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  1. 741

    Coupling of an Au@AgPt nanozyme array with an micrococcal nuclease-specific responsiveness strategy for colorimetric/SERS sensing of Staphylococcus aureus in patients with sepsis by Xueqin Huang, Yingqi Yang, Hanlin Zhou, Liping Hu, Annan Yang, Hua Jin, Biying Zheng, Jiang Pi, Jun Xu, Pinghua Sun, Huai-Hong Cai, Xujing Liang, Bin Pan, Junxia Zheng, Haibo Zhou

    Published 2025-02-01
    “…In the presence of S. aureus, the secreted MNase preferentially cut the nucleobase AT-rich regions of DNA sequences on magnetic beads (MBs) to release alkaline phosphatase (ALP), which subsequently mediated the oxTMB reduction for inducing the colorimetric/SERS signal fade away. …”
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  2. 742

    Alpha-defensins increase NTHi binding but not engulfment by the macrophages enhancing airway inflammation in Alpha-1 antitrypsin deficiency by Jungnam Lee, Naweed Mohammad, Kyudong Han, Kyudong Han, Tammy Flagg-Dowie, Maria Magallon, Mark L. Brantly, Karina A. Serban, Karina A. Serban

    Published 2025-02-01
    “…The decreased phagocytosis was associated with TLR4 activation, downstream signaling via NF-κB p65 and marked increased secretion of inflammatory cytokines, CXCL8, IL-1b, and TNFα by the α-defensin-treated and NTHi-infected MDMs. …”
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  3. 743

    Avaliação das funções executivas em idosos acometidos por doenças crónico-degenerativas by Ivone Lúcia Brito, Silvia Coutinho Areosa, Regina Maria Fernandes Lopes, Irani l. de Lima Argimon

    Published 2012-01-01
    “…El diseño fue un estudio cuantitativo y transversal, con los instrumentos: hoja de datos socio-demográficos, prueba Wisconsin Card (WCST), inventario de depresión de Beck (BDI-I), inventario de ansiedad de Beck (BAI) y la escala de depresión geriátrica (GDS). …”
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  4. 744

    Insect Management for Leafy Vegetables (Lettuce, Endive and Escarole) by Gregg S. Nuessly, Susan E. Webb

    Published 2005-12-01
    “…Major pests of these crops are beet and southern armyworms, cutworms, cabbage loopers, dipterous leafminers, aphids, cucumber beetles and wireworms. …”
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  5. 745

    Insect Management for Leafy Vegetables (Lettuce, Endive and Escarole) by Gregg S. Nuessly, Susan E. Webb

    Published 2005-12-01
    “…Major pests of these crops are beet and southern armyworms, cutworms, cabbage loopers, dipterous leafminers, aphids, cucumber beetles and wireworms. …”
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  6. 746

    Jean-Antoine Chaptal (1756–1832), agronome et chimiste by Fournier, Josette

    Published 2024-04-01
    “…The chemist is remembered for his work on wine, the bleaching and dyeing of cotton, and the extraction of beet sugar. This manuscript is divided into two main parts, dealing successively with Jean-Antoine Chaptal’s student years until his appointment to the Consulate’s Ministry of the Interior, and then with the period from the Consulate to the July Monarchy.…”
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  7. 747

    Quantitative profiling of the vaginal microbiota improves resolution of the microbiota-immune axis by Eric Armstrong, Rachel Liu, James Pollock, Sanja Huibner, Suji Udayakumar, Erastus Irungu, Pauline Ngurukiri, Peter Muthoga, Wendy Adhiambo, Sergey Yegorov, Joshua Kimani, Tara Beattie, Bryan Coburn, Rupert Kaul

    Published 2025-02-01
    “…Results We analyzed cervicovaginal secretions from 196 female sex workers in Kenya and found that bacterial load was elevated among women with diverse, bacterial vaginosis (BV)-type microbiota and lower among women with Lactobacillus predominance. …”
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  8. 748

    Based on network pharmacology and molecular docking to study the mechanisms of active ingredients of ginseng in the treatment of atopic dermatitis by BU Jialiang, SHEN Lin, MENG Yuan, PIAO Yingshi

    Published 2025-01-01
    “…The GO functional enrichment showed that the biological processes were mainly involved in inflammatory response and regulation of secretion, etc., while the molecular function was mainly involved in the binding of nuclear receptor and cytokine receptors, etc. …”
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  9. 749

    Combination of potassium oxonate with anti-PD-1 for the treatment of colorectal cancer by Yuanyuan Wang, Chenxi Hu, Tianpeng Du, Jiawen Li, Kaiyuan Hui, Xiaodong Jiang

    Published 2025-02-01
    “…Moreover, IFN-γ and IL-2 secretion were found to be enriched in the tumor TME.ConclusionOur study indicated that combination of PO and anti-PD-1 could synergistically suppress CRC progression and altered the tumor microenvironment in favor of antitumor immune responses.…”
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  10. 750

    Nonylphenol exposure increases the risk of Hirschsprung’s disease by inducing macrophage M1 polarization by Xuefeng Yang, Chengyan Tang, Daiwei Zhu, Xingrong Xia, Qing Du, Lu Huang, Jianguo Liu, Yuanmei Liu

    Published 2025-01-01
    “…Nonylphenol (NP), a ubiquitous environmental contaminant used as a surfactant in industrial production and classified as an endocrine disruptor, could interfere hormone secretion and exhibit neurotoxicity in organisms. Hirschsprung’s disease (HSCR), one of the most frequently observed congenital malformations of the digestive system, arises mainly due to the failure of enteric neural crest cells to migrate to the distal colon during embryonic development. …”
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  11. 751

    Convergent origin and accelerated evolution of vesicle-associated RhoGAP proteins in two unrelated parasitoid wasps by Colinet, Dominique, Cavigliasso, Fanny, Leobold, Matthieu, Pichon, Apolline, Urbach, Serge, Cazes, Dominique, Poullet, Marine, Belghazi, Maya, Volkoff, Anne-Nathalie, Drezen, Jean-Michel, Gatti, Jean-Luc, Poirié, Marylène

    Published 2024-03-01
    “…Animal venoms and other protein-based secretions that perform a variety of functions, from predation to defense, are highly complex cocktails of bioactive compounds. …”
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  12. 752

    Glucagon-like peptide 1 receptor agonists in obesity treatment - a literature review by Aleksander Jentkiewicz, Esmail Haj Obeid, Jakub Ulrych, Jan Krupa, Maciej Malinowski, Michał Krasowski, Alicja Kalinowska, Wiktoria Pietras, Adrian Kozieł, Zofia Kurek

    Published 2025-02-01
    “…Gastric emptying and insulin secretion are also affected by GLP-1 RAs. Clinical trials consistently demonstrate significant weight loss, positive action on cardiovascular risk and better glycemic control. …”
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  13. 753

    Echinococcal Cyst Blockade — the Rare Cause of Acute Pancreatitis and Obstructive Jaundice by S. A. Budzinskiy, S. G. Shapovaliants, R. V. Plakhov, M. V. Murashkina, E. A. Vorobyeva, D. R. Berdieva, P. V. Usyaky, E. D. Fedorov

    Published 2023-11-01
    “…After non-annulation endoscopic papillotomy, migration of the substrate (echinococcal cyst) into the duodenum was noted, active flow of bile and pancreatic secretions was restored. Oral transpapillary cholangioscopy was performed for a detailed bile ducts examination. …”
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  14. 754

    RBD-displaying OMV nanovaccine boosts immunity against SARS-CoV-2 by Rang Feng, Ruo-Yi Xue, Chang Liu, Guo-Cheng Li, Yan Deng, Zhe Jin, Jing-Yi Liu, Shan-Shan Zhang, Hao Cheng, Man-Ying Guo, Quan-Ming Zou, Hai-Bo Li

    Published 2025-02-01
    “…Outer membrane vesicles (OMVs), secreted by Gram-negative bacteria, are nanospherical structures that can display or deliver antigens while also providing adjuvant activity through pathogen-associated molecular patterns (PAMPs). …”
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  15. 755

    Secure and energy-efficient inter- and intra-cluster optimization scheme for smart cities using UAV-assisted wireless sensor networks by Niayesh Gharaei, Aliaa M. Alabdali

    Published 2025-02-01
    “…Experimental evaluations demonstrate that SEI2 improves network lifetime by 35%, reduces compromised data packets by 19%, enhances coverage time by 15%, and significantly minimizes energy variance by 62% for CHs and 88% for MNs. …”
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  16. 756

    Exposure to perchlorate via drinking water from eight major water basins in China and its health risks across different age groups by Jia Lyu, Yongyan Chen, Lan Zhang, Xu Yan, Muyesaier Tudi

    Published 2025-02-01
    “…., emissions from the production of rockets and missiles, firework production was identified as the dominant source of perchlorate exposure via drinking water in this study. …”
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  17. 757

    Pathogenic and therapeutic role of bile acids at reflux-gastritis by T. L. Lapina, I. M. Kartavenko, V. T. Ivashkin

    Published 2015-03-01
    “…Increase of endocellular calcium stimulates secretion of pepsinogen and acid production in the stomach,  that in the case of decreased cytoprotective factors by DGR can cause changes mucosal injury. …”
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  18. 758

    Lipotoxicity and metabolic disorders at obesity by V. T. Ivashkin, M. V. Mayevskaya

    Published 2010-02-01
    “…In this aspect it is necessary to focus on glitazones (PPARs ligands), metformin among pharmacological substances, which has no influence on insulin secretion, however it has a lot of extrapancreatic effects by which it reduces increased concentrations of glucose in blood, improves tissue sensitivity to insulin and, thus, increases uptake of glucose by liver and muscles cells. …”
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  19. 759

    The Effect of Tumor Angiogenesis Agents on Tumor Growth Dynamics: A Mathematical Model by Ali Mohseni, Mohammad Pooyan, Somayeh Raiesdana, Mohammad Bagher Menhaj

    Published 2025-01-01
    “…Conclusion: Our results show the ineffectiveness of targeted treatments on the immune system, which has been confirmed by many negative treatment methods in immunotherapies. Tumor-secreted inhibitor factors are essential to regulating the angiogenesis process. …”
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  20. 760

    Biocompatibility of new cement based capping material prepared from eggshell and biopolymer (chitosan). by Hemn M. Sarmamy, Dara H. Saeed

    Published 2022-07-01
    “…The animals were divided into 3 groups, five rabbits for each group, for three time intervals (7, 14, and 21 days).Four specimens (4 mm long and 1 mm inner diameter) were inserted for each animal according to the following groups; Group 1: Empty pockets (control), Group 2: The Experimental material with a powder/liquid ratio of1 scoop: 8 drops by using glass slab with aid of cement metal spatula, Group 3: Mineral trioxide aggregate MTA which was mixed according to manufacturing instructions and Group 4: Biodentine which was mixed according to manufacturing instructions. …”
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