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  1. 64381

    A Machine Learning Approach Using Topic Modeling to Identify and Assess Experiences of Patients With Colorectal Cancer: Explorative Study by Kelly Voigt, Yingtao Sun, Ayush Patandin, Johanna Hendriks, Richard Hendrik Goossens, Cornelis Verhoef, Olga Husson, Dirk Grünhagen, Jiwon Jung

    Published 2025-01-01
    “…Dominant clusters included “Daily activities while living with CRC” (38,782, 18.3%) and “Understanding treatment including alternatives and adjuvant therapy” (31,577, 14.9%). …”
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  2. 64382

    Curcumin nanoparticles alleviate brain mitochondrial dysfunction and cellular senescence in γ-irradiated rats by Omnia A. Moselhy, Nahed Abdel-Aziz, Azza El-bahkery, Said S. Moselhy, Ehab A. Ibrahim

    Published 2025-01-01
    “…Moreover, CNPs administered to irradiated rats significantly reduced brain β-galactosidase activity and the expression levels of p53, p21, and p16 genes (P < 0.05) while concurrently inducing a significant increase in AMPK mRNA expression compared to the irradiated group. …”
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  3. 64383

    AcfA Regulates the Virulence and Cell Envelope Stress Response of <i>Vibrio parahaemolyticus</i> by Huan Liu, Huayu Lei, Juanjuan Cao, Zhaobang Xie, Yile Shi, Yanni Zhao

    Published 2024-12-01
    “…The deletion of <i>acfA</i> had no effect on bacterial growth but resulted in a significant reduction in biofilm formation, hemolytic activity, mucus adhesion, and the accumulated mortality of zebrafish, compared to the wild-type strain and the complementary strain <i>acfA</i><sup>+</sup>. …”
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  4. 64384

    Metagenomic analysis post thermal stress in buffalo sludge and tomato pomace anaerobic digestion: a case study by Maria Chiara La Mantia

    Published 2023-11-01
    “…Buffalo farming represents a relevant sector within Italian agriculture, and one of its main issues is manure management. Both economic activities generate a substantial amount of waste (buffalo sludge - BS and tomato pomace – TP, peels plus seeds) that can significantly impact the disposal costs and, hence, their economic and environmental sustainability. …”
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  5. 64385

    Conceptual Principles of State Policy in the Field of Higher Education in Ukraine: Administrative and Legal Aspect by V. V. Abroskin

    Published 2020-06-01
    “…That allowed to determine its characteristic features that distinguish it from other types of state policy in general and state educational policy in particular. …”
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  6. 64386

    Sex-specific differences in the efficacy of renal denervation in patients with resistant hypertension depending on visceral obesity and kidney function by Irina Zyubanova, Nadezhda Ryumshina, Victor Mordovin, Musheg Manukyan, Valeriya Lichikaki, Ekaterina Solonskaya, Anna Gusakova, Tatjana Suslova, Stanislav Pekarskiy, Simzhit Khunkhinova, Anastasia Popova, Veronika Rudenko, Alla Falkovskaya

    Published 2025-01-01
    “…ObjectiveTo investigate the sex differences in the efficacy of renal denervation (RDN) in patients with resistant hypertension (RHT) concerning the size of abdominal fat depots, changes in biomarkers of sympathetic activity, and renal function.Materials and methods24 men (56.5 ± 7.8 years) and 33 women (59.5 ± 8.4 years) with RHT were enrolled in the study and underwent RDN. 24-h ambulatory blood pressure (BP) [systolic/diastolic (SBP/DBP)], serum creatinine (with eGFR calculation), serum adipocytokines (leptin, adiponectin, resistin), serum metanephrines and normetanephrines were measured baseline and 12 months after RDN. …”
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  7. 64387

    The Link between Overweight/Obesity and Noncommunicable Diseases in Ethiopia: Evidences from Nationwide WHO STEPS Survey 2015 by Bedilu Alamirie Ejigu, Fentanesh Nibret Tiruneh

    Published 2023-01-01
    “…Among the 9,800 participants, 2053 (21% with (95% CI: 19.8–22.1) had hypertension and 1368 (14% with (95% CI: 13.1–15.0) had high cholesterol levels. …”
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  8. 64388

    KULTŪRINIO IR SIMBOLINIO KAPITALO GAMYBA: "DISNEY" FENOMENAS by Gintautas Mažeikis

    Published 2003-01-01
    “…Humanistic and individualistic activities of Disney corporation's creation, co-operation with consumers, and development of education programs are emphasized in the article. …”
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  9. 64389

    Discovery and development of ANV419, an IL-2/anti-IL-2 antibody fusion protein with potent CD8+ T and natural killer cell-stimulating capacity for cancer immunotherapy by Patrizia Murer, Barbara Brannetti, Jean-Michel Rondeau, Laetitia Petersen, Nicole Egli, Simone Popp, Catherine Regnier, Kirsten Richter, Andreas Katopodis, Christoph Huber

    Published 2024-12-01
    “…Here we describe ANV419, an IL-2/anti-IL2 antibody fusion protein designed for selective IL-2 receptor βγ (IL-2 Rβγ) activation by sterically hindering IL-2 from binding to IL-2 Rα. …”
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  10. 64390

    Obesity-induced mesenteric PVAT remodelling is sexually dimorphic, but not driven by ovarian hormones by Lisa Ivatt, Mhairi Paul, Allende Miguelez-Crespo, Patrick W. F. Hadoke, Matthew A. Bailey, Ruth A. Morgan, Mark Nixon

    Published 2025-01-01
    “…Perivascular adipose tissue (PVAT), a metabolically active tissue surrounding blood vessels, plays a key role in regulating vascular tone. …”
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  11. 64391

    Hepatocyte Rho-associated kinase signaling is required for mice to survive experimental porphyria-associated liver injury by Jessica M. Herrera, Yun Weng, Tyler J. Lieberthal, Marcus Paoletti, Tammy T. Chang

    Published 2025-02-01
    “…Correspondingly, there was increased hepatocyte nuclear localization of p21 and expression of cleaved caspase-3 in DDC-injured DKO liver, consistent with the activation of p21-mediated caspase-3–dependent apoptotic cell death pathways. …”
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  12. 64392

    Ethnopharmocology, phytochemistry and pharmacology of the genus Orthosiphon: A review by Rui Wang, Ling Qiu, Qing-wen Zhang, Ligen Lin

    Published 2025-02-01
    “…Despite substantial bias in attention among various species of the genus Orthosiphon, its potential as health food and therapeutic agents is evident. …”
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  13. 64393

    Factores determinantes y propuestas para la gestión de la innovación en las empresas constructoras Determinant issues and proposals for the management of innovation in construction... by Christian L Correa, Víctor Yepes, Eugenio Pellicer

    Published 2007-04-01
    “…This model states the need to ease the information flow inside the organization, thus the knowledge generated by innovation in construction sites allows a substantial raise in the business competitiveness. …”
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  14. 64394

    FOSL1 transcriptionally dictates the Warburg effect and enhances chemoresistance in triple-negative breast cancer by Gang Zhao, Yutong Liu, Shiqi Yin, Runxiang Cao, Qian Zhao, Yifan Fu, Ye Du

    Published 2025-01-01
    “…Mechanistically, FOSL1 transcriptionally activates the expression of genes such as SLC2A1, ENO1, and LDHA, which further accelerate the glycolytic flux. …”
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  15. 64395

    Trichinella spiralis excretory/secretory proteins mediated larval invasion via inducing gut epithelial apoptosis and barrier disruption. by Qi Qi Lu, Wen Wen Zheng, Zhao Yu Zhang, Pei Kun Cong, Xin Guo, Yao Zhang, Xin Zhuo Zhang, Shao Rong Long, Ruo Dan Liu, Zhong Quan Wang, Jing Cui

    Published 2025-01-01
    “…The results of trans-epithelial electrical resistance (TEER) and FITC-dextran showed that IIL ESP decreased the TEER, increased FITC-dextran flux in Caco-2 monolayer. qPCR, Western blot and immunofluorescence test (IFT) showed that IIL ESP decreased the mRNA and protein expression of TJs (ZO-1, E-cad, Occludin and Claudin-1). …”
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  16. 64396

    Geomatics and metaverse for lost heritage sites documentation and dissemination: the case study of Palmyra Roman Theatre (Syria) by Anna Forte, Yara Jamil Alkhatib, Gabriele Bitelli, Eva Savina Malinverni, Roberto Pierdicca

    Published 2024-11-01
    “…Unfortunately, in addition to natural and environmental degradation, human activities pose a significant threat to the integrity of historical sites. …”
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  17. 64397

    Production technology of poultry sausage-1: the studies on the quality of chemical, microbiological and organoleptic by Nazif Anıl, Yusuf Doğruer, Ümit Gürbüz, Semra Kayaardı, Abdullah Keleş

    “…This study was carried out for producing a new product "Poultry Sausage" and investigate its quality factors.The poultry sausage used in the experiments was developped by the applications of several tests and trials. …”
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  18. 64398

    Impact of the five-pattern personality traits of traditional Chinese medicine on workplace violence and depression among nurses by ZhiHui Gu, ChenXin Yang, MengYao Li

    Published 2025-01-01
    “…At the same time, it is necessary to actively cultivate excellent personality traits in nurses to reduce the frequency of WPV and improve their mental health.…”
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  19. 64399

    The association between consumption of ultra-processed foods and sperm quality parameters: a cross-sectional study by Mitra Soltani, Mohammad Reza Ahmadi, Zainab Shateri, Zahra Maghsoudi, Milad Rajabzadeh-Dehkordi, Moein Askarpour, Amir Hossein Asadi, Mehran Nouri

    Published 2025-02-01
    “…However, after adjusting for age, marriage duration, body mass index, physical activity, depression, anxiety, stress, energy intake, cigarette history, and mineral and vitamin supplements, a significantly higher association was identified between the second tertile of UPFs and abnormalities in sperm concentration (odds ratio (OR) = 3.962, 95% confidence interval (CI): 1.345–11.670, p = 0.013). …”
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  20. 64400

    Effects of the Replacement of Dietary Fishmeal by the Blend of Tenebrio molitor Meal, Chlorella Meal, Clostridium Autoethanogenum Protein, and Cottonseed Protein Concentrate on Gro... by Yongning Yu, Xing Wang, Junyan Jin, Dong Han, Xiaoming Zhu, Haokun Liu, Zhimin Zhang, Yunxia Yang, Shouqi Xie

    Published 2024-01-01
    “…And it also significantly increased intestinal trypsin activity (P<0.05), upregulated the mRNA expression of amino acid sensory receptor-related and amino acid or peptide transport-related genes (P<0.05), increased protein apparent digestibility coefficient (P<0.05). …”
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