TLR7/8/9 agonists and low-dose cisplatin synergistically promotes tertiary lymphatic structure formation and antitumor immunity by Shuting Wu, Rong Xiang, Yiwei Zhong, Shushu Zhao, Zhiyu Zhang, Zhihua Kou, Shijie Zhang, Yi Zhao, Cheng Zu, Gan Zhao, Yanling Xiao, Sulin Ren, Xiaoming Gao, Bin Wang

“…Abstract In situ vaccination (ISV) triggers antitumor immune responses using the patient’s own cancer antigens, yet limited neoantigen release hampers its efficacy. …”
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Hemodynamic Evaluation of Nonselective β-Blockers in Patients with Cirrhosis and Refractory Ascites by Alberto Ferrarese, Valerie Tikhonoff, Edoardo Casiglia, Paolo Angeli, Silvano Fasolato, Diego Faggian, Alberto Zanetto, Giacomo Germani, Francesco Paolo Russo, Patrizia Burra, Marco Senzolo

“…During two consecutive LVP, while being, respectively, off and on NSBB, cardiac output (CO), systemic vascular resistances (SVR), peripheral vascular resistances (PVR), and plasma renin activity (PRA) were noninvasively assessed. Results. …”
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Source attribution, health risk analysis, and policy implications of PAHs and NPAHs in PM $$_{10}$$ in Northern Mexico by Lucy T. González, Ilse María Hernández-Romero, Alberto Mendoza, Aldo I. Ramirez, Yasmany Mancilla, Boris Kharissov, Michael Pérez-Rodríguez, Juan Manuel Alfaro Barbosa, Daniel López Serna, Oxana Kharissova, Andrea Nucamendi, Jesús Abraham Díaz Paéz, Francisco E. Longoria

“…Source apportionment using diagnostic ratios (DRs) and principal component analysis (PCA) indicated that biomass burning, vehicular emissions, and industrial activities were the primary sources of MMA. At the same time, CHI and CDJ were influenced more by industrial and diesel emissions. …”
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Human adenovirus species B knob proteins as immunogens for inducing cross-neutralizing antibody responses by Zhenwei Liu, Yuting Xian, Jixian Lan, Zhichao Zhou, Xiao Li, Rong Zhou, Dehui Chen, Xingui Tian

“…In addition, mouse antisera raised against the knob proteins exhibited cross-neutralizing activity against original species B members. Furthermore, immunization with a mix of HAdV-3, 7, and 55 knob proteins protected Chinese tree shrews against an experimental HAdV challenge. …”
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High Catalytic Selectivity of Electron/Proton Dual‐Conductive Sulfonated Polyaniline Micropore Encased IrO2 Electrocatalyst by Screening Effect for Oxygen Evolution of Seawater Ele... by Yuhan Shen, Shengqiu Zhao, Fanglin Wu, Hao Zhang, Liyan Zhu, Mingjuan Wu, Tian Tian, Haolin Tang

“…Abstract Acidic seawater electrolysis offers significant advantages in high efficiency and sustainable hydrogen production. However, in situ electrolysis of acidic seawater remains a challenge. …”
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Noninvasive Immunotyping and Immunotherapy Monitoring of Lung Cancers via Nuclear Imaging of LAG‐3 and PD‐L1 by Lishu Zhao, Jianxian Ge, Ruru Zhang, Hao Wang, Xinyue Liu, Kandi Xu, Yujin Liu, Wencheng Zhao, Wengang Zhang, Li Ye, Zhimin Chen, Jianfeng Zeng, Yayi He, Mingyuan Gao

“…Abstract Immunotherapy has significantly improved cancer patient survival, while its efficacy remains limited due to the reliance on a single marker like PD‐L1 as well as its spatiotemporal heterogeneity. …”
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Saponin content in medicinal plants in response to application of organic and inorganic fertilizers: a meta-analysis by Junyan Lv, Junyan Lv, Shouzan Liu, Shouzan Liu, Chunli Hu, Lan Ding, Hongzhen Wang, Hongzhen Wang, Xin Li, Feng Yang, Feng Yang, Qiong Shen, Qiong Shen, Hongbin Zhang, Hongbin Zhang, Guobiao Ma, Guobiao Ma, Shaobo Zhang, Yan Bai, Yan Bai

“…However, systematic investigations on the influence of various fertilizers on the concentration of active compounds in saponin-containing medicinal plants remain insufficient. …”
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Data mining and safety analysis of voriconazole in patients with a hematological malignant tumor based on the FAERS database: differences between children and adults by Hao Li, Hao Li, Manxue Jiang, Manxue Jiang, Xiaona Pan, Lingti Kong, Lingti Kong, Lingti Kong

“…Then, they were classified using the preferred terminology (PT) and system organ category (SOC) in the Medical Dictionary for Regulatory Activities. Data mining was done using reporting odds ratio (ROR), proportional reporting ratio (PRR), Bayesian confidence propagation neural network (BCPNN), and multi-item gamma Poisson shrinker (MGPS).ResultsA total of 605 ADEs were included: 116 (19.17%) in children and 489 (80.83%) in adults. …”
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Florid cemento osseous dysplasia and dentygerous cyst in a patient with apert syndrome: A case report by Nazlıcan Paslı, Fatma Nihan Aksakallı, Ender İdman, M. Oğuz Borahan, Emrah Canbazoğlu, Hasan Garip, Şebnem Erçalık Yalçınkaya

“…Oral manifestations of Apert syndrome usually represents bifid uvula, malposition of the teeth, severe open bite, tooth decay and periodontal diseases. Fluorid cemento-osseous dysplasia is usually asymptomatic slow-growing non-neoplastic fibro-osseous lesions. …”
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Effect of the adhesive added of copper applied with electric current on the ceramic/resin cement bond by Gabriel Augusto Silveira Sousa, Marcos Henrique Ramos da Silva, Lourenço Correr-Sobrinho, Rafael Pino Vitti, Evandro Piva, Rafael Leonardo Xediek Consani

“…IPS e.max Press ceramic discs included in rigid polyvinyl chloride tubes with chemically activated acrylic resin were divided into four groups (n = 10): RX + UA (silane + universal adhesive); RX + UA + EC (silane + universal adhesive + electrical current); RX + EA (silane + experimental adhesive); and RX + EA + EC (silane + experimental adhesive + electrical current). …”
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Teachers’ responses to racism and racist bullying in Dutch primary schools by Karen M. A. Sieben-Aduful, Roy A. Willems, Trijntje Völlink, Nico van der Wiel, Maria Sapouna, Pieter de Bruijn, Gemma Blok, Gemma Blok, Arjan E. R. Bos, Arjan E. R. Bos, Giel van Lankveld

“…Further, the results implicate that a pro-active approach can stimulate teachers to critically reflect on their own racial identity, and on school methods, teaching resources and policies concerning racism.…”
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HBV and HBsAg strongly reshape the phenotype, function, and metabolism of DCs according to patients’ clinical stage by Lucile Dumolard, Theophile Gerster, Florent Chuffart, Thomas Decaens, Marie-Noelle Hilleret, Sylvie Larrat, Philippe Saas, Evelyne Jouvin-Marche, David Durantel, Patrice N. Marche, Zuzana Macek Jilkova, Caroline Aspord

“…Strikingly, we observed that HBV-exposed DCs secrete high levels of CX3CL1 (fractalkine), a chemokine responsible for attracting antiviral effectors to the site of infection. HBsAg exposure favored DC activation while drastically altering TRAIL expression in response to toll-like receptor ligand and increasing the secretion of cytokines/chemokines involved in immune tolerance. …”
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Exploring Prevalence and Sociodemographic Factors Associated With Smoking Among Malaysian Adults: A Cross‐ Sectional Study by Mohd Hasni Ja'afar, Rosnah Ismail, Zaleha Md Isa, Azmi Mohd Tamil, Noor Hassim Ismail, Nafiza Mat Nasir, Nik Munirah Nasir, Nurul Hafiza Ab Razak, Najihah Zainol Abidin, Andrew Mente, Khairul Hazdi Yusof

“…The sociodemographic factors significantly associated with active smoking status were being a younger adult (adjusted odds ratio [AOR] = 1.26, 95% CI: 1.06–1.50), being male (AOR = 24.16, 95% CI: 20.58–28.36), being Malay (AOR = 1.72, 95% CI: 1.49–1.98), being a blue‐collar worker (AOR = 1.75, 95% CI: 1.48–2.06), having no formal education (AOR = 1.99, 95% CI: 1.56–2.53), being unmarried (AOR = 1.22, 95% CI: 1.02–1.48) and being of low socioeconomic status (AOR = 1.45, 95% CI: 1.14–1.84). …”
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Emerging contaminant removal using eco-friendly zinc ferrite nanoparticles: Sunlight-driven degradation of tetracycline by Ramesh Vinayagam, Syonaa Batra, Gokulakrishnan Murugesan, Louella Concepta Goveas, Thivaharan Varadavenkatesan, Ashton Menezes, Raja Selvaraj

“…Even after five cycles, the material retained over 73 % degradation efficiency, showcasing its durability. This work highlights the potential of eco-friendly ZnFe2O4 nanoparticles as a sustainable and efficient solution for mitigating emerging contaminants in wastewater, contributing to environmental remediation efforts.…”
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Combination Treatments of Plasma Exchange and Umbilical Cord-Derived Mesenchymal Stem Cell Transplantation for Patients with Hepatitis B Virus-Related Acute-on-Chronic Liver Failur... by Wen-xiong Xu, Hong-liang He, Shun-wen Pan, Yuan-li Chen, Mei-ling Zhang, Shu Zhu, Zhi-liang Gao, Liang Peng, Jian-guo Li

“…The multivariate logistic regression analysis demonstrated that hemoglobin, prothrombin activity, and MELD (model for end-stage liver disease) score were the independent factors associated with the unfavorable outcome (all P<0.05). …”
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Microbiota, parasitic infections and their relationship with nutritional status and neurocognitive functioning in children from Ecuador—Proyecto Guagua: research protocol for a cro... by Sandra Victoria Abril-Ulloa, Tannia Valeria Carpio-Arias, Renata Alejandra Alvarado-Barba, Cristina Gabriela Ríos-Romero, Pamela Vinueza-Veloz, Sueny Paloma Lima-dos-Santos, Sueny Paloma Lima-dos-Santos, Igor Eduardo Astudillo-Skliarova, Igor Eduardo Astudillo-Skliarova, Ruth Irene Arias-Gutiérrez, Manuel Pérez-Quintana, Henk-Jan Boele, Henk-Jan Boele, Henk-Jan Boele, María Fernanda Vinueza-Veloz

“…Enrolled children undergo comprehensive evaluations assessing nutritional status, body composition, motor learning, social skills, cognitive ability, sleep habits, and physical activity. Caretakers and school teachers are interviewed regarding hygiene, eating habits, and food handling. …”
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Analysis of 42 Years of Cosmic Ray Measurements by the Neutron Monitor at Lomnický štít Observatory by Imre Kisvárdai, Filip Štempel, Lukáš Randuška, Šimon Mackovjak, Ronald Langer, Igor Strhárský, Ján Kubančák

“…Our investigation is centered on the relationships among the solar radio flux, geomagnetic field activity, and cosmic ray flux, as observed by the Neutron Monitor at the Lomnický štít Observatory in Slovakia. …”
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Stem Cell Therapy for the Treatment of Amyotrophic Lateral Sclerosis: Comparison of the Efficacy of Mesenchymal Stem Cells, Neural Stem Cells, and Induced Pluripotent Stem Cells by Lauren Frawley, Noam Tomer Taylor, Olivia Sivills, Ella McPhillamy, Timothy Duy To, Yibo Wu, Beek Yoke Chin, Chiew Yen Wong

“…Conclusions: This research is significant for advancing ALS treatment beyond symptomatic relief and modest survival extensions to actively modifying disease progression and improving patient outcomes. …”
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Effect of diabetes mellitus on levels of insulin-like growth factors and their carrier proteins in Guerin’s carcinoma and it’s perifocal tissue in rats by E. M. Frantsiyants, V. A. Bandovkina, I. V. Kaplieva, E. I. Surikova, I. V. Neskubina, Yu. A. Pogorelova, N. D. Cheryarina, P. S. Kachesova, L. A. Nemashkalova

“…DM in females upregulated levels of glucose both in the tumor and in perifocal tissues by 1.8 (p &lt; 0.05) and 8.1 times, respectively, but caused opposite changes in IGF-I - it's increase by 6.3 times in the tumor and decrease by 3.2 times in the perifocal area; as a result, such tumors with small primary nodes were more "aggressive" and actively metastasized. In males, induced DM downregulated levels of glucose, IGF-II and IGFBP2 in the carcinoma by 8.4, 3.1 and 1.7 (p &lt; 0.05) times, respectively, and increased levels of IGF-I and IGFBP2 by 1.4 and 1.3 times (p &lt; 0.05) in the perifocal area without changing glucose levels; as a result, tumor volumes exceeded the values in the standard growth, without metastasizing into visceral organs.Conclusion. …”
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Structure of a Sulfated Capsular Polysaccharide from the Marine Bacterium <i>Cobetia marina</i> KMM 1449 and a Genomic Insight into Its Biosynthesis by Maxim S. Kokoulin, Yulia V. Savicheva, Alina P. Filshtein, Ludmila A. Romanenko, Marina P. Isaeva

“…A number of studies indicate significant biological properties of individual sulfated polysaccharides, such as antiproliferative activity, which makes them a promising area for further research. …”
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