Efficacy of pegylated interferon alfa-2b «Algeron» in the treatment of chronic hepatitis C by M. V. Mayevskaya, O. O. Znoyko, E. A. Klimova, S. L. Maximov, S. N. Kizhlo, N. A. Petrochenkova, F. I. Nagimova, R. A. Ivanov, Yu. N. Linkova, T. V. Chernovskaya

“…In the two main groups the patients received Algeron in the dosage of 1.5 or 2.0 μg/kg/week, in the active control group – PegIntron 1.5 μg/kg/week in combination with ribavirin. …”
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A machine learning model and identification of immune infiltration for chronic obstructive pulmonary disease based on disulfidptosis-related genes by Sijun Li, Qingdong Zhu, Aichun Huang, Yanqun Lan, Xiaoying Wei, Huawei He, Xiayan Meng, Weiwen Li, Yanrong Lin, Shixiong Yang

“…Besides, significant differences in DRGs, immune cells, biological functions, and pathway activities were observed between the two clusters.A nomogram was created to aid in the practical application of clinical procedures. …”
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Explainable Self-Supervised Dynamic Neuroimaging Using Time Reversal by Zafar Iqbal, Md. Mahfuzur Rahman, Usman Mahmood, Qasim Zia, Zening Fu, Vince D. Calhoun, Sergey Plis

“…By aligning model predictions with meaningful temporal patterns in brain activity, TR bridges the gap between deep learning and clinical relevance. …”
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Economic evaluation of integrated services for non-communicable diseases and HIV: costs and client outcomes in rural Malawi by Luckson Dullie, Emily B Wroe, Elizabeth L Dunbar, Noel Kalanga, Lawrence Nazimera, Adarsh Shah, Bright Mailosi, Chiyembekezo Kachimanga, Ryan K McBain, Natalie Price, Mahlet Gizaw, Chantelle Boudreaux, Liberty Neba

“…Objective To evaluate the costs and client outcomes associated with integrating screening and treatment for non-communicable diseases (NCDs) into HIV services in a rural and remote part in southeastern Africa.Design Prospective cohort study.Setting Primary and secondary level health facilities in Neno District, Malawi.Participants New adult enrollees in Integrated Chronic Care Clinics (IC3) between July 2016 and June 2017.Main outcome measures We quantified the annualised total and per capita economic cost (US$2017) of integrated chronic care, using activity-based costing from a health system perspective. …”
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The Role of Pyroptosis‐Related Gene Signature and Immune Infiltration in Juvenile Dermatomyositis by Qiao W, Zhu C, Huang D, Liu Y, Wang Z, Zhu T, Song Q, Yang X, Wang Y, Wang Y

“…These genes were involved in cytokine production, inflammasome activity, necroptosis, NOD-like receptor signaling, and TNF signaling. …”
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Astrocyte-Derived Interleukin 11 Modulates Astrocyte–Microglia Crosstalk via Nuclear Factor-κB Signaling Pathway in Sepsis-Associated Encephalopathy by Dandan Zhu, Peng Wang, Xiyue Chen, Kaituo Wang, Yunsong Wu, Min Zhang, Jianhua Qin

“…Here, we found that activated astrocytes and microglia exhibited close spatial interaction in the SAE mouse model. …”
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An Analysis of Land Use Conflicts and Strategies in the Harbin–Changchun Urban Agglomeration Based on the Production–Ecological–Living Space Theory and Patch-Generating Land Use Si... by Xiaomeng Wang, Yanjun Zhang, Xiaoyan Li, Shuwen Cao

“…In recent years, rapid economic development, increasing human activities, and global climate change have led to escalating demands for land across production, residential, and ecological domains. …”
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Remineralising Effects of L-arginine Fluoride Mouthwash versus Sodium Fluoride Mouthwash: A Protocol of an In-vitro Study by Anjori Ajinkya Raut, Punit Ratnakar Fulzele

“…Aim: To assess the remineralising activity of L-arginine fluoride mouthwash compared to sodium fluoride mouthwash. …”
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Secondary prevention of preeclampsia by Muhammad Ilham Aldika Akbar, Muhammad Ilham Aldika Akbar, Roudhona Rosaudyn, Khanisyah Erza Gumilar, Khanisyah Erza Gumilar, Renuka Shanmugalingam, Gustaaf Dekker, Gustaaf Dekker

“…Metformin, primarily used for improving insulin sensitivity, has potential advantages in decreasing PE incidence due to its anti-inflammatory and vascular properties, particularly in morbidly obese women. …”
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Investigation of the preventive effect of methylsulfonylmethane on alveolar bone loss and oxidative stress in a rat model of periodontitis by Melek Beder, Hatice Yemenoglu, Semih Alperen Bostan, Oğuz Kose, Sibel Mataracı Karakas, Tolga Mercantepe, Adnan Yılmaz, Levent Tumkaya

“…Histomorphometric and immunohistochemical (receptor activator of nuclear factor kappa B ligand (RANKL), osteoprotegerin (OPG)) evaluations were performed on right mandibular tissue samples, and biochemical (interleukin (IL)-1 beta (β)/IL-10, malondialdehyde (MDA), glutathione (GSH), oxidative stress index (OSI)) evaluations were performed on left mandibular tissue samples. …”
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INTRODUZIONE ALLA LINGUA INGLESE FIN DALLA PRIMA INFANZIA: UN APPROCCIO BASATO SULL’USO “AMPLIFICATO” DEL CANALE VISIVO-GESTUALE by Erika Raniolo

“…The approach was tested within a project conducted in the province of Ragusa in the s.y. 2022/2023, with participants aged between 3 months and 8 years. The proposed activities show an improvement in understanding and producing the English language. …”
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TO THE BASICS OF MODERN POLITICAL ANTHROPOLOGY: FREEDOM AND JUSTICE IN THE SOCIAL CONTRACT THEORY OF T. HOBBES by L. A. Sytnichenko, D. V. Usov

“…The principle of social contract offered by Hobbes became a new social, methodologically significant and relevant principle of regulation of activity, which indicates essential for the modern political philosophy and the philosophy of law transition from teleological (ancient and medieval) to legal (modern) ideas of justice. …”
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Experiences at recovery community centers predict holistic recovery outcomes: a daily diary assessment of RCC helpfulness, meaningfulness, and recovery identity by Hannah B. Apsley, Joseph Lancaster, Wen Ren, Timothy Brick, H. H. Cleveland

“…IntroductionRecovery community centers (RCCs) offer various support services to people in addiction recovery, such as hosting mutual help meetings and sober social activities and providing employment support and recovery coaching. …”
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Trauma Volume and Performance of a regional Trauma Center in Korea: Initial 5-year analysis by Byungchul Yu, Giljae Lee, Min A Lee, Kangkook Choi, Sungyoul Hyun, Yangbin Jeon, Yong-Cheol Yoon, Jungnam Lee

“…Conclusions The trauma volume in the regional trauma center is appropriate, and some improvements could be observed after its establishment. However, performance indicators reveal the prematurity of the trauma center and its potential for further improvements. …”
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Cost-effectiveness analysis of labour protection measures by E. A. Korol’, E. N. Degaev

“…Construction remains one of the most dangerous economic activities. During construction, workers face various risks that can lead to injuries, including falls from a height, cuts from sharp objects, bruises from falling heavy objects, and others. …”
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Expatriation-enhanced competencies: A multiple case study of technology-based entrepreneurs by Hilka Pelizza Vier Machado, Jörg Freiling

“…FINDINGS: Data allows structuring techpreneurs’ experience of expatriation along the following steps: (a) arrival in the destination country and initial process of socialization, (b) engaging in activities to get familiar with the culture of the destination country, (c) the gradual comprehensive understanding of the new context, and (d) comparisons between the home and destination country. …”
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Evaluation of the Management of Patients with Detectable Viral Load after the Implementation of Routine Viral Load Monitoring in an Urban HIV Clinic in Uganda by Nsumba Steven Mark, Musomba Rachel, Arvind Kaimal, Mubiru Frank, Tibakabikoba Harriet, Lwanga Isaac, Mohammed Lamorde, Castelnuovo Barbara

“…Of these, 29 (70.7%) were still active in care, 7 were tracked [5 (12.2%) lost to program, 2 (4.9%) dead] and 5 patients were not tracked. …”
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A two-tier optimization strategy for feature selection in robust adversarial attack mitigation on internet of things network security by Kashi Sai Prasad, P Udayakumar, E. Laxmi Lydia, Mohammed Altaf Ahmed, Mohamad Khairi Ishak, Faten Khalid Karim, Samih M. Mostafa

“…DL has a considerable reputation in NIDS, owing to its robust ability to identify delicate differences between malicious and normal network activities. …”
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Physical, Textural, Rheological, and Sensory Characteristics of Amaranth-Based Wheat Flour Bread by Sahreen Nasir, Farhana Mehraj Allai, Murtaza Gani, Shaiq Ganaie, Khalid Gul, Aabida Jabeen, Darakshan Majeed

“…AF supplementation increased the moisture (31.06 to 33.24%), ash (0.92 to 1.51%), protein (12.17 to 13.11%), fat (2.16 to 2.77%), and crude fibre content (1.11 to 1.72%) of the bread while the nitrogen-free extract and alkali water retention capacity decreased from 52.58 to 47.65% and 136.00 to 112.02%, respectively. The antioxidant activity evaluated by DPPH, FRAP, and total phenolic content was reduced with increased levels of AF. …”
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Preparing physiotherapists for the future: the development and evaluation of an innovative curriculum by Niki Stolwijk, Anne van Bergen, Evy Jetten, Marjo Maas

“…PACE distinguishes itself from traditional education because of the flexible learning routes, vertical organization in learning communities, absence of pre-defined learning activities and class schedules, and a culture of continuous learning and development. …”
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