CircSPG21 ameliorates oxidative stress-induced senescence in nucleus pulposus-derived mesenchymal stem cells and mitigates intervertebral disc degeneration through the miR-217/SIRT1 axis and mitophagy by Yongbo Zhang, Sheng Yang, Xuan You, Zhengguang Li, Liuyang chen, Rui Dai, Hua Sun, Liang Zhang

“…CircSPG21 also ameliorated disc degeneration in the IVDD rat model, highlighting its potential as a therapeutic target. …”
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Iron triggers TvPI4P5K proteostasis and Arf-mediated cell membrane trafficking to regulate PIP2 signaling crucial for multiple pathogenic activities of the parasitic protozoan Trichomonas vaginalis by Kuan-Yi Wu, Yen-Ju Chen, Shu-Fan Lin, Hong-Ming Hsu

“…This study further demonstrated that iron transiently regulated T. vaginalis phosphatidylinositol-4-phosphate 5-kinase (TvPI4P5K) proteostasis and its complex formation with an active ADP ribosylation factor TvArf220, facilitating co-trafficking to the plasma membrane, crucial for PIP2 production. …”
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To remove or to replace traditional electronic games? A crossover randomised controlled trial on the impact of removing or replacing home access to electronic games on physical activity and sedentary behaviour in children aged 10–12 years by Anne J Smith, Leon M Straker, Rebecca A Abbott

“…Objective To evaluate the impact of (1) the removal of home access to traditional electronic games or (2) their replacement with active input electronic games, on daily physical activity and sedentary behaviour in children aged 10–12 years.Design Crossover randomised controlled trial, over 6 months.Setting Family homes in metropolitan Perth, Australia from 2007 to 2010.Participants 10-year-old to 12-year-old children were recruited through school and community media. …”
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A phase 1b clinical trial to determine the safety, tolerability and immunogenicity of simian adenovirus and poxvirus vectored vaccines against Mycobacterium avium complex subspecies in patients with active Crohn’s diseaseResearch in context by Jeremy Sanderson, Jeremy Aboagye, Rebecca Makinson, Katerina Rapi, Samuel Provstgaard-Morys, Lisa Stockdale, Alison Lawrie, Isabelle Lanigan, Nishat Halim, Abdel Douiri, Emily Greenlay, Rayka Malek, Emma Gray, Lindsey West, Fatima El Oulidi, Paul Ian Cross, Michael Stallibrass, Sarah C. Gilbert, Adrian V.S. Hill, Katie J. Ewer

“…The majority of solicited AEs were graded as mild (149/196; 76%, 95% CI 69%–82%) or moderate (45/196; 23%, 95% CI 17%–29%). …”
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Minimization of the Bacillus subtilis divisome suggests FtsZ and SepF can form an active Z-ring, and reveals the amino acid transporter BraB as a new cell division influencing factor. by Ilkay Celik Gulsoy, Terrens N V Saaki, Michaela Wenzel, Simon Syvertsson, Taku Morimoto, Tjalling K Siersma, Leendert W Hamoen

“…In this study, we tried to find the minimal set of proteins that is required to establish an active Z-ring in the model bacterium Bacillus subtilis. …”
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Studies about the Active Pessimist. - Rec.: Opacki Z. Między uniwersalizmem a partykularyzmem.... by Algis Povilas Kasperavičius

“… Studies about the Active Pessimist. - Rec.: Opacki Z. Między uniwersalizmem a partykularyzmem. …”
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Molecular docking and dynamics studies to identify novel active compounds targeting potential breast cancer receptor proteins from an indigenous herb Euphorbia thymifolia Linn [version 3; peer review: 2 approved] by ShamaPrasada K, Reshma Kumarchandra, Vasavi Kumblekar, K Sreedhara Ranganath Pai, Suman Manandhar, Sharada Rai, Rajeshwari Shastry

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Modulatory effects of selenium nanoparticles on gut microbiota and metabolites of juvenile Nile tilapia (Oreochromis niloticus) by microbiome-metabolomic analysis by Jing Ni, Lirong Ren, Ying Liang, Ying Ma, Hejian Xiong

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Red dragon fruit (Hylocereus polyrhizus), a superfruit rich in betacyanins pigments with antioxidative potential for hepatoprotection: A review by Teck Wei Lim, Renee Lay Hong Lim, Liew Phing Pui, Chin Ping Tan, Chun Wai Ho

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Optical hausdorff quantum energy of spherical magnetic particles by Talat Körpinar, Zeliha Körpinar, Hatice özdemir, ALi Akgül, Murad Khan Hassani

Subjects: “…Spherical magnetic curve…”
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The impact of smartphone addiction on exercise patterns: a systematic review by Siti Kotijah, Ah Yusuf, Rizki Fitryasari P K, Ronal Surya Aditya, Binarti Dwi Wahyuni, Reem Iafi AlMutairi, Fitriana Kurniasari Solikhah, Muhammad Putra Ramadhan

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The Impact of Bar-induced Noncircular Motions on the Measurement of Galactic Rotation Curves by Jie Liu, Zhi Li, Juntai Shen

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Impacts of pseudomonas fluorescent bacterial fertilizer addition on the soil environment and fruit yield under water stress in greenhouse grape by Yanting Gao, Hongjuan Zhang, Rui Zhang, Zhen Huang, Changyu Yang

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TOWARDS IMPLEMENTATION OF INNOVATIVE METHODOLOGIES IN CONSTRUCTION ENGINEERING IN CHILE. A CASE STUDY by PEDRO MUÑOZ, VIVIANA LETELIER, LUMINITA BIBIRE, LUIS MUÑOZ

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New Forms of the Open Newton-Cotes-Type Inequalities for a Family of the Quantum Differentiable Convex Functions by Jarunee Soontharanon, Muhammad Ali, Shahram Rezapour, Muhammad Toseef, Thanin Sitthiwirattham

Subjects: “…open newton-cotes formulas…”
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In vitro study on the inhibitory effect of various essential oils against murine coronavirus mouse hepatitis virus A-59 replication by Karelle Contant, Shiv Shankar, Monique Lacroix

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ROITP: Road Obstacle-Involved Trajectory Planner for Autonomous Trucks by Yechen Qin, Yiwei Huang, Wenhao Yu, Hong Wang

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Recurrent pregnancy loss: etiology, pathophysiology, diagnosis and treatment by Zlatko Kirovakov, Elitsa H. Gyokova, Nadezhda H. Hinkova, Emiliana I. Konova

Subjects: “…Plasminogen activator inhibitor (PAI) 4G/5G…”
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In vitro efficacy of plant growth-promoting rhizobacteria isolated from ginger (Zingiber officinale) rhizosphere for biological control of plant pathogens by Ruth Meike Jayanti, Sabrina Ayu Kristianingrum, Andree Wijaya Setiawan

Subjects: “…in vitro antagonistic activity test…”
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