The sphingosine‐1‐phosphate signaling pathway (sphingosine‐1‐phosphate and its receptor, sphingosine kinase) and epilepsy by Lin Wang, Qingxia Kong, Xinyi Leng, Howan Leung, Yang Li

“…It can not only act as a second messenger in cells to activate downstream signaling pathways but can also exert biological effects by being secreted outside cells and binding to S1P receptors on the cell membrane. …”
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Study on the potential diagnostic value of metabolomics changes in different biological fluids for aspiration pneumonia by Lianghui Chen, Yazhen Chen, Fansen Lin, Jianbao Wang, Hongzhi Gao, Yuqi Liu

“…Abstract Background Aspiration pneumonia (AP) is a type of lung inflammation caused by the aspiration of food, oropharyngeal secretions, or gastric contents. This condition is particularly common in older adults and individuals with impaired swallowing or consciousness. …”
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Antagonism of Eucalyptus endophytic fungi against some important crop fungal diseases by Parmida Aleahmad, Leila Ebrahimi, Naser Safaie, Hassan Reza Etebarian

“…VL3 were selected for further investigation, which included examining their chitinase and cellulase secretion capabilities as potential antagonism mechanisms and their ability to solubilize phosphate as a growth-promoting mechanism. …”
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Erbin Regulates Tissue Factors Through Ras/Raf Pathway in Coagulation Disorders in Sepsis by Yang C, Lei C, Jing G, Xia Y, Zhou H, Wu D, Zuo J, Gong H, Wang X, Dong Y, Aidebaike D, Wu X, Song X

“…In vivo studies have shown that mice with Erbin deletion have more obvious enhanced coagulation function, and in vitro studies have shown that Erbin knockout mediated macrophage secretion of TF by activating the Ras/Raf pathway.Conclusion: Erbin reduces the coagulation activation by inhibiting TF release from macrophages.Keywords: Erbin, coagulation disorders, sepsis, tissue factor, macrophage…”
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A Case of Exacerbation of Chronic Pancreatitis Against the Background of COVID-19 Complicated by Pancreaticopleural Fistula with Enzymatic Pleurisy by I. I. Kotov, I. Yu. Kalinina, A. R. Propp, D. A. Sulim

“…It was possible to restore the normal passage of bile and pancreatic secretions, as well as to stop the functioning of the pancreaticopleural fistula using pancreatoduodenal resection. …”
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Impacts of Tax Laws on the Performance of Small and Medium Enterprises: A Case Study of Kabale Municipality Kabale District. by Abaasa, Ruth

“…The findings showed that 80 (53.3%) of respondents agreed that SMEs are typically subject to corporate income tax on their profits, with tax rates varying by country and annual income brackets. Some regions offer preferential tax rates or incentives for SMEs. …”
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Assessing the Effects of Tourism Activities on the Preservation of Cultural Heritage Among Communities of Rubanda DistrictUganda. by Ahabwe, John Brighton

“…Incorporating cultural studies into school curricula to teach younger generations about their heritage, some respondents also showed that storytelling remains a vital method of preserving history and culture, some respondents agreed that the crafting of items like baskets, mats, and pottery is common in Rubanda. Some respondents also showed that tourism brings economic benefits to local communities, providing an incentive to preserve cultural heritage, some respondents also showed that tourism creates employment opportunities for local residents, particularly in guiding. …”
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"Discernment of Spirits" in the theology of Hans Urs von Balthasar and the "The Synodal Way" project in Germany by Przemysław Kocjan

“…Die Unterscheidung der Geister hat eine lange, faszinierende Geschichte und deckt sich mit den Ereignissen des menschlichen Geistes. …”
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Enhanced myofibroblast differentiation of eMSCs in intrauterine adhesions by Jun Song, Meiqi Li, Yuan Tao, Yumeng Li, Canrong Mai, Jingting Zhang, Lan Yao, Shaoquan Shi, Jianyong Xu

“…The isolated eMSCs from IUA and controls show similar functions from the perspectives of cell morphology, proliferation, colony formation, exosome secretion, positive ratio of eMSC markers and conventional MSC markers, tri-differentiation efficiency, the ability of suppressing lymphocyte proliferation, cell aging, and promoting vascular tube formation. …”
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LDHA-mediated glycolysis in stria vascularis endothelial cells regulates macrophages function through CX3CL1-CX3CR1 pathway in noise-induced oxidative stress by Ying Yi, Min-Yu Wu, Kai-Tian Chen, An-Hai Chen, Lin-Qiu Li, Qin Xiong, Xian-Ren Wang, Wen-Bin Lei, Guan-Xia Xiong, Shu-Bin Fang

“…We found that CX3CL1 secretion from SV-ECs was decreased following LDHA inhibition and exhibited anti-inflammatory effects on Mφ via the CX3CR1 pathway. …”
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Ficus deltoidea standardized methanolic extract improves kidney structure and function against streptozotocin-induced diabetic nephropathy in rats by Nurdiana Samsulrizal, Noor Syaffinaz Noor Mohamad Zin, Nur Syimal`ain Azmi, Mohd Daud Bakar, Hafandi Ahmad, Yong-Meng Goh

“…We have previously demonstrated that Ficus deltoidea increases insulin secretion and improves tissue regeneration by reducing oxidative stress in diabetic rats. …”
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Genome-wide transcriptome analysis and drug target discovery reveal key genes and pathways in thyroid cancer metastasis by Minjing Zou, Amal Qattan, Monther Al-Alwan, Hazem Ghebeh, Naif Binjumah, Latifa Al-Haj, Khalid S. A. Khabar, Abdulmohsen Altaweel, Falah Almohanna, Abdullah M. Assiri, Abdelilah Aboussekhra, Ali S. Alzahrani, Ali S. Alzahrani, Yufei Shi

“…Notably, IL-6-mediated inflammatory and PD-L1 pathways were highly active in Met cells with increased secretion of pro-inflammatory and pro-metastatic cytokines such as CCL2, CCL11, IL5, IL6, and CXCL5. …”
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Reliea® combination of Codonopsis lanceolata and Chaenomeles sinensis extract alleviates airway inflammation on particulate matter 10 plus diesel exhaust particles (PM10D) ‑induced... by Yoon-Young Sung, Won-Kyung Yang, Jong Hoon Kim, Dongseok Shin, Seok June Son, Seung-Hyung Kim

“…In addition, RelA showed better expectoration through increased phenol red secretion. These results indicate that Reliea® combination of C. lanceolata and C. sinensis extract might be effective in prevention and treatment of airway inflammation and respiratory diseases.…”
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Multi-omics reveals that ST6GAL1 promotes colorectal cancer progression through LGALS3BP sialylation by Yuanchao Shi, Zhenzhong Pan, Jingwei Duan, Zexing Wang, Yiliang Fang, Bo Tang, Quanlin Guan

“…Importantly, we found that knockdown of lectin galactoside-binding soluble 3-binding protein (LGALS3BP), a newly identified secreted substrate of ST6GAL1, significantly blocked the proliferation, invasion, and chemoresistance of CRC cells induced by ST6GAL1 overexpression. …”
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Bioelectric stimulation outperforms brain derived neurotrophic factor in promoting neuronal maturation by María del Pilar Diego-Santiago, María Ujué González, Esther María Zamora Sánchez, Nuria Cortes-Carrillo, Carlos Dotti, Francesc Xavier Guix, Sahba Mobini

“…Moreover, ES altered the concentration and protein cargo of secreted extracellular vesicles (EV). ES with large enough accumulated charge significantly enriched EV proteome associated with neural development and function. …”
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Fractional-order PID feedback synthesis controller including some external influences on insulin and glucose monitoring by Kottakkaran Sooppy Nisar, Muhammad Farman, Khadija Jamil, Saba Jamil, Evren Hincal

“…A novel fractional-order diabetes mellitus model is proposed, incorporating a nonsingular, nonlocal kernel (Mittag-Leffler function) to account for the effect of epinephrine on suppressing insulin secretion and the dynamics of beta-cell mass. As beta-cell mass increases in the presence of adrenaline, the system remains highly responsive to rising blood glucose and falling insulin levels, driven by the hormone’s suppressive effects. …”
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Transcriptome and chromatin accessibility landscape of ovarian development at different egg-laying stages in taihe black-bone silky fowls by Jingyi Zhang, Yong Cui, Jiming Ruan, Haiyan Zhu, Haiping Liang, Ji Cao, Qing Wei, Jianzhen Huang

“…Compared to the late laying period, several genes related to ovarian development and reproductive hormone secretion, including TDRD5, CCNO, CYP17A1, BMP15, and STAR, were upregulated during the peak egg-laying period. …”
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Co-modulation of a circular form of PCDH11Y during neuroendocrine differentiation of prostate cancer by Giovanni Pecoraro, Ilaria Leone, Silvia Nuzzo, Santiago Negueruela, Giovanni Smaldone, Lorena Buono

“…Additionally, circPCDH11Y was detected in extracellular vesicles (EVs) secreted by LNCaP cells post-NED, suggesting its potential as a circulating biomarker. …”
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Comparison of phenotypic and genetic traits of ESBL-producing UPEC strains causing recurrent or single episode UTI in postmenopausal women by Michelle Kalu, Peter Jorth, Annie Wong-Beringer

“…Virulence factors such as type 1 fimbriae adhesin FimH, the outer membrane protease OmpT, and the secreted pore-forming toxin α-hemolysin (HlyA) have been shown to support the formation of intracellular bacterial communities (IBCs) within bladder epithelial cells (BECs), facilitating persistence. …”
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Conventional type 1 dendritic cells in the lymph nodes aggravate neuroinflammation after spinal cord injury by promoting CD8+ T cell expansion by Li-Qing Wang, Xiao-Yi Wang, Yue-Hui Ma, Heng-Jun Zhou

“…Interferon-γ promoted the secretion of Flt3L by LN-FSCs through the activation of JAK/STAT signaling pathway and enhanced the differentiation of pre-DCs into CD8α+ cells. …”
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