Ibuprofen reduces inflammation, necroptosis and protects photoreceptors from light-induced retinal degeneration by Ping-Wu Zhang, Zi-He Wan, Weifeng Li, Abhishek Vats, Kunal Mehta, Laura Fan, Lingli Zhou, Sean Li, Gloria Li, Casey J. Keuthan, Cynthia Berlinicke, Cheng Qian, Noriko Esumi, Elia J Duh, Donald J. Zack

“…Expression of key necroptosis genes, including Ripk3 and Mlkl, were upregulated in LD vehicle-treated mice, but dramatically reduced to near no LD levels in LD IBU-treated mice. Microglia activation and MLKL protein upregulation were observed primarily in photoreceptors 12 h after LD, as assessed by immunohistochemistry. …”
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Implementation strategies: lessons learned during an e-learning intervention to improve dietary behaviors and feeding practices in early childhood education and care by Henrik Lian, Nina Cecilie Øverby, Frøydis Nordgård Vik, Anine Christine Medin, Natalie Garzon Osorio, Christine Helle, Tormod Bjørkkjær, Penelope Love, Harry Rutter, Mary Elizabeth Barker, Elisabet Rudjord Hillesund, Sissel Heidi Helland

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Reactive agility training to prevent frailty in older adults – a randomized controlled trial. by Eric Lichtenstein, Martin Keller, Ralf Roth, Sebastian Ludyga, Oliver Faude

“…European Review of Aging and Physical Activity, 20(1), 21. https://doi.org/10.1186/s11556-023-00331-6 …”
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Les techniques de construction du second forum de Bavay (Nord) : utilisation, origine et datation des matériaux en terre cuite by Xavier Deru, Christine Louvion

“…The characterization of the materials in terracotta and their incorporation in the different walls enabled us to estimate a volume of between 2,000 and 2,750 m3 (3,600-4,950 t) and a volume of tiles of 246 m3 (440 t).The supply of terracotta from a relatively distant region raises questions, as there were nearer workshops in activity. On account of the considerable quantity of terracotta required, multiple suppliers were called upon, spread over the Meuse Valley, which led to a relative heterogeneity of materials, but reduced waiting time in line with the needs of the site. …”
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The use of immunostimulant from phycocyanin of Spirulina platensis to control motile aeromonad septicaemia (MAS) disease in common carp Cyprinus carpio by Muthahharah Muchtar, Sukenda Sukenda, Sri Nuryati, Dendi Hidayatullah

“…Total erythrocytes, hemoglobin, total leucocytes, phagocytic activity, and respiratory burst showed higher results than control treatment on all treated fish. …”
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Acceptability and Implementation Challenges of Benzathine Penicillin G Secondary Prophylaxis for Rheumatic Heart Disease in Ethiopia: A Qualitative Study by Eshetie Melese Birru, Kevin T. Batty, Laurens Manning, Stephanie L. Enkel, Brioni R. Moore

“…Highlights: • Key barriers included (a) resistance from healthcare providers to administer benzathine penicillin G (BPG) due to their concerns about injection-related severe adverse events, and potential repercussions should an event occur, (b) poor community and healthcare provider awareness of the disease and its treatment, (c) lack of resources to manage adverse events, and (d) injection pain. • Key enablers included (a) perceived superior treatment benefits of BPG and (b) co-administration of lidocaine/analgesics to reduce injection pain. • Recommendations to address identified challenges include (a) improved training/education on RHD diagnosis, disease progression, and treatment, (b) improved access to supportive resources, (c) active adverse reaction monitoring and reporting, and (d) encouraging the provision/access of globally subsidized BPG suspension formulations in pre-filled syringes.…”
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Waste marble sludge and calcined clay brick powders in conventional cement farina production for cleaner built environment by Mehmet Serkan Kırgız, Jamal Khatib, Andre Gustavo de Sousa Galdino, Said Kenai, Ahmed Ashteyat, Raul D.S.G. Campilho, Roberto Alonso Gonzalez Lezcano, Gideon Olukunle Bamigboye, N. Nagaprasad, Krishnaraj Ramaswamy

“…Besides, to evaluate pozzolanic activity, the construction lime was mixed with the marble and brick wastes. …”
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The effect of core stabilization exercises and shock wave therapy in patients with radiculopathy by J. Bubelis

“…Comparison between the two groups suggests that the cycle of application of spinal stabilization exercise program and shock wave therapy has a greater positive effect on pain, muscle endurance, dynamic stability and its management. …”
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Effect of colloidal particle size on physicochemical properties and aggregation behaviors of two alkaline soils by Y. Yan, X. Zhang, C. Xu, C. Xu, J. Liu, F. Hu, F. Hu, Z. Geng, Z. Geng

“…<p>Colloidal particles are the most active soil components, and they vary in elemental composition and environmental behaviors with the particle size due to the heterogeneous nature of natural soils. …”
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Pengukuran Kapabilitas Tata Kelola TI Sistem Informasi Tiras dan Transaksi Bahan Ajar Universitas Terbuka Menggunakan Cobit 5 by Denisha Trihapningsari, Dewi Agushinta R., Lintang Yuniar Banowosari

“… Layanan bahan ajar Universitas Terbuka (UT) menerapkan Sistem Informasi Tiras dan Transaksi Bahan Ajar (SITTA) yang dalam prosesnya ditemui masalah terkait operasional dan optimalisasi Teknologi Informasi. Oleh sebab itu evaluasi perlu dilakukan untuk mengetahui sejauh mana sistem telah memenuhi kebutuhan organisasi tata kelola TI. …”
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Formation of forest mensuration indicators of Pseudotsuga menziesii (Mirb.) Franco in artificial plantations of the western region of Ukraine by Iurii Debryniuk, Stepan Myklush, Yuriy Myklush

“…The documented age-related trends in Pseudotsuga menziesii measurement parameters within artificial plantations, combined with the optimization of forestry activities, will facilitate informed decision-making and allow for making rational decisions and determining priority directions for management strategies for Pseudotsuga plantations in fresh fertile site types in the western region of Ukraine.…”
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Inflammatory Gene Signature Identified by Machine Algorithms Reveals Novel Biomarkers of Coronary Artery Disease by Liu X, Zhang Y, Wang Y, Xu Y, Xia W, Liu R, Xu S

“…Then, the receiver operating characteristic (ROC) curves were plotted for each DIRG, and those with an area under the curve (AUC) greater than 0.9 were selected for subsequent analysis. …”
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Variations in vitamin D status among Chinese children aged 1–6 years during the COVID-19 pandemic by Yongfeng Qiao, Xiaoqin Wang, Yanfen Ma, Jian Hu

“…Closed-off management brought about by the COVID-19 pandemic has drastically impacted outdoor activities and sunlight exposure, however, whether it indirectly further exacerbated the vitamin D deficiency has not been largely investigated, especially among children in China. …”
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Association of the Ratio of Triglycerides to High-Density Lipoprotein Cholesterol Levels with the Risk of Type 2 Diabetes: A Retrospective Cohort Study in Beijing by Hongzhou Liu, Shuangtong Yan, Gang Chen, Bing Li, Ling Zhao, Yajing Wang, Xiaodong Hu, Xiaomeng Jia, Jingtao Dou, Yiming Mu, Junping Wen, Zhaohui Lyu

“…After adjusting for age, sex, body mass index, smoking status, alcohol intake, low-density lipoprotein cholesterol level, strenuous activity, education level, family histories of T2DM and tumors, and the presence of hypertension, tumor, stroke, and coronary heart disease, we showed that TG/HDL-C was positively associated with the incidence of T2DM at the 4-year follow-up (OR=1.49, 95%CI=1.26–1.78). …”
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Acid-Unlocked Two-Layer Ca-Loaded Nanoplatform to Interfere With Mitochondria for Synergistic Tumor Therapy by Zheng Y, Williams GR, Hu R, Tong S, Xu J, Wang T, Zhang Y, Wu J, Li F, Cai Y, Zhu LM

“…Robust in vitro and in vivo data demonstrate the efficacy of this approach and CaO2@ZIF8:CUR@PAA as an anticancer platform, paving the way for nanomaterials in immune-triggered cancer therapy.Highlights: - A new calcium accumulation nanoplatform plays a role in activate antitumor immunity.- Double-locked structure slows down the premature decomposition of CaO2.- The platform allows Ca2+ and H2O2 to accumulate in tumor cells.- This leads to mitochondrial dysfunction, apoptosis, and M1 macrophage polarization.- Potent anti-tumor effects are seen both in vitro and in vivo.Keywords: Calcium ion load, controlled-release nanomaterials, two-layer protective shell, pH responsive drug release, reactive oxygen species, anti-cancer…”
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Gambaran Hitung Jenis Leukosit pada Pasien Penyakit Paru Obstruktif Kronik yang Dirawat di RSUP Dr. M. Djamil Padang by Revi Sofiana Martantya, Ellyza Nasrul, Masrul Basyar

“…Cigarette smoke, air pollution, and recurrent infections in the respiratory tract can activates alveolar macrophages to release inflammatory mediators that stimulate granulocytic and monocytic progenitors in the bone marrow that can affect leukocyte counts in peripheral blood. …”
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Biodiversity Patterns of Rocky Coastal and Human-Made Structures in Gheshm Shorelines; Role of Slope and Tidal Levels Characteristics in Determining Patterns of Biodiversity by Marzieh Razaghi, Ali Nasrolahi, Ehsan Kamrani, Mohammad Sharif Ranjbar, Amir Vazirizadeh

“…Introduction: The coastal landscapes are constantly changing due to the increasing demand for structures aimed at economic, residential, and tourism activities. Human-made constructions such as breakwaters, piers, and seawalls have become characteristic features alongside shallow habitats in intertidal and subtidal zones. …”
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Characterization of a novel covS SNP identified in Australian group A Streptococcus isolates derived from the M1UK lineage by Johanna Richter, Amanda J. Cork, Yvette Ong, Nadia Keller, Andrew J. Hayes, Mark A. Schembri, Amy V. Jennison, Mark R. Davies, Kate Schroder, Mark J. Walker, Stephan Brouwer

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L’aqueduc du Gier à Lyon : la complexité de la protection au titre des monuments historiques by Josiane Boulon

“…He then began to travel and draft reports about the country’s ancient buildings. This active approach led to the presentation in 1840 of the first list of ancient buildings requiring preservation. …”
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Application of care bundles based on the concept of enhanced recovery after surgery in perioperative nursing of patients undergoing laparoscopic cholecystectomy (基于加速康复外科理念的集束化干预在腹... by FANG Shuheng (房树恒), ZHU Hengmei (朱恒美), DONG Zhitao (董志涛), HE Dandan (贺丹丹)

“…The time to first postoperative exhaustion, time to off-bed activities and hospital stays in the observation group were shorter than those in the control group (P＜0. 05). …”
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