The absolute number of circulating Treg cells is reduced in difficult-to-treat RA patients and is ameliorated by low-dose IL-2 by Huanhuan Yan, Huanhuan Yan, Huanhuan Yan, Xiaoyu Zi, Xiaoyu Zi, Xiaoyu Zi, Huer Yan, Xiaoying Zhang, Xiaoying Zhang, Xiaoying Zhang, Jie Bai, Jie Bai, Jie Bai, Chong Gao, Xiaofeng Li, Xiaofeng Li, Xiaofeng Li, Caihong Wang, Caihong Wang, Caihong Wang

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The spatial landscape of cancer hallmarks reveals patterns of tumor ecological dynamics and drug sensitivity by Mustafa Sibai, Sergi Cervilla, Daniela Grases, Eva Musulen, Rossana Lazcano, Chia-Kuei Mo, Veronica Davalos, Arola Fortian, Adrià Bernat, Margarita Romeo, Collin Tokheim, Jordi Barretina, Alexander J. Lazar, Li Ding, Enrique Grande, Francisco X. Real, Manel Esteller, Matthew H. Bailey, Eduard Porta-Pardo, Enrique Grande, Teresa Alonso-Gordoa, Mario Álvarez-Maestro, Elena Andrada, Ainara Azueta, Raquel Benítez Javier Burgos, Daniel Castellano, M. Angel Climent, Mario Domínguez, Ignacio Durán Albert Font, Isabel Galante, Patricia Galván, Juan F. García, Xavier García del Muro, Félix Guerrero-Ramos, Núria Malats, Miriam Marqués, Pablo Maroto, Jaime Martínez de Villarreal, Ane Moreno-Oya, Jesús M. Paramio, Alvaro Pinto, Aleix Prat, Javier Puente, Oscar Reig, Francisco X. Real

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Volume contracted state, mortality and functional outcomes in patients with acute ischaemic stroke due to large vessel occlusion by Risheng Xu, Max Wintermark, Gregory W Albers, Jeremy J Heit, Adam A Dmytriw, Adrien Guenego, Yasmin Aziz, Kambiz Nael, Benjamin Pulli, Victor Urrutia, Dhairya A Lakhani, Tobias D Faizy, Argye Hillis, Vivek Yedavalli, Dylan Wolman, Licia P Luna, Elisabeth B Marsh, Hamza Adel Salim, Janet Mei, Vaibhav Vagal, Aakanksha Sriwastwa, Raf Llinas, Hanzhang Lu, Mona N Bahouth

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Corrosion and wear study of medium entropy Pb-Sn-Cu alloy for coating application by Gokul M. Pillai, Kuldeep Singh, Shanmugasundaram Thangaraju, Shashinath Jha, Vinod Kumar

“…A Vajra Lep made of Pb-Sn-Cu system reported in Varah Mihir's Jyotish Granth ''Brihat-Samhita'' inspired this research. The reported alloy in the present study was fabricated via the open induction casting method. …”
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Prevalence of potentially inappropriate prescribing in a subpopulation of older European clinical trial participants: a cross-sectional study by Manuel R Blum, Patricia M Kearney, Rose Galvin, Christine Baumgartner, Anette Van Dorland, Stephen Byrne, Nicolas Rodondi, Simon P Mooijaart, Carol Sinnott, Rosalinde K E Poortvliet, Jacobijn Gussekloo, David O Riordan, Carole Elodie Aubert, Kieran A Walsh, Robert S Du Puy, J Wouter Jukema, Vera McCarthy, Elaine K Walsh, Tinh-Hai Collet, Olaf M Dekkers

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Evolving trends in lung cancer risk factors in the ten most populous countries: an analysis of data from the 2019 Global Burden of Disease StudyResearch in context by Chinmay T. Jani, Samuel A. Kareff, Dan Morgenstern-Kaplan, Ana S. Salazar, Georgina Hanbury, Justin D. Salciccioli, Dominic C. Marshall, Joseph Shalhoub, Harpreet Singh, Estelamari Rodriguez, Gilberto Lopes

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Evaluating the World Health Organization’s Hearts Model for Hypertension and Diabetes Management: A Pilot Implementation Study in Guatemala by Irmgardt Alicia Wellmann, Luis Fernando Ayala, Taryn M. Valley, Vilma Irazola, Mark D. Huffman, Michele Heisler, Peter Rohloff, Rocío Donis, Eduardo Palacios, Manuel Ramírez-Zea, David Flood

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Visceral adipose tissue area and proportion provide distinct reflections of cardiometabolic outcomes in weight loss; pooled analysis of MRI-assessed CENTRAL and DIRECT PLUS dietary... by Hadar Klein, Hila Zelicha, Anat Yaskolka Meir, Ehud Rinott, Gal Tsaban, Alon Kaplan, Yoash Chassidim, Yftach Gepner, Matthias Blüher, Uta Ceglarek, Berend Isermann, Michael Stumvoll, Ilan Shelef, Lu Qi, Jun Li, Frank B. Hu, Meir J. Stampfer, Iris Shai

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Soluble and cell-based markers of immune checkpoint inhibitor-associated nephritis by Sandra M Herrmann, Riley Fadden, Ryan J Sullivan, Kerry L Reynolds, Harish Seethapathy, Meghan E Sise, Shruti Gupta, Alexandra-Chloe Villani, Qiyu Wang, Daiana Moreno, Destiny Harden, R Neal Smith, Ivy A Rosales, Robert B Colvin, Sarah Chute, Lynn D Cornell, Nancy J Yang, Sara Barmettler, Sophia Wells, Jocelyn Farmer

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Risk factors affecting polygenic score performance across diverse cohorts by Daniel Hui, Scott Dudek, Krzysztof Kiryluk, Theresa L Walunas, Iftikhar J Kullo, Wei-Qi Wei, Hemant Tiwari, Josh F Peterson, Wendy K Chung, Brittney H Davis, Atlas Khan, Leah C Kottyan, Nita A Limdi, Qiping Feng, Megan J Puckelwartz, Chunhua Weng, Johanna L Smith, Elizabeth W Karlson, Regeneron Genetics Center, Penn Medicine BioBank, Gail P Jarvik, Marylyn D Ritchie

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High risk of asthma among early teens is associated with quantitative differences in mite and cat allergen specific IgE and IgG4: a modified Th2 related antibody response revisited... by Thomas A. Platts-Mills, Behnam Keshavarz, Jeffrey M. Wilson, Sheryl L. Rifas-Shiman, Samuel M. Ailsworth, Joanne E. Sordillo, Lisa Workman, Martin Chapman, Jonas Lidholm, Emily Oken, Diane R. Gold

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Caesarean sections and private insurance: systematic review and meta-analysis by Ilir Hoxha, Medina Braha, Lamprini Syrogiannouli, David C Goodman, Peter Jüni, Bruno R da Costa

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Brief Mindfulness-Based Cognitive Therapy in Women With Myocardial Infarction by Tanya M. Spruill, PhD, Chorong Park, PhD, RN, Jolaade Kalinowski, EdD, Milla E. Arabadjian, PhD, RN, Yuhe Xia, MSc, Amanda J. Shallcross, ND, MPH, Pallavi Visvanathan, PhD, Nathaniel R. Smilowitz, MD, MS, Anaïs Hausvater, MD, Sripal Bangalore, MD, MHA, Hua Zhong, PhD, Ki Park, MD, Puja K. Mehta, MD, Dwithiya K. Thomas, MD, Jeffrey Trost, MD, Kevin R. Bainey, MD, Bobak Heydari, MD, Janet Wei, MD, Victoria Vaughan Dickson, PhD, RN, Gbenga Ogedegbe, MD, MPH, Jeffrey S. Berger, MD, MS, Judith S. Hochman, MD, Harmony R. Reynolds, MD

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Longitudinal analysis of lifestyle risk factors, nutrition status and drivers of food choice among urban migrants in Ulaanbaatar, Mongolia, and Almaty, Kazakhstan: a formative stud... by Sabri Bromage, Shamil Tazhibayev, Xin Zhou, Chang Liu, Enkhtsetseg Tserenkhuu, Oksana Dolmatova, Munkhbat Khishignemekh, Leyla Musurepova, Wusigale, Soninkhishig Tsolmon, Enkhjargal Tsendjav, Davaasambuu Enkhmaa, Rajesh Kumar Rai, Bayarmaa Enkhbat, Bilige Menghe, Davaasambuu Ganmaa

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Physiological accumulation of lipid droplets in the newborn liver during breastfeeding is driven by TLR4 ligands by Wanderson Ferreira da Silva Júnior, Karen Marques de Oliveira Costa, Hortência Maciel Castro Oliveira, Maísa Mota Antunes, Kassiana Mafra, Brenda Naemi Nakagaki, Pedro Sérgio Corradi da Silva, Júlia Duarte Megale, Sarah Campos de Sales, Douglas Carvalho Caixeta, Mário Machado Martins, Robinson Sabino-Silva, Cristina Maria Pinto de Paula, Luiz Ricardo Goulart, Rafael Machado Rezende, Gustavo Batista Menezes

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Congenital T-cell activation impairs transitional-to-follicular B-cell maturation in humans by Hugues Allard-Chamard, Kirsty Hillier, Michelle L. Ramseier, Alice Bertocchi, Naoki Kaneko, Katherine Premo, Grace Yuen, Marshall Karpel, Vinay S. Mahajan, Christina Tsekeri, Joseph S. Hong, Jean Vencic, Rory Crotty, Anish V. Sharda, Sara Barmettler, Emma Westermann-Clark, Jolan E. Walter, Musie Ghebremichael, Alex K. Shalek, Jocelyn R. Farmer, Shiv Pillai

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Emergency Medicine Palliative Care Access (EMPallA): protocol for a multicentre randomised controlled trial comparing the effectiveness of specialty outpatient versus nurse-led tel... by Jeanne Cho, Michael Hill, Corita R Grudzen, Deborah J Shim, Abigail M Schmucker, Keith S Goldfeld, Lauren Southerland, Jeffrey M Caterino, Marie-Carmelle Elie, Robert Swor, Susan E Cohen, Arum Kim, Joseph Lowy, Jennifer S Scherer, Nancy E Bael, Ellin Gafford, Joshua Lakin, Paige Barker, Angela Chmielewski, Jennifer Kapo, Audrey Tan, Rebecca Yamarik, Susan Salz, Stephen Ryan, Anne Kim, Isabel Castro, Amelia Hargrove, Laura Stuecher, Nora Daut, Juanita Booker-Vaughns, Garrett K Chan, J Nicholas Dionne-odom, Patrick Dunn, Robert Galvin, Ernest A Hopkins III, Margaret M Maguire, Neha Reddy Pidatala, Dawn Rosini, Sally Welsh, Karen Jubanyik, Ada L Rubin, Kei Ouchi, Rebecca Murray, Nicole Tang, Marie Bakitas, Abraham Brody, Caroline Blaum, Mara Flannery, Richard Tamirian, Pamela Marsack, Jennifer Bonito, Romilla Batra, Donna C Sadasivan, Eric David Isaacs, Constance L Kizzie-Gillett, William K Vaughan, Pluscedia G Williams, Angela Young-Brinn

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Refreshing medical students’ intravenous-cannulation skills: a blinded observer three-arm randomised comparison of mental imagery, part-task trainer simulation and written instruct... by Robert Greif, Joana Berger-Estilita, Rafael Blülle, Daniel Stricker, Mathias Balmer, Christoph Berendonk

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Global Patterns of Prostate Cancer Incidence, Aggressiveness, and Mortality in Men of African Descent by Timothy R. Rebbeck, Susan S. Devesa, Bao-Li Chang, Clareann H. Bunker, Iona Cheng, Kathleen Cooney, Rosalind Eeles, Pedro Fernandez, Veda N. Giri, Serigne M. Gueye, Christopher A. Haiman, Brian E. Henderson, Chris F. Heyns, Jennifer J. Hu, Sue Ann Ingles, William Isaacs, Mohamed Jalloh, Esther M. John, Adam S. Kibel, LaCreis R. Kidd, Penelope Layne, Robin J. Leach, Christine Neslund-Dudas, Michael N. Okobia, Elaine A. Ostrander, Jong Y. Park, Alan L. Patrick, Catherine M. Phelan, Camille Ragin, Robin A. Roberts, Benjamin A. Rybicki, Janet L. Stanford, Sara Strom, Ian M. Thompson, John Witte, Jianfeng Xu, Edward Yeboah, Ann W. Hsing, Charnita M. Zeigler-Johnson

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Neutralizing antibody immune correlates in COVAIL trial recipients of an mRNA second COVID-19 vaccine boost by Bo Zhang, Youyi Fong, Lauren Dang, Jonathan Fintzi, Shiyu Chen, Jing Wang, Nadine G. Rouphael, Angela R. Branche, David J. Diemert, Ann R. Falsey, Daniel S. Graciaa, Lindsey R. Baden, Sharon E. Frey, Jennifer A. Whitaker, Susan J. Little, Satoshi Kamidani, Emmanuel B. Walter, Richard M. Novak, Richard Rupp, Lisa A. Jackson, Chenchen Yu, Craig A. Magaret, Cindy Molitor, Bhavesh Borate, Sydney Busch, David Benkeser, Antonia Netzl, Derek J. Smith, Tara M. Babu, Angelica C. Kottkamp, Anne F. Luetkemeyer, Lilly C. Immergluck, Rachel M. Presti, Martín Bäcker, Patricia L. Winokur, Siham M. Mahgoub, Paul A. Goepfert, Dahlene N. Fusco, Robert L. Atmar, Christine M. Posavad, Jinjian Mu, Mat Makowski, Mamodikoe K. Makhene, Seema U. Nayak, Paul C. Roberts, Peter B. Gilbert, Dean Follmann, Coronavirus Variant Immunologic Landscape Trial (COVAIL) Study Team

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