The Effect of Mesenchymal Stem Cell-Derived Exosomes and miR17-5p Inhibitor on Multicellular Liver Fibrosis Microtissues by Farnaz Sani, Mina Soufi Zomorrod, Negar Azarpira, Masoud Soleimani

“…Furthermore, EXO + anti-miR had the best effects on boosting the fibrotic markers. Therefore, we propose this novel MLM model to understand fibrosis mechanisms better and develop new drugs.…”
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Identification of WDR74 and TNFRSF12A as biomarkers for early osteoarthritis using machine learning and immunohistochemistry by Yiwei Chen, Yiwei Chen, Jiali Lin, Detong Shi, Yu Miao, Yu Miao, Feng Xue, Feng Xue, Kexin Liu, Kexin Liu, Xiaotao Wang, Changqing Zhang, Changqing Zhang

“…We employed XGBoost, a gradient-boosting ML algorithm, to identify core URGs and construct a diagnostic model. …”
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Association of workforce participation with depression among US older adults: results from NHANES 2005–2018 by Zhenyu Sun, Yi Wang, Xi Chen, Dongfu Qian

“…Abstract Background The challenges of global aging would boost more workforce participation of older adults, and depression rate was increasing among older adults. …”
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Effect of bleaching and repolishing on whiteness change and staining susceptibility of resin-based materials by Sultan Aktuğ Karademir, Samet Atasoy, Beyza Yılmaz

“…The samples were randomly divided into four treatment groups: control (distilled water, 14 days), in-office bleaching (Opalescence Boost-40% HP, 3*20min), at-home bleaching (Opalescence PF-16% CP, 6 h, 14 days), and toothpaste group (Opalescence Whitening, 2*5min, 14 days) (n:8). …”
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Early embryonic thermal programming and post-hatch flavonoid (Scutellaria baicalensis) supplementation enhanced immune response markers in broiler chickens by Sadid Al Amaz, Md Ahosanul Haque Shahid, Rajesh Jha, Birendra Mishra

“…When combined with baicalein, TM mitigated the negative effects of heat stress by boosting key immune-related gene expression in the spleen, bursa, and thymus.…”
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Cervical cancer screening utilization among HIV-positive women in Edo State, Nigeria by Ngozi R. Osunde, Mercy N. Anayo, Ona Patience, Favour E. Omoregie

“…As a result, it is recommended that enhancing healthcare workers’ abilities to promote cervical cancer awareness and encourage adherence to screening within this population is crucial to boost uptake.…”
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The Influence of Digital Talent Development and Green Innovation and The Use of Green Innovation As Mediation To Measure Data Centre Performance by Rifa Herdian, Mohammad Syamsul Maarif, Anggraini Sukmawati, Irman Hermandi

“…Originality/value (State of the art): This study highlights the unique role of green practices in boosting energy efficiency, operational sustainability, and competitiveness in the data center business despite regulatory and talent shortages by using renewable energy and modern technologies. …”
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Exogenous organic acids promoted phytoremediation by Hydrangea macrophylla in cadmium‑contaminated soil by Yunjing Song, Qian Cheng, Bing Zhao

“…Furthermore, organic acids reduced the level of membrane lipid peroxidation in leaves, increased plant biomass and promoted root growth of H. macrophylla. By boosting superoxide dismutase (SOD), peroxidase (POD), and catalase activities (CAT), elevating levels of proline (Pro), non-protein thiol (NPT), glutathione (GSH) and phytochelatins (PCs), exogenous organic acids promoted the Cd tolerance of H. macrophylla. …”
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Using Deep Learning to Identify High-Risk Patients with Heart Failure with Reduced Ejection Fraction by Zhibo Wang, Xin Chen, Xi Tan, Lingfeng Yang, Kartik Kannapur, Justin L. Vincent, Garin N. Kessler, Boshu Ru, Mei Yang

“…For comparison, we also tested multiple traditional machine learning models including logistic regression, random forest, and eXtreme Gradient Boosting (XGBoost). Model performance was assessed by area under the curve (AUC) values, precision, and recall on an independent testing dataset. …”
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Decreased SynMuv B gene activity in response to viral infection leads to activation of the antiviral RNAi pathway in C. elegans. by Ashwin Seetharaman, Himani Galagali, Elizabeth Linarte, Mona H X Liu, Jennifer D Cohen, Kashish Chetal, Ruslan Sadreyev, Alex J Tate, Taiowa A Montgomery, Gary Ruvkun

“…The enhanced RNAi and conservation of the dREAM complex mutants suggests new therapeutic avenues to boost antiviral defenses.…”
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Optimizing Growth and Yield in Mulched Cotton Through Aerated Subsurface Drip Irrigation in Southern Xinjiang by Yuxi Zhang, Baolin Yao, Peining Niu, Zhu Zhu, Yan Mo, Fayong Li, Sanmin Sun

“…Furthermore, aerating combined with increased irrigation quotas resulted in higher seed cotton yields, with aerated irrigation boosting yields by 1.79% in 2021 and 4.43% in 2022 compared to non-aerated irrigation. …”
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The Utility of Synovial Fluid Interleukin-10 in Diagnosing Chronic Periprosthetic Joint Infection: A Prospective Cohort Study by Zou Y, Yang Y, Yang J, Zhang Y, Zhao C, Qin L, Hu N

“…However, limited research has explored the diagnostic potential of SF IL-10 in chronic PJI patients.Objective: The study aimed to investigate the relationship between SF IL-10 and incidence of chronic PIJ, and to evaluate its diagnostic reliability.Design and Methods: We analyzed data from 137 patients who underwent revision surgery for aseptic loosening or chronic PJI between 2017 and 2019 in our hospital. …”
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Metformin exerted tumoricidal effects on colon cancer tumoroids via the regulation of autophagy pathway by Roya Shabkhizan, Çığır Biray Avci, Sanya Haiaty, Marziyeh Sadat Moslehian, Fatemeh Sadeghsoltani, Ahad Bazmani, Mahdi Mahdipour, Leila Sabour Takanlou, Maryam Sabour Takanlou, Arezoo Rezaie Nezhad Zamani, Reza Rahbarghazi

“…Histological examination confirmed the loosening integrity of tumoroids in MTF-treated groups, especially 120 mM MTF, with the increase in cell death via the induction of apoptosis (chromatin marginalization) and necrotic (pyknotic nuclei) changes. …”
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Symmergent Gravity, Seesawic New Physics, and Their Experimental Signatures by Durmuş Demir

“…This emergent curvature cures the UV sensitivity and incorporates GR as symmetry-restoring emergent gravity (symmergent gravity, in brief) if a new physics sector (NP) exists to generate the Planck scale and if SM+NP is Fermi-Bose balanced. This setup, carrying fingerprints of trans-Planckian SUSY, predicts that gravity is Einstein (no higher-curvature terms), cosmic/gamma rays can originate from heavy NP scalars, and the UV cutoff might take right value to suppress the cosmological constant (alleviating fine-tuning with SUSY). …”
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MANAGING FRAUD IN CONTEMPORARY BUSINESS ENVIRONMENT, THE ROLE OF INFORMATION SECURITY MANAGEMENT: A STUDY OF QUOTED DEPOSIT MONEY BANKS (DMBs) IN NIGERIA by Onajero Kensington OHWO

“…Every economy relies on the banking sector to boost economic growth and development because of its intermediary role. …”

Levels of Cadmium, Copper, and Lead in Soils and Cassava Tubers Grown in Machakos County, Kenya by E. M. Kasyoka, G. W. Mbugua, R. N. Wanjau, G. N. Nambafu, J. N. Ndiritu

“…Large quantities of agrochemicals are regularly applied in coffee farms to control pests and diseases and provide adequate nutrients to boost yields. Agrochemicals have varied amounts of heavy metals and their prolonged use to attain maximum yields contributes to the contamination of soil, surface, and groundwater. …”
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Improving machine learning predictions to estimate fishing effort using vessel's tracking data by J. Samarão, A. Moreno, M.B. Gaspar, M.M. Rufino

“…We assessed seven supervised ML algorithms, including Logistic Regression, Ridge Classifier, Random Forest Classifier, K-Neighbours, Gradient Boosting Classifier, LinearSVC, Recurrent Neural Networks and XGBoost, using four case studies, from bivalve dredge and octopus pots and traps fisheries.First, in a preliminary statistical analysis between common error measures derived from the confusion matrix was decided to use accuracy, precision, and sensitivity as evaluation criteria. …”
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Intranasal delivery of hMSC-derived supernatant for treatment of ischemic stroke by inhibiting the pro-inflammatory polarization of neutrophils by Yixiang Jiang, Ning Wang, Jingyi Liu, Haoran Ren, Wenkang Jiang, Yanting Lei, Xidan Fu, Miao Hao, Xiujuan Lang, Yumei Liu, Xijun Liu, Rui Li, Hulun Li

“…Intranasal delivery of hMSC-L and hMSC-M significantly reduces neutrophil infiltration in the brain post-stroke and increases the proportion of anti-inflammatory N2-subtype neutrophils, boosting the expression levels of IL-10 and TGF-β. …”
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Classification of Nanomaterial Drug Delivery Systems for Inflammatory Bowel Disease by Wang H, Zhou F, Shen M, Ma R, Yu Q

“…These formulations can enhance a drug’s pharmacokinetics by modifying its properties, improve its ability to cross barriers, and boost bioavailability. In addition, NDDS can enable targeted delivery, increase local drug concentrations, improve efficacy, and reduce side effects, as well as protecting active drug molecules from immune recognition and protease degradation. …”
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Physiological impact of Trichoderma viride agents on the quality and production of melon that is grown on soils continuously cropped to melon by Jingyi Liu, Hua Lian, Jingwei Dou, Jingjing Li, Guangliang Zhu, Jiatong Wang, Guangshu Ma, Mei Li

“…Melon quality and yield was also enhanced by the use of T. viride agents, with the treatment of 6.4 × 105 CFU/g T. viride agents having the best boosting effects. The melon fruit’s transverse diameter, vertical diameter, single fruit weight, and yield all increased. …”
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