Histopathological Finding of Microdamage Accumulation in Atypical Subtrochanteric Femoral Fracture by Yo Watanabe, Naoki Kondo, Tomomi Fukuhara, Norio Imai, Masahiko Yamada, Naoto Endo

“…Cancellous bone, isolated from the right ilium, was autogenously implanted into the fracture site. Fracture healing was promoted using low-intensity pulse ultrasonography. …”
Get full text

Does hydrogen-rich water mitigate MP toxicity in rainbow trout (Oncorhyncus mykiss)? Monitoring with hematology, DNA damage, and apoptosis via ROS/GSH/MDA pathway by Atamanalp Muhammed, Kırıcı Muammer, Köktürk Mine, Kırıcı Mahinur, Alwazeer Duried, Kocaman Esat Mahmut, Ucar Arzu, Parlak Veysel, Özcan Sinan, Alak Gonca

“…In addition, acetylcholinesterase enzyme (AChE) activity, which is important in neurotoxicity pathways in the brain, was determined. …”
Get full text

The influence of contemporary and emerging factors on blood lead concentrations among young males in conflict with the law: a case study from a middle-income country by Thokozani P. Mbonane, Andre Swart, Angela Mathee, Angela Mathee, Nisha Naicker, Nisha Naicker

“…Contemporary and emerging risk factors such as being born outside the country (AOR: 3.10, 95%CI: 1.01–1.88), involvement in illegal mining activities (AOR: 1.36, 95%CI: 1.14–1.91) and staying in a house with peeling paint on the outside (AOR: 2.26, 95%CI: 1.12–4.30) were found to influence blood lead concentration.DiscussionThe study findings show that contemporary (co-existing) and emerging factors influence blood lead concentrations. …”
Get full text

Abnormal dynamic features of cortical microstates for detecting early-stage Parkinson's disease by resting-state electroencephalography: Systematic analysis of the influence of eye... by G. Gimenez-Aparisi, E. Guijarro-Estelles, A. Chornet-Lurbe, D. Cerveró-Albert, Dongmei Hao, Guangfei Li, Y. Ye-Lin

“…Recent evidence has shown that the source-space microstates can characterize distinct functional connectivity patterns but its clinical ability to detect neuropathological changes has not been demonstrated so far. …”
Get full text

Growth of the prefrontal cortical glioblastoma altered cognitive and emotional behaviors via mediating miRNAs and GABA-A receptor signaling pathways in rats by Sepide Nateghi, Ameneh Rezayof, Fatemeh Kouhkan, Ladan Delphi, Yavar Bagheri Davisaraei, Fatemeh Rostami, Fatemeh Tirgar, Houri Sepehri

“…The present study investigated the impact of GABAergic signaling and miRNA expression on glioblastoma multiforme (GBM) growth within the medial prefrontal cortex (mPFC) and its associated cognitive and emotional impairments. …”
Get full text

Enhancing physicochemical, bioactive, and nutritional properties of sweet potatoes: Ultrasonic contact drying with slot jet nozzles compared to hot-air drying and freeze drying by Gulcin Yildiz, Yuan Gao, Junzhou Ding, Si Zhu, Guibing Chen, Hao Feng

“…Notably, SJR + US at 50 °C produced the highest total starch (36.84 g/100 g), total dietary fiber (8.48 g/100 g), total phenolic content (158.19 mg GAE/100 g), total flavonoid content (119.08 mg QE/g), DPPH antioxidant activity (6.44 μmol TE/g), β-carotene (31.98 mg/100 g), and vitamin C (5.27 mg/100 g). …”
Get full text

Prevalence of disability in Iranian older adults in Tehran, Iran: A population-based study by Vahid Rashedi, Mohsen Asadi-Lari, Mahshid Foroughan, Ahmad Delbari, Reza Fadayevatan

“…Conclusion: For older adults, disability directly affects daily functioning by restricting physical and social activities, the ability to maintain self-sufficiency, and ultimately the freedom to live a chosen lifestyle. …”
Get full text

Gastroprotective Effects of Aqueous Extracts of Broccoli Stems on Acute Injury in Rats: A Comprehensive Evaluation of Gastric Function and Inflammatory Responses by Jihye Choi, Yuseong Jang, Hyeon-Gi Paik, Melissa Hyun-Joo Ha, Jungkee Kwon

“…<i>Materials and Methods</i>: The antioxidant properties of BSE were evaluated through DPPH and ABTS radical scavenging activity assays and total polyphenol content analysis. …”
Get full text

Molecular Xenomonitoring (MX) allows real-time surveillance of West Nile and Usutu virus in mosquito populations. by Clément Bigeard, Laura Pezzi, Raphaelle Klitting, Nazli Ayhan, Grégory L'Ambert, Nicolas Gomez, Géraldine Piorkowski, Rayane Amaral, Guillaume André Durand, Agathe M G Colmant, Cynthia Giraud, Katia Ramiara, Camille Migné, Gilda Grard, Thierry Touzet, Stéphan Zientara, Rémi Charrel, Gaëlle Gonzalez, Alexandre Duvignaud, Denis Malvy, Xavier de Lamballerie, Albin Fontaine

“…Both viruses can be transmitted to humans through mosquito bites, which can lead to neuroinvasive and potentially fatal disease. …”
Get full text

Efficient Acquisition of Fully Human Antibody Genes against Self-Proteins by Sorting Single B Cells Stimulated with Vaccines Based on Nitrated T Helper Cell Epitopes by Liangliang Jiang, Tao Jiang, Jianhua Luo, Yanliang Kang, Yue Tong, Xiaoda Song, Xiangdong Gao, Wenbing Yao, Hong Tian

“…NitraTh had enhanced ability to activate CD4+ T cells and can be recognized by CD4+ T cells with different HLA class II haplotypes. …”
Get full text

Identification of cepharanthine as an effective inhibitor of African swine fever virus replication by Chuanxiang Qi, Jiyoung Lee, Yongqiang Zhang, Huan Chen, Jiaxuan Lv, Zhenzhong Wang, Jinming Li, Xiaodong Wu, Yong-Sam Jung, Zhiliang Wang, Yingjuan Qian

“…According to time-of-addition experiments, CEP primarily exerts its antiviral effect during the early stages of ASFV infection, specifically by inhibiting viral entry. …”
Get full text

Clerodendrum volubile Ethanol Leaf Extract: A Potential Antidote to Doxorubicin-Induced Cardiotoxicity in Rats by Olufunke Esan Olorundare, Adejuwon Adewale Adeneye, Akinyele Olubiyi Akinsola, Daniel Ayodele Sanni, Mamoru Koketsu, Hasan Mukhtar

“…Also, CVE profoundly attenuated alterations in the cardiac tissue oxidative stress markers’ activities while improving DOX-associated cardiac histological lesions that were possibly mediated via free radical scavenging and/or antioxidant mechanisms. …”
Get full text

Nepoznato ostvarenje arhitekta Hinka Vichre u Rijeci by Srđan Škunca

“…U spomenutom naselju, međutim, bit će izvedene samo dvije zgrade smanjenih dimenzija, dok će izvorni projekt biti ostvaren samo na navedenoj lokaciji na Kantridi. …”
Get full text

Yeokwisan: Standardised Herbal Formula Enhancing Gastric Mucosal Protection Against Gastric Ulcers in Mice, a Preclinical Study by Yun Mi Lee, Kyuhyung Jo, So Yeon Kim, Chang-Seob Seo, Eunjung Son, Aejin Kim, Dong-Seon Kim

“…<b>Methods</b>: We explored the therapeutic value of YWS and its potential effects on gastritis. Its inhibitory effect on gastric mucosal damage and anti-inflammatory activity in animal models of alcohol- and restraint stress-induced gastritis were also examined. …”
Get full text

Oridonin: A natural terpenoid having the potential to modulate apoptosis and survival signaling in cancer by Abhishek Chauhan, Hemant Joshi, Divya Kandari, Diwakar Aggarwal, Ritu Chauhan, Hardeep Singh Tuli, Arpit Mehrotra, Abhilasha Sood, Ujjawal Sharma, Darin Mansor Mathkor, Shafiul Haque, Naveen Chandra Joshi, Laurent Dufossé

“…Background: Oridonin, a diterpenoid lactone derived from medicinal plants, has drawn considerable attention due to its therapeutic potential, particularly its anticancer properties. …”
Get full text

Cardiac Resynchronization Therapy Reduces Metaboreflex Contribution to the Ventilatory Response in Heart Failure Population by Jérémie Jaussaud, Laurie Aimable, Pierre Bordachar, Pierre Dos Santos, Laurent Barandon, Philippe Ritter, Raymond Roudaut, Hervé Douard

“…We investigated the metaboreflex activation after cardiac resynchronization therapy (CRT). …”
Get full text

Association between P2X7 Receptor Polymorphisms and Bone Status in Mice by Susanne Syberg, Peter Schwarz, Solveig Petersen, Thomas H. Steinberg, Jens-Erik Beck Jensen, Jenni Teilmann, Niklas Rye Jørgensen

“…We found that strains with the P451 allele (BALB/cJ and 129X1/SvJ) had stronger femurs and higher levels of the bone resorption marker C-telopeptide collagen (CTX) compared to C57Bl/6 (B6) and DBA/2J mice. In strains with the 451L allele, pore-formation activity in osteoclasts in vitro was lower after application of ATP. …”
Get full text

Deep proteomics and network pharmacology reveal sex- and age-shared neuropathic pain signatures in mouse dorsal root ganglia by Sabrina Grundtner, Julia R. Sondermann, Feng Xian, Daniel Malzl, Daniel Segelcke, Esther M. Pogatzki-Zahn, Jörg Menche, David Gómez-Varela, Manuela Schmidt

“…Protein network and multidimensional analysis uncovered distinct hubs of sex- and age-shared biological pathways impacted by neuropathic pain, such as neuronal activity and synaptic function, DNA-damage, and neuroimmune interactions. …”
Get full text

Biocontrol Potential of Rhizospheric Bacillus Strains Against <i>Sclerotinia minor</i> Jagger Causing Lettuce Drop by Lihui Xu, Qinghua Shang, Mogens Nicolaisen, Rong Zeng, Shigang Gao, Ping Gao, Zhiwei Song, Fuming Dai, Jingze Zhang

“…Bioactivity experiments showed that Bac20 had higher inhibitory activity against <i>S. minor</i> Jagger than Bac45. …”
Get full text

Patient and public involvement in the design and protocol development for a platform randomised trial to evaluate diagnostic tests to optimise antimicrobial therapy (PROTECT) [vers... by Sammy Ainsworth, Cherry-Ann Waldron, Sarah Jones, Julie Carman, Martina Svobodova, Graham Prestwich, Margaret Ogden, Melanie Gager, Liza Keating

“…Background Our patient and public involvement activities were part of a project aiming to develop a master protocol and National Institute for Health and Care research application for the PROTECT trial aiming to assess the effectiveness, implementation, and efficiency of antimicrobial stewardship interventions, to safely reduce unnecessary antibiotic usage by excluding severe bacterial infection in acutely unwell patients. …”
Get full text