Combinatorial co-expression of xanthine dehydrogenase and chaperone XdhC from Acinetobacter baumannii and Rhodobacter capsulatus and their applications in decreasing purine content... by Chenghua Wang, Ran Zhang, Yu Sun, You Wen, Xiaoling Liu, Xinhui Xing

“…Naturally occurring xdhABC gene clusters of A. baumannii CICC 10254 and R. capsulatus CGMCC 1.3366 as well as two refactored clusters constructed by exchanging their xdhC genes were overexpressed in Escherichia coli and purified to near homogeneity. …”
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Pricing American Options by a Fourier Transform Multinomial Tree in a Conic Market by Weiwei Wang, Xiaoping Hu

“…Then, the American option pricing method based on reverse iteration is given. Finally, the CGMY process is used to demonstrate how to price the American put option in the Lévy conic market. …”
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Phosphodiesterase-5 Inhibitors: Action on the Signaling Pathways of Neuroinflammation, Neurodegeneration, and Cognition by Christina Alves Peixoto, Ana Karolina Santana Nunes, Ana Garcia-Osta

“…Mechanistically, PDE5-Is produce an anti-inflammatory and neuroprotection effect by increasing expression of nitric oxide synthases and accumulation of cGMP and activating protein kinase G (PKG), the signaling pathway of which is thought to play an important role in the development of several neurodiseases, such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and multiple sclerosis (MS). …”
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A case study on using a large language model to analyze continuous glucose monitoring data by Elizabeth Healey, Amelia Li Min Tan, Kristen L. Flint, Jessica L. Ruiz, Isaac Kohane

“…Abstract Continuous glucose monitors (CGM) provide valuable insights about glycemic control that aid in diabetes management. …”
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Enhancing Health Equity and Patient Engagement in Diabetes Care: Technology-Aided Continuous Glucose Monitoring Pilot Implementation Project by Madhur Thakur, Eric W Maurer, Kim Ngan Tran, Anthony Tholkes, Sripriya Rajamani, Roli Dwivedi

“…In this viewpoint, we share insights on the implementation of a CGM program at an FQHC, the Community-University Health Care Center (CUHCC) in Minneapolis, Minnesota. …”
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Prolonged Honeymoon Phase in Adult-Onset Type 1 Diabetes Mellitus: A Case Study by Pranjali Shah

“…Laboratory results showed uncontrolled hyperglycemia, absence of C-peptide, and positive for anti-GAD. Treatment involved CGMS fixation and insulin degludec/aspart, leading to excellent sugar control. …”
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Stimulators and Activators of Soluble Guanylate Cyclase: Review and Potential Therapeutic Indications by Bobby Nossaman, Edward Pankey, Philip Kadowitz

“…Two classes of compounds have been developed that can directly activate sGC and increase cGMP formation in pathophysiologic conditions when NO formation and bioavailability are impaired or when NO tolerance has developed. …”
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Activators of the 26S proteasome when protein degradation increases by Donghoon Lee

“…However, the activities of the 26S proteasome are also stimulated, especially under highly catabolic conditions such as those associated with atrophying skeletal muscle, proteotoxic stress such as heat shock and arsenite, or hormonal cues such as cAMP or cGMP agonists. Among the proteins that enhance proteasomal degradation are the PKA, PKG, UBL-UBA proteins and the Zn finger AN1-type domain (ZFAND) family proteins. …”
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Deletion of bZIP Transcription Factor <i>PratfA</i> Reveals Specialized Metabolites Potentially Regulating Stress Response in <i>Penicillium raistrickii</i> by Anxin Zhang, Shu Zhang, Xinran Xu, Wen-Bing Yin

“…In this study, we purposefully altered <i>PratfA</i>, a crucial regulator associated with oxidative stress in <i>Penicillium raistrickii</i> CGMCC 3.1066. After the knockout of <i>PratfA</i>, a novel polyketide (PK) raistrilide A (<b>1</b>) and the known nonribosomal peptide (NRP) tunicoidine (<b>2</b>) subsequently disappeared. …”
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Impact of Real-Time Continuous Glucose Monitoring Use on Glucose Variability and Endothelial Function in Adolescents with Type 1 Diabetes: New Technology—New Possibility to Decreas... by Milena Jamiołkowska, Izabela Jamiołkowska, Włodzimierz Łuczyński, Joanna Tołwińska, Artur Bossowski, Barbara Głowińska Olszewska

“…Real-time continuous glucose monitoring (RT-CGM) provides possibilities for the detection of glycaemic variability, newly recognized cardiovascular risk factor. …”
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Portable Gentle Jogger Improves Glycemic Indices in Type 2 Diabetic and Healthy Subjects Living at Home: A Pilot Study by Jose A. Adams, Veronica Banderas, Jose R. Lopez, Marvin A. Sackner

“…Continuous glucose monitoring (CGM) allows the investigation of glycemic control during activities of daily living. …”
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Intermediate-High Risk Pulmonary Embolism: The Use of Riociguat and Inferior Vena Cava Filter in a Situation of Recurrent Embolism following Insufficient Anticoagulation and Fibrin... by Anh Khoi Vo, Håkon Reikvam, Helga Midtbø, Jan Ludvig Wirsching, Øyvind Bruserud, Øystein Wendelbo

“…Important issues regarding the initial choice of anticoagulation, rescue thrombolytic therapy, and benefits of adding riociguat to stimulate the nitric oxide-soluble guanylate cyclase-cyclic guanosine monophosphate (NO-sGC-cGMP) pathway to improve the RV function are discussed. …”
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A Randomized Study to Compare the Effects of Once-Weekly Dulaglutide Injection and Once-Daily Glimepiride on Glucose Fluctuation of Type 2 Diabetes Mellitus Patients: A 26-Week Fol... by Huiqin Li, Xiaohua Xu, Jie Wang, Xiaocen Kong, Maoyuan Chen, Ting Jing, Zhiying Zhang, Guoping Yin, Xiaomei Liu, Yun Hu, Lei Ye, Xiaofei Su, Jianhua Ma

“…To evaluate the effects of once-weekly dulaglutide injection and once-daily glimepiride on glucose fluctuation in patients with type 2 diabetes mellitus (T2DM) using the Continuous Glucose Monitoring System (CGMS). Methods. A total of 23 patients with T2DM were randomly assigned into two groups for 26 weeks: the dulaglutide group (n=13) and the glimepiride group (n=10). 72-hour CGMS was applied to all patients: before and after the treatment. …”
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磷酸二酯酶5在肾脏纤维化中的保护作用 by 翟庆娴, 李蒙, 隆罗莎, 梁柏恩, 王蔚东

“…使用人近端小管上皮细胞（HK-2）给予TGF-β1 48 h，检测cGMP对内质网应激和纤维化相关蛋白水平的影响。使用衣霉素孵育HK-2细胞24 h，检测PDE5抑制剂对内质网应激、纤维化相关蛋白、自噬和凋亡蛋白水平的影响。…”
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Knowledge, Attitudes, and Practices of Chronic Type 2 Diabetes Patients in China Toward Continuous Glucose Monitoring: An Online Questionnaire Survey by Liu B, Wu X, Zou X, Sun F, Yu J

“…Knowledge indirectly impacted practice through its influence on attitude (β = 0.242, P = 0.010).Conclusion: Type 2 diabetes patients exhibited insufficient knowledge but positive attitudes and practices toward CGM. Recommends educational interventions to enhance knowledge, potentially improving CGM utilization and outcomes in this population. …”
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Changes in the intestinal microbiota of broiler chicken induced by dietary supplementation of the diatomite-bentonite mixture by E. Węsierska, P. Micek, M. G. Adamski, K. Gondek, M. Lis, M. Trela, D. Wojtysiak, J. Kowal, A. Wyrobisz-Papiewska, G. Kunstman, S. Mosiołek, K. Smoroń

“…Thirteen species occurred only in group E: Agathobaculum butyriciproducens, Anaerobutyricum hallii, Anaerobutyricum soehngenii, Blautia producta ATCC 27,340 = DSM 2950, Gordonibacter pamelaeae 7-10-1-b, Helicobacter pullorum NCTC 12,824, Lactobacillus crispatus, L. helveticus DSM 20,075 = CGMCC 1.1877, Mucispirillum schaedleri, Phascolarctobacterium faecium, Phocaeicola coprocola DSM 17,136, P. massiliensis, and Ruthenibacterium lactatiformans. …”
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Elevating Expectations: Vericiguat in Heart Failure with Reduced Ejection Fraction by Pushpraj Patel, Anjeney Mishra, Sachin Madhavrao Gawande, Akhilesh Patel, Amit Varshney

“…Vericiguat, a soluble guanylate cyclase stimulator, may serve as an adjunctive therapy by enhancing the nitric oxide (NO)-sGC-cyclic guanosine monophosphate (cGMP) pathway. Methods: This observational cohort study involved 100 participants with stage C HF and reduced EF (<40%), divided into two groups: 48 receiving vericiguat plus GDMT and 52 receiving GDMT alone. …”
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Phospho-relay feedback loops control egress vs. intracellular development in Toxoplasma gondii by Ja E. Claywell, Yong Fu, L. David Sibley

“…Perturbation of cyclic GMP (cGMP) vs. calcium demonstrates that PKAc1 acts on targets between guanylate cyclase and calcium release. …”
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Glu4: An open-source package for real-time forecasting and alerting post-bariatric hypoglycemia based on continuous glucose monitoring by Luca Cossu, Francesco Prendin, Giacomo Cappon, David Herzig, Lia Bally, Andrea Facchinetti

“…A run-to-run algorithm forecasts future glucose levels using past CGM data, identifying potential hypoglycemic events 30 min in advance. …”
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Effect of prepubertal caffeine consumption and recovery on adult erectile tissue functions in Wistar rats by Shakiru Salami, Bashua Kassim, Michael Allen, Hussein Salahdeen, Babatunde Murtala

“…Inhibitors of prostacyclin (indomethacin) and cGMP (methyl blue) militate caffeine-induced relaxation. …”
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