate on Gro...
Published 2024-01-01“…And it also significantly increased intestinal trypsin activity (P<0.05), upregulated the mRNA expression of amino acid sensory receptor-related and amino acid or peptide transport-related genes (P<0.05), increased protein apparent digestibility coefficient (P<0.05). …”
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