Diabetes Technology: Markers, Monitoring, Assessment, and Control of Blood Glucose Fluctuations in Diabetes by Boris P. Kovatchev

“…Technology integrating CGM with insulin pumps is now available, opening the field for automated closed-loop control, known as the artificial pancreas. …”
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The Effects of Glucose Fluctuation on the Severity of Coronary Artery Disease in Type 2 Diabetes Mellitus by Xingguang Zhang, Xiuping Xu, Xiumin Jiao, Jinxiao Wu, Shujing Zhou, Xiaofeng Lv

“…The SYNTAX scores were collected in group C. CGMS for 72 h was applied on all the subjects. The indexes such as MBG and the LAGE were calculated. …”
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Arginine–NO pathway modulated energy metabolism in the hepatopancreas and muscle of female Litopenaeus vannamei by Haitao Fan, Xin Zhang, Yanan Yin, Lefei Jiao

“…The findings showed that the levels of nos, cgmp, ampk (a, b, c), genes involved in glucose metabolism, lipid metabolism and amino acid metabolism were inhibited. …”
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Impact of Dietary Intake and Cardiorespiratory Fitness on Glycemic Variability in Adolescents: An Observational Study by Mingliang Ge, Stephanie R Lebby, Shivani Chowkwale, Caleb Harrison, Grace M Palmer, Keith J Loud, Diane Gilbert-Diamond, Mary Ellen Vajravelu, Jennifer L Meijer

“…Results: Participant feasibility demonstrated that 90% completed CGM data (n = 27), 87% ≥7 d of CGM data (n = 26), 97% attempted OGTT (n = 29), and 93% completed ≥3 dietary recalls (n = 28). …”
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FOXE1 Mutation Screening in a Case with Cleft Lip, Hypothyroidism, and Thyroid Carcinoma: A New Syndrome? by Hugo Mendieta-Zerón, Angélica Jiménez-Rosales, Carlos Jhovani Pérez-Amado, Silvia Jiménez-Morales

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Sexual Differences in response to Mid- or Low-Premixed Insulin Analogue in Patients with Type 2 Diabetes by Bing-li Liu, Xiao-mei Liu, Yi-fei Ren, Yi-Xuan Sun, Meng-hui Luo, Lei Ye, Jian-hua Ma, Feng-fei Li

“…A 4-day continuous glucose monitoring (CGM) was performed during the cross-over period. …”
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Continuous Glucose Monitoring in Newly Diagnosed Type 2 Diabetes Patients Reveals a Potential Risk of Hypoglycemia in Older Men by Feng-fei Li, Bing-li Liu, Hong-hong Zhu, Ting Li, Wen-li Zhang, Xiao-fei Su, Jin-dan Wu, Xue-qin Wang, Ning Xu, Wei-Nan Yu, Qun Yuan, Guan-cheng Qi, Lei Ye, Kok-Onn Lee, Jian-hua Ma

“…We performed continuous glucose monitoring (CGM) to define the features of patients with newly diagnosed type 2 diabetes (T2D) before and after Continuous Subcutaneous Insulin Infusion (CSII) therapy. …”
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PPARα-Independent Arterial Smooth Muscle Relaxant Effects of PPARα Agonists by Neerupma Silswal, Nikhil K. Parelkar, Michael J. Wacker, Mostafa Badr, Jon Andresen

“…In aortas, GW7647 and WY14643 elevated cGMP levels by stimulating soluble guanylyl cyclase (sGC), and inhibition of sGC with ODQ blunted relaxations to PPARα agonists. …”
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Modulation of Second Messenger Signaling in the Brain Through PDE4 and PDE5 Inhibition: Therapeutic Implications for Neurological Disorders by Min Kyu Park, Hyun Wook Yang, Seo Young Woo, Dong Yeon Kim, Dae-Soon Son, Bo Young Choi, Sang Won Suh

“…Among the 11 PDE subtypes, PDE4 and PDE5 are particularly significant due to their regulation of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) signaling, respectively, which are vital for learning, memory, and neuroprotection. …”
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A Novel Role for Brain Natriuretic Peptide: Inhibition of IL-1β Secretion via Downregulation of NF-kB/Erk 1/2 and NALP3/ASC/Caspase-1 Activation in Human THP-1 Monocyte by Letizia Mezzasoma, Cinzia Antognelli, Vincenzo Nicola Talesa

“…Here, we newly demonstrated that, in human THP-1 monocytes, LPS/ATP-induced IL-1β secretion is strongly inhibited by BNP/NPR-1/cGMP axis at all the molecular mechanisms that tightly control its production and release, NF-kB, ERK 1/2, and all the elements of NALP3/ASC/Caspase-1 inflammasome cascade, and that NALP3 inflammasome inhibition is directly related to BNP deregulatory effect on NF-kB/ERK 1/2 activation. …”
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Leveraging Next-Generation Sequencing Application from Identity to Purity Profiling of Nucleic Acid-Based Products by Rucha Wadapurkar, Swarda Deo, Renuka Khanzode, Ajay Singh

“…Perhaps NGS adaptation under cGMP compliance needs to be deliberated with the regulatory bodies, especially focusing on the methods qualification and validation part, starting from the sample collection, NGS library preparation, NGS run, and its data analysis pipeline.…”
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Effects of Fermented Soybean Meal Substituting Plant Protein and Fish Meal on Growth, Flesh Quality, and Intestinal Microbiota of Largemouth Bass (Micropterus salmoides) by Beibei Guo, Lingling Huang, Xiaoqin Li, Yunfeng Chen, Tianyu Huang, Lizhou Ma, Xiangjun Leng

“…This study investigated the effects of replacing soybean meal (SM), corn gluten meal (CGM), and fish meal (FM) with fermented soybean meal (FSM) on growth performance, flesh quality, and intestinal microbiota of largemouth bass. …”
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Real-World Life Analysis of a Continuous Glucose Monitoring and Smart Insulin Pen System in Type 1 Diabetes: A Cohort Study by Paola Pantanetti, Giovanni Cangelosi, Sara Morales Palomares, Gaetano Ferrara, Federico Biondini, Stefano Mancin, Gabriele Caggianelli, Mauro Parozzi, Marco Sguanci, Fabio Petrelli

“…Glycemic parameters were monitored using CGM data and analyzed with descriptive statistics, including mean, standard deviation (SD), and interquartile range (IQR). …”
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Toxicological landscape of Fuzi: a comprehensive study on the spatial distribution of toxicants and regional neurotoxicity variability in zebrafish by Xiaoqi Pan, Xiaoqi Pan, Tianyu Liang, Han Feng, Weiying Liu, Qiaoxin Mou, Xiaoyu Yan

“…RNA sequencing analysis further indicated that the amino acid metabolism, ErbB, cGMP-PKG, and p53 signaling pathways-regulated by changes in the expression of Glub, Mao, GAB1, PRKG1B, PSEN2, and BAXα genes were disrupted to varying extents by Fuzi from different origins. …”
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Accuracy of Freestyle Libre continuous glucose monitoring system in critically ill patients after cardiac surgery by Junjun Gu, Zhimin Zhao, Haiyan Li, Bailing Li, Si Chen, Yingdan Cao, Ning Li, Xiaoying Lu

“…Freestyle Libre Continuous glucose monitor (CGM) is an interstitial glucose monitoring system, which has been proven to be stable and accurate in various disease. …”
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Study protocol of a multicentre, randomised, controlled trial evaluating the effectiveness of probiotic and peanut oral immunotherapy (PPOIT) in inducing desensitisation or toleran... by Michael O’Sullivan, Michael S Gold, Francesca Orsini, Adriana Chebar Lozinsky, Paxton Loke, Susan L. Prescott, Patrick Quinn, Audrey DunnGalvin, Mimi LK Tang, Anne-Louise Ponsoby, Ee Lyn Su, Marnie Robinson, Dean Tey, Kuang-Chih Hsiao, Molly O’Sullivan, Christine Axelrad, Sigrid Pitkin, Jessica Metcalfe, Susan Fahy-Scheer, Thalayasingam Meera, Jovanka King, Fuad Abass, Abigail Cheung, Rachel Wallace, Samara Baldwin

“…We have previously shown that a novel treatment comprising a combination of the probiotic Lactobacillus rhamnosus CGMCC 1.3724 with peanut OIT (Probiotic Peanut Oral ImmunoTherapy (PPOIT)) is highly effective at inducing SU, with benefit persisting to 4 years after treatment cessation in the majority of initial treatment responders. …”
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Network Pharmacology and Molecular Docking Study on the Mechanism of the Therapeutic Effect of Strychni Semen in NSCLC by He Geng, Yujie Xue, Binghua Yan, Zhaoxue Lu, Hengjin Yang, Peng Li, Jundong Zhou

“…In addition, Strychni Semen’s effects on NSCLC involved mainly the Calcium pathway, the Estrogen pathway, and the cGMP-PKG and cAMP pathways. This study visually demonstrated the mechanism of the therapeutic effect of Strychni Semen in NSCLC through multiple components, targets and pathways which provides a basis for clinical treatment and further experimental research.…”
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Glycemic Variability Assessed by Continuous Glucose Monitoring and Short-Term Outcome in Diabetic Patients Undergoing Percutaneous Coronary Intervention: An Observational Pilot Stu... by Annunziata Nusca, Angelo Lauria Pantano, Rosetta Melfi, Claudio Proscia, Ernesto Maddaloni, Rocco Contuzzi, Fabio Mangiacapra, Andrea Palermo, Silvia Manfrini, Paolo Pozzilli, Germano Di Sciascio

“…Thus, our study investigated the usefulness of CGM in the setting of PCI where an optimal glycemic control should be achieved in order to prevent complications and improve outcome.…”
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Association of Body Fat Percentage with Time in Range Generated by Continuous Glucose Monitoring during Continuous Subcutaneous Insulin Infusion Therapy in Type 2 Diabetes by Yuting Ruan, Jiana Zhong, Rongping Chen, Zhen Zhang, Dixing Liu, Jia Sun, Hong Chen

“…All participants underwent 72 h CGM period during short-term CSII therapy. TIR was defined as the percentage of time spent within the target glucose range of 3.9-10.0 mmol/L. …”
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Towards a decision support system for post bariatric hypoglycaemia: development of forecasting algorithms in unrestricted daily-life conditions by Francesco Prendin, Olivia Streicher, Giacomo Cappon, Eva Rolfes, David Herzig, Lia Bally, Andrea Facchinetti

“…Conclusions Real-time forecasting of PBH events using CGM data as a single input imposes high demands on various types of prediction algorithms, with CGM data noise and rapid postprandial glucose dynamics representing the key challenges. …”
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