Glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide agonists for the treatment of obesity and diabetes mellitus by Alexander C. Martins, Beatriz G. de la Torre, Fernando Albericio

“…Pharmaceutical interventions play a vital role in managing various conditions, including weight-related issues such as obesity. …”
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DIGITALIZATION OR DIGITAL ECONOMY: PROBLEMS AND PERSPECTIVES by L. Ivanovskaya

“…Two different tendencies in the «digitalization» of a social life: one creates real opportunities of historical breakthrough of all mankind to improve its life conditions; the other, dangerous for human being is a possibility of a “cyber slavery”, have been distinguished. …”
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Quantifying the crossover from capillary fingering to viscous fingering in heterogeneous porous media by Xin Yang, Xingfu Li, Bo Kang, Bin Xu, Hehua Wang, Xin Zhao, Bo Zhang, Kai Jiang, Shitao Liu, Yanbing Tang

“…Our model quantifies capillary and viscous fingering characteristics while investigating porous media heterogeneity's role in the crossover zone. Analysis of simulation results reveals that a higher characteristic front flow rate within the crossover zone leads to earlier breakthrough and reduced displacement efficiency. …”
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CalciumZero: a toolbox for fluorescence calcium imaging on iPSC derived brain organoids by Xiaofu He, Yian Wang, Yutong Gao, Xuchen Wang, Zhixiong Sun, Huixiang Zhu, Kam W. Leong, Bin Xu

“…Abstract Calcium plays an important role in regulating various neuronal activities in human brains. …”
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CD8+ T cells from SIV elite controller macaques recognize Mamu-B*08-bound epitopes and select for widespread viral variation. by John T Loffredo, Thomas C Friedrich, Enrique J León, Jason J Stephany, Denise S Rodrigues, Sean P Spencer, Alex T Bean, Dominic R Beal, Benjamin J Burwitz, Richard A Rudersdorf, Lyle T Wallace, Shari M Piaskowski, Gemma E May, John Sidney, Emma Gostick, Nancy A Wilson, David A Price, Esper G Kallas, Helen Piontkivska, Austin L Hughes, Alessandro Sette, David I Watkins

“…<h4>Background</h4>It is generally accepted that CD8+ T cell responses play an important role in control of immunodeficiency virus replication. …”
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Bibliotherapy Services in Public Libraries: the Case of Lithuania by Jurgita Girčienė, Miglė Damijonaitytė

“…Summarizing the data of the latest research presented in the article and previous secondary sources, it can be stated that in the early 21st century, library bibliotherapy began to be developed at the formal level, and after the development breakthrough recorded at the turn of the first and second decades it has already established itself as a service provided by Lithuanian public libraries. …”
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Assessing favipiravir impact on SARS-CoV-2 transmission within households: Insights from a multi-center study (FaviPrev) by Taweegrit Siripongboonsitti, Marisa Muadchimkaew, Kriangkrai Tawinprai, Ornisa Issaranon, Wichuda Meepholkij, Pureepat Arttawejkul, Apiradee Vararungzarit, Onwalee Dhissayakamol, Wilaiporn Preeyachit, Kamonwan Soonklang, Nithi Mahanonda

“…This breakthrough highlights its potential in broader public health strategies. …”
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In-situ/operando study of Cu-based nanocatalysts for CO2 electroreduction using electrochemical liquid cell TEM by Jiawei Wan, Jiawei Wan, Qiubo Zhang, Ershuai Liu, Ershuai Liu, Yi Chen, Yi Chen, Jiana Zheng, Jiana Zheng, Amy Ren, Walter S. Drisdell, Walter S. Drisdell, Haimei Zheng, Haimei Zheng

“…We highlight the platform’s crucial role in elucidating atomic-scale pathways of nanocatalyst restructuring and identifying catalytic active sites, as well as avoiding potential artifacts to ensure unbiased conclusions. …”
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Association among high blood pressure health literacy, social support and health-related quality of life among a community population with hypertension: a community-based cross-sec... by Ting Chen, Wei Gan, Li Song, Yujie Wang, Huan Qi, Qinghua Zhang, Jinyu Yin

“…Community intervention for hypertension management should consider HBP-HL promotion and social engagement as the breakthrough points to increase the impact on patients’ HRQoL.…”
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Study of Modern Human Evolution via Comparative Analysis with the Neanderthal Genome by Musaddeque Ahmed, Ping Liang

“…Even though a number of comparisons have been made sporadically between Neanderthals and modern humans, mostly following a candidate gene approach, the major breakthrough took place with the sequencing of the Neanderthal genome. …”
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Soviet Researchers on the Middle East: Ahead of Their Time by I. D. Zvyagelskaya

“…The article attempts to consider some breakthrough ideas and assessments of historical events in the Middle East put forward by the Soviet experts. …”
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Chimeric cytokine receptor TGF-β RⅡ/IL-21R improves CAR-NK cell function by reversing the immunosuppressive tumor microenvironment of gastric cancer by Yaojun Ren, Min Xue, Xinhui Hui, Xiuyu Liu, Muhammad Asad Farooq, Yiran Chen, Yuzhou Ji, Yixin Duan, Iqra Ajmal, Jie Yao, Wenzheng Jiang

“…Natural killer (NK) cells play a crucial role in the body’s anti-cancer defense, and chimeric antigen receptor (CAR)–NK cell therapy is gaining attention as a cutting-edge and promising treatment method. …”
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UPDATE ON CYTOMEGALOVIRUS INFECTION MANAGEMENT IN ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANT RECIPIENTS by José Luis Piñana, Estela Giménez, Lourdes Vázquez, María Ángeles Marcos, Manuel Guerreiro, Rafael Duarte, Ariadna Pérez, Carlos de Miguel, Ildefonso Espigado, Marta González-Vicent, María Suarez-Lledó, Irene García-Cadenas, Rodrigo Martino, Angel Cedillo, Monserrat Rovira, Rafael de la Cámara, David Navarro, Carlos Solano

“…Strategies for tailoring LMV prophylaxis, managing breakthrough DNAemia, and implementing secondary prophylaxis in refractory cases were outlined. …”
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AiGPro: a multi-tasks model for profiling of GPCRs for agonist and antagonist by Rahul Brahma, Sunghyun Moon, Jae-Min Shin, Kwang-Hwi Cho

“…Abstract G protein-coupled receptors (GPCRs) play vital roles in various physiological processes, making them attractive drug discovery targets. …”
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Potential drug targets for asthma identified through mendelian randomization analysis by Xingxuan Chen, Yu Shang, Danting Shen, Si Shi, Zhe Wen, Lijuan Li, Hong Chen

“…Abstract Background The emergence of new molecular targeted drugs marks a breakthrough in asthma treatment, particularly for severe cases. …”
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DGAT1 Expression Promotes Ovarian Cancer Progression and Is Associated with Poor Prognosis by Leilei Xia, Ye Wang, Shengyun Cai, Mingjuan Xu

“…Diacylglycerol O-acyltransferase 1 (DGAT1) can synthesize triglycerides by transferring acyl-CoA to diacylglycerol, which plays a key role in lipid synthesis. However, the role of DGAT1 in ovarian cancer is not yet elucidated. …”
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Quantum Contextual Hypergraphs, Operators, Inequalities, and Applications in Higher Dimensions by Mladen Pavičić

“…Quantum contextuality plays a significant role in supporting quantum computation and quantum information theory. …”
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La mécanique des fluides en France dans la première moitié du xxe siècle by Charru, François

“…This reveals a fruitful interwar period, which prepares the prominent role played by France in the creation in 1946 of the International Union of Theoretical and Applied Mechanics (IUTAM). …”
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Forming the Research Component of the U.S. Defense Budget Policy by A. V. Balyshev, V. I. Konnov

“…The article offers specific cases to illustrate the role of key players of the U.S. budgetary process, the U.S. …”
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HYDROPONICS: ADVANTAGES AND CHALLENGES IN SOILLESS FARMING by Lokendra Khatri, Adhiraj Kunwar, Dipak Raj Bist

“…By overcoming the existing challenges through research and development, hydroponics can play a key role in improving food production, especially in urban areas with limited arable land.…”
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